Motif ID: PAX4.p2

Z-value: 0.916


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX4chr7_-_1272555740.019.6e-01Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_32407618 4.089 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr6_+_17282931 2.271 NM_153020
RBM24
RNA binding motif protein 24
chr17_+_72270385 1.980 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr3_+_238274 1.915 NM_001253387
NM_006614
CHL1

cell adhesion molecule with homology to L1CAM (close homolog of L1)

chr12_+_56075418 1.761 METTL7B
methyltransferase like 7B
chr9_-_20622476 1.759 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr13_-_39564857 1.641 NM_001144033
NM_145286
STOML3

stomatin (EPB72)-like 3

chr5_+_94727047 1.636 NM_152548
FAM81B
family with sequence similarity 81, member B
chr3_+_238535 1.572 CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr11_-_114466471 1.555 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr16_-_28608367 1.530 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr11_-_124622133 1.518 VSIG2
V-set and immunoglobulin domain containing 2
chr11_-_114466397 1.507 FAM55D
family with sequence similarity 55, member D
chr6_-_32557431 1.486 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr10_+_52751114 1.389 PRKG1
protein kinase, cGMP-dependent, type I
chr4_-_84030995 1.303 NM_001130716
PLAC8
placenta-specific 8
chr19_+_14544216 1.302 PKN1
protein kinase N1
chr15_+_81426605 1.291 NM_173528
C15orf26
chromosome 15 open reading frame 26
chr4_+_39184023 1.255 NM_025132
WDR19
WD repeat domain 19
chr11_-_62474869 1.125 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_-_81331487 1.113 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr19_+_41430123 1.101 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr10_+_114135013 1.079 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_-_116286570 1.064 ABLIM1
actin binding LIM protein 1
chr11_-_62474810 1.063 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr15_-_40401041 1.052 NM_001003940
BMF
Bcl2 modifying factor
chr11_-_62474666 1.035 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_86085777 1.030 NM_001156474
NM_021827
CCDC81

coiled-coil domain containing 81

chr9_-_4300028 1.026 NM_001042413
GLIS3
GLIS family zinc finger 3
chr19_+_14544100 1.018 NM_002741
PKN1
protein kinase N1
chr12_+_56075329 1.000 NM_152637
METTL7B
methyltransferase like 7B
chr6_-_130031278 0.991 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr2_-_170550859 0.950 NM_001085447
C2orf77
chromosome 2 open reading frame 77
chr9_-_20622433 0.944 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_-_130080823 0.925 NM_018718
CEP41
centrosomal protein 41kDa
chr19_-_37064102 0.912 ZNF529
zinc finger protein 529
chr19_+_50015535 0.899 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_4152182 0.880 NM_152629
GLIS3
GLIS family zinc finger 3
chr16_-_28621279 0.873 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr7_+_26191732 0.871 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr16_-_84273303 0.854 NM_172347
KCNG4
potassium voltage-gated channel, subfamily G, member 4
chr3_+_42530790 0.835 NM_001251882
VIPR1
vasoactive intestinal peptide receptor 1
chr18_-_53089722 0.821 NM_001243233
TCF4
transcription factor 4
chrY_+_2709596 0.808 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chr7_+_133812051 0.799 NM_144648
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr13_-_29292961 0.798 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr10_+_91152321 0.797 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr12_+_32112381 0.796 C12orf35
chromosome 12 open reading frame 35
chr10_+_115511212 0.770 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr7_-_16844606 0.764 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chrY_+_2709630 0.749 RPS4Y1
ribosomal protein S4, Y-linked 1
chr4_+_3465032 0.739 NM_001164673
NM_173660
DOK7

docking protein 7

chr6_-_31845446 0.737 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr22_-_42765179 0.736


chr2_-_65090710 0.720


chr7_+_69064316 0.703 AUTS2
autism susceptibility candidate 2
chr19_+_6135650 0.675 NM_030924
ACSBG2
acyl-CoA synthetase bubblegum family member 2
chr7_+_29603388 0.665 NM_175887
PRR15
proline rich 15
chr11_+_65271145 0.659


chr20_+_9288446 0.655 NM_000933
PLCB4
phospholipase C, beta 4
chr11_-_75379651 0.652 MAP6
microtubule-associated protein 6
chr3_+_186739643 0.640 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chrY_-_15592549 0.638 NM_007125
NM_182659
NM_182660
UTY


ubiquitously transcribed tetratricopeptide repeat gene, Y-linked


chr2_+_170550949 0.635 NM_001199290
NM_001008489
NM_001199285
NM_001199286
NM_001199287
NM_001199288
PHOSPHO2-KLHL23
PHOSPHO2




PHOSPHO2-KLHL23 readthrough
phosphatase, orphan 2




chr2_+_122407564 0.634 LOC254128
uncharacterized LOC254128
chr10_+_7745229 0.628 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_+_32112286 0.625 NM_018169
C12orf35
chromosome 12 open reading frame 35
chr17_-_46622274 0.624 NM_002145
HOXB2
homeobox B2
chr19_-_50316360 0.616 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr5_-_133304274 0.612 NM_020199
C5orf15
chromosome 5 open reading frame 15
chr6_-_32805819 0.598 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_-_20445991 0.589 NM_012400
PLA2G2D
phospholipase A2, group IID
chr12_-_11214892 0.589 NM_176887
TAS2R46
taste receptor, type 2, member 46
chr3_+_9975513 0.588 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr11_+_46740769 0.584 F2
coagulation factor II (thrombin)
chr7_+_69064580 0.580 AUTS2
autism susceptibility candidate 2
chr2_+_217498205 0.580 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr9_-_27573444 0.579 NM_018325
C9orf72
chromosome 9 open reading frame 72
chr3_-_112358510 0.574 CCDC80
coiled-coil domain containing 80
chr6_-_31697953 0.567 DDAH2
dimethylarginine dimethylaminohydrolase 2
chrX_-_99986496 0.565 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr11_-_124622034 0.563 VSIG2
V-set and immunoglobulin domain containing 2
chr11_+_46740736 0.551 NM_000506
F2
coagulation factor II (thrombin)
chr10_+_7745325 0.549 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr21_-_43735705 0.545 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr2_-_191184485 0.544 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chrX_-_63450486 0.527 NM_130388
ASB12
ankyrin repeat and SOCS box containing 12
chr2_+_217498082 0.524 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr5_-_13944588 0.521 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr3_+_186383770 0.511 NM_000412
HRG
histidine-rich glycoprotein
chr3_-_112358758 0.507 CCDC80
coiled-coil domain containing 80
chr2_-_191184770 0.505 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr9_+_129677046 0.504 NM_001190729
NM_001190730
NM_014636
RALGPS1


Ral GEF with PH domain and SH3 binding motif 1


chr11_-_62472901 0.502


chr7_+_48075107 0.502 NM_001100159
C7orf57
chromosome 7 open reading frame 57
chr20_+_9198036 0.502 NM_182797
PLCB4
phospholipase C, beta 4
chr6_-_31698033 0.492 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr5_-_121413906 0.485 LOX
lysyl oxidase
chr1_+_41157493 0.479 NFYC
nuclear transcription factor Y, gamma
chr2_-_85839163 0.473 C2orf68
chromosome 2 open reading frame 68
chr7_+_80267922 0.473 CD36
CD36 molecule (thrombospondin receptor)
chr8_+_74903563 0.471 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr1_-_38397417 0.468 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr14_+_62584120 0.464 FLJ43390
uncharacterized LOC646113
chr18_-_53255734 0.455 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr5_+_139505519 0.448 NM_001007189
IGIP
IgA-inducing protein homolog (Bos taurus)
chr7_+_100728719 0.439 NM_030961
TRIM56
tripartite motif containing 56
chr19_+_11708234 0.435 NM_145295
ZNF627
zinc finger protein 627
chr1_-_1677430 0.431 NM_001199787
NM_182838
SLC35E2B
SLC35E2

solute carrier family 35, member E2B
solute carrier family 35, member E2

chrX_+_16964730 0.430 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr8_-_71581354 0.427 LACTB2
lactamase, beta 2
chr1_+_212788359 0.425 NM_001206486
ATF3
activating transcription factor 3
chrX_-_48056198 0.419 NM_021015
NM_175723
SSX5

synovial sarcoma, X breakpoint 5

chr13_-_20110884 0.415 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr8_-_71581419 0.412 NM_016027
LACTB2
lactamase, beta 2
chr5_-_121413967 0.409 LOX
lysyl oxidase
chr3_-_23958500 0.409 NM_020345
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr2_-_217560247 0.407 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_+_172389827 0.407 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr1_-_89591685 0.403 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr3_-_112359251 0.401 CCDC80
coiled-coil domain containing 80
chr5_+_139027868 0.401 CXXC5
CXXC finger protein 5
chr10_-_116286661 0.400 NM_006720
ABLIM1
actin binding LIM protein 1
chr1_+_87794548 0.400 LMO4
LIM domain only 4
chr9_+_92219926 0.399 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr3_-_21792815 0.397 NM_024697
ZNF385D
zinc finger protein 385D
chr8_-_21771111 0.397 NM_003974
DOK2
docking protein 2, 56kDa
chr5_+_36608430 0.395 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr17_+_72322350 0.395 NM_153209
KIF19
kinesin family member 19
chr1_+_210001363 0.386 DIEXF
digestive organ expansion factor homolog (zebrafish)
chrX_+_110187468 0.384 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr18_+_61575203 0.373 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr16_+_15528324 0.371 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr16_+_10479911 0.371 ATF7IP2
activating transcription factor 7 interacting protein 2
chrY_-_21906628 0.367 NM_001146705
NM_001146706
NM_004653
KDM5D


lysine (K)-specific demethylase 5D


chr7_-_124405029 0.363 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr10_+_7745341 0.363 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr12_+_110906203 0.363 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr2_-_85839147 0.361 C2orf68
chromosome 2 open reading frame 68
chr12_-_71551564 0.352 TSPAN8
tetraspanin 8
chr19_-_45996470 0.351 NM_206901
RTN2
reticulon 2
chr7_-_96654128 0.350 NM_005221
DLX5
distal-less homeobox 5
chr18_+_72922725 0.343 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr22_+_29449877 0.343 ZNRF3
zinc and ring finger 3
chr15_+_40697977 0.343 IVD
isovaleryl-CoA dehydrogenase
chr19_-_49622278 0.342 NM_018111
C19orf73
chromosome 19 open reading frame 73
chr17_-_46035109 0.339 NM_024320
PRR15L
proline rich 15-like
chr5_+_161494647 0.338 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr17_-_47841468 0.337 FAM117A
family with sequence similarity 117, member A
chr1_-_150669499 0.334 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr1_+_41157406 0.332 NFYC
nuclear transcription factor Y, gamma
chr4_+_492988 0.331 NM_001127178
NM_017733
PIGG

phosphatidylinositol glycan anchor biosynthesis, class G

chr4_+_140586921 0.331 NM_001204366
NM_001204367
NM_001204368
NM_002413
MGST2



microsomal glutathione S-transferase 2



chr17_+_53344966 0.330 HLF
hepatic leukemia factor
chr11_-_124622085 0.330 NM_014312
VSIG2
V-set and immunoglobulin domain containing 2
chr17_-_71088814 0.330 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr3_-_112359277 0.329 CCDC80
coiled-coil domain containing 80
chr4_-_140060601 0.329 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr19_+_55141907 0.327 NM_001081638
NM_001081639
NM_001081637
LILRB1


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1


chr5_+_139027955 0.327 CXXC5
CXXC finger protein 5
chr1_+_210001399 0.325 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr2_-_222436996 0.324 NM_004438
EPHA4
EPH receptor A4
chr1_+_46016524 0.315 AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr1_+_41157475 0.311 NFYC
nuclear transcription factor Y, gamma
chr6_+_159070994 0.310 NM_001009991
NM_001242384
NM_001242394
NM_001242395
SYTL3



synaptotagmin-like 3



chr20_-_34117447 0.310 NM_001145350
C20orf173
chromosome 20 open reading frame 173
chr8_+_41348126 0.309 NM_001002296
GOLGA7
golgin A7
chr6_+_29894105 0.308


chr8_+_41348105 0.307 GOLGA7
golgin A7
chr4_+_81952118 0.306 NM_001201
BMP3
bone morphogenetic protein 3
chr2_-_119605758 0.300 NM_001426
EN1
engrailed homeobox 1
chr1_+_46016454 0.300 NM_001202413
NM_001202414
NM_006066
NM_153326
AKR1A1



aldo-keto reductase family 1, member A1 (aldehyde reductase)



chr9_+_27109138 0.299 NM_000459
TEK
TEK tyrosine kinase, endothelial
chrX_+_114524291 0.298 NM_016383
LUZP4
leucine zipper protein 4
chr2_+_99757947 0.298 NM_144706
C2orf15
chromosome 2 open reading frame 15
chr4_+_76439653 0.296 NM_144721
THAP6
THAP domain containing 6
chr6_+_55039070 0.296 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr16_+_70148213 0.295 PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr5_+_139876504 0.294 ANKHD1
ankyrin repeat and KH domain containing 1
chr10_-_61900659 0.294 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_54457723 0.291 NM_001126328
LNX1
ligand of numb-protein X 1
chr14_+_55738871 0.291 NM_152231
FBXO34
F-box protein 34
chr1_-_26644755 0.289 NM_145345
UBXN11
UBX domain protein 11
chr1_+_41157428 0.289 NFYC
nuclear transcription factor Y, gamma
chr20_-_20036685 0.285 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)
chr17_-_71088820 0.284 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr12_+_113344811 0.283 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr7_+_150382783 0.282 NM_015660
GIMAP2
GTPase, IMAP family member 2
chr15_+_40698000 0.278 IVD
isovaleryl-CoA dehydrogenase
chr2_+_12856813 0.278 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr11_+_46299161 0.276 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr8_+_41348094 0.275 GOLGA7
golgin A7
chr11_+_34460421 0.274 NM_001752
CAT
catalase
chr11_+_27062508 0.274 NM_003986
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr18_+_29671925 0.272 RNF138
ring finger protein 138
chr1_+_41157349 0.270 NFYC
nuclear transcription factor Y, gamma
chr17_-_47841517 0.270 NM_030802
FAM117A
family with sequence similarity 117, member A
chr3_-_146187087 0.268 NM_001199978
PLSCR2
phospholipid scramblase 2
chr10_+_93558281 0.268 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_-_173962050 0.267 NM_172071
RC3H1
ring finger and CCCH-type domains 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.