Motif ID: NFKB1_REL_RELA.p2

Z-value: 2.149


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RELAchr11_-_654304270.613.5e-04Click!
RELchr2_+_611087020.422.2e-02Click!
NFKB1chr4_+_103422822,
chr4_+_103422553
0.115.6e-01Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_47655603 6.631 PDZK1IP1
PDZK1 interacting protein 1
chr1_-_47655723 6.366 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr12_-_76425375 5.708 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr2_+_228678556 5.271 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr12_-_76425207 4.926 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr19_-_41859332 4.333 TGFB1
transforming growth factor, beta 1
chr19_-_41859830 4.066 NM_000660
TGFB1
transforming growth factor, beta 1
chr4_-_74864296 3.933 NM_002994
CXCL5
chemokine (C-X-C motif) ligand 5
chr19_-_41859519 3.694 TGFB1
transforming growth factor, beta 1
chr12_+_53491448 3.502 IGFBP6
insulin-like growth factor binding protein 6
chr12_+_53491417 3.501 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr13_-_20806533 3.345 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr22_-_37640187 3.147 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640287 3.031 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr9_+_131183225 2.994 CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_41859253 2.990 TGFB1
transforming growth factor, beta 1
chr9_-_136344182 2.966 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr12_-_54813002 2.932 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr15_-_75017710 2.910 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr2_+_113993082 2.883 LOC654433
uncharacterized LOC654433
chr7_+_18548899 2.841 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr19_+_41725098 2.801 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr10_+_104154228 2.712 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr11_+_43963809 2.679 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr17_+_74381186 2.488 NM_001142602
SPHK1
sphingosine kinase 1
chr16_+_3115611 2.484 NM_001012635
IL32
interleukin 32
chr12_-_54812936 2.476 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr2_+_233925104 2.404 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr12_-_91505215 2.374 LUM
lumican
chr20_-_749127 2.374 NM_033409
C20orf54
chromosome 20 open reading frame 54
chr2_-_31361591 2.357 NM_001253826
NM_024572
GALNT14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)

chr16_+_3115312 2.356 NM_001012631
NM_001012633
NM_001012718
NM_004221
IL32



interleukin 32



chr5_-_136834887 2.349 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr3_-_48632592 2.328 NM_000094
COL7A1
collagen, type VII, alpha 1
chr7_-_102920665 2.327 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr19_+_54371125 2.309 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr16_+_3115638 2.308 NM_001012634
IL32
interleukin 32
chr18_-_28681429 2.297 DSC2
desmocollin 2
chr17_+_65373362 2.290 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_+_36726883 2.284 ZNF146
zinc finger protein 146
chr19_+_54371150 2.277 MYADM
myeloid-associated differentiation marker
chr6_+_130339715 2.249 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr2_-_235405692 2.249 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr17_+_74381419 2.231 SPHK1
sphingosine kinase 1
chr1_-_209825797 2.226 NM_000228
LAMB3
laminin, beta 3
chr11_+_102188180 2.211 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr19_+_54371170 2.201 MYADM
myeloid-associated differentiation marker
chr17_+_65373574 2.162 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_37940180 2.157 ZC3H12A
zinc finger CCCH-type containing 12A
chr2_+_64681610 2.140 LGALSL
lectin, galactoside-binding-like
chr2_-_74669005 2.127 RTKN
rhotekin
chr12_-_49259549 2.123 NM_014470
RND1
Rho family GTPase 1
chr16_+_3115639 2.099 IL32
interleukin 32
chr7_+_134464161 2.094 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr13_+_96204941 2.086 NM_006984
CLDN10
claudin 10
chr10_+_104155431 2.077 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr12_-_54813010 2.054 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr7_+_134464417 2.052 CALD1
caldesmon 1
chr2_+_233925035 2.048 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr2_-_31361284 2.031 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr19_-_51456159 2.002 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr2_+_95691428 1.978 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr20_+_43803539 1.972 NM_002638
PI3
peptidase inhibitor 3, skin-derived
chr7_-_24797031 1.941 DFNA5
deafness, autosomal dominant 5
chr8_-_23261591 1.938 LOXL2
lysyl oxidase-like 2
chr1_-_186649421 1.896 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_209824641 1.885 NM_001017402
LAMB3
laminin, beta 3
chr6_+_106534188 1.881 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr19_-_51522953 1.858 NM_145888
KLK10
kallikrein-related peptidase 10
chr4_-_74964996 1.804 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr7_+_100797685 1.797 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr6_-_2903461 1.793 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr1_-_38100575 1.788 NM_001038633
NM_001242908
NM_001242909
NM_001242910
RSPO1



R-spondin 1



chr4_-_74904329 1.758 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr12_+_88429245 1.758 NM_001009894
C12orf29
chromosome 12 open reading frame 29
chr18_+_33877630 1.747 NM_025135
FHOD3
formin homology 2 domain containing 3
chr9_+_131182690 1.715 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr2_-_74669026 1.694 RTKN
rhotekin
chr4_+_156680125 1.685 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr7_+_107301079 1.638 NM_000441
SLC26A4
solute carrier family 26, member 4
chr1_-_38100287 1.631 RSPO1
R-spondin 1
chr19_-_4831711 1.622 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr6_-_30523933 1.621 GNL1
guanine nucleotide binding protein-like 1
chr11_+_18287807 1.612 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr10_+_102756829 1.601 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr9_+_131183122 1.599 CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_1513187 1.595 NM_213604
ADAMTSL5
ADAMTS-like 5
chr19_-_11688441 1.585 ACP5
acid phosphatase 5, tartrate resistant
chr12_-_113909876 1.574 NM_022363
LHX5
LIM homeobox 5
chrX_+_64887593 1.573 MSN
moesin
chr7_+_143013218 1.564 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr14_-_35873823 1.546 NM_020529
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr1_+_150480486 1.537 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr17_+_40610940 1.529 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr1_+_203596222 1.527 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chrX_+_64887534 1.523 MSN
moesin
chr12_+_110011499 1.513 NM_000431
NM_001114185
MVK

mevalonate kinase

chr5_-_171615239 1.512 STK10
serine/threonine kinase 10
chr1_-_154943001 1.501 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr3_-_195306274 1.492 APOD
apolipoprotein D
chr20_-_23030141 1.474 NM_000361
THBD
thrombomodulin
chrX_+_135229536 1.458 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr1_+_45266035 1.456 NM_004073
PLK3
polo-like kinase 3
chr1_+_111770280 1.438 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr17_+_40610897 1.432 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr2_+_113735595 1.424 NM_019618
IL36G
interleukin 36, gamma
chr19_-_41859767 1.414 TGFB1
transforming growth factor, beta 1
chrX_+_64887510 1.414 NM_002444
MSN
moesin
chr2_-_74669055 1.404 NM_001015055
RTKN
rhotekin
chr1_+_203595897 1.400 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr10_-_3827205 1.399 KLF6
Kruppel-like factor 6
chr5_-_171615095 1.379 STK10
serine/threonine kinase 10
chr10_+_94833646 1.359 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr4_+_142557722 1.356 NM_000585
NM_172175
IL15

interleukin 15

chr20_+_44637539 1.354 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr7_+_134464372 1.348 CALD1
caldesmon 1
chr3_-_52090090 1.334 NM_001947
DUSP7
dual specificity phosphatase 7
chr19_+_2096930 1.323 IZUMO4
IZUMO family member 4
chr4_-_76944585 1.322 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr17_+_12569206 1.313 NM_001146312
NM_153604
MYOCD

myocardin

chr1_+_211432726 1.312 RCOR3
REST corepressor 3
chr6_+_36646455 1.309 NM_000389
NM_001220778
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr12_-_52585686 1.308 NM_001081492
NM_182507
KRT80

keratin 80

chr20_-_50179167 1.303 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr1_+_211432732 1.303 RCOR3
REST corepressor 3
chr16_-_74734687 1.300 NM_001142497
NM_152649
MLKL

mixed lineage kinase domain-like

chr17_-_16875388 1.288 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr18_-_31802433 1.266 NM_001198547
NOL4
nucleolar protein 4
chr1_+_203595929 1.265 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr9_+_139557378 1.256 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr16_-_2059759 1.253 NM_178167
ZNF598
zinc finger protein 598
chr12_-_47473424 1.235 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr16_+_88705000 1.230 NM_013278
IL17C
interleukin 17C
chr8_-_23261626 1.229 LOXL2
lysyl oxidase-like 2
chr1_+_150480584 1.219 ECM1
extracellular matrix protein 1
chr6_+_106534210 1.211 PRDM1
PR domain containing 1, with ZNF domain
chr11_-_64570621 1.202 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr2_-_127963342 1.201 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr7_+_143078457 1.185 ZYX
zyxin
chr7_-_105925329 1.182 NAMPT
nicotinamide phosphoribosyltransferase
chr10_-_29923900 1.173 NM_021738
SVIL
supervillin
chr17_+_12569305 1.159 MYOCD
myocardin
chr21_+_34775189 1.158 NM_005534
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr7_+_143078608 1.155 ZYX
zyxin
chr3_+_121796695 1.148 NM_006889
NM_176892
CD86

CD86 molecule

chr1_-_36235422 1.147 NM_001190481
NM_022111
CLSPN

claspin

chr14_-_35183722 1.144 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr6_+_37137882 1.129 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr1_-_153521717 1.126 NM_002960
S100A3
S100 calcium binding protein A3
chr8_-_9008138 1.121 NM_024607
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr7_+_143078399 1.119 ZYX
zyxin
chr4_+_8200918 1.119 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr3_+_171757432 1.118 FNDC3B
fibronectin type III domain containing 3B
chr16_+_68877492 1.117 NM_024562
TMCO7
transmembrane and coiled-coil domains 7
chr21_+_34775729 1.111 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_40610875 1.108 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr11_-_18270167 1.102 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr1_-_24469571 1.099 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr19_+_16187315 1.096 TPM4
tropomyosin 4
chr20_+_44509847 1.093 NM_080603
ZSWIM1
zinc finger, SWIM-type containing 1
chr1_-_17307107 1.093 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr19_-_45826131 1.092 CKM
creatine kinase, muscle
chr1_-_93426998 1.089 NM_001006605
NM_001252269
NM_001252270
NM_001252273
FAM69A



family with sequence similarity 69, member A



chr9_+_127539382 1.082 NM_182487
OLFML2A
olfactomedin-like 2A
chr12_-_99038705 1.081 IKBIP
IKBKB interacting protein
chr19_-_1512997 1.077 ADAMTSL5
ADAMTS-like 5
chr7_+_143078444 1.076 ZYX
zyxin
chr3_-_50336662 1.071 NM_001200016
NM_012191
NM_001200030
NM_001200031
NM_001200032
NM_003549
NAT6

HYAL3



N-acetyltransferase 6 (GCN5-related)

hyaluronoglucosaminidase 3



chr11_+_70244588 1.071 NM_001184740
NM_005231
NM_138565
CTTN


cortactin


chr1_+_154377668 1.065 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr7_+_143078395 1.063 ZYX
zyxin
chr7_+_143078447 1.063 ZYX
zyxin
chr14_+_65171243 1.047 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr7_+_143078358 1.040 NM_001010972
NM_003461
ZYX

zyxin

chr21_+_34775740 1.036 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_38810751 1.020 KCNK6
potassium channel, subfamily K, member 6
chr11_+_118478305 1.019 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr8_+_90770201 1.014 RIPK2
receptor-interacting serine-threonine kinase 2
chr16_+_30064470 1.010 ALDOA
aldolase A, fructose-bisphosphate
chr19_+_38810461 1.008 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr7_-_102920840 0.999 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr17_+_40610915 0.997 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr10_-_90611675 0.992 NM_144590
ANKRD22
ankyrin repeat domain 22
chr5_-_171615320 0.992 NM_005990
STK10
serine/threonine kinase 10
chr10_+_102759607 0.992 LZTS2
leucine zipper, putative tumor suppressor 2
chr1_-_209825673 0.992 NM_001127641
LAMB3
laminin, beta 3
chr10_-_135090325 0.990 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr19_+_41223282 0.989 ITPKC
inositol-trisphosphate 3-kinase C
chr4_-_74964836 0.989 CXCL2
chemokine (C-X-C motif) ligand 2
chr19_+_41222915 0.979 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chr12_-_28124915 0.978 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr8_-_23261675 0.978 NM_002318
LOXL2
lysyl oxidase-like 2
chr8_+_86376130 0.978 NM_000067
CA2
carbonic anhydrase II
chr9_-_132515290 0.976 NM_004878
PTGES
prostaglandin E synthase
chr17_+_38474472 0.975 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr6_-_131384321 0.971 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_-_14640048 0.969 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr3_+_171757413 0.968 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr1_-_204120909 0.968 ETNK2
ethanolamine kinase 2
chr10_-_75634219 0.968 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma






Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.20 1.17e-08 GO:0050794 regulation of cellular process
1.19 1.43e-08 GO:0050789 regulation of biological process
1.42 3.40e-08 GO:0048519 negative regulation of biological process
1.11 1.09e-07 GO:0009987 cellular process
1.17 1.14e-07 GO:0065007 biological regulation
1.43 1.33e-07 GO:0048523 negative regulation of cellular process
1.30 4.85e-07 GO:0023052 signaling
1.39 5.02e-07 GO:0048522 positive regulation of cellular process
1.36 5.30e-07 GO:0048518 positive regulation of biological process
1.31 1.55e-06 GO:0007165 signal transduction
1.57 1.46e-05 GO:0010646 regulation of cell communication
1.40 2.41e-05 GO:0048583 regulation of response to stimulus
1.44 2.55e-05 GO:0023051 regulation of signaling
1.50 3.90e-05 GO:0002376 immune system process
1.47 3.97e-05 GO:0009966 regulation of signal transduction
1.24 8.03e-05 GO:0051716 cellular response to stimulus
1.56 8.92e-05 GO:0042127 regulation of cell proliferation
1.67 1.06e-04 GO:0002682 regulation of immune system process
1.52 2.40e-04 GO:0042981 regulation of apoptosis
1.52 2.46e-04 GO:0043067 regulation of programmed cell death
1.62 3.27e-04 GO:0006955 immune response
1.51 4.04e-04 GO:0010941 regulation of cell death
1.78 1.33e-03 GO:0002684 positive regulation of immune system process
1.50 1.61e-03 GO:0009605 response to external stimulus
1.48 2.06e-03 GO:0032268 regulation of cellular protein metabolic process
1.46 2.57e-03 GO:0051246 regulation of protein metabolic process
1.69 3.24e-03 GO:0006935 chemotaxis
1.69 3.24e-03 GO:0042330 taxis
1.24 3.44e-03 GO:0060255 regulation of macromolecule metabolic process
1.88 3.99e-03 GO:0031347 regulation of defense response
2.02 4.02e-03 GO:0002694 regulation of leukocyte activation
1.99 5.56e-03 GO:0050865 regulation of cell activation
2.05 7.79e-03 GO:0051249 regulation of lymphocyte activation
1.25 8.54e-03 GO:0048731 system development
2.14 8.77e-03 GO:0002696 positive regulation of leukocyte activation
1.15 9.83e-03 GO:0050896 response to stimulus
1.24 9.98e-03 GO:0048856 anatomical structure development
1.42 1.03e-02 GO:0010604 positive regulation of macromolecule metabolic process
2.10 1.37e-02 GO:0050867 positive regulation of cell activation
1.17 1.68e-02 GO:0043170 macromolecule metabolic process
1.50 1.89e-02 GO:0048584 positive regulation of response to stimulus
3.42 1.93e-02 GO:0045621 positive regulation of lymphocyte differentiation
1.55 2.19e-02 GO:0042325 regulation of phosphorylation
1.66 2.23e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.23 2.26e-02 GO:0019538 protein metabolic process
2.12 2.45e-02 GO:0051251 positive regulation of lymphocyte activation
1.20 2.52e-02 GO:0032502 developmental process
1.21 2.61e-02 GO:0007275 multicellular organismal development
1.19 2.71e-02 GO:0019222 regulation of metabolic process
1.70 2.80e-02 GO:0007243 intracellular protein kinase cascade
1.70 2.80e-02 GO:0023014 signal transduction via phosphorylation event
1.46 3.00e-02 GO:0009611 response to wounding
1.38 3.16e-02 GO:0009893 positive regulation of metabolic process
1.62 3.21e-02 GO:0008284 positive regulation of cell proliferation
1.43 3.62e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.93 3.65e-02 GO:0045619 regulation of lymphocyte differentiation
2.19 3.89e-02 GO:0034762 regulation of transmembrane transport
1.55 3.99e-02 GO:0001932 regulation of protein phosphorylation
1.14 4.31e-02 GO:0044238 primary metabolic process
1.27 4.49e-02 GO:0042221 response to chemical stimulus
1.53 4.88e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.37 3.47e-06 GO:0005829 cytosol
1.13 5.61e-05 GO:0005737 cytoplasm
1.97 9.51e-05 GO:0015629 actin cytoskeleton
1.31 2.34e-04 GO:0044459 plasma membrane part
1.18 8.24e-03 GO:0071944 cell periphery
2.35 1.22e-02 GO:0005924 cell-substrate adherens junction
1.17 1.26e-02 GO:0005886 plasma membrane
2.08 1.63e-02 GO:0005912 adherens junction
2.27 2.45e-02 GO:0030055 cell-substrate junction
1.13 3.36e-02 GO:0044444 cytoplasmic part
2.28 4.18e-02 GO:0005925 focal adhesion

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 6.82e-13 GO:0005515 protein binding
2.14 1.53e-03 GO:0005126 cytokine receptor binding
1.07 3.24e-03 GO:0005488 binding
3.29 2.98e-02 GO:0003823 antigen binding