Motif ID: NKX2-2,8.p2

Z-value: 0.707


Transcription factors associated with NKX2-2,8.p2:

Gene SymbolEntrez IDGene Name
NKX2-2 4821 NK2 homeobox 2
NKX2-8 26257 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-8chr14_-_37051785-0.356.0e-02Click!
NKX2-2chr20_-_21494663-0.038.6e-01Click!


Activity profile for motif NKX2-2,8.p2.

activity profile for motif NKX2-2,8.p2


Sorted Z-values histogram for motif NKX2-2,8.p2

Sorted Z-values for motif NKX2-2,8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2,8.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_63638343 4.005 NM_001080537
SNTN
sentan, cilia apical structure protein
chr1_+_104159953 2.674 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr9_-_3223007 2.506


chr3_-_121379757 1.877 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379701 1.871 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr12_-_71551564 1.765 TSPAN8
tetraspanin 8
chr5_+_156820161 1.465 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr20_+_31870940 1.437 NM_033197
BPIFB1
BPI fold containing family B, member 1
chr1_+_244214552 1.376 NM_205768
ZNF238
zinc finger protein 238
chr8_-_110620220 1.341 SYBU
syntabulin (syntaxin-interacting)
chr1_+_244214576 1.327 ZNF238
zinc finger protein 238
chr1_-_161337663 1.319 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr9_-_117150217 1.286 AKNA
AT-hook transcription factor
chr19_+_41430123 1.159 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr3_-_170744458 1.118 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr8_-_133772808 1.104 NM_001145153
NM_144649
TMEM71

transmembrane protein 71

chr13_-_61989654 1.101 NM_022843
PCDH20
protocadherin 20
chr7_+_114055048 1.074 NM_001172766
NM_014491
NM_148898
NM_148900
FOXP2



forkhead box P2



chr11_+_73359734 1.025 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr3_-_167371288 0.964 NM_178824
WDR49
WD repeat domain 49
chr12_+_41831484 0.957 NM_013377
PDZRN4
PDZ domain containing ring finger 4
chr9_-_14086901 0.945 NFIB
nuclear factor I/B
chr3_-_170744767 0.944 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr4_-_110723334 0.934 NM_000204
CFI
complement factor I
chr17_-_38073792 0.928 NM_018530
GSDMB
gasdermin B
chr1_+_104292439 0.916 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr1_+_104198301 0.907 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr2_+_39103102 0.887 NM_001145450
MORN2
MORN repeat containing 2
chr1_+_12806162 0.885 NM_152290
C1orf158
chromosome 1 open reading frame 158
chr16_-_21289637 0.862 CRYM
crystallin, mu
chr20_-_34117447 0.856 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr1_-_26633110 0.812 NM_001077262
NM_183008
UBXN11

UBX domain protein 11

chr5_+_140602914 0.778 NM_018934
PCDHB14
protocadherin beta 14
chr12_-_49582800 0.756 NM_006009
TUBA1A
tubulin, alpha 1a
chr1_+_54359859 0.754 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr4_+_36283243 0.715 NM_001136536
DTHD1
death domain containing 1
chr11_+_36397534 0.702 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr13_-_86373328 0.697 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr7_+_23719743 0.690 NM_001127364
NM_001127365
NM_199136
C7orf46


chromosome 7 open reading frame 46


chr4_-_100356449 0.677 NM_000673
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_151058439 0.675 NM_176876
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr17_+_7591666 0.671 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr5_-_41261539 0.663 NM_001115131
C6
complement component 6
chr11_+_65271145 0.650


chr10_+_115511212 0.648 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr2_+_162272892 0.646 TBR1
T-box, brain, 1
chr16_-_21289571 0.642 CRYM
crystallin, mu
chr13_-_36429798 0.642 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr3_-_15839674 0.640 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr8_+_76452202 0.634 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr6_-_55740358 0.622 NM_021073
BMP5
bone morphogenetic protein 5
chr18_+_55888750 0.612 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_-_55740387 0.609 BMP5
bone morphogenetic protein 5
chr1_-_244006885 0.605 NM_001206729
AKT3
v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr1_+_61869699 0.590 NFIA
nuclear factor I/A
chr4_-_170533536 0.589 NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr1_-_207095198 0.587 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chrX_+_144908927 0.583 NM_004709
CXorf1
chromosome X open reading frame 1
chr9_-_20622476 0.567 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_46782104 0.567 NM_182493
MYLK3
myosin light chain kinase 3
chr4_-_110723127 0.563 CFI
complement factor I
chr15_+_72406598 0.560 NM_001166340
SENP8
SUMO/sentrin specific peptidase family member 8
chr5_+_140220811 0.559 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr6_-_119252887 0.557 NM_017696
MCM9
minichromosome maintenance complex component 9
chr8_-_145770680 0.553 ARHGAP39
Rho GTPase activating protein 39
chr6_-_46922533 0.550 NM_015234
GPR116
G protein-coupled receptor 116
chr5_-_121814781 0.550


chr7_-_120498128 0.535 NM_012338
TSPAN12
tetraspanin 12
chr4_+_128802064 0.534 NM_001190801
PLK4
polo-like kinase 4
chr16_-_23724820 0.531 NM_033266
ERN2
endoplasmic reticulum to nucleus signaling 2
chr2_-_217540722 0.525 IGFBP5
insulin-like growth factor binding protein 5
chr1_+_15272414 0.513 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr18_+_61370193 0.489 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr13_+_24144402 0.488 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr8_+_17829848 0.477 PCM1
pericentriolar material 1
chr9_+_66553254 0.475 MGC21881
uncharacterized locus MGC21881
chr3_-_112359277 0.470 CCDC80
coiled-coil domain containing 80
chr3_-_100712248 0.470 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr13_-_49975734 0.462 NM_030925
CAB39L
calcium binding protein 39-like
chrX_+_47092264 0.452 NM_004651
USP11
ubiquitin specific peptidase 11
chr5_+_159656436 0.445 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr4_-_100356290 0.445 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr3_-_114790221 0.444 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr12_+_121132677 0.430


chr3_+_108015392 0.428 HHLA2
HERV-H LTR-associating 2
chr9_+_127119114 0.426


chrX_+_108779009 0.423 NM_018698
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_217113007 0.421 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr12_+_20963637 0.420 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_41627045 0.415 NM_001031694
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr12_-_90049818 0.405 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chrX_-_84634742 0.398 NM_024921
POF1B
premature ovarian failure, 1B
chr14_+_89060729 0.396 NM_207662
ZC3H14
zinc finger CCCH-type containing 14
chr19_+_41497182 0.395 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr9_-_125941304 0.391 STRBP
spermatid perinuclear RNA binding protein
chr13_-_41556188 0.389 ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_94292816 0.382 PEG10
paternally expressed 10
chr8_+_17822093 0.381 PCM1
pericentriolar material 1
chr1_-_23886284 0.380 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_-_62475060 0.375 NM_001122955
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_+_26624776 0.369 NM_145038
CCDC164
coiled-coil domain containing 164
chr3_+_171561138 0.368 NM_001164436
TMEM212
transmembrane protein 212
chr13_-_107220444 0.362 NM_018011
ARGLU1
arginine and glutamate rich 1
chr4_+_41614911 0.361 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_+_41700736 0.359 LIMCH1
LIM and calponin homology domains 1
chr2_-_163008913 0.356 NM_002054
GCG
glucagon
chr12_+_86268072 0.353 NM_006183
NTS
neurotensin
chr6_-_80247103 0.351 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr22_+_24105207 0.349 NM_182520
C22orf15
chromosome 22 open reading frame 15
chrY_+_16634487 0.345 NM_001206850
NLGN4Y
neuroligin 4, Y-linked
chr7_+_94292737 0.342 PEG10
paternally expressed 10
chr4_-_140060601 0.339 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr20_+_9288446 0.339 NM_000933
PLCB4
phospholipase C, beta 4
chr4_+_186350543 0.337 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr11_+_94277005 0.336 NM_002033
PIWIL4
FUT4
piwi-like 4 (Drosophila)
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr17_-_39165343 0.334 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr7_+_150065330 0.333 REPIN1
replication initiator 1
chr10_-_94003002 0.330 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_58240493 0.328 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_167298382 0.322 POU2F1
POU class 2 homeobox 1
chr16_-_21314371 0.319 NM_001014444
NM_001888
CRYM

crystallin, mu

chr16_+_23194037 0.318 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr1_-_41625539 0.318 NM_001172222
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr6_-_39072412 0.316 C6orf64
chromosome 6 open reading frame 64
chr3_-_155394104 0.315 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr11_-_34533117 0.314 NM_001243081
NM_198381
ELF5

E74-like factor 5 (ets domain transcription factor)

chr12_+_25205488 0.311 LRMP
lymphoid-restricted membrane protein
chr6_+_158734902 0.309


chr16_+_78062985 0.308 NM_001244755
CLEC3A
C-type lectin domain family 3, member A
chr6_-_139613114 0.307 NM_153235
TXLNB
taxilin beta
chr6_+_16143281 0.303 MYLIP
myosin regulatory light chain interacting protein
chr10_+_94594469 0.297 NM_001013848
EXOC6
exocyst complex component 6
chr19_+_49838673 0.296 NM_001040031
NM_001774
CD37

CD37 molecule

chr1_-_226926875 0.292 NM_002221
ITPKB
inositol-trisphosphate 3-kinase B
chr12_+_69742140 0.288 LYZ
lysozyme
chr17_+_26800657 0.284 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr6_-_31648140 0.284 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr2_+_170366211 0.281 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr11_+_125753508 0.281 NM_145014
HYLS1
hydrolethalus syndrome 1
chrX_-_84634396 0.280 POF1B
premature ovarian failure, 1B
chr3_+_88188261 0.279 NM_018293
ZNF654
zinc finger protein 654
chr18_-_61329113 0.278 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr10_-_27529263 0.273 NM_145698
ACBD5
acyl-CoA binding domain containing 5
chr1_+_215178884 0.271 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr15_-_55652777 0.269 CCPG1
cell cycle progression 1
chr9_-_20622433 0.268 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_-_15510209 0.268 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr6_-_33285493 0.268 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr3_+_108541544 0.265 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr4_-_84035908 0.263 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chrX_+_91090459 0.261 NM_001168360
NM_001168361
NM_001168362
NM_001168363
PCDH11X



protocadherin 11 X-linked



chr21_+_42733916 0.259 NM_002463
LOC100131190
MX2
uncharacterized LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr1_+_180601164 0.257 XPR1
xenotropic and polytropic retrovirus receptor 1
chr3_-_69101236 0.257 NM_007114
TMF1
TATA element modulatory factor 1
chr1_-_246670518 0.257 SMYD3
SET and MYND domain containing 3
chr5_+_140792507 0.255 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr13_-_20357125 0.255 NM_001042414
PSPC1
paraspeckle component 1
chr18_+_29671817 0.254 NM_016271
RNF138
ring finger protein 138
chr1_-_146697155 0.253 NM_001144829
NM_001144830
NM_001461
FMO5


flavin containing monooxygenase 5


chr5_+_140261792 0.251 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr5_+_139505519 0.247 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr11_+_65266642 0.246


chr12_-_105322056 0.246 NM_032148
SLC41A2
solute carrier family 41, member 2
chr8_+_17396285 0.245 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr12_+_109826523 0.245 NM_001101421
MYO1H
myosin IH
chr21_+_30400229 0.244 USP16
ubiquitin specific peptidase 16
chr1_+_100326765 0.242 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr12_+_25205180 0.241 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chrX_-_10645726 0.241 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr6_+_144612872 0.241 NM_007124
UTRN
utrophin
chr18_+_61575203 0.238 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr20_-_36152952 0.234 NM_001167823
BLCAP
bladder cancer associated protein
chr19_+_49838646 0.234 CD37
CD37 molecule
chr3_-_71592707 0.233 NM_001244816
FOXP1
forkhead box P1
chrX_+_22050920 0.231 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr1_-_216978708 0.230 NM_001243514
ESRRG
estrogen-related receptor gamma
chrX_-_70473979 0.230 NM_201599
ZMYM3
zinc finger, MYM-type 3
chr1_-_108231122 0.229 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr10_-_116444374 0.229 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr15_+_29033259 0.229 LOC100289656
Dexi homolog (mouse) pseudogene
chr3_+_185046682 0.228 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr19_+_13134782 0.227 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr13_-_70682458 0.227 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr10_+_101542460 0.225 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_-_84035888 0.224 PLAC8
placenta-specific 8
chr8_-_17555158 0.223 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr1_-_109204035 0.222 NM_144584
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr1_+_114493766 0.222 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr5_-_58571916 0.218 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr4_+_41614933 0.218 LIMCH1
LIM and calponin homology domains 1
chr8_-_72268720 0.216 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr6_+_131958441 0.216 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr12_+_53817638 0.214 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr11_+_34654010 0.214 NM_001206616
EHF
ets homologous factor
chr19_+_49838700 0.213 CD37
CD37 molecule
chr9_+_131217433 0.212 NM_153436
ODF2
outer dense fiber of sperm tails 2
chr11_-_128712340 0.211 NM_000220
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr20_+_17674319 0.209 NM_001159495
BANF2
barrier to autointegration factor 2
chr9_+_273025 0.208 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr5_-_41213513 0.207 NM_000065
C6
complement component 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.