Motif ID: KLF12.p2

Z-value: 1.585


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_747079130.356.1e-02Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_20915440 3.126 NM_001785
CDA
cytidine deaminase
chr11_-_1643324 2.309 NM_001012709
KRTAP5-4
keratin associated protein 5-4
chr19_-_51472816 2.244 NM_002774
KLK6
kallikrein-related peptidase 6
chr20_+_44637539 2.083 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_48262900 2.052 COL1A1
collagen, type I, alpha 1
chr9_+_34652125 2.024 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr15_-_74502045 1.928 NM_001199040
STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr17_-_39553796 1.872 NM_002277
KRT31
keratin 31
chr19_+_35645614 1.686 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_35645640 1.679 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr15_-_90039776 1.671 NM_016321
RHCG
Rh family, C glycoprotein
chr1_-_204120909 1.645 ETNK2
ethanolamine kinase 2
chr9_+_35673852 1.637 NM_001216
CA9
carbonic anhydrase IX
chr20_-_36758362 1.598 TGM2
transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr7_+_143013218 1.594 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr5_-_39203061 1.588 FYB
FYN binding protein
chr9_+_131185129 1.538 CERCAM
cerebral endothelial cell adhesion molecule
chr22_-_37640287 1.532 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr7_-_75623888 1.515 TMEM120A
transmembrane protein 120A
chr2_+_70142236 1.479 MXD1
MAX dimerization protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 87 entries
enrichment   p-value GO term description
2.68 3.20e-02 GO:0007044 cell-substrate junction assembly
2.08 3.63e-04 GO:0040013 negative regulation of locomotion
2.06 5.53e-03 GO:0030336 negative regulation of cell migration
2.06 5.53e-03 GO:2000146 negative regulation of cell motility
2.01 6.37e-03 GO:0051271 negative regulation of cellular component movement
1.77 4.14e-03 GO:0034330 cell junction organization
1.68 2.53e-02 GO:0009952 anterior/posterior pattern formation
1.62 2.00e-04 GO:0001944 vasculature development
1.61 8.79e-03 GO:0048514 blood vessel morphogenesis
1.58 1.02e-03 GO:0051270 regulation of cellular component movement
1.58 3.42e-03 GO:0030334 regulation of cell migration
1.57 1.63e-03 GO:0040012 regulation of locomotion
1.57 3.75e-03 GO:0001568 blood vessel development
1.57 6.38e-03 GO:2000145 regulation of cell motility
1.56 1.59e-02 GO:0030036 actin cytoskeleton organization
1.53 1.40e-03 GO:0007411 axon guidance
1.53 9.01e-03 GO:0030029 actin filament-based process
1.49 1.54e-03 GO:0007264 small GTPase mediated signal transduction
1.45 2.79e-03 GO:0048812 neuron projection morphogenesis
1.45 4.59e-03 GO:0007409 axonogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
2.26 4.21e-03 GO:0043197 dendritic spine
2.17 1.11e-02 GO:0044309 neuron spine
1.86 3.76e-02 GO:0033267 axon part
1.85 4.08e-03 GO:0005925 focal adhesion
1.80 7.57e-03 GO:0005924 cell-substrate adherens junction
1.79 1.68e-04 GO:0005912 adherens junction
1.78 1.00e-02 GO:0030055 cell-substrate junction
1.72 4.66e-04 GO:0070161 anchoring junction
1.63 3.07e-03 GO:0031252 cell leading edge
1.61 6.71e-03 GO:0030424 axon
1.57 1.08e-02 GO:0030425 dendrite
1.50 7.62e-04 GO:0044433 cytoplasmic vesicle part
1.50 2.01e-03 GO:0015629 actin cytoskeleton
1.49 2.44e-02 GO:0016323 basolateral plasma membrane
1.44 4.56e-02 GO:0012506 vesicle membrane
1.41 3.97e-03 GO:0043005 neuron projection
1.37 4.16e-02 GO:0031012 extracellular matrix
1.32 4.91e-04 GO:0031410 cytoplasmic vesicle
1.32 6.32e-04 GO:0031982 vesicle
1.31 2.72e-03 GO:0016023 cytoplasmic membrane-bounded vesicle

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.05 3.98e-03 GO:0005200 structural constituent of cytoskeleton
1.65 3.98e-02 GO:0005516 calmodulin binding
1.55 1.09e-04 GO:0003779 actin binding
1.42 1.87e-04 GO:0008092 cytoskeletal protein binding
1.38 1.52e-02 GO:0019904 protein domain specific binding
1.15 2.38e-16 GO:0005515 protein binding
1.07 2.34e-11 GO:0005488 binding