Motif ID: POU1F1.p2

Z-value: 1.021


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_873256110.374.6e-02Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_20110884 7.257 NM_001141968
NM_130785
NM_199254
TPTE2


transmembrane phosphoinositide 3-phosphatase and tensin homolog 2


chr20_+_31870940 6.807 NM_033197
BPIFB1
BPI fold containing family B, member 1
chr5_+_140220811 4.091 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr16_-_21314371 3.284 NM_001014444
NM_001888
CRYM

crystallin, mu

chr16_+_82068910 2.813 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_82068830 2.640 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_16077740 2.413 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr4_-_100273831 2.405 NM_000669
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr4_-_110723334 2.182 NM_000204
CFI
complement factor I
chr14_-_106774311 2.059 IGHA1
immunoglobulin heavy constant alpha 1
chr3_+_361365 1.894 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr6_+_32407618 1.854 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr3_+_97158453 1.714 NM_173655
EPHA6
EPH receptor A6
chr19_-_9092017 1.694 NM_024690
MUC16
mucin 16, cell surface associated
chr17_-_39165343 1.427 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr8_+_39771327 1.410 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr5_+_156696351 1.410 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_-_41213513 1.350 NM_000065
C6
complement component 6
chr6_-_32920812 1.332 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr11_-_102401430 1.331 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
11.33 1.82e-03 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
5.32 3.12e-03 GO:0060333 interferon-gamma-mediated signaling pathway
4.86 8.62e-03 GO:0071346 cellular response to interferon-gamma
4.13 4.79e-02 GO:0034341 response to interferon-gamma
3.93 9.30e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.81 2.69e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
3.10 1.49e-03 GO:0002253 activation of immune response
2.99 2.04e-02 GO:0019221 cytokine-mediated signaling pathway
2.67 2.73e-05 GO:0050776 regulation of immune response
2.64 1.10e-02 GO:0050778 positive regulation of immune response
2.57 1.80e-03 GO:0045087 innate immune response
2.30 6.27e-06 GO:0006955 immune response
2.23 2.62e-02 GO:0002684 positive regulation of immune system process
2.20 1.88e-05 GO:0006952 defense response
2.01 9.75e-03 GO:0002682 regulation of immune system process
1.85 4.24e-02 GO:0048584 positive regulation of response to stimulus
1.83 5.26e-04 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
13.75 5.20e-05 GO:0042613 MHC class II protein complex
6.02 2.88e-02 GO:0042611 MHC protein complex
1.57 4.35e-02 GO:0005887 integral to plasma membrane
1.56 4.33e-02 GO:0031226 intrinsic to plasma membrane
1.53 1.21e-03 GO:0005576 extracellular region
1.43 1.99e-02 GO:0044459 plasma membrane part
1.32 3.25e-03 GO:0071944 cell periphery
1.28 2.98e-02 GO:0005886 plasma membrane

Nothing significant found in function category.