• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NFATC1..3.p2

Z-value: 1.236

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_13349720	9.241		EMP1	epithelial membrane protein 1
chr12_+_13349601	7.468	NM_001423	EMP1	epithelial membrane protein 1
chr1_-_205391180	7.095	NM_001001552 NM_001199050 NM_001199051 NM_001199052	LEMD1	LEM domain containing 1
chr2_+_113885145	6.114		IL1RN	interleukin 1 receptor antagonist
chr2_+_113885137	6.050	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr1_+_171154387	4.473	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr4_-_159093523	3.943		FAM198B	family with sequence similarity 198, member B
chr12_+_41086189	3.828	NM_001843 NM_175038	CNTN1	contactin 1
chr2_-_216259197	3.477		FN1	fibronectin 1
chr2_+_113735595	3.450	NM_019618	IL36G	interleukin 36, gamma
chr18_+_29027731	3.399	NM_001944	DSG3	desmoglein 3
chr22_+_38071612	3.337	NM_002305	LGALS1	lectin, galactoside-binding, soluble, 1
chr2_-_238322815	3.318		COL6A3	collagen, type VI, alpha 3
chr2_-_238322840	3.273	NM_004369 NM_057164 NM_057165 NM_057166 NM_057167	COL6A3	collagen, type VI, alpha 3
chr8_-_125580745	3.052		MTSS1	metastasis suppressor 1
chr2_-_238322770	3.006		COL6A3	collagen, type VI, alpha 3
chr8_-_7274353	2.789	NM_001205266	DEFB4B	defensin, beta 4B
chr19_+_35645640	2.722	NM_144779 NM_001164605	FXYD5	FXYD domain containing ion transport regulator 5
chr10_+_118187381	2.720	NM_001011709	PNLIPRP3	pancreatic lipase-related protein 3
chr2_-_31637598	2.577	NM_000379	XDH	xanthine dehydrogenase
chr1_-_169599349	2.456	NM_003005	SELP	selectin P (granule membrane protein 140kDa, antigen CD62)
chr17_-_38859976	2.438	NM_019016	KRT24	keratin 24
chr15_-_80263460	2.428	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr22_+_31478845	2.342	NM_001207017	SMTN	smoothelin
chr1_+_24645914	2.339	NM_001195010	GRHL3	grainyhead-like 3 (Drosophila)
chr18_-_28681885	2.332	NM_004949 NM_024422	DSC2	desmocollin 2
chr19_-_14887623	2.323		EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr14_-_75422466	2.311	NM_001207012 NM_002632	PGF	placental growth factor
chr12_+_8975149	2.278	NM_144670	A2ML1	alpha-2-macroglobulin-like 1
chr6_+_106546736	2.194	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr19_+_7049349	2.162	NM_144614	MBD3L2	methyl-CpG binding domain protein 3-like 2
chr1_+_24645811	2.127	NM_198173 NM_198174	GRHL3	grainyhead-like 3 (Drosophila)
chr12_+_13349716	2.112		EMP1	epithelial membrane protein 1
chr19_-_51472003	2.088	NM_001012964 NM_001012965	KLK6	kallikrein-related peptidase 6
chr6_-_131384387	2.048	NM_001135554 NM_001135555 NM_001199388 NM_001431	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chrX_+_135251454	1.989	NM_001159704	FHL1	four and a half LIM domains 1
chr12_+_119616594	1.967	NM_014365	HSPB8	heat shock 22kDa protein 8
chr4_+_71200670	1.963	NM_033122	CABS1	calcium-binding protein, spermatid-specific 1
chr15_+_63481788	1.941		RAB8B	RAB8B, member RAS oncogene family
chr6_+_47666288	1.932	NM_153838	GPR115	G protein-coupled receptor 115
chr19_-_41859830	1.926	NM_000660	TGFB1	transforming growth factor, beta 1
chrX_+_100805415	1.912	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr13_+_111134933	1.870		COL4A2	collagen, type IV, alpha 2
chr2_-_127963342	1.838	NM_001001665	CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1
chr12_-_91505215	1.838		LUM	lumican
chr6_-_30655671	1.804	NM_133471	PPP1R18	protein phosphatase 1, regulatory subunit 18
chr9_-_36276930	1.802	NM_001128227 NM_001190388	GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr4_+_71248794	1.783	NM_006685	SMR3B	submaxillary gland androgen regulated protein 3B
chr20_+_33759773	1.777	NM_006404	PROCR	protein C receptor, endothelial
chr18_-_28681429	1.723		DSC2	desmocollin 2
chr6_-_131384321	1.673		EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr6_-_112080284	1.646	NM_153048	FYN	FYN oncogene related to SRC, FGR, YES
chr8_+_7752198	1.643	NM_004942	DEFB4A	defensin, beta 4A
chr1_-_150780705	1.620	NM_000396	CTSK	cathepsin K
chr12_-_91505541	1.618	NM_002345	LUM	lumican
chr7_+_18535351	1.608	NM_001204145 NM_001204146 NM_014707 NM_178423	HDAC9	histone deacetylase 9
chrX_+_135229536	1.608	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr2_+_102953716	1.567	NM_003856	IL1RL1	interleukin 1 receptor-like 1
chr2_-_31637553	1.554		XDH	xanthine dehydrogenase
chr4_-_159093717	1.548	NM_016613	FAM198B	family with sequence similarity 198, member B
chr19_-_43269818	1.512	NM_001130167 NM_001130168 NM_182707	PSG8	pregnancy specific beta-1-glycoprotein 8
chr2_-_216241321	1.511		FN1	fibronectin 1
chr9_+_706744	1.502	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr7_+_134233848	1.475	NM_001080538	AKR1B15	aldo-keto reductase family 1, member B15
chr7_-_41742666	1.475	NM_002192	INHBA	inhibin, beta A
chr8_-_15095791	1.474	NM_139167	SGCZ	sarcoglycan, zeta
chr17_-_8113862	1.467	NM_004217	AURKB	aurora kinase B
chr13_-_24007822	1.450	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr4_-_103998169	1.431	NM_178833	SLC9B2	solute carrier family 9, subfamily B (cation proton antiporter 2), member 2
chr9_-_35689902	1.419	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chr19_+_11200037	1.402	NM_000527 NM_001195798 NM_001195799 NM_001195800 NM_001195802 NM_001195803	LDLR	low density lipoprotein receptor
chr18_+_61420276	1.382	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr21_+_39628869	1.358	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr5_+_96211643	1.336	NM_001130140 NM_022350	ERAP2	endoplasmic reticulum aminopeptidase 2
chr5_+_137514753	1.336		KIF20A	kinesin family member 20A
chr10_+_91498724	1.331		KIF20B	kinesin family member 20B
chr14_+_54863672	1.330	NM_001130851 NM_005192	CDKN3	cyclin-dependent kinase inhibitor 3
chr2_+_11886739	1.324	NM_145693	LPIN1	lipin 1
chr12_+_107974633	1.306	NM_001017523	BTBD11	BTB (POZ) domain containing 11
chr4_+_41258909	1.298		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr22_+_33196801	1.291	NM_000362	TIMP3	TIMP metallopeptidase inhibitor 3
chr22_-_36236264	1.281		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr4_+_41258895	1.274	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_-_76928601	1.271	NM_002416	CXCL9	chemokine (C-X-C motif) ligand 9
chr9_+_75136716	1.257	NM_138691	TMC1	transmembrane channel-like 1
chr7_+_80267782	1.256	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr9_-_74675498	1.253	NM_001128618	C9orf57	chromosome 9 open reading frame 57
chr4_-_71532341	1.247	NM_144646	IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chrX_+_2670092	1.240	NM_001141919 NM_001141920 NM_175569	XGPY2 XG	Xg pseudogene, Y-linked 2 Xg blood group
chr8_+_80523376	1.238		STMN2	stathmin-like 2
chr4_-_57547845	1.237	NM_001145460 NM_032495 NM_139212	HOPX	HOP homeobox
chr4_+_88896868	1.232		SPP1	secreted phosphoprotein 1
chr1_+_84630014	1.228	NM_001242857 NM_001242858 NM_001242859	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_-_231560789	1.227	NM_022051	EGLN1	egl nine homolog 1 (C. elegans)
chr3_-_50336662	1.222	NM_001200016 NM_012191 NM_001200030 NM_001200031 NM_001200032 NM_003549	NAT6 HYAL3	N-acetyltransferase 6 (GCN5-related) hyaluronoglucosaminidase 3
chr2_-_190044330	1.221	NM_000393	COL5A2	collagen, type V, alpha 2
chr11_-_5537815	1.213	NM_145053	UBQLNL	ubiquilin-like
chr2_-_215896809	1.209	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr1_-_47655723	1.209	NM_005764	PDZK1IP1	PDZK1 interacting protein 1
chr7_-_100860991	1.203	NM_001084	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chrX_-_107682600	1.198	NM_001847	COL4A6	collagen, type IV, alpha 6
chr6_-_131291480	1.194	NM_001199389	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr13_+_109281569	1.188	NM_001198950	MYO16	myosin XVI
chr1_-_155948934	1.186		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr13_-_60325073	1.184
chr4_+_88896838	1.180		SPP1	secreted phosphoprotein 1
chr1_+_86889768	1.168	NM_006536	CLCA2	chloride channel accessory 2
chr3_+_121902529	1.167	NM_000388	CASR	calcium-sensing receptor
chr16_+_82660390	1.162	NM_001220488 NM_001220489 NM_001220490 NM_001220491 NM_001220492 NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr1_-_47655603	1.147		PDZK1IP1	PDZK1 interacting protein 1
chr11_+_125495030	1.142	NM_001114121 NM_001114122 NM_001244846	CHEK1	checkpoint kinase 1
chr4_+_156680125	1.141	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr2_+_75059781	1.140	NM_000189	HK2	hexokinase 2
chr17_-_17740309	1.121	NM_001005291 NM_004176	SREBF1	sterol regulatory element binding transcription factor 1
chr2_+_113875469	1.107	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr5_+_161277702	1.105	NM_001127648	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_+_88896899	1.102		SPP1	secreted phosphoprotein 1
chr4_-_103266577	1.098	NM_001135146	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr12_-_10955168	1.097	NM_023919	TAS2R7	taste receptor, type 2, member 7
chr4_+_41258941	1.094		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr1_+_40627066	1.093		RLF	rearranged L-myc fusion
chr14_+_65171243	1.045		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_-_6580068	1.042	NM_198681	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_-_35992798	1.039	NM_001035516	DMKN	dermokine
chr5_-_150537335	1.038	NM_001155	ANXA6	annexin A6
chr18_+_21269404	1.032		LAMA3	laminin, alpha 3
chr9_-_35689799	1.032		TPM2	tropomyosin 2 (beta)
chr12_-_11244828	1.032	NM_176884	TAS2R43 TAS2R31	taste receptor, type 2, member 43 taste receptor, type 2, member 31
chr17_-_39211462	1.030	NM_033032	KRTAP2-2	keratin associated protein 2-2
chrX_-_48815641	1.027	NM_001136159	OTUD5	OTU domain containing 5
chr3_-_111314181	1.026	NM_024508	ZBED2	zinc finger, BED-type containing 2
chr1_-_161193375	1.022	NM_001643	APOA2	apolipoprotein A-II
chr22_-_36236421	1.017	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_48815582	1.017		OTUD5	OTU domain containing 5
chr4_+_95376396	1.016		PDLIM5	PDZ and LIM domain 5
chr11_-_65382701	1.012		MAP3K11	mitogen-activated protein kinase kinase kinase 11
chr21_+_39628663	1.010	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_52585686	1.010	NM_001081492 NM_182507	KRT80	keratin 80
chr7_+_26403944	1.010	NM_001199838	SNX10	sorting nexin 10
chr6_+_116782555	1.009	NM_001010919	FAM26F	family with sequence similarity 26, member F
chr2_-_134326030	1.005	NM_207363 NM_207481	NCKAP5	NCK-associated protein 5
chr12_-_28124915	0.997	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr5_-_147211141	0.996		SPINK1	serine peptidase inhibitor, Kazal type 1
chr7_+_123565908	0.985	NM_001174045 NM_001174046	SPAM1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
chrX_-_153599719	0.981		FLNA	filamin A, alpha
chr12_-_11286842	0.981	NM_001097643	TAS2R30	taste receptor, type 2, member 30
chr2_-_85637486	0.976	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr7_+_93551015	0.975	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr1_-_161193190	0.971		APOA2	apolipoprotein A-II
chr14_-_68162419	0.970	NM_001252650 NM_016026	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr7_+_116164838	0.968	NM_001753	CAV1	caveolin 1, caveolae protein, 22kDa
chrX_+_107288199	0.961	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr17_+_38444130	0.961		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_+_116654375	0.961	NM_152367	MAB21L3	mab-21-like 3 (C. elegans)
chr8_+_70405080	0.956		SULF1	sulfatase 1
chr16_+_82660573	0.956		CDH13	cadherin 13, H-cadherin (heart)
chr8_+_80523339	0.956		STMN2	stathmin-like 2
chr1_+_15802595	0.954	NM_015849	CELA2B	chymotrypsin-like elastase family, member 2B
chr6_+_106534210	0.954		PRDM1	PR domain containing 1, with ZNF domain
chr17_+_47287588	0.951	NM_001135186 NM_016428	ABI3	ABI family, member 3
chr15_+_71839540	0.950		THSD4	thrombospondin, type I, domain containing 4
chr9_-_21202201	0.948	NM_021057	IFNA7	interferon, alpha 7
chr14_+_78227172	0.947	NM_001173978 NM_174943	C14orf178	chromosome 14 open reading frame 178
chr13_-_52980628	0.945	NM_018676 NM_199263	THSD1	thrombospondin, type I, domain containing 1
chr2_-_211168315	0.945	NM_079422	MYL1	myosin, light chain 1, alkali; skeletal, fast
chr19_+_41725098	0.945	NM_001699 NM_021913	AXL	AXL receptor tyrosine kinase
chr4_-_159094163	0.940	NM_001031700 NM_001128424	FAM198B	family with sequence similarity 198, member B
chr10_-_121296044	0.940	NM_002925	RGS10	regulator of G-protein signaling 10
chr1_-_24469571	0.939	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr9_+_34989637	0.938	NM_001135004 NM_012266	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5
chr20_-_30000640	0.937	NM_001171832	DEFB121	defensin, beta 121
chr5_-_172755418	0.935		STC2	stanniocalcin 2
chr4_-_71532206	0.933		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_-_152552962	0.930	NM_032563	LCE3D	late cornified envelope 3D
chr19_-_41859253	0.930		TGFB1	transforming growth factor, beta 1
chr1_-_93342706	0.925	NM_001252271	FAM69A	family with sequence similarity 69, member A
chr2_-_85637473	0.918		CAPG	capping protein (actin filament), gelsolin-like
chr12_+_4382882	0.914	NM_001759	CCND2	cyclin D2
chr1_-_94703252	0.913	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr19_+_42212612	0.912		CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5
chr1_-_221910801	0.910	NM_144728	DUSP10	dual specificity phosphatase 10
chr7_+_80267922	0.904		CD36	CD36 molecule (thrombospondin receptor)
chr7_+_80267972	0.904		CD36	CD36 molecule (thrombospondin receptor)
chrY_-_2655478	0.894	NM_003140	SRY	sex determining region Y
chr3_-_50340979	0.889	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr5_+_92918924	0.886	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr3_+_101546833	0.881	NM_001005474	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr7_+_28452143	0.880	NM_182898	CREB5	cAMP responsive element binding protein 5
chr17_+_38444151	0.875		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_+_87012758	0.874	NM_012128	CLCA4	chloride channel accessory 4
chr3_-_178984789	0.872	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr22_-_36236330	0.869		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr5_-_147211235	0.862	NM_003122	SPINK1	serine peptidase inhibitor, Kazal type 1
chr3_-_172858959	0.859	NM_031955	SPATA16	spermatogenesis associated 16
chr6_+_34204576	0.858	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr1_-_149908759	0.857	NM_001145862	MTMR11	myotubularin related protein 11
chr19_+_11200146	0.855		LDLR	low density lipoprotein receptor
chr1_+_179560747	0.851	NM_001199091 NM_001199085 NM_173533	TDRD5	tudor domain containing 5
chr17_-_39092714	0.847		KRT23	keratin 23 (histone deacetylase inducible)
chr19_-_43709692	0.846	NM_002780 NM_213633	PSG4	pregnancy specific beta-1-glycoprotein 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.75	3.77e-13	GO:0009611	response to wounding
1.20	7.93e-11	GO:0050896	response to stimulus
1.91	9.41e-10	GO:0007599	hemostasis
1.28	1.90e-09	GO:0023052	signaling
1.36	2.42e-09	GO:0006950	response to stress
1.89	3.07e-09	GO:0007596	blood coagulation
1.89	3.07e-09	GO:0050817	coagulation
1.79	5.90e-09	GO:0042060	wound healing
1.29	7.84e-09	GO:0007165	signal transduction
1.25	8.08e-09	GO:0051716	cellular response to stimulus
1.78	3.53e-08	GO:0050878	regulation of body fluid levels
1.14	1.74e-07	GO:0065007	biological regulation
1.79	4.22e-07	GO:0001775	cell activation
1.47	1.03e-06	GO:0002376	immune system process
1.36	4.72e-06	GO:0007166	cell surface receptor linked signaling pathway
1.30	6.02e-05	GO:0065008	regulation of biological quality
1.17	7.40e-05	GO:0032501	multicellular organismal process
1.13	8.25e-05	GO:0050789	regulation of biological process
1.51	1.21e-04	GO:0006952	defense response
1.12	7.13e-04	GO:0050794	regulation of cellular process
1.49	8.95e-04	GO:0007267	cell-cell signaling
1.45	9.97e-04	GO:0051704	multi-organism process
1.91	1.15e-03	GO:0030168	platelet activation
1.49	1.26e-03	GO:0007155	cell adhesion
1.49	1.26e-03	GO:0022610	biological adhesion
1.57	3.07e-03	GO:0008284	positive regulation of cell proliferation
1.74	1.18e-02	GO:0006954	inflammatory response
1.80	1.26e-02	GO:0045321	leukocyte activation
2.04	1.47e-02	GO:0034330	cell junction organization
1.37	1.52e-02	GO:0007154	cell communication
1.43	1.91e-02	GO:0006955	immune response
1.37	3.09e-02	GO:0042127	regulation of cell proliferation
1.25	4.04e-02	GO:0048583	regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.41	4.93e-11	GO:0005576	extracellular region
1.48	6.16e-07	GO:0044421	extracellular region part
1.28	3.16e-05	GO:0044459	plasma membrane part
1.18	4.43e-05	GO:0005886	plasma membrane
1.49	4.89e-05	GO:0005615	extracellular space
1.18	6.62e-05	GO:0071944	cell periphery
1.76	3.26e-04	GO:0015629	actin cytoskeleton
2.70	2.57e-03	GO:0031091	platelet alpha granule
2.68	2.08e-02	GO:0031093	platelet alpha granule lumen
2.56	2.74e-02	GO:0031983	vesicle lumen
2.63	2.88e-02	GO:0034774	secretory granule lumen
1.27	3.94e-02	GO:0031226	intrinsic to plasma membrane
1.27	4.61e-02	GO:0005887	integral to plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	5.53e-04	GO:0005515	protein binding
2.88	7.88e-04	GO:0033293	monocarboxylic acid binding
1.63	1.09e-02	GO:0003779	actin binding
1.44	4.29e-02	GO:0008092	cytoskeletal protein binding
1.31	4.36e-02	GO:0005102	receptor binding