Motif ID: NR4A2.p2

Z-value: 0.943


Transcription factors associated with NR4A2.p2:

monomer

Gene SymbolEntrez IDGene Name
NR4A2 4929 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR4A2chr2_-_157189040-0.421.9e-02Click!


Activity profile for motif NR4A2.p2.

activity profile for motif NR4A2.p2


Sorted Z-values histogram for motif NR4A2.p2

Sorted Z-values for motif NR4A2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51568323 2.093 NM_015596
KLK13
kallikrein-related peptidase 13
chr3_-_50340979 1.967 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr19_-_11689765 1.818 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr3_-_123339423 1.674 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr19_-_51472003 1.664 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr2_-_31637598 1.664 NM_000379
XDH
xanthine dehydrogenase
chr2_+_210288668 1.558 NM_001039538
MAP2
microtubule-associated protein 2
chr2_-_31637553 1.525 XDH
xanthine dehydrogenase
chr3_+_121774208 1.510 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr1_+_152881022 1.340 NM_005547
IVL
involucrin
chr15_+_65204053 1.306 NM_182703
ANKDD1A
ankyrin repeat and death domain containing 1A
chr19_-_35992798 1.297 NM_001035516
DMKN
dermokine
chr3_+_100328432 1.296 NM_032787
GPR128
G protein-coupled receptor 128
chr19_-_11689591 1.290 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr22_+_44395090 1.260 NM_001003828
PARVB
parvin, beta
chr14_-_94442894 1.256 ASB2
ankyrin repeat and SOCS box containing 2
chr3_-_123339178 1.223 MYLK
myosin light chain kinase
chr1_-_27732069 1.122 WASF2
WAS protein family, member 2
chr20_+_43344005 1.027 WISP2
WNT1 inducible signaling pathway protein 2
chr22_+_30792929 1.014 NM_001204204
NM_012429
NM_033382
SEC14L2


SEC14-like 2 (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
2.82 1.32e-02 GO:0030048 actin filament-based movement
2.08 1.09e-03 GO:0006936 muscle contraction
1.99 2.76e-03 GO:0003012 muscle system process
1.72 1.09e-02 GO:0030029 actin filament-based process
1.58 3.72e-03 GO:0007010 cytoskeleton organization
1.51 4.03e-02 GO:0019226 transmission of nerve impulse
1.51 4.03e-02 GO:0035637 multicellular organismal signaling
1.50 4.59e-04 GO:0007267 cell-cell signaling
1.47 2.93e-05 GO:0007154 cell communication
1.34 3.79e-02 GO:0022607 cellular component assembly
1.28 3.05e-02 GO:0009653 anatomical structure morphogenesis
1.27 1.11e-03 GO:0065008 regulation of biological quality
1.25 4.83e-02 GO:0007166 cell surface receptor linked signaling pathway
1.20 6.70e-08 GO:0032501 multicellular organismal process
1.20 1.98e-04 GO:0023052 signaling
1.20 3.55e-04 GO:0032502 developmental process
1.20 1.18e-03 GO:0007275 multicellular organismal development
1.20 3.31e-03 GO:0048856 anatomical structure development
1.08 3.04e-05 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.50 6.30e-07 GO:0043292 contractile fiber
2.48 3.19e-06 GO:0030016 myofibril
2.48 4.49e-06 GO:0044449 contractile fiber part
2.38 2.79e-04 GO:0030017 sarcomere
1.80 8.82e-05 GO:0015629 actin cytoskeleton
1.71 3.67e-02 GO:0030141 stored secretory granule
1.42 2.93e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.40 5.18e-03 GO:0031988 membrane-bounded vesicle
1.39 5.59e-03 GO:0031410 cytoplasmic vesicle
1.37 7.80e-03 GO:0005626 insoluble fraction
1.36 2.08e-02 GO:0031982 vesicle
1.33 3.11e-03 GO:0000267 cell fraction
1.30 3.44e-02 GO:0044430 cytoskeletal part
1.28 2.04e-05 GO:0044459 plasma membrane part
1.28 5.08e-05 GO:0005829 cytosol
1.27 6.75e-03 GO:0005856 cytoskeleton
1.21 1.97e-02 GO:0005576 extracellular region
1.16 9.24e-04 GO:0071944 cell periphery
1.16 1.64e-03 GO:0005886 plasma membrane
1.08 4.88e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.99 3.22e-06 GO:0005200 structural constituent of cytoskeleton
1.66 3.83e-03 GO:0003779 actin binding
1.55 1.33e-04 GO:0005198 structural molecule activity
1.53 1.23e-03 GO:0008092 cytoskeletal protein binding
1.51 2.28e-02 GO:0008289 lipid binding
1.40 8.63e-03 GO:0042802 identical protein binding
1.14 5.77e-07 GO:0005515 protein binding