Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.112


Transcription factors associated with LEF1_TCF7_TCF7L1,2.p2:

Gene SymbolEntrez IDGene Name
LEF1 51176 lymphoid enhancer-binding factor 1
TCF7 6932 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 83439 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF7chr5_+_1334512970.495.6e-03Click!
LEF1chr4_-_109089444-0.479.5e-03Click!
TCF7L1chr2_+_85360373-0.374.5e-02Click!
TCF7L2chr10_+_1147107850.355.6e-02Click!


Activity profile for motif LEF1_TCF7_TCF7L1,2.p2.

activity profile for motif LEF1_TCF7_TCF7L1,2.p2


Sorted Z-values histogram for motif LEF1_TCF7_TCF7L1,2.p2

Sorted Z-values for motif LEF1_TCF7_TCF7L1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LEF1_TCF7_TCF7L1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_31870940 7.535 NM_033197
 BPIFB1
BPI fold containing family B, member 1
chr9_-_34381497 5.331 NM_001252195
NM_147168
NM_147169
 C9orf24


chromosome 9 open reading frame 24


chr6_-_29527701 5.146 NM_006398
 UBD
ubiquitin D
chr6_-_29527477 5.084 UBD
ubiquitin D
chr2_-_135782246 3.844 NM_001018046
NM_025052
 YSK4

YSK4 Sps1/Ste20-related kinase homolog (S. cerevisiae)

chr13_+_24144402 3.693 NM_001204459
NM_148957
 TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr19_-_7990974 3.272 NM_206833
 CTXN1
cortexin 1
chr19_-_41356193 3.043 NM_000762
 CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr19_-_3028901 2.916 NM_003260
 TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr14_+_74486049 2.908 NM_025057
 C14orf45
chromosome 14 open reading frame 45
chr4_-_16077740 2.855 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
 PROM1




prominin 1




chr2_+_172378756 2.668 CYBRD1
cytochrome b reductase 1
chr5_-_100238870 2.637 NM_175052
NM_005668
 ST8SIA4

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4

chr18_+_61370193 2.596 NM_080475
 SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr13_-_39564857 2.576 NM_001144033
NM_145286
 STOML3

stomatin (EPB72)-like 3

chr17_-_63557764 2.473 AXIN2
axin 2
chr17_-_63556443 2.419 AXIN2
axin 2
chr3_-_148939784 2.412 NM_000096
 CP
ceruloplasmin (ferroxidase)
chr17_-_63557615 2.246 NM_004655
 AXIN2
axin 2
chr14_-_21271002 2.227 NM_002933
NM_198234
NM_198235
 RNASE1


ribonuclease, RNase A family, 1 (pancreatic)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.64 1.60e-02 GO:0007156 homophilic cell adhesion

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.17 1.67e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.32 8.17e-03 GO:0003677 DNA binding