Motif ID: NKX3-1.p2

Z-value: 0.894


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23540401-0.144.5e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_192127591 4.874 NM_130782
 RGS18
regulator of G-protein signaling 18
chr5_+_147691988 3.449 NM_032566
 SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr17_-_38859976 2.754 NM_019016
 KRT24
keratin 24
chr3_-_149086884 2.130 TM4SF1
transmembrane 4 L six family member 1
chr20_+_30697291 1.903 NM_014742
 TM9SF4
transmembrane 9 superfamily protein member 4
chr10_+_118187381 1.798 NM_001011709
 PNLIPRP3
pancreatic lipase-related protein 3
chr6_+_134758840 1.792 LOC154092
uncharacterized LOC154092
chr12_+_85430098 1.712 NM_001079910
 LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr1_-_153363544 1.712 NM_002964
 S100A8
S100 calcium binding protein A8
chr2_+_228356287 1.712 AGFG1
ArfGAP with FG repeats 1
chr1_+_84630575 1.711 NM_001242860
NM_001242861
 PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr5_+_92918924 1.675 NM_005654
 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr16_+_55600583 1.664 NM_032330
 CAPNS2
calpain, small subunit 2
chr7_-_41742666 1.599 NM_002192
 INHBA
inhibin, beta A
chrX_-_107682600 1.440 NM_001847
 COL4A6
collagen, type IV, alpha 6
chr7_+_80275967 1.411 CD36
CD36 molecule (thrombospondin receptor)
chr3_-_169487602 1.408 NM_032487
 ARPM1
actin related protein M1
chr1_+_152974222 1.391 NM_001097589
NM_005416
 SPRR3

small proline-rich protein 3

chr4_-_69111333 1.340 NM_182502
 TMPRSS11B
transmembrane protease, serine 11B
chr4_-_103245468 1.316 NM_001135148
 SLC39A8
solute carrier family 39 (zinc transporter), member 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.82 4.94e-02 GO:0019935 cyclic-nucleotide-mediated signaling
1.91 2.73e-04 GO:0006952 defense response
1.23 1.85e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
6.82 4.11e-02 GO:0000159 protein phosphatase type 2A complex
1.92 2.37e-05 GO:0005615 extracellular space
1.78 3.92e-05 GO:0044421 extracellular region part
1.61 2.77e-07 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
12.78 6.38e-03 GO:0005132 interferon-alpha/beta receptor binding
7.95 5.96e-03 GO:0008601 protein phosphatase type 2A regulator activity
7.67 3.27e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity