Motif ID: PAX5.p2

Z-value: 1.495


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37034358-0.431.8e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_245133652 7.230 EFCAB2
EF-hand calcium binding domain 2
chr1_+_245133628 7.167 NM_001143943
 EFCAB2
EF-hand calcium binding domain 2
chr10_+_82116557 5.994 NM_032372
 DYDC2
DPY30 domain containing 2
chr19_+_708766 5.581 NM_001040134
NM_002579
 PALM

paralemmin

chr1_-_22469414 5.251 NM_030761
 WNT4
wingless-type MMTV integration site family, member 4
chr22_-_50970542 4.761 ODF3B
outer dense fiber of sperm tails 3B
chr7_-_123174572 4.582 NM_178827
 IQUB
IQ motif and ubiquitin domain containing
chr8_+_136469557 4.518 NM_006558
 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr13_+_35516390 4.273 NM_015678
 NBEA
neurobeachin
chr1_+_205538164 4.265 MFSD4
major facilitator superfamily domain containing 4
chr1_+_205538111 4.175 NM_181644
 MFSD4
major facilitator superfamily domain containing 4
chr1_-_23810721 4.024 NM_001143778
NM_017707
 ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr10_+_135192694 3.868 NM_152911
NM_207127
NM_207128
 PAOX


polyamine oxidase (exo-N4-amino)


chr19_-_821913 3.846 NM_024888
 LPPR3
lipid phosphate phosphatase-related protein type 3
chr17_-_63557764 3.788 AXIN2
axin 2
chr21_-_45759077 3.658 C21orf2
chromosome 21 open reading frame 2
chr11_-_46867788 3.606 CKAP5
cytoskeleton associated protein 5
chr14_-_95786095 3.560 NM_024734
 CLMN
calmin (calponin-like, transmembrane)
chr18_-_24765178 3.434 NM_031422
 CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr14_+_105953531 3.413 CRIP1
cysteine-rich protein 1 (intestinal)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 82 entries
enrichment   p-value GO term description
1.53 2.08e-02 GO:0016569 covalent chromatin modification
1.52 3.76e-02 GO:0016570 histone modification
1.45 1.55e-04 GO:0016568 chromatin modification
1.36 1.90e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.34 5.64e-04 GO:0000902 cell morphogenesis
1.33 7.20e-04 GO:0032989 cellular component morphogenesis
1.33 7.18e-03 GO:0032990 cell part morphogenesis
1.33 9.31e-03 GO:0048858 cell projection morphogenesis
1.32 1.58e-03 GO:0010629 negative regulation of gene expression
1.32 6.15e-03 GO:0051253 negative regulation of RNA metabolic process
1.32 7.36e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.31 1.20e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.31 2.68e-03 GO:0030030 cell projection organization
1.30 2.70e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.30 5.66e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.30 5.80e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30 7.24e-03 GO:0009057 macromolecule catabolic process
1.30 4.95e-02 GO:0044265 cellular macromolecule catabolic process
1.29 4.05e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.29 5.28e-03 GO:0009890 negative regulation of biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
1.79 7.14e-04 GO:0016585 chromatin remodeling complex
1.35 1.55e-02 GO:0005815 microtubule organizing center
1.27 3.24e-14 GO:0044428 nuclear part
1.27 1.58e-03 GO:0044451 nucleoplasm part
1.26 7.48e-11 GO:0031981 nuclear lumen
1.26 1.57e-07 GO:0005654 nucleoplasm
1.24 2.38e-02 GO:0015630 microtubule cytoskeleton
1.23 3.54e-02 GO:0031967 organelle envelope
1.22 1.16e-09 GO:0070013 intracellular organelle lumen
1.21 3.62e-09 GO:0031974 membrane-enclosed lumen
1.21 7.22e-09 GO:0043233 organelle lumen
1.21 2.24e-08 GO:0005829 cytosol
1.21 8.85e-03 GO:0005794 Golgi apparatus
1.19 2.02e-25 GO:0005634 nucleus
1.16 9.20e-37 GO:0043227 membrane-bounded organelle
1.16 9.08e-03 GO:0012505 endomembrane system
1.15 3.71e-36 GO:0043231 intracellular membrane-bounded organelle
1.15 1.01e-03 GO:0031090 organelle membrane
1.14 7.28e-35 GO:0043226 organelle
1.14 2.26e-15 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
3.19 1.28e-02 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
1.55 7.19e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.37 4.13e-02 GO:0005083 small GTPase regulator activity
1.36 6.47e-03 GO:0000988 protein binding transcription factor activity
1.36 6.47e-03 GO:0000989 transcription factor binding transcription factor activity
1.35 8.90e-03 GO:0003712 transcription cofactor activity
1.32 4.21e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.32 5.72e-03 GO:0030695 GTPase regulator activity
1.27 5.41e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.27 3.83e-03 GO:0043565 sequence-specific DNA binding
1.26 1.15e-03 GO:0016301 kinase activity
1.25 7.92e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.19 4.48e-02 GO:0030528 transcription regulator activity
1.18 4.55e-04 GO:0016740 transferase activity
1.17 5.90e-03 GO:0030554 adenyl nucleotide binding
1.17 9.73e-03 GO:0005524 ATP binding
1.17 1.09e-02 GO:0032559 adenyl ribonucleotide binding
1.16 8.54e-05 GO:0000166 nucleotide binding
1.14 1.34e-05 GO:0003676 nucleic acid binding
1.14 1.75e-03 GO:0003677 DNA binding