Motif ID: IKZF1.p2

Z-value: 1.239


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF1chr7_+_503482550.451.2e-02Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_23261626 4.139 LOXL2
lysyl oxidase-like 2
chr8_-_23261591 3.962 LOXL2
lysyl oxidase-like 2
chr8_-_23261632 3.857 LOXL2
lysyl oxidase-like 2
chr16_+_23690234 3.765 PLK1
polo-like kinase 1
chr19_-_51456159 3.708 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr16_+_23690212 3.533 PLK1
polo-like kinase 1
chr2_-_113594325 3.140 NM_000576
IL1B
interleukin 1, beta
chr8_-_23261675 3.038 NM_002318
LOXL2
lysyl oxidase-like 2
chr16_+_23690190 2.627 PLK1
polo-like kinase 1
chr1_+_32042122 2.357 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr1_+_32042085 2.343 NM_001204414
NM_022164
TINAGL1

tubulointerstitial nephritis antigen-like 1

chr1_+_32042125 2.220 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr16_+_23690160 2.207 PLK1
polo-like kinase 1
chr16_+_23690191 2.175 NM_005030
PLK1
polo-like kinase 1
chr22_+_19467413 2.131 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr8_+_37887990 2.079 NM_004095
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr22_+_19467467 2.053 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr19_+_54371150 2.017 MYADM
myeloid-associated differentiation marker
chr19_+_54371125 2.006 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr8_+_48873533 2.002 MCM4
minichromosome maintenance complex component 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.54 4.65e-03 GO:0007155 cell adhesion
1.54 4.65e-03 GO:0022610 biological adhesion
1.43 4.54e-02 GO:0009611 response to wounding
1.35 2.43e-02 GO:0009966 regulation of signal transduction
1.30 2.80e-02 GO:0048583 regulation of response to stimulus
1.29 2.40e-05 GO:0034641 cellular nitrogen compound metabolic process
1.28 8.44e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 6.77e-05 GO:0006807 nitrogen compound metabolic process
1.26 4.94e-02 GO:0090304 nucleic acid metabolic process
1.25 3.01e-02 GO:0006950 response to stress
1.19 1.19e-02 GO:0051716 cellular response to stimulus
1.19 3.84e-02 GO:0023052 signaling
1.16 5.32e-04 GO:0044237 cellular metabolic process
1.14 1.53e-02 GO:0044238 primary metabolic process
1.13 2.35e-10 GO:0009987 cellular process
1.12 3.82e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.32 1.47e-04 GO:0005829 cytosol
1.13 2.50e-02 GO:0044444 cytoplasmic part
1.10 8.01e-03 GO:0005737 cytoplasm

Nothing significant found in function category.