Motif ID: NKX6-1,2.p2

Z-value: 0.999


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-1chr4_-_85419386-0.393.5e-02Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_361365 4.046 NM_001253388
 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr4_-_100273831 3.877 NM_000669
 ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr1_+_104159953 3.062 NM_000699
 AMY2A
amylase, alpha 2A (pancreatic)
chr7_+_23286384 3.050 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_150738232 2.808 CTSS
cathepsin S
chr7_+_23286386 2.769 GPNMB
glycoprotein (transmembrane) nmb
chr4_-_23891608 2.705 NM_013261
 PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr1_-_150738292 2.609 NM_001199739
NM_004079
 CTSS

cathepsin S

chr19_-_9092017 2.526 NM_024690
 MUC16
mucin 16, cell surface associated
chr5_+_94727047 2.409 NM_152548
 FAM81B
family with sequence similarity 81, member B
chr13_+_24144402 2.376 NM_001204459
NM_148957
 TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr18_+_61370193 2.341 NM_080475
 SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr1_-_150738255 2.320 CTSS
cathepsin S
chr21_-_35884503 2.307 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr7_+_23286390 2.298 GPNMB
glycoprotein (transmembrane) nmb
chr18_-_24722757 2.226 NM_001243848
 CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_210501595 2.073 NM_001122834
NM_001170564
 HHAT

hedgehog acyltransferase

chr7_-_137028533 2.043 NM_002825
 PTN
pleiotrophin
chr19_-_3029611 1.944 NM_001144762
 TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr16_+_78062985 1.942 NM_001244755
 CLEC3A
C-type lectin domain family 3, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.44 4.53e-03 GO:0007156 homophilic cell adhesion

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
23.69 3.34e-02 GO:0004556 alpha-amylase activity
23.69 3.34e-02 GO:0016160 amylase activity