Motif ID: HNF1A.p2

Z-value: 0.788


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_121416294-0.441.5e-02Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_32497925 3.502 NM_002125
 HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr6_-_32557431 3.229 NM_001243965
NM_002124
 HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr4_-_110723127 2.303 CFI
complement factor I
chr10_+_114154522 2.273 ACSL5
acyl-CoA synthetase long-chain family member 5
chr14_-_94854910 2.107 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_110723334 2.067 NM_000204
 CFI
complement factor I
chr11_+_71900958 1.853 NM_000802
 FOLR1
folate receptor 1 (adult)
chr12_+_20963637 1.671 NM_019844
 SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_+_141695678 1.592 NM_004668
 MGAM
maltase-glucoamylase (alpha-glucosidase)
chr20_+_9288446 1.550 NM_000933
 PLCB4
phospholipase C, beta 4
chr14_-_94855120 1.540 NM_000295
 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_+_18807423 1.504 NM_152375
 KLHDC7A
kelch domain containing 7A
chr7_-_50633042 1.500 NM_001082971
 DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr17_+_4692226 1.428 NM_001014985
 GLTPD2
glycolipid transfer protein domain containing 2
chr12_-_71551564 1.405 TSPAN8
tetraspanin 8
chr15_-_90349819 1.347 ANPEP
alanyl (membrane) aminopeptidase
chr4_+_25658085 1.317 NM_001177999
 SLC34A2
solute carrier family 34 (sodium phosphate), member 2
chr4_-_100273831 1.312 NM_000669
 ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr4_+_69962191 1.309 NM_001074
 UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_+_21156922 1.191 NM_001097577
NM_194431
 ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
38.09 3.80e-02 GO:0044245 polysaccharide digestion
28.22 7.17e-03 GO:0009812 flavonoid metabolic process
23.09 1.83e-02 GO:0009698 phenylpropanoid metabolic process
13.23 3.12e-02 GO:0017144 drug metabolic process
8.12 3.25e-08 GO:0006805 xenobiotic metabolic process
8.12 3.25e-08 GO:0071466 cellular response to xenobiotic stimulus
8.06 3.68e-08 GO:0009410 response to xenobiotic stimulus
5.00 3.30e-02 GO:0006814 sodium ion transport
1.72 3.87e-02 GO:0042221 response to chemical stimulus

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
10.95 1.48e-02 GO:0031526 brush border membrane
9.88 1.10e-03 GO:0005903 brush border
8.55 2.96e-03 GO:0031983 vesicle lumen
8.11 1.64e-02 GO:0031093 platelet alpha granule lumen
7.94 1.85e-02 GO:0034774 secretory granule lumen
7.62 2.34e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
6.69 4.87e-02 GO:0031091 platelet alpha granule
5.67 1.25e-05 GO:0016324 apical plasma membrane
4.82 4.40e-05 GO:0045177 apical part of cell
2.39 3.43e-03 GO:0005615 extracellular space
2.31 3.31e-02 GO:0005789 endoplasmic reticulum membrane
2.25 4.63e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.23 2.93e-02 GO:0044432 endoplasmic reticulum part
2.04 2.48e-02 GO:0044421 extracellular region part
2.00 6.39e-06 GO:0044459 plasma membrane part
1.67 3.57e-02 GO:0005576 extracellular region
1.32 1.79e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
27.21 3.35e-02 GO:0005436 sodium:phosphate symporter activity
15.88 5.14e-05 GO:0015020 glucuronosyltransferase activity