Motif ID: NKX3-2.p2

Z-value: 1.231


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
NKX3-2 579 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-2chr4_-_13546037-0.319.3e-02Click!


Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_32497925 7.828 NM_002125
 HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr16_+_57406398 6.493 NM_002996
 CX3CL1
chemokine (C-X3-C motif) ligand 1
chr5_-_149792370 6.163 NM_001025158
NM_001025159
NM_004355
 CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr20_+_31870940 5.325 NM_033197
 BPIFB1
BPI fold containing family B, member 1
chr4_-_16077740 5.024 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
 PROM1




prominin 1




chr9_-_34397786 5.021 NM_032596
 C9orf24
chromosome 9 open reading frame 24
chr17_-_74137370 4.964 NM_001454
 FOXJ1
forkhead box J1
chr1_-_161337663 4.847 NM_001013625
 C1orf192
chromosome 1 open reading frame 192
chr6_+_32407618 4.756 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr6_-_32557431 3.994 NM_001243965
NM_002124
 HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr4_-_110723127 3.838 CFI
complement factor I
chr5_-_149792276 3.835 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_-_110723334 3.694 NM_000204
 CFI
complement factor I
chr9_+_34458810 3.604 NM_012144
 DNAI1
dynein, axonemal, intermediate chain 1
chr4_-_149363498 3.602 NM_000901
NM_001166104
 NR3C2

nuclear receptor subfamily 3, group C, member 2

chr12_-_25348031 3.503 NM_001082972
NM_001082973
NM_001204101
NM_001204102
NM_018272
 CASC1




cancer susceptibility candidate 1




chr5_-_35938736 3.393 NM_001042625
NM_144647
 CAPSL

calcyphosine-like

chr11_+_65479685 3.313 KAT5
K(lysine) acetyltransferase 5
chr16_-_21289637 3.114 CRYM
crystallin, mu
chr16_+_82068830 3.040 NM_002153
 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.61 1.62e-04 GO:0016071 mRNA metabolic process
1.61 1.00e-02 GO:0006397 mRNA processing
1.60 2.89e-02 GO:0016568 chromatin modification
1.42 2.77e-03 GO:0016265 death
1.42 3.14e-03 GO:0008219 cell death
1.41 3.25e-02 GO:0012501 programmed cell death
1.39 1.26e-02 GO:0006351 transcription, DNA-dependent
1.37 2.03e-06 GO:0016070 RNA metabolic process
1.31 1.08e-04 GO:0010467 gene expression
1.26 1.13e-03 GO:0090304 nucleic acid metabolic process
1.20 1.65e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 2.46e-03 GO:0044260 cellular macromolecule metabolic process
1.14 1.54e-02 GO:0043170 macromolecule metabolic process
1.06 2.98e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.47 2.31e-04 GO:0044451 nucleoplasm part
1.18 5.28e-08 GO:0005634 nucleus
1.13 3.85e-10 GO:0043231 intracellular membrane-bounded organelle
1.13 5.89e-10 GO:0043227 membrane-bounded organelle
1.12 2.47e-09 GO:0043226 organelle
1.12 2.95e-09 GO:0043229 intracellular organelle
1.09 1.23e-08 GO:0044424 intracellular part
1.08 7.05e-08 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.24 1.82e-03 GO:0008270 zinc ion binding
1.23 9.20e-04 GO:0003677 DNA binding
1.22 1.43e-05 GO:0003676 nucleic acid binding
1.20 2.43e-02 GO:0046914 transition metal ion binding
1.10 2.81e-03 GO:0005515 protein binding
1.06 3.29e-04 GO:0005488 binding