Motif ID: MZF1.p2

Z-value: 1.150


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_59084928-0.271.4e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51487070 3.792 NM_139277
NM_001207053
NM_001243126
NM_005046
 KLK7



kallikrein-related peptidase 7



chr19_-_55658310 3.448 TNNT1
troponin T type 1 (skeletal, slow)
chr14_-_23834417 2.096 EFS
embryonal Fyn-associated substrate
chr19_-_51472003 2.006 NM_001012964
NM_001012965
 KLK6

kallikrein-related peptidase 6

chr2_-_216300770 1.865 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr14_-_23834378 1.804 EFS
embryonal Fyn-associated substrate
chr6_-_30655078 1.630 NM_001134870
 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_-_51504799 1.550 NM_007196
NM_144505
NM_144506
NM_144507
 KLK8



kallikrein-related peptidase 8



chr17_+_70117177 1.526 SOX9
SRY (sex determining region Y)-box 9
chr17_+_70117154 1.471 NM_000346
 SOX9
SRY (sex determining region Y)-box 9
chr6_-_30654978 1.383 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr1_+_205473768 1.377 CDK18
cyclin-dependent kinase 18
chr11_+_5617330 1.345 NM_058166
 TRIM6
tripartite motif containing 6
chr1_-_155948206 1.317 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_205473683 1.301 NM_002596
NM_212502
NM_212503
 CDK18


cyclin-dependent kinase 18


chr7_-_149470294 1.262 NM_207336
 ZNF467
zinc finger protein 467
chr14_+_24867926 1.251 NM_025081
 NYNRIN
NYN domain and retroviral integrase containing
chr5_-_127873734 1.230 NM_001999
 FBN2
fibrillin 2
chr17_+_70117168 1.210 SOX9
SRY (sex determining region Y)-box 9
chr5_+_92918924 1.209 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 145 entries
enrichment   p-value GO term description
1.57 4.49e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.44 7.53e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.44 2.82e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.42 2.15e-03 GO:0060284 regulation of cell development
1.42 4.35e-02 GO:0030168 platelet activation
1.38 1.03e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.38 1.90e-03 GO:0007264 small GTPase mediated signal transduction
1.37 4.11e-07 GO:0051254 positive regulation of RNA metabolic process
1.37 5.08e-07 GO:0010628 positive regulation of gene expression
1.37 7.72e-04 GO:0007268 synaptic transmission
1.36 4.86e-09 GO:0048699 generation of neurons
1.36 1.99e-04 GO:0031175 neuron projection development
1.36 3.40e-04 GO:0019226 transmission of nerve impulse
1.36 3.40e-04 GO:0035637 multicellular organismal signaling
1.36 1.31e-03 GO:0051094 positive regulation of developmental process
1.36 1.96e-02 GO:0007389 pattern specification process
1.36 3.04e-02 GO:0045597 positive regulation of cell differentiation
1.36 4.19e-02 GO:0007411 axon guidance
1.35 2.25e-09 GO:0022008 neurogenesis
1.35 1.96e-06 GO:0030182 neuron differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
1.73 3.19e-03 GO:0000790 nuclear chromatin
1.70 4.63e-03 GO:0030665 clathrin coated vesicle membrane
1.57 1.40e-02 GO:0030662 coated vesicle membrane
1.52 2.20e-03 GO:0030136 clathrin-coated vesicle
1.48 1.17e-03 GO:0030135 coated vesicle
1.42 4.92e-03 GO:0016323 basolateral plasma membrane
1.40 1.15e-02 GO:0000785 chromatin
1.34 1.33e-02 GO:0044433 cytoplasmic vesicle part
1.31 8.88e-03 GO:0043005 neuron projection
1.30 1.37e-02 GO:0045202 synapse
1.29 4.18e-04 GO:0030054 cell junction
1.23 3.00e-03 GO:0031982 vesicle
1.23 4.27e-03 GO:0031410 cytoplasmic vesicle
1.23 5.53e-03 GO:0031988 membrane-bounded vesicle
1.23 8.25e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.19 3.47e-06 GO:0031981 nuclear lumen
1.19 6.27e-04 GO:0005654 nucleoplasm
1.18 1.11e-06 GO:0005829 cytosol
1.18 1.62e-06 GO:0044459 plasma membrane part
1.16 5.97e-05 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.63 1.42e-06 GO:0010843 promoter binding
1.63 1.75e-04 GO:0003714 transcription corepressor activity
1.62 9.31e-07 GO:0000975 regulatory region DNA binding
1.62 9.31e-07 GO:0001067 regulatory region nucleic acid binding
1.62 9.31e-07 GO:0044212 transcription regulatory region DNA binding
1.46 2.09e-05 GO:0016563 transcription activator activity
1.41 9.47e-04 GO:0008134 transcription factor binding
1.40 6.66e-10 GO:0043565 sequence-specific DNA binding
1.39 1.83e-05 GO:0019904 protein domain specific binding
1.37 8.22e-04 GO:0000988 protein binding transcription factor activity
1.37 8.22e-04 GO:0000989 transcription factor binding transcription factor activity
1.36 1.14e-03 GO:0003712 transcription cofactor activity
1.33 2.76e-10 GO:0030528 transcription regulator activity
1.30 3.58e-08 GO:0001071 nucleic acid binding transcription factor activity
1.30 3.58e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.30 1.75e-02 GO:0004674 protein serine/threonine kinase activity
1.25 1.74e-02 GO:0004672 protein kinase activity
1.17 4.78e-33 GO:0005515 protein binding
1.07 3.74e-19 GO:0005488 binding