Motif ID: NR5A1,2.p2

Z-value: 2.384


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR5A2chr1_+_199996729-0.631.8e-04Click!
NR5A1chr9_-_127269689-0.232.2e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_67427335 9.545 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr3_+_63638343 7.798 NM_001080537
SNTN
sentan, cilia apical structure protein
chr1_+_104198140 7.760 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_+_162351519 7.498 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr1_-_207119707 7.446 NM_002644
PIGR
polymeric immunoglobulin receptor
chr1_+_104198301 7.384 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr19_+_41594367 7.338 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr6_-_32551993 6.595 HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr11_-_5275904 6.530 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr16_+_67465019 6.399 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr2_+_120189342 6.015 NM_183240
TMEM37
transmembrane protein 37
chr13_+_43355685 5.759 NM_182508
C13orf30
chromosome 13 open reading frame 30
chr1_+_38022514 5.378 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr4_+_41614911 5.278 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr19_-_44831907 5.132 ZFP112
zinc finger protein 112 homolog (mouse)
chr1_-_104239071 5.096 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr11_-_5271035 5.024 NM_000559
HBG1
hemoglobin, gamma A
chr4_-_7044664 4.850 NM_153376
CCDC96
coiled-coil domain containing 96
chr3_-_197676755 4.843 NM_001134435
IQCG
IQ motif containing G
chr19_-_41356193 4.842 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
4.17 1.23e-15 GO:0022904 respiratory electron transport chain
4.17 8.22e-05 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
3.98 1.65e-05 GO:0042773 ATP synthesis coupled electron transport
3.98 1.65e-05 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.75 2.98e-05 GO:0006119 oxidative phosphorylation
3.56 4.26e-14 GO:0045333 cellular respiration
3.26 1.28e-11 GO:0022900 electron transport chain
2.05 4.44e-05 GO:0015980 energy derivation by oxidation of organic compounds
1.72 4.81e-03 GO:0006091 generation of precursor metabolites and energy
1.44 1.34e-02 GO:0055114 oxidation-reduction process
1.21 3.93e-02 GO:0006810 transport
1.09 9.58e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
4.07 8.52e-06 GO:0005747 mitochondrial respiratory chain complex I
4.07 8.52e-06 GO:0030964 NADH dehydrogenase complex
4.07 8.52e-06 GO:0045271 respiratory chain complex I
3.79 6.12e-09 GO:0070469 respiratory chain
3.56 7.91e-07 GO:0005746 mitochondrial respiratory chain
3.13 2.46e-10 GO:0044455 mitochondrial membrane part
2.35 9.31e-12 GO:0005743 mitochondrial inner membrane
2.21 2.26e-10 GO:0019866 organelle inner membrane
2.08 3.91e-11 GO:0031966 mitochondrial membrane
2.05 5.30e-11 GO:0005740 mitochondrial envelope
1.85 5.57e-11 GO:0044429 mitochondrial part
1.70 4.17e-02 GO:0005759 mitochondrial matrix
1.69 1.79e-07 GO:0031967 organelle envelope
1.68 1.64e-07 GO:0031975 envelope
1.55 1.13e-09 GO:0005739 mitochondrion
1.26 3.11e-03 GO:0031090 organelle membrane
1.15 1.95e-04 GO:0044444 cytoplasmic part
1.14 2.11e-03 GO:0044422 organelle part
1.13 1.20e-02 GO:0044446 intracellular organelle part
1.12 6.24e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.91 4.26e-03 GO:0016775 phosphotransferase activity, nitrogenous group as acceptor
4.06 3.63e-05 GO:0003954 NADH dehydrogenase activity
4.06 3.63e-05 GO:0008137 NADH dehydrogenase (ubiquinone) activity
4.06 3.63e-05 GO:0050136 NADH dehydrogenase (quinone) activity
3.49 6.13e-04 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
2.58 4.07e-03 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
1.54 4.98e-04 GO:0016491 oxidoreductase activity