Motif ID: MAZ.p2

Z-value: 1.597


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_29817810-0.232.1e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_158380360 10.952 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_-_3028901 10.912 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_+_708766 10.785 NM_001040134
NM_002579
PALM

paralemmin

chr1_+_205538111 8.517 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr16_+_67465019 6.812 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr6_-_29595746 6.394 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr16_-_52580805 6.273 NM_001080430
TOX3
TOX high mobility group box family member 3
chr19_-_7990974 6.138 NM_206833
CTXN1
cortexin 1
chr1_+_205538164 6.119 MFSD4
major facilitator superfamily domain containing 4
chrX_+_119029799 5.940 NM_001008534
NM_001008535
NM_178813
AKAP14


A kinase (PRKA) anchor protein 14


chr4_+_1005609 5.272 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr11_+_61276271 5.065 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr7_-_51384458 4.866 NM_015198
COBL
cordon-bleu homolog (mouse)
chr16_-_67427335 4.781 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr1_-_22469414 4.655 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr14_-_65438794 4.615 NM_198686
RAB15
RAB15, member RAS onocogene family
chr14_-_95786095 4.596 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr12_+_7013896 4.571 NM_001135217
NM_006992
NM_201650
LRRC23


leucine rich repeat containing 23


chr18_+_77155927 4.458 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_291335 4.435 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr1_+_245133652 4.326 EFCAB2
EF-hand calcium binding domain 2
chr4_-_1166458 4.307 SPON2
spondin 2, extracellular matrix protein
chr2_+_120189342 4.281 NM_183240
TMEM37
transmembrane protein 37
chr4_-_1166364 4.210 SPON2
spondin 2, extracellular matrix protein
chr8_+_144635556 4.057 NM_001166237
GSDMD
gasdermin D
chr2_+_11295539 3.975 NM_152391
PQLC3
PQ loop repeat containing 3
chr2_+_11295569 3.931 PQLC3
PQ loop repeat containing 3
chr9_-_3525721 3.905 RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr4_-_1166547 3.849 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr18_+_77155966 3.830 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr19_-_291168 3.774 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr1_+_211432693 3.677 NM_001136223
NM_001136224
NM_001136225
RCOR3


REST corepressor 3


chr4_-_1166378 3.665 SPON2
spondin 2, extracellular matrix protein
chr6_-_90121656 3.647 RRAGD
Ras-related GTP binding D
chr7_-_51384331 3.643 COBL
cordon-bleu homolog (mouse)
chr16_-_54320367 3.538 NM_024336
IRX3
iroquois homeobox 3
chr21_-_45759077 3.535 C21orf2
chromosome 21 open reading frame 2
chr3_+_58223415 3.533 ABHD6
abhydrolase domain containing 6
chr19_-_821966 3.517 LPPR3
lipid phosphate phosphatase-related protein type 3
chr1_+_245133628 3.482 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr2_-_230579198 3.414 NM_139072
DNER
delta/notch-like EGF repeat containing
chr6_+_17281773 3.408 NM_001143942
RBM24
RNA binding motif protein 24
chr1_-_23810627 3.404 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr5_+_139028025 3.383 NM_016463
CXXC5
CXXC finger protein 5
chr2_+_106682111 3.381 NM_032411
C2orf40
chromosome 2 open reading frame 40
chr19_+_4639526 3.342 NM_152362
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr17_+_55333843 3.330 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr6_+_43612766 3.265 NM_001193341
NM_152732
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr7_+_152161119 3.231 LOC100128822
uncharacterized LOC100128822
chr19_+_14544216 3.179 PKN1
protein kinase N1
chr6_+_19837599 3.156 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr16_-_1968230 3.116 NM_001009606
HS3ST6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr4_-_1166959 3.110 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr12_-_48744553 3.092 NM_001172681
NM_152320
ZNF641

zinc finger protein 641

chrX_+_9432980 3.071 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr2_+_8822112 3.029 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr11_-_119234628 3.017 USP2
ubiquitin specific peptidase 2
chr4_-_149363498 3.015 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr1_+_210406194 3.008 NM_019605
SERTAD4
SERTA domain containing 4
chr10_+_76586299 3.005 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr13_-_114018365 2.939 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr11_+_73358593 2.922 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr7_-_73184535 2.907 NM_001306
CLDN3
claudin 3
chr11_+_2466171 2.897 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr14_-_89883306 2.888 NM_005197
FOXN3
forkhead box N3
chr10_+_12391728 2.854 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr15_-_93632161 2.843 NM_020211
RGMA
RGM domain family, member A
chr9_+_71320105 2.800 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr19_-_14316980 2.790 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr11_-_119234859 2.777 NM_171997
USP2
ubiquitin specific peptidase 2
chr10_+_135192694 2.759 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr4_+_55523906 2.757 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr3_+_58223228 2.755 NM_020676
ABHD6
abhydrolase domain containing 6
chr21_+_42688660 2.746 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chr2_+_24299751 2.743 LOC375190
UPF0638 protein B
chr1_+_118148506 2.728 NM_017709
FAM46C
family with sequence similarity 46, member C
chr1_+_118148668 2.722 FAM46C
family with sequence similarity 46, member C
chr11_+_45907198 2.721 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr20_-_40246991 2.717 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr16_+_69600110 2.716 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr6_-_24911194 2.716 NM_014722
FAM65B
family with sequence similarity 65, member B
chr1_+_211432855 2.708 RCOR3
REST corepressor 3
chr16_-_54320328 2.681 IRX3
iroquois homeobox 3
chr19_+_50094911 2.667 NM_020719
PRR12
proline rich 12
chr3_-_13008959 2.647 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr18_+_77155714 2.629 NM_006162
NM_172388
NM_172390
NFATC1


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1


chr18_-_45935627 2.626 ZBTB7C
zinc finger and BTB domain containing 7C
chr21_+_44073650 2.621 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr2_-_99758034 2.576 NM_182911
TSGA10
testis specific, 10
chr19_-_17137449 2.518 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr1_-_23810721 2.499 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr22_+_39853316 2.484 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr7_+_73442451 2.473 ELN
elastin
chr3_+_238535 2.458 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr7_+_73442486 2.451 ELN
elastin
chr4_+_72052354 2.414 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr6_-_31846751 2.400 SLC44A4
solute carrier family 44, member 4
chr7_+_73442426 2.388 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr10_+_12391708 2.384 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr16_-_88923233 2.382 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr19_-_821913 2.366 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr8_+_144329105 2.347 NM_173832
ZFP41
zinc finger protein 41 homolog (mouse)
chr13_+_35516390 2.331 NM_015678
NBEA
neurobeachin
chr1_-_67390413 2.315 NM_024763
NM_207014
WDR78

WD repeat domain 78

chr1_-_227505796 2.301 NM_003607
NM_014826
CDC42BPA

CDC42 binding protein kinase alpha (DMPK-like)

chr1_+_151483861 2.297 NM_020770
CGN
cingulin
chr10_+_82116557 2.295 NM_032372
DYDC2
DPY30 domain containing 2
chr19_-_3029611 2.284 NM_001144762
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr5_-_137368778 2.275 NM_001101800
NM_001101801
NM_016603
FAM13B


family with sequence similarity 13, member B


chr5_+_122424840 2.254 NM_001136239
PRDM6
PR domain containing 6
chr22_+_39853534 2.251 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr20_-_55841090 2.249 BMP7
bone morphogenetic protein 7
chr12_-_48745020 2.241 NM_001172682
ZNF641
zinc finger protein 641
chr8_+_144798494 2.202 NM_139021
MAPK15
mitogen-activated protein kinase 15
chr11_-_119076888 2.179 CCDC153
coiled-coil domain containing 153
chr19_+_14544100 2.176 NM_002741
PKN1
protein kinase N1
chr11_+_111385509 2.152 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr3_+_13590644 2.151 FBLN2
fibulin 2
chr3_+_13590624 2.147 NM_001004019
NM_001998
FBLN2

fibulin 2

chr2_-_61697899 2.144 USP34
ubiquitin specific peptidase 34
chr16_+_69599869 2.139 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr13_+_25254548 2.129 NM_001185085
NM_001676
ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

chr7_+_21467572 2.126 NM_003112
SP4
Sp4 transcription factor
chr14_-_92414004 2.123 NM_006329
FBLN5
fibulin 5
chr7_-_152133071 2.095 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_230787195 2.090 NM_174899
FBXO36
F-box protein 36
chr1_-_223537400 2.077 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr15_-_75743776 2.065 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr1_+_164528586 2.062 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr6_+_17282294 2.061 NM_001143941
RBM24
RNA binding motif protein 24
chr19_+_8274179 2.061 NM_024552
CERS4
ceramide synthase 4
chr11_+_118307072 2.047 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr10_-_21462987 2.000 NEBL
nebulette
chr17_-_42296923 1.992 UBTF
upstream binding transcription factor, RNA polymerase I
chr5_+_139028483 1.986 CXXC5
CXXC finger protein 5
chr3_+_132441068 1.975 NPHP3-AS1
NPHP3 antisense RNA 1 (non-protein coding)
chr20_-_3149070 1.967 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr22_+_29279573 1.962 NM_001206998
ZNRF3
zinc and ring finger 3
chr16_-_66959418 1.949 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr9_-_117160748 1.947 AKNA
AT-hook transcription factor
chr16_+_2588000 1.941 PDPK1
3-phosphoinositide dependent protein kinase-1
chr1_+_222791151 1.925 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr8_-_23177481 1.917 LOXL2
lysyl oxidase-like 2
chr8_-_110657025 1.914 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr3_-_47620186 1.913 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr10_+_95753684 1.909 NM_016341
PLCE1
phospholipase C, epsilon 1
chr17_-_80231240 1.904 CSNK1D
casein kinase 1, delta
chr2_-_16847070 1.876 NM_030797
FAM49A
family with sequence similarity 49, member A
chr14_+_105953256 1.871 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr2_+_149402321 1.869 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr11_+_1244292 1.864 NM_002458
MUC5B
mucin 5B, oligomeric mucus/gel-forming
chr1_+_183605207 1.855 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr11_+_65479685 1.853 KAT5
K(lysine) acetyltransferase 5
chr3_+_52444514 1.835 NM_016483
NM_173341
PHF7

PHD finger protein 7

chr19_+_41305333 1.835 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr14_+_56584854 1.834 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr11_+_65292576 1.824 SCYL1
SCY1-like 1 (S. cerevisiae)
chr14_+_56585147 1.812 PELI2
pellino homolog 2 (Drosophila)
chr17_+_36861398 1.803 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr5_+_139027955 1.801 CXXC5
CXXC finger protein 5
chr11_+_48002063 1.797 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr10_-_21463019 1.777 NM_001173484
NM_213569
NEBL

nebulette

chr16_+_2587989 1.776 PDPK1
3-phosphoinositide dependent protein kinase-1
chr16_-_67700571 1.774 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr12_+_6420098 1.772 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr19_-_17007674 1.768 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr20_+_51588945 1.747 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr12_+_50451486 1.746 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr17_-_3867585 1.743 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr2_+_85980600 1.742 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr8_-_143858436 1.740 NM_177476
NM_177477
LYNX1

Ly6/neurotoxin 1

chr19_+_3094528 1.739 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr7_+_69064316 1.734 AUTS2
autism susceptibility candidate 2
chr10_+_12391471 1.732 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr17_+_29718777 1.725 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr6_-_90121911 1.721 RRAGD
Ras-related GTP binding D
chr2_-_60780404 1.714 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr14_+_105953531 1.712 CRIP1
cysteine-rich protein 1 (intestinal)
chr21_-_45759234 1.708 C21orf2
chromosome 21 open reading frame 2
chr4_-_25864430 1.703 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chrX_-_8700170 1.694 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr11_+_113930296 1.689 ZBTB16
zinc finger and BTB domain containing 16
chr1_-_167906277 1.689 NM_001143674
NM_015415
BRP44

brain protein 44

chr17_+_62075710 1.687 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr3_+_169755782 1.681 GPR160
G protein-coupled receptor 160
chr19_-_44143943 1.681 NM_145296
CADM4
cell adhesion molecule 4
chr11_+_113930430 1.681 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr2_-_159312955 1.679 NM_001171637
NM_138803
CCDC148

coiled-coil domain containing 148

chr1_+_15250578 1.676 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr11_-_130184459 1.675 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr3_-_9994057 1.675 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr1_+_87794548 1.673 LMO4
LIM domain only 4
chr6_-_134496006 1.669 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr15_+_73344824 1.660 NM_001172623
NM_001172624
NM_002499
NEO1


neogenin 1


chr9_+_136325086 1.660 NM_001135775
NM_001242369
NM_001242370
NM_017586
C9orf7



chromosome 9 open reading frame 7



chr2_-_211035913 1.659 NM_152519
C2orf67
chromosome 2 open reading frame 67
chr7_-_130080823 1.654 NM_018718
CEP41
centrosomal protein 41kDa
chr12_-_49582800 1.652 NM_006009
TUBA1A
tubulin, alpha 1a
chr19_-_55677919 1.651 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr6_-_79787784 1.647 PHIP
pleckstrin homology domain interacting protein

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 2.29e-26 GO:0009987 cellular process
1.16 3.87e-17 GO:0044260 cellular macromolecule metabolic process
1.12 1.48e-15 GO:0044237 cellular metabolic process
1.14 2.56e-15 GO:0043170 macromolecule metabolic process
1.11 1.70e-13 GO:0044238 primary metabolic process
1.10 1.14e-12 GO:0050794 regulation of cellular process
1.09 1.36e-12 GO:0065007 biological regulation
1.52 6.99e-12 GO:0016568 chromatin modification
1.09 1.35e-11 GO:0050789 regulation of biological process
1.18 2.85e-11 GO:0048518 positive regulation of biological process
1.16 2.89e-11 GO:0016043 cellular component organization
1.09 3.42e-11 GO:0008152 metabolic process
1.15 2.07e-10 GO:0071840 cellular component organization or biogenesis
1.18 4.30e-10 GO:0048522 positive regulation of cellular process
1.15 1.36e-09 GO:0060255 regulation of macromolecule metabolic process
1.14 1.97e-09 GO:0032502 developmental process
1.19 2.47e-09 GO:0048523 negative regulation of cellular process
1.18 3.34e-09 GO:0048519 negative regulation of biological process
1.17 3.64e-09 GO:0071842 cellular component organization at cellular level
1.14 1.28e-08 GO:0031323 regulation of cellular metabolic process
1.14 1.60e-08 GO:0007275 multicellular organismal development
1.16 1.74e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 2.04e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.52e-08 GO:0044267 cellular protein metabolic process
1.28 3.06e-08 GO:0048468 cell development
1.18 3.13e-08 GO:0090304 nucleic acid metabolic process
1.13 4.91e-08 GO:0080090 regulation of primary metabolic process
1.12 5.07e-08 GO:0019222 regulation of metabolic process
1.14 5.47e-08 GO:0006807 nitrogen compound metabolic process
1.14 6.67e-08 GO:0034641 cellular nitrogen compound metabolic process
1.21 9.33e-08 GO:0007399 nervous system development
1.14 9.70e-08 GO:0048856 anatomical structure development
1.34 9.85e-08 GO:0051276 chromosome organization
1.27 1.02e-07 GO:0009892 negative regulation of metabolic process
1.16 1.95e-07 GO:0010468 regulation of gene expression
1.18 2.02e-07 GO:0030154 cell differentiation
1.17 3.50e-07 GO:0048869 cellular developmental process
1.19 3.99e-07 GO:0009059 macromolecule biosynthetic process
1.37 4.91e-07 GO:0006325 chromatin organization
1.19 5.53e-07 GO:0034645 cellular macromolecule biosynthetic process
1.14 5.54e-07 GO:0048731 system development
1.26 5.74e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.20 6.80e-07 GO:0006996 organelle organization
1.31 8.58e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.30 1.80e-06 GO:0030182 neuron differentiation
1.25 3.04e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.25 3.04e-06 GO:0022008 neurogenesis
1.19 3.39e-06 GO:0023051 regulation of signaling
1.15 3.74e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.31 4.49e-06 GO:0010629 negative regulation of gene expression
1.22 5.69e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.25 6.89e-06 GO:0031324 negative regulation of cellular metabolic process
1.33 6.98e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.18 8.27e-06 GO:0016070 RNA metabolic process
1.26 8.34e-06 GO:0048699 generation of neurons
1.14 9.95e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.54 1.54e-05 GO:0016569 covalent chromatin modification
1.14 1.64e-05 GO:0009058 biosynthetic process
1.30 1.96e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 2.10e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.54 2.29e-05 GO:0016570 histone modification
1.14 2.81e-05 GO:0044249 cellular biosynthetic process
1.28 2.93e-05 GO:0009790 embryo development
1.16 3.05e-05 GO:0006464 protein modification process
1.30 3.18e-05 GO:0048666 neuron development
1.16 3.26e-05 GO:0010467 gene expression
1.27 3.55e-05 GO:0009890 negative regulation of biosynthetic process
1.24 3.68e-05 GO:0006351 transcription, DNA-dependent
1.13 3.69e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 4.41e-05 GO:0019538 protein metabolic process
1.16 4.64e-05 GO:0043412 macromolecule modification
1.14 5.29e-05 GO:0051252 regulation of RNA metabolic process
1.27 5.53e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.20 5.71e-05 GO:0009893 positive regulation of metabolic process
1.29 6.25e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.13 1.03e-04 GO:0031326 regulation of cellular biosynthetic process
1.18 1.53e-04 GO:0009653 anatomical structure morphogenesis
1.27 1.56e-04 GO:0010628 positive regulation of gene expression
1.28 1.56e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.13 1.59e-04 GO:0009889 regulation of biosynthetic process
1.18 1.88e-04 GO:0009966 regulation of signal transduction
1.11 2.02e-04 GO:0051179 localization
1.23 2.02e-04 GO:0016265 death
1.29 2.12e-04 GO:0051253 negative regulation of RNA metabolic process
1.22 2.17e-04 GO:0032774 RNA biosynthetic process
1.29 2.45e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.19 2.91e-04 GO:0031325 positive regulation of cellular metabolic process
1.30 3.20e-04 GO:0031175 neuron projection development
1.23 3.24e-04 GO:0008219 cell death
1.10 3.38e-04 GO:0023052 signaling
1.14 4.20e-04 GO:0006355 regulation of transcription, DNA-dependent
1.26 4.21e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.24 8.10e-04 GO:0016192 vesicle-mediated transport
1.20 8.85e-04 GO:0010646 regulation of cell communication
1.24 9.59e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.25 1.30e-03 GO:0030030 cell projection organization
1.18 1.47e-03 GO:0051641 cellular localization
1.30 1.64e-03 GO:0048812 neuron projection morphogenesis
1.22 1.71e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.23 1.94e-03 GO:0006468 protein phosphorylation
1.09 2.34e-03 GO:0051716 cellular response to stimulus
1.17 2.51e-03 GO:0051239 regulation of multicellular organismal process
1.25 2.54e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.41 2.74e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.19 3.39e-03 GO:0051246 regulation of protein metabolic process
1.21 3.53e-03 GO:0009891 positive regulation of biosynthetic process
1.24 3.76e-03 GO:0051254 positive regulation of RNA metabolic process
1.23 4.81e-03 GO:0045595 regulation of cell differentiation
1.10 6.12e-03 GO:0051234 establishment of localization
1.20 6.20e-03 GO:0050793 regulation of developmental process
1.31 6.52e-03 GO:0009792 embryo development ending in birth or egg hatching
1.16 7.19e-03 GO:0033036 macromolecule localization
1.21 7.24e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.27 7.48e-03 GO:0000904 cell morphogenesis involved in differentiation
1.10 8.85e-03 GO:0006810 transport
1.10 9.54e-03 GO:0007165 signal transduction
1.28 1.07e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.30 1.17e-02 GO:0043009 chordate embryonic development
1.18 1.26e-02 GO:0032268 regulation of cellular protein metabolic process
1.28 1.32e-02 GO:0007409 axonogenesis
1.26 1.33e-02 GO:0032990 cell part morphogenesis
1.31 1.42e-02 GO:0012502 induction of programmed cell death
1.26 1.42e-02 GO:0048858 cell projection morphogenesis
1.18 1.66e-02 GO:0043067 regulation of programmed cell death
1.24 1.66e-02 GO:0000902 cell morphogenesis
1.21 1.81e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 1.88e-02 GO:0006917 induction of apoptosis
1.18 1.90e-02 GO:0042981 regulation of apoptosis
1.63 1.92e-02 GO:0018205 peptidyl-lysine modification
1.17 2.12e-02 GO:0051649 establishment of localization in cell
1.20 2.33e-02 GO:0046907 intracellular transport
1.20 2.42e-02 GO:0051128 regulation of cellular component organization
1.26 2.66e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.22 2.81e-02 GO:0032989 cellular component morphogenesis
1.19 3.38e-02 GO:0033554 cellular response to stress
1.18 3.62e-02 GO:0042127 regulation of cell proliferation
1.17 3.85e-02 GO:0010941 regulation of cell death
1.12 3.89e-02 GO:0048583 regulation of response to stimulus
1.20 4.06e-02 GO:0012501 programmed cell death
1.33 4.73e-02 GO:0007346 regulation of mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 4.92e-41 GO:0005622 intracellular
1.09 2.08e-38 GO:0044424 intracellular part
1.10 7.32e-30 GO:0043226 organelle
1.11 9.03e-30 GO:0043227 membrane-bounded organelle
1.10 1.85e-29 GO:0043229 intracellular organelle
1.11 2.11e-29 GO:0043231 intracellular membrane-bounded organelle
1.11 3.08e-24 GO:0005737 cytoplasm
1.15 2.32e-22 GO:0005634 nucleus
1.11 1.33e-13 GO:0044444 cytoplasmic part
1.21 1.61e-13 GO:0044428 nuclear part
1.22 6.73e-13 GO:0031981 nuclear lumen
1.11 2.17e-12 GO:0044422 organelle part
1.03 2.26e-12 GO:0005623 cell
1.03 2.84e-12 GO:0044464 cell part
1.11 3.75e-12 GO:0044446 intracellular organelle part
1.19 4.11e-12 GO:0070013 intracellular organelle lumen
1.19 5.48e-12 GO:0043233 organelle lumen
1.19 2.02e-11 GO:0031974 membrane-enclosed lumen
1.24 4.73e-10 GO:0005654 nucleoplasm
1.32 3.12e-09 GO:0044451 nucleoplasm part
1.18 4.40e-09 GO:0005829 cytosol
1.14 7.67e-08 GO:0043234 protein complex
1.12 9.91e-07 GO:0032991 macromolecular complex
1.27 1.11e-04 GO:0005694 chromosome
1.41 1.89e-04 GO:0016323 basolateral plasma membrane
1.57 2.02e-03 GO:0005925 focal adhesion
1.54 3.66e-03 GO:0005924 cell-substrate adherens junction
1.53 3.95e-03 GO:0030055 cell-substrate junction
1.37 4.30e-03 GO:0000228 nuclear chromosome
1.11 6.18e-03 GO:0031090 organelle membrane
1.22 7.55e-03 GO:0030054 cell junction
1.25 8.35e-03 GO:0044427 chromosomal part
1.13 1.07e-02 GO:0012505 endomembrane system
1.34 1.83e-02 GO:0016604 nuclear body
1.11 1.90e-02 GO:0044459 plasma membrane part
1.38 2.11e-02 GO:0044454 nuclear chromosome part
1.63 2.21e-02 GO:0030426 growth cone
1.25 2.39e-02 GO:0045202 synapse
1.62 2.40e-02 GO:0030427 site of polarized growth
1.26 3.20e-02 GO:0048471 perinuclear region of cytoplasm
1.40 3.33e-02 GO:0005912 adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.15 6.05e-36 GO:0005515 protein binding
1.07 8.99e-23 GO:0005488 binding
1.26 3.09e-08 GO:0030528 transcription regulator activity
1.31 3.86e-08 GO:0043565 sequence-specific DNA binding
1.27 1.77e-06 GO:0019899 enzyme binding
1.35 1.80e-06 GO:0019904 protein domain specific binding
1.22 9.32e-06 GO:0001071 nucleic acid binding transcription factor activity
1.22 9.32e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.10 1.97e-04 GO:0003676 nucleic acid binding
1.23 2.46e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.13 2.82e-04 GO:0003677 DNA binding
1.35 5.31e-04 GO:0016563 transcription activator activity
1.44 5.56e-04 GO:0010843 promoter binding
1.22 8.41e-04 GO:0042802 identical protein binding
1.42 1.15e-03 GO:0000975 regulatory region DNA binding
1.42 1.15e-03 GO:0001067 regulatory region nucleic acid binding
1.42 1.15e-03 GO:0044212 transcription regulatory region DNA binding
1.12 1.55e-03 GO:0000166 nucleotide binding
1.30 1.83e-03 GO:0000988 protein binding transcription factor activity
1.30 1.83e-03 GO:0000989 transcription factor binding transcription factor activity
1.19 1.87e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.21 1.93e-03 GO:0016301 kinase activity
1.30 2.40e-03 GO:0003712 transcription cofactor activity
1.23 3.55e-03 GO:0004672 protein kinase activity
1.27 5.83e-03 GO:0004674 protein serine/threonine kinase activity
1.55 6.55e-03 GO:0005057 receptor signaling protein activity
1.13 2.15e-02 GO:0030554 adenyl nucleotide binding
1.13 2.66e-02 GO:0005524 ATP binding
1.29 2.80e-02 GO:0016564 transcription repressor activity
1.30 3.42e-02 GO:0008134 transcription factor binding
1.56 4.29e-02 GO:0031625 ubiquitin protein ligase binding