Motif ID: PAX5.p2

Z-value: 1.495


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37034358-0.431.8e-02Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_245133652 7.230 EFCAB2
EF-hand calcium binding domain 2
chr1_+_245133628 7.167 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr10_+_82116557 5.994 NM_032372
DYDC2
DPY30 domain containing 2
chr19_+_708766 5.581 NM_001040134
NM_002579
PALM

paralemmin

chr1_-_22469414 5.251 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr22_-_50970542 4.761 ODF3B
outer dense fiber of sperm tails 3B
chr7_-_123174572 4.582 NM_178827
IQUB
IQ motif and ubiquitin domain containing
chr8_+_136469557 4.518 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr13_+_35516390 4.273 NM_015678
NBEA
neurobeachin
chr1_+_205538164 4.265 MFSD4
major facilitator superfamily domain containing 4
chr1_+_205538111 4.175 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr1_-_23810721 4.024 NM_001143778
NM_017707
ASAP3

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

chr10_+_135192694 3.868 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr19_-_821913 3.846 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr17_-_63557764 3.788 AXIN2
axin 2
chr21_-_45759077 3.658 C21orf2
chromosome 21 open reading frame 2
chr11_-_46867788 3.606 CKAP5
cytoskeleton associated protein 5
chr14_-_95786095 3.560 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr18_-_24765178 3.434 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr14_+_105953531 3.413 CRIP1
cysteine-rich protein 1 (intestinal)
chr7_-_158380360 3.403 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr2_+_8822112 3.376 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr1_-_23810627 3.373 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr14_+_100259445 3.361 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr16_+_67465019 3.335 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr2_+_11295569 3.307 PQLC3
PQ loop repeat containing 3
chr2_+_11295539 3.277 NM_152391
PQLC3
PQ loop repeat containing 3
chr8_-_80679897 3.196 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr19_-_821966 3.117 LPPR3
lipid phosphate phosphatase-related protein type 3
chr21_-_45759234 2.932 C21orf2
chromosome 21 open reading frame 2
chr2_+_121103670 2.886 NM_002193
INHBB
inhibin, beta B
chr19_+_32897021 2.872 NM_207325
DPY19L3
dpy-19-like 3 (C. elegans)
chr6_+_160148485 2.865 WTAP
Wilms tumor 1 associated protein
chr16_-_67427335 2.784 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr17_-_63557615 2.753 NM_004655
AXIN2
axin 2
chr5_+_156693051 2.738 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr22_+_39853534 2.710 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_-_34937831 2.594 NM_015957
APIP
APAF1 interacting protein
chr9_+_36136710 2.574 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr3_+_113666544 2.567 NM_173570
ZDHHC23
zinc finger, DHHC-type containing 23
chr3_+_186648515 2.552 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr22_+_39853316 2.504 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr14_-_92302612 2.494 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr22_-_31741761 2.439 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr15_-_52587851 2.436 NM_018728
MYO5C
myosin VC
chr1_+_197871681 2.415 NM_001024594
C1orf53
chromosome 1 open reading frame 53
chr16_-_88923233 2.414 GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr15_-_68521921 2.372 NM_017882
CLN6
ceroid-lipofuscinosis, neuronal 6, late infantile, variant
chr16_+_89724436 2.341 C16orf55
chromosome 16 open reading frame 55
chr16_-_67700571 2.316 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr16_-_21289637 2.239 CRYM
crystallin, mu
chr15_-_90358057 2.235 NM_001150
ANPEP
alanyl (membrane) aminopeptidase
chr20_-_40246991 2.220 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chr19_-_14316980 2.216 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr7_-_131241321 2.215 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr11_+_113185250 2.201 NM_017868
TTC12
tetratricopeptide repeat domain 12
chr3_+_186648273 2.193 NM_173216
NM_173217
ST6GAL1

ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

chr1_+_11333244 2.188 NM_013319
UBIAD1
UbiA prenyltransferase domain containing 1
chr7_-_117513527 2.163 NM_033427
CTTNBP2
cortactin binding protein 2
chr10_+_22634373 2.159 NM_001253854
NM_001253855
NM_012443
NM_172242
SPAG6



sperm associated antigen 6



chr2_+_10183630 2.151 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr20_-_39317875 2.148 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr15_-_93632161 2.146 NM_020211
RGMA
RGM domain family, member A
chr16_+_80574853 2.140 NM_130897
DYNLRB2
dynein, light chain, roadblock-type 2
chr16_-_66959418 2.134 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr16_-_21289571 2.102 CRYM
crystallin, mu
chr6_-_109804432 2.098 NM_001164313
NM_014797
ZBTB24

zinc finger and BTB domain containing 24

chr9_+_140135738 2.075 TUBB4B
tubulin, beta 4B class IVb
chr16_+_58283819 2.073 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr6_+_19837599 2.026 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr19_-_291168 2.023 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr5_-_114632240 2.009 NM_001040440
CCDC112
coiled-coil domain containing 112
chr13_-_114018365 1.994 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr19_+_8455243 1.966 RAB11B
RAB11B, member RAS oncogene family
chr5_+_10442065 1.966 ROPN1L
rhophilin associated tail protein 1-like
chr9_+_140135742 1.952 TUBB4B
tubulin, beta 4B class IVb
chr10_+_35415768 1.952 NM_001881
NM_182850
NM_182853
NM_183013
CREM



cAMP responsive element modulator



chr10_+_88516340 1.925 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr13_-_114018201 1.922 GRTP1
growth hormone regulated TBC protein 1
chr4_-_1166547 1.915 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr9_+_131218678 1.897 NM_153433
NM_153440
ODF2

outer dense fiber of sperm tails 2

chr11_-_2018703 1.891 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr1_-_223537400 1.873 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr9_+_140135698 1.864 NM_006088
TUBB4B
tubulin, beta 4B class IVb
chr19_+_32896515 1.857 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr19_+_4343523 1.846 NM_001159846
NM_032868
MPND

MPN domain containing

chr1_+_38022514 1.830 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr10_-_82116499 1.828 NM_138812
DYDC1
DPY30 domain containing 1
chr2_+_132285469 1.816 NM_138770
CCDC74A
coiled-coil domain containing 74A
chr11_+_61276271 1.816 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr9_-_86432546 1.812 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr1_-_236445294 1.807 NM_019891
ERO1LB
ERO1-like beta (S. cerevisiae)
chr19_+_8455265 1.802 RAB11B
RAB11B, member RAS oncogene family
chr21_-_45759268 1.798 NM_004928
C21orf2
chromosome 21 open reading frame 2
chr1_-_235812994 1.795 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr11_-_93276513 1.795 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr4_+_1005609 1.795 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr9_+_71320105 1.792 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_-_90121966 1.791 NM_021244
RRAGD
Ras-related GTP binding D
chr10_+_134973935 1.783 NM_152643
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr18_+_67956242 1.773 SOCS6
suppressor of cytokine signaling 6
chr19_-_48825150 1.766 CCDC114
coiled-coil domain containing 114
chr13_+_27131879 1.749 WASF3
WAS protein family, member 3
chr9_+_131219185 1.741 NM_153437
ODF2
outer dense fiber of sperm tails 2
chr19_-_291335 1.734 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr4_-_1166458 1.720 SPON2
spondin 2, extracellular matrix protein
chr9_-_90589360 1.702 CDK20
cyclin-dependent kinase 20
chr4_+_187065994 1.692 NM_015398
FAM149A
family with sequence similarity 149, member A
chr1_+_113933474 1.686 NM_001142782
NM_152900
MAGI3

membrane associated guanylate kinase, WW and PDZ domain containing 3

chr2_-_86564632 1.677 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr6_-_99395807 1.671 NM_012160
FBXL4
F-box and leucine-rich repeat protein 4
chr1_+_111889194 1.668 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr6_+_163148163 1.661 NM_001080378
NM_152410
PACRG

PARK2 co-regulated

chr7_-_117513466 1.644 CTTNBP2
cortactin binding protein 2
chr16_+_89724175 1.644 NM_153025
C16orf55
chromosome 16 open reading frame 55
chr6_-_99395774 1.637 FBXL4
F-box and leucine-rich repeat protein 4
chrX_-_38186782 1.625 NM_000328
NM_001034853
RPGR

retinitis pigmentosa GTPase regulator

chrX_-_152864621 1.611 NM_001130997
NM_152274
FAM58A

family with sequence similarity 58, member A

chr2_-_95825262 1.609 NM_032788
ZNF514
zinc finger protein 514
chr4_-_1166378 1.606 SPON2
spondin 2, extracellular matrix protein
chr16_-_3285359 1.595 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr13_+_21141283 1.585 IFT88
intraflagellar transport 88 homolog (Chlamydomonas)
chr13_+_21141207 1.584 NM_006531
NM_175605
IFT88

intraflagellar transport 88 homolog (Chlamydomonas)

chr4_-_1166364 1.568 SPON2
spondin 2, extracellular matrix protein
chr19_+_8455200 1.565 NM_004218
RAB11B
RAB11B, member RAS oncogene family
chr5_+_56111379 1.565 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr11_-_67572670 1.561 FAM86C2P
family with sequence similarity 86, member A pseudogene
chr3_+_54156573 1.554 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr11_+_827584 1.547 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr10_+_12391728 1.540 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr17_-_19281494 1.528 NM_001243475
B9D1
B9 protein domain 1
chr4_-_37687932 1.527 NM_001085399
NM_001085400
RELL1

RELT-like 1

chr22_-_41593466 1.522


chr3_-_66551341 1.522 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr21_+_33784751 1.519 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr22_-_39548448 1.515 NM_175709
CBX7
chromobox homolog 7
chr17_+_35849997 1.502 DUSP14
dual specificity phosphatase 14
chr7_+_129142319 1.502 NM_001195243
LOC100287482
uncharacterized LOC100287482
chr6_-_39197225 1.485 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr8_+_25042066 1.477 DOCK5
dedicator of cytokinesis 5
chr10_+_12391708 1.463 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr12_+_110562139 1.460 NM_001143779
NM_014055
NM_031473
IFT81


intraflagellar transport 81 homolog (Chlamydomonas)


chr1_+_38259458 1.445 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr16_-_52581713 1.429 NM_001146188
TOX3
TOX high mobility group box family member 3
chr20_+_9049660 1.427 NM_001172646
PLCB4
phospholipase C, beta 4
chrX_-_152864435 1.408 FAM58A
family with sequence similarity 58, member A
chr16_+_23765947 1.407 NM_022097
CHP2
calcineurin B homologous protein 2
chr22_-_39190103 1.407 DNAL4
dynein, axonemal, light chain 4
chr1_+_222791151 1.405 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr12_-_113658826 1.396 NM_138451
IQCD
IQ motif containing D
chr3_+_169755782 1.395 GPR160
G protein-coupled receptor 160
chr1_-_48937791 1.392 NM_019073
SPATA6
spermatogenesis associated 6
chr1_+_11333502 1.389 UBIAD1
UbiA prenyltransferase domain containing 1
chr4_-_154710207 1.371 NM_003013
SFRP2
secreted frizzled-related protein 2
chr1_+_18434236 1.369 NM_032880
IGSF21
immunoglobin superfamily, member 21
chr4_+_72052354 1.368 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr7_+_2598611 1.362 NM_001100390
NM_152558
IQCE

IQ motif containing E

chr3_-_15900928 1.353 NM_015199
ANKRD28
ankyrin repeat domain 28
chr8_-_145115565 1.351 NM_017570
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr4_-_3957141 1.349 FAM86EP
family with sequence similarity 86, member A pseudogene
chr18_-_12377168 1.343 AFG3L2
AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr15_+_82555101 1.341 NM_001008226
FAM154B
family with sequence similarity 154, member B
chr19_+_17581276 1.337 NM_198580
SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr22_-_21213012 1.334 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_33048554 1.331 NM_001242524
NM_001242525
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr13_+_37006628 1.328 CCNA1
cyclin A1
chr22_+_29279573 1.327 NM_001206998
ZNRF3
zinc and ring finger 3
chr14_-_100625931 1.326 NM_206918
DEGS2
delta(4)-desaturase, sphingolipid 2
chr8_+_136470108 1.320 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr3_+_169755733 1.315 NM_014373
GPR160
G protein-coupled receptor 160
chr18_+_29671925 1.305 RNF138
ring finger protein 138
chr12_-_48744553 1.303 NM_001172681
NM_152320
ZNF641

zinc finger protein 641

chr19_-_51504799 1.297 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chrX_+_152240726 1.292 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr19_+_3094266 1.284 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr8_-_12051533 1.282 NM_001083537
FAM86B2
FAM86B1
family with sequence similarity 86, member B2
family with sequence similarity 86, member B1
chr6_-_90121656 1.281 RRAGD
Ras-related GTP binding D
chr3_+_52444514 1.280 NM_016483
NM_173341
PHF7

PHD finger protein 7

chr5_-_54468833 1.269 NM_001145734
NM_001170402
NM_152623
CDC20B


cell division cycle 20 homolog B (S. cerevisiae)


chr6_-_46138584 1.266 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr12_+_50355278 1.262 NM_001651
AQP5
aquaporin 5
chr12_+_104458235 1.261 NM_013320
HCFC2
host cell factor C2
chr2_-_99552677 1.254 NM_207362
C2orf55
chromosome 2 open reading frame 55
chr22_-_21213099 1.252 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr19_+_3094528 1.248 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chrX_+_9432980 1.248 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr16_+_89894853 1.246 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr10_+_72163860 1.246 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr4_-_25864430 1.244 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr6_-_5004238 1.242 NM_006638
RPP40
ribonuclease P/MRP 40kDa subunit
chr22_+_39745757 1.241 NM_004711
NM_145731
SYNGR1

synaptogyrin 1

chr5_-_7851255 1.239 NM_001089584
C5orf49
chromosome 5 open reading frame 49
chr8_+_144635556 1.235 NM_001166237
GSDMD
gasdermin D
chr16_+_57769667 1.233 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr14_+_67999915 1.229 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr16_-_52580805 1.226 NM_001080430
TOX3
TOX high mobility group box family member 3
chr1_+_9352955 1.225 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr22_+_45064323 1.224 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr3_+_160473995 1.223 NM_139245
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr8_-_12293895 1.221 FAM86B2
FAM86B1
family with sequence similarity 86, member B2
family with sequence similarity 86, member B1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 1.31e-16 GO:0044260 cellular macromolecule metabolic process
1.14 1.34e-14 GO:0044237 cellular metabolic process
1.16 4.49e-12 GO:0043170 macromolecule metabolic process
1.11 6.49e-11 GO:0008152 metabolic process
1.12 3.21e-10 GO:0044238 primary metabolic process
1.06 5.76e-09 GO:0009987 cellular process
1.20 1.74e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 9.89e-08 GO:0090304 nucleic acid metabolic process
1.17 1.46e-07 GO:0006807 nitrogen compound metabolic process
1.20 1.86e-07 GO:0044267 cellular protein metabolic process
1.23 2.18e-07 GO:0043412 macromolecule modification
1.23 2.43e-07 GO:0006464 protein modification process
1.17 3.05e-07 GO:0034641 cellular nitrogen compound metabolic process
1.14 6.54e-07 GO:0019222 regulation of metabolic process
1.15 1.08e-06 GO:0080090 regulation of primary metabolic process
1.15 1.26e-06 GO:0031323 regulation of cellular metabolic process
1.16 1.48e-06 GO:0060255 regulation of macromolecule metabolic process
1.31 1.20e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.09 1.74e-05 GO:0050794 regulation of cellular process
1.21 2.62e-05 GO:0016070 RNA metabolic process
1.16 6.80e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.08 9.85e-05 GO:0050789 regulation of biological process
1.16 1.01e-04 GO:0010468 regulation of gene expression
1.16 1.04e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 1.22e-04 GO:0009892 negative regulation of metabolic process
1.27 1.51e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.45 1.55e-04 GO:0016568 chromatin modification
1.28 4.09e-04 GO:0016265 death
1.15 4.11e-04 GO:0048518 positive regulation of biological process
1.27 5.00e-04 GO:0031324 negative regulation of cellular metabolic process
1.16 5.62e-04 GO:0048522 positive regulation of cellular process
1.34 5.64e-04 GO:0000902 cell morphogenesis
1.17 6.35e-04 GO:0048523 negative regulation of cellular process
1.16 6.64e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.33 7.20e-04 GO:0032989 cellular component morphogenesis
1.27 7.78e-04 GO:0008219 cell death
1.15 8.00e-04 GO:0031326 regulation of cellular biosynthetic process
1.07 9.26e-04 GO:0065007 biological regulation
1.14 9.96e-04 GO:0019538 protein metabolic process
1.15 1.21e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.14 1.30e-03 GO:0009889 regulation of biosynthetic process
1.32 1.58e-03 GO:0010629 negative regulation of gene expression
1.16 2.29e-03 GO:0051252 regulation of RNA metabolic process
1.31 2.68e-03 GO:0030030 cell projection organization
1.30 2.70e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.12 2.84e-03 GO:0071840 cellular component organization or biogenesis
1.25 3.01e-03 GO:0048468 cell development
1.27 3.22e-03 GO:0046907 intracellular transport
1.29 4.05e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.21 5.02e-03 GO:0051641 cellular localization
1.29 5.28e-03 GO:0009890 negative regulation of biosynthetic process
1.30 5.66e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.30 5.80e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 6.15e-03 GO:0051253 negative regulation of RNA metabolic process
1.28 6.88e-03 GO:0012501 programmed cell death
1.33 7.18e-03 GO:0032990 cell part morphogenesis
1.30 7.24e-03 GO:0009057 macromolecule catabolic process
1.12 7.32e-03 GO:0016043 cellular component organization
1.32 7.36e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.24 7.69e-03 GO:0022008 neurogenesis
1.28 8.27e-03 GO:0006915 apoptosis
1.17 8.72e-03 GO:0010467 gene expression
1.33 9.31e-03 GO:0048858 cell projection morphogenesis
1.13 1.04e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.24 1.18e-02 GO:0006351 transcription, DNA-dependent
1.29 1.70e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.36 1.90e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.15 1.91e-02 GO:0006355 regulation of transcription, DNA-dependent
1.17 1.98e-02 GO:0034645 cellular macromolecule biosynthetic process
1.17 2.02e-02 GO:0009059 macromolecule biosynthetic process
1.53 2.08e-02 GO:0016569 covalent chromatin modification
1.18 2.08e-02 GO:0007399 nervous system development
1.21 2.37e-02 GO:0051649 establishment of localization in cell
1.24 2.80e-02 GO:0048699 generation of neurons
1.19 3.40e-02 GO:0009893 positive regulation of metabolic process
1.14 3.42e-02 GO:0048519 negative regulation of biological process
1.13 3.52e-02 GO:0071842 cellular component organization at cellular level
1.20 3.64e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.52 3.76e-02 GO:0016570 histone modification
1.17 4.22e-02 GO:0023051 regulation of signaling
1.14 4.53e-02 GO:0048869 cellular developmental process
1.30 4.95e-02 GO:0044265 cellular macromolecule catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 2.23e-41 GO:0005622 intracellular
1.12 1.23e-38 GO:0044424 intracellular part
1.16 9.20e-37 GO:0043227 membrane-bounded organelle
1.15 3.71e-36 GO:0043231 intracellular membrane-bounded organelle
1.14 7.28e-35 GO:0043226 organelle
1.13 2.74e-34 GO:0043229 intracellular organelle
1.19 2.02e-25 GO:0005634 nucleus
1.13 1.59e-23 GO:0005737 cytoplasm
1.14 2.26e-15 GO:0044444 cytoplasmic part
1.27 3.24e-14 GO:0044428 nuclear part
1.04 3.53e-14 GO:0044464 cell part
1.04 3.99e-14 GO:0005623 cell
1.14 4.22e-12 GO:0044422 organelle part
1.14 6.59e-12 GO:0044446 intracellular organelle part
1.26 7.48e-11 GO:0031981 nuclear lumen
1.22 1.16e-09 GO:0070013 intracellular organelle lumen
1.21 3.62e-09 GO:0031974 membrane-enclosed lumen
1.21 7.22e-09 GO:0043233 organelle lumen
1.21 2.24e-08 GO:0005829 cytosol
1.26 1.57e-07 GO:0005654 nucleoplasm
1.79 7.14e-04 GO:0016585 chromatin remodeling complex
1.15 1.01e-03 GO:0031090 organelle membrane
1.27 1.58e-03 GO:0044451 nucleoplasm part
1.21 8.85e-03 GO:0005794 Golgi apparatus
1.16 9.08e-03 GO:0012505 endomembrane system
1.35 1.55e-02 GO:0005815 microtubule organizing center
1.24 2.38e-02 GO:0015630 microtubule cytoskeleton
1.23 3.54e-02 GO:0031967 organelle envelope

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 6.70e-17 GO:0005515 protein binding
1.07 2.32e-13 GO:0005488 binding
1.14 1.34e-05 GO:0003676 nucleic acid binding
1.27 5.41e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 8.54e-05 GO:0000166 nucleotide binding
1.18 4.55e-04 GO:0016740 transferase activity
1.26 1.15e-03 GO:0016301 kinase activity
1.14 1.75e-03 GO:0003677 DNA binding
1.27 3.83e-03 GO:0043565 sequence-specific DNA binding
1.32 4.21e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.32 5.72e-03 GO:0030695 GTPase regulator activity
1.17 5.90e-03 GO:0030554 adenyl nucleotide binding
1.36 6.47e-03 GO:0000988 protein binding transcription factor activity
1.36 6.47e-03 GO:0000989 transcription factor binding transcription factor activity
1.55 7.19e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.25 7.92e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.35 8.90e-03 GO:0003712 transcription cofactor activity
1.17 9.73e-03 GO:0005524 ATP binding
1.17 1.09e-02 GO:0032559 adenyl ribonucleotide binding
3.19 1.28e-02 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
1.08 1.72e-02 GO:0003824 catalytic activity
1.14 4.06e-02 GO:0017076 purine nucleotide binding
1.14 4.08e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.37 4.13e-02 GO:0005083 small GTPase regulator activity
1.19 4.48e-02 GO:0030528 transcription regulator activity