Motif ID: NFE2L2.p2

Z-value: 0.721


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_1781298580.412.3e-02Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_34397786 3.327 NM_032596
 C9orf24
chromosome 9 open reading frame 24
chr7_+_23286384 1.886 GPNMB
glycoprotein (transmembrane) nmb
chr12_+_56075329 1.799 NM_152637
 METTL7B
methyltransferase like 7B
chr7_+_37960418 1.772 EPDR1
ependymin related protein 1 (zebrafish)
chr12_+_56075418 1.688 METTL7B
methyltransferase like 7B
chr7_+_23286277 1.677 NM_001005340
NM_002510
 GPNMB

glycoprotein (transmembrane) nmb

chr7_+_37960920 1.645 NM_001242948
 EPDR1
ependymin related protein 1 (zebrafish)
chr4_-_16077740 1.612 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
 PROM1




prominin 1




chr19_+_50706868 1.509 NM_001077186
NM_001145809
NM_024729
 MYH14


myosin, heavy chain 14, non-muscle


chr7_+_23286386 1.488 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_162838550 1.429 NM_178550
 C1orf110
chromosome 1 open reading frame 110
chr7_+_23286390 1.241 GPNMB
glycoprotein (transmembrane) nmb
chr14_-_21572374 1.224


chr16_+_80574853 1.145 NM_130897
 DYNLRB2
dynein, light chain, roadblock-type 2
chr5_-_35938736 1.132 NM_001042625
NM_144647
 CAPSL

calcyphosine-like

chr9_+_140135738 1.130 TUBB4B
tubulin, beta 4B class IVb
chr10_+_114136014 1.111 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_+_2083264 1.107 NM_001252073
NM_001252075
NM_001252076
 SLC9A3R2


solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2


chr19_+_56347943 1.082 NM_134444
 NLRP4
NLR family, pyrin domain containing 4
chr9_+_139921915 1.045 NM_207511
 C9orf139
chromosome 9 open reading frame 139

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
6.58 2.69e-05 GO:0006521 regulation of cellular amino acid metabolic process
6.13 2.38e-05 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.13 2.38e-05 GO:0072395 signal transduction involved in cell cycle checkpoint
6.13 2.38e-05 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.13 2.38e-05 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.13 2.38e-05 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.13 2.38e-05 GO:0072422 signal transduction involved in DNA damage checkpoint
6.13 2.38e-05 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.13 2.38e-05 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
5.86 1.56e-05 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
5.84 4.82e-05 GO:0071158 positive regulation of cell cycle arrest
5.61 3.03e-05 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.61 4.35e-02 GO:0051899 membrane depolarization
5.47 6.05e-06 GO:0051351 positive regulation of ligase activity
5.45 3.55e-04 GO:0033238 regulation of cellular amine metabolic process
5.43 1.85e-05 GO:0051443 positive regulation of ubiquitin-protein ligase activity
5.21 6.49e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.18 1.03e-04 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.17 4.12e-05 GO:2000045 regulation of G1/S transition of mitotic cell cycle
5.11 1.25e-04 GO:0031575 mitotic cell cycle G1/S transition checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
6.72 8.67e-08 GO:0000502 proteasome complex
1.41 4.21e-02 GO:0005829 cytosol
1.16 2.38e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.19 1.38e-02 GO:0030246 carbohydrate binding