Motif ID: NHLH1,2.p2

Z-value: 0.820


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NHLH2chr1_-_1163833230.356.2e-02Click!
NHLH1chr1_+_1603368560.105.9e-01Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_122746544 2.119 SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr2_-_7005764 1.845 NM_207315
 CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_-_26625164 1.765 NM_001007538
 SHISA2
shisa homolog 2 (Xenopus laevis)
chr4_+_75858205 1.560 NM_015393
 PARM1
prostate androgen-regulated mucin-like protein 1
chr17_-_39280377 1.467 NM_031854
 KRTAP4-12
keratin associated protein 4-12
chr16_+_67465019 1.435 NM_000196
 HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr11_+_113930430 1.050 NM_006006
 ZBTB16
zinc finger and BTB domain containing 16
chr8_-_17271015 0.919 NM_004686
 MTMR7
myotubularin related protein 7
chr6_-_90121966 0.862 NM_021244
 RRAGD
Ras-related GTP binding D
chr19_+_18111923 0.858 NM_001025604
 ARRDC2
arrestin domain containing 2
chr17_-_39316982 0.835 NM_032524
 KRTAP4-4
keratin associated protein 4-4
chr6_-_90121656 0.832 RRAGD
Ras-related GTP binding D
chr10_+_94833646 0.802 NM_000783
 CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr12_-_63328857 0.795 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_+_102091399 0.793 NM_020244
 CHPT1
choline phosphotransferase 1
chr17_+_39261640 0.776 NM_001146041
 KRTAP4-9
keratin associated protein 4-9
chr12_-_63328663 0.767 NM_020700
 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr21_+_42688660 0.749 NM_058186
NM_206964
 FAM3B

family with sequence similarity 3, member B

chr6_-_46138584 0.736 NM_021572
 ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr10_-_13043570 0.734 NM_031455
 CCDC3
coiled-coil domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.14 1.20e-02 GO:0050770 regulation of axonogenesis
1.28 1.94e-04 GO:0007399 nervous system development
1.09 4.08e-02 GO:0044237 cellular metabolic process
1.07 1.17e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.97 1.65e-04 GO:0005765 lysosomal membrane
1.81 4.19e-04 GO:0005774 vacuolar membrane
1.78 4.71e-04 GO:0044437 vacuolar part
1.72 2.28e-06 GO:0000323 lytic vacuole
1.72 2.28e-06 GO:0005764 lysosome
1.62 1.73e-05 GO:0005773 vacuole
1.26 1.44e-02 GO:0005794 Golgi apparatus
1.16 3.07e-02 GO:0031090 organelle membrane
1.10 6.48e-04 GO:0044444 cytoplasmic part
1.09 5.23e-07 GO:0043227 membrane-bounded organelle
1.09 6.55e-07 GO:0043231 intracellular membrane-bounded organelle
1.09 1.63e-06 GO:0005737 cytoplasm
1.08 1.47e-10 GO:0044424 intracellular part
1.08 3.29e-10 GO:0005622 intracellular
1.08 4.21e-07 GO:0043226 organelle
1.08 7.42e-07 GO:0043229 intracellular organelle
1.03 6.92e-05 GO:0044464 cell part
1.03 7.37e-05 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.44 2.10e-03 GO:0019904 protein domain specific binding
1.09 4.25e-04 GO:0005515 protein binding