Motif ID: MAFB.p2

Z-value: 1.611


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_393178750.029.1e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_76425207 2.283 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr3_-_45267068 2.172 TMEM158
transmembrane protein 158 (gene/pseudogene)
chrX_+_68725077 2.127 NM_015686
 FAM155B
family with sequence similarity 155, member B
chr8_+_102504836 1.838 GRHL2
grainyhead-like 2 (Drosophila)
chr9_-_85677784 1.836 RASEF
RAS and EF-hand domain containing
chr2_+_191745546 1.797 NM_014905
 GLS
glutaminase
chr17_+_7210841 1.583 NM_001970
 EIF5A
eukaryotic translation initiation factor 5A
chr2_+_191745912 1.577 GLS
glutaminase
chr7_-_27183225 1.555 NM_019102
 HOXA5
homeobox A5
chr4_+_75858205 1.516 NM_015393
 PARM1
prostate androgen-regulated mucin-like protein 1
chrX_+_44732402 1.513 NM_021140
 KDM6A
lysine (K)-specific demethylase 6A
chr16_+_82660573 1.468 CDH13
cadherin 13, H-cadherin (heart)
chr16_+_82660390 1.458 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
 CDH13





cadherin 13, H-cadherin (heart)





chr7_-_76256475 1.457 NM_012230
NM_152992
 POMZP3

POM121 and ZP3 fusion

chr3_+_109128836 1.411 NM_001145553
 FLJ25363
uncharacterized LOC401082
chr2_-_193059249 1.346 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr2_+_191745547 1.342 GLS
glutaminase
chr7_+_145813452 1.333 NM_014141
 CNTNAP2
contactin associated protein-like 2
chr8_+_102504661 1.314 NM_024915
 GRHL2
grainyhead-like 2 (Drosophila)
chr17_+_7210929 1.300 EIF5A
eukaryotic translation initiation factor 5A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 180 entries
enrichment   p-value GO term description
1.83 4.76e-03 GO:0008286 insulin receptor signaling pathway
1.80 4.33e-04 GO:0032869 cellular response to insulin stimulus
1.78 3.38e-03 GO:0006813 potassium ion transport
1.71 1.01e-02 GO:0043687 post-translational protein modification
1.70 7.45e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.70 5.64e-03 GO:0034220 ion transmembrane transport
1.69 9.43e-04 GO:0071375 cellular response to peptide hormone stimulus
1.66 1.53e-02 GO:0048732 gland development
1.65 4.27e-03 GO:0009261 ribonucleotide catabolic process
1.64 3.73e-09 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.64 5.74e-03 GO:0009154 purine ribonucleotide catabolic process
1.63 1.03e-02 GO:0009203 ribonucleoside triphosphate catabolic process
1.63 1.03e-02 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.62 8.15e-03 GO:0032868 response to insulin stimulus
1.62 1.18e-02 GO:0009143 nucleoside triphosphate catabolic process
1.62 1.28e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.61 5.89e-08 GO:0000904 cell morphogenesis involved in differentiation
1.61 5.91e-03 GO:0006195 purine nucleotide catabolic process
1.60 8.01e-04 GO:0009199 ribonucleoside triphosphate metabolic process
1.59 4.16e-06 GO:0048667 cell morphogenesis involved in neuron differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
1.61 1.28e-02 GO:0031252 cell leading edge
1.47 2.74e-02 GO:0012506 vesicle membrane
1.45 2.11e-03 GO:0043005 neuron projection
1.44 7.34e-04 GO:0005768 endosome
1.44 2.59e-03 GO:0045202 synapse
1.43 3.10e-02 GO:0044433 cytoplasmic vesicle part
1.42 2.43e-02 GO:0048471 perinuclear region of cytoplasm
1.34 1.02e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 7.95e-04 GO:0031410 cytoplasmic vesicle
1.33 1.24e-03 GO:0031988 membrane-bounded vesicle
1.32 9.17e-04 GO:0031982 vesicle
1.29 6.91e-03 GO:0005626 insoluble fraction
1.27 2.44e-02 GO:0005624 membrane fraction
1.26 3.15e-03 GO:0000267 cell fraction
1.26 6.69e-03 GO:0005794 Golgi apparatus
1.24 2.43e-06 GO:0005829 cytosol
1.23 7.92e-04 GO:0012505 endomembrane system
1.20 7.91e-07 GO:0043234 protein complex
1.19 1.98e-03 GO:0031090 organelle membrane
1.16 1.04e-11 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
1.97 4.11e-02 GO:0005200 structural constituent of cytoskeleton
1.87 2.54e-02 GO:0017016 Ras GTPase binding
1.73 2.50e-02 GO:0005267 potassium channel activity
1.47 2.94e-02 GO:0005083 small GTPase regulator activity
1.41 9.67e-04 GO:0008092 cytoskeletal protein binding
1.38 6.38e-05 GO:0019899 enzyme binding
1.38 2.43e-02 GO:0030695 GTPase regulator activity
1.37 5.12e-04 GO:0043565 sequence-specific DNA binding
1.34 8.77e-03 GO:0004672 protein kinase activity
1.32 1.40e-04 GO:0001071 nucleic acid binding transcription factor activity
1.32 1.40e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 7.15e-03 GO:0016301 kinase activity
1.31 1.35e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.28 3.74e-06 GO:0032559 adenyl ribonucleotide binding
1.28 2.99e-03 GO:0030528 transcription regulator activity
1.27 5.02e-07 GO:0032553 ribonucleotide binding
1.27 5.02e-07 GO:0032555 purine ribonucleotide binding
1.27 7.96e-06 GO:0030554 adenyl nucleotide binding
1.26 8.72e-07 GO:0017076 purine nucleotide binding
1.26 7.38e-05 GO:0005524 ATP binding