Motif ID: MAZ.p2

Z-value: 1.597


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.232.1e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_158380360 10.952 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_-_3028901 10.912 NM_003260
 TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_+_708766 10.785 NM_001040134
NM_002579
 PALM

paralemmin

chr1_+_205538111 8.517 NM_181644
 MFSD4
major facilitator superfamily domain containing 4
chr16_+_67465019 6.812 NM_000196
 HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr6_-_29595746 6.394 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_52580805 6.273 NM_001080430
 TOX3
TOX high mobility group box family member 3
chr19_-_7990974 6.138 NM_206833
 CTXN1
cortexin 1
chr1_+_205538164 6.119 MFSD4
major facilitator superfamily domain containing 4
chrX_+_119029799 5.940 NM_001008534
NM_001008535
NM_178813
 AKAP14


A kinase (PRKA) anchor protein 14


chr4_+_1005609 5.272 NM_001004356
NM_001004358
 FGFRL1

fibroblast growth factor receptor-like 1

chr11_+_61276271 5.065 NM_001145077
 LRRC10B
leucine rich repeat containing 10B
chr7_-_51384458 4.866 NM_015198
 COBL
cordon-bleu homolog (mouse)
chr16_-_67427335 4.781 NM_015964
NM_016140
 TPPP3

tubulin polymerization-promoting protein family member 3

chr1_-_22469414 4.655 NM_030761
 WNT4
wingless-type MMTV integration site family, member 4
chr14_-_65438794 4.615 NM_198686
 RAB15
RAB15, member RAS onocogene family
chr14_-_95786095 4.596 NM_024734
 CLMN
calmin (calponin-like, transmembrane)
chr12_+_7013896 4.571 NM_001135217
NM_006992
NM_201650
 LRRC23


leucine rich repeat containing 23


chr18_+_77155927 4.458 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_291335 4.435 NM_003712
NM_177526
 PPAP2C

phosphatidic acid phosphatase type 2C


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 140 entries
enrichment   p-value GO term description
1.63 1.92e-02 GO:0018205 peptidyl-lysine modification
1.54 1.54e-05 GO:0016569 covalent chromatin modification
1.54 2.29e-05 GO:0016570 histone modification
1.52 6.99e-12 GO:0016568 chromatin modification
1.41 2.74e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.37 4.91e-07 GO:0006325 chromatin organization
1.34 9.85e-08 GO:0051276 chromosome organization
1.33 6.98e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.33 4.73e-02 GO:0007346 regulation of mitotic cell cycle
1.31 8.58e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.31 4.49e-06 GO:0010629 negative regulation of gene expression
1.31 6.52e-03 GO:0009792 embryo development ending in birth or egg hatching
1.31 1.42e-02 GO:0012502 induction of programmed cell death
1.31 1.88e-02 GO:0006917 induction of apoptosis
1.30 1.80e-06 GO:0030182 neuron differentiation
1.30 1.96e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 3.18e-05 GO:0048666 neuron development
1.30 3.20e-04 GO:0031175 neuron projection development
1.30 1.64e-03 GO:0048812 neuron projection morphogenesis
1.30 1.17e-02 GO:0043009 chordate embryonic development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
1.63 2.21e-02 GO:0030426 growth cone
1.62 2.40e-02 GO:0030427 site of polarized growth
1.57 2.02e-03 GO:0005925 focal adhesion
1.54 3.66e-03 GO:0005924 cell-substrate adherens junction
1.53 3.95e-03 GO:0030055 cell-substrate junction
1.41 1.89e-04 GO:0016323 basolateral plasma membrane
1.40 3.33e-02 GO:0005912 adherens junction
1.38 2.11e-02 GO:0044454 nuclear chromosome part
1.37 4.30e-03 GO:0000228 nuclear chromosome
1.34 1.83e-02 GO:0016604 nuclear body
1.32 3.12e-09 GO:0044451 nucleoplasm part
1.27 1.11e-04 GO:0005694 chromosome
1.26 3.20e-02 GO:0048471 perinuclear region of cytoplasm
1.25 8.35e-03 GO:0044427 chromosomal part
1.25 2.39e-02 GO:0045202 synapse
1.24 4.73e-10 GO:0005654 nucleoplasm
1.22 6.73e-13 GO:0031981 nuclear lumen
1.22 7.55e-03 GO:0030054 cell junction
1.21 1.61e-13 GO:0044428 nuclear part
1.19 4.11e-12 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
1.56 4.29e-02 GO:0031625 ubiquitin protein ligase binding
1.55 6.55e-03 GO:0005057 receptor signaling protein activity
1.44 5.56e-04 GO:0010843 promoter binding
1.42 1.15e-03 GO:0000975 regulatory region DNA binding
1.42 1.15e-03 GO:0001067 regulatory region nucleic acid binding
1.42 1.15e-03 GO:0044212 transcription regulatory region DNA binding
1.35 1.80e-06 GO:0019904 protein domain specific binding
1.35 5.31e-04 GO:0016563 transcription activator activity
1.31 3.86e-08 GO:0043565 sequence-specific DNA binding
1.30 1.83e-03 GO:0000988 protein binding transcription factor activity
1.30 1.83e-03 GO:0000989 transcription factor binding transcription factor activity
1.30 2.40e-03 GO:0003712 transcription cofactor activity
1.30 3.42e-02 GO:0008134 transcription factor binding
1.29 2.80e-02 GO:0016564 transcription repressor activity
1.27 1.77e-06 GO:0019899 enzyme binding
1.27 5.83e-03 GO:0004674 protein serine/threonine kinase activity
1.26 3.09e-08 GO:0030528 transcription regulator activity
1.23 2.46e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.23 3.55e-03 GO:0004672 protein kinase activity
1.22 9.32e-06 GO:0001071 nucleic acid binding transcription factor activity