Motif ID: NFATC1..3.p2

Z-value: 1.236


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC3chr16_+_68119211-0.711.1e-05Click!
NFATC1chr18_+_77155927-0.702.0e-05Click!
NFATC2chr20_-_501590370.431.8e-02Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_13349720 9.241 EMP1
epithelial membrane protein 1
chr12_+_13349601 7.468 NM_001423
 EMP1
epithelial membrane protein 1
chr1_-_205391180 7.095 NM_001001552
NM_001199050
NM_001199051
NM_001199052
 LEMD1



LEM domain containing 1



chr2_+_113885145 6.114 IL1RN
interleukin 1 receptor antagonist
chr2_+_113885137 6.050 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr1_+_171154387 4.473 NM_001460
 FMO2
flavin containing monooxygenase 2 (non-functional)
chr4_-_159093523 3.943 FAM198B
family with sequence similarity 198, member B
chr12_+_41086189 3.828 NM_001843
NM_175038
 CNTN1

contactin 1

chr2_-_216259197 3.477 FN1
fibronectin 1
chr2_+_113735595 3.450 NM_019618
 IL36G
interleukin 36, gamma
chr18_+_29027731 3.399 NM_001944
 DSG3
desmoglein 3
chr22_+_38071612 3.337 NM_002305
 LGALS1
lectin, galactoside-binding, soluble, 1
chr2_-_238322815 3.318 COL6A3
collagen, type VI, alpha 3
chr2_-_238322840 3.273 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr8_-_125580745 3.052 MTSS1
metastasis suppressor 1
chr2_-_238322770 3.006 COL6A3
collagen, type VI, alpha 3
chr8_-_7274353 2.789 NM_001205266
 DEFB4B
defensin, beta 4B
chr19_+_35645640 2.722 NM_144779
NM_001164605
 FXYD5

FXYD domain containing ion transport regulator 5

chr10_+_118187381 2.720 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr2_-_31637598 2.577 NM_000379
 XDH
xanthine dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
2.04 1.47e-02 GO:0034330 cell junction organization
1.91 9.41e-10 GO:0007599 hemostasis
1.91 1.15e-03 GO:0030168 platelet activation
1.89 3.07e-09 GO:0007596 blood coagulation
1.89 3.07e-09 GO:0050817 coagulation
1.80 1.26e-02 GO:0045321 leukocyte activation
1.79 5.90e-09 GO:0042060 wound healing
1.79 4.22e-07 GO:0001775 cell activation
1.78 3.53e-08 GO:0050878 regulation of body fluid levels
1.75 3.77e-13 GO:0009611 response to wounding
1.74 1.18e-02 GO:0006954 inflammatory response
1.57 3.07e-03 GO:0008284 positive regulation of cell proliferation
1.51 1.21e-04 GO:0006952 defense response
1.49 8.95e-04 GO:0007267 cell-cell signaling
1.49 1.26e-03 GO:0007155 cell adhesion
1.49 1.26e-03 GO:0022610 biological adhesion
1.47 1.03e-06 GO:0002376 immune system process
1.45 9.97e-04 GO:0051704 multi-organism process
1.43 1.91e-02 GO:0006955 immune response
1.37 1.52e-02 GO:0007154 cell communication

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.70 2.57e-03 GO:0031091 platelet alpha granule
2.68 2.08e-02 GO:0031093 platelet alpha granule lumen
2.63 2.88e-02 GO:0034774 secretory granule lumen
2.56 2.74e-02 GO:0031983 vesicle lumen
1.76 3.26e-04 GO:0015629 actin cytoskeleton
1.49 4.89e-05 GO:0005615 extracellular space
1.48 6.16e-07 GO:0044421 extracellular region part
1.41 4.93e-11 GO:0005576 extracellular region
1.28 3.16e-05 GO:0044459 plasma membrane part
1.27 3.94e-02 GO:0031226 intrinsic to plasma membrane
1.27 4.61e-02 GO:0005887 integral to plasma membrane
1.18 4.43e-05 GO:0005886 plasma membrane
1.18 6.62e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.88 7.88e-04 GO:0033293 monocarboxylic acid binding
1.63 1.09e-02 GO:0003779 actin binding
1.44 4.29e-02 GO:0008092 cytoskeletal protein binding
1.31 4.36e-02 GO:0005102 receptor binding
1.11 5.53e-04 GO:0005515 protein binding