Motif ID: NFE2L1.p2

Z-value: 1.665


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L1chr17_+_461257250.144.7e-01Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_36019194 11.986 NM_001166034
NM_001166035
NM_198538
 SBSN


suprabasin


chr2_+_201473942 5.516 AOX1
aldehyde oxidase 1
chr16_+_82660390 5.381 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
 CDH13





cadherin 13, H-cadherin (heart)





chr2_-_161056573 5.337 NM_000888
 ITGB6
integrin, beta 6
chr2_-_216259197 5.040 FN1
fibronectin 1
chr20_-_23030141 4.862 NM_000361
 THBD
thrombomodulin
chr17_-_38859976 4.757 NM_019016
 KRT24
keratin 24
chr1_-_205391180 4.496 NM_001001552
NM_001199050
NM_001199051
NM_001199052
 LEMD1



LEM domain containing 1



chr10_+_5566923 4.128 NM_005185
 CALML3
calmodulin-like 3
chr13_-_60325073 4.093


chr16_+_82660573 4.068 CDH13
cadherin 13, H-cadherin (heart)
chr14_-_94423766 4.035 NM_016150
 ASB2
ankyrin repeat and SOCS box containing 2
chr4_-_139163222 3.905 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr12_-_123187842 3.886 NM_177551
 HCAR2
hydroxycarboxylic acid receptor 2
chr4_+_169013687 3.770 NM_007193
 ANXA10
annexin A10
chr1_+_32050510 3.659 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr12_-_123201319 3.570 NM_006018
 HCAR3
hydroxycarboxylic acid receptor 3
chr11_+_61595633 3.472 NM_004265
 FADS2
fatty acid desaturase 2
chr2_+_210444364 3.399 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr7_+_5632435 3.306 NM_003088
 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
1.61 4.47e-03 GO:0044057 regulation of system process
1.58 3.00e-06 GO:0042060 wound healing
1.55 2.83e-05 GO:0050878 regulation of body fluid levels
1.55 4.08e-04 GO:0019226 transmission of nerve impulse
1.55 4.08e-04 GO:0035637 multicellular organismal signaling
1.54 4.67e-04 GO:0007596 blood coagulation
1.54 4.67e-04 GO:0050817 coagulation
1.54 2.15e-03 GO:0007268 synaptic transmission
1.53 7.01e-04 GO:0007599 hemostasis
1.51 3.58e-08 GO:0009611 response to wounding
1.48 2.02e-05 GO:0007267 cell-cell signaling
1.46 2.39e-03 GO:0009887 organ morphogenesis
1.44 1.90e-06 GO:0007154 cell communication
1.40 1.45e-02 GO:0042325 regulation of phosphorylation
1.39 3.63e-02 GO:0001932 regulation of protein phosphorylation
1.37 8.08e-03 GO:0031399 regulation of protein modification process
1.37 3.39e-02 GO:0019220 regulation of phosphate metabolic process
1.37 3.39e-02 GO:0051174 regulation of phosphorus metabolic process
1.37 4.63e-02 GO:0009719 response to endogenous stimulus
1.36 9.13e-03 GO:0055085 transmembrane transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.07 3.05e-04 GO:0030016 myofibril
2.06 2.71e-03 GO:0030017 sarcomere
2.04 2.73e-04 GO:0043292 contractile fiber
1.98 2.74e-03 GO:0044449 contractile fiber part
1.83 5.62e-04 GO:0030424 axon
1.79 1.24e-06 GO:0015629 actin cytoskeleton
1.75 7.92e-03 GO:0070161 anchoring junction
1.72 3.93e-02 GO:0005912 adherens junction
1.48 6.66e-03 GO:0043005 neuron projection
1.39 1.40e-04 GO:0005626 insoluble fraction
1.35 1.66e-03 GO:0005624 membrane fraction
1.32 3.97e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.31 1.16e-03 GO:0044430 cytoskeletal part
1.30 1.51e-05 GO:0005856 cytoskeleton
1.30 3.97e-02 GO:0031410 cytoplasmic vesicle
1.29 3.65e-03 GO:0000267 cell fraction
1.29 2.71e-02 GO:0042995 cell projection
1.23 7.05e-05 GO:0044459 plasma membrane part
1.20 1.53e-04 GO:0043228 non-membrane-bounded organelle
1.20 1.53e-04 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.12 5.69e-03 GO:0008066 glutamate receptor activity
2.46 2.23e-04 GO:0005200 structural constituent of cytoskeleton
1.66 2.67e-02 GO:0015291 secondary active transmembrane transporter activity
1.63 3.70e-04 GO:0003779 actin binding
1.52 4.09e-05 GO:0008092 cytoskeletal protein binding
1.45 5.19e-04 GO:0005198 structural molecule activity
1.35 8.95e-03 GO:0015075 ion transmembrane transporter activity
1.34 2.62e-03 GO:0022891 substrate-specific transmembrane transporter activity
1.31 7.59e-03 GO:0022857 transmembrane transporter activity
1.13 1.15e-08 GO:0005515 protein binding