Motif ID: POU2F1..3.p2

Z-value: 1.002


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1672982800.542.0e-03Click!
POU2F3chr11_+_1201073480.346.2e-02Click!
POU2F2chr19_-_42636559-0.029.1e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_63638343 6.411 NM_001080537
 SNTN
sentan, cilia apical structure protein
chr1_-_183622447 3.689 NM_203454
 APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr14_-_106926393 3.607 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_117160748 2.855 AKNA
AT-hook transcription factor
chr2_-_239148545 2.650 HES6
hairy and enhancer of split 6 (Drosophila)
chr9_-_75567915 2.645 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr2_-_239148626 2.603 NM_001142853
NM_018645
 HES6

hairy and enhancer of split 6 (Drosophila)

chr9_-_75568232 2.586 NM_000689
 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr18_-_53089722 2.574 NM_001243233
 TCF4
transcription factor 4
chr17_+_72732958 2.442 NM_001163989
 RAB37
RAB37, member RAS oncogene family
chr6_-_52668599 2.409 NM_145740
 GSTA1
glutathione S-transferase alpha 1
chr6_+_32407618 2.368 NM_019111
 HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_+_27062508 2.343 NM_003986
 BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr1_-_149858114 2.258 NM_003528
 HIST2H2BE
histone cluster 2, H2be
chrX_-_48776282 2.138 NM_006875
 PIM2
pim-2 oncogene
chr1_-_228645517 2.065 NM_033445
 HIST3H2A
histone cluster 3, H2a
chr6_+_26124372 1.950 NM_003512
 HIST1H2AC
histone cluster 1, H2ac
chr19_+_41430123 1.942 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr6_-_32908583 1.941 NM_002118
 HLA-DMB
major histocompatibility complex, class II, DM beta
chr16_+_3019341 1.876 NM_152341
 PAQR4
progestin and adipoQ receptor family member IV

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
9.43 3.92e-12 GO:0006334 nucleosome assembly
8.94 1.23e-11 GO:0031497 chromatin assembly
8.57 7.14e-12 GO:0065004 protein-DNA complex assembly
8.50 3.58e-11 GO:0034728 nucleosome organization
8.11 2.41e-11 GO:0071824 protein-DNA complex subunit organization
7.34 1.59e-11 GO:0006333 chromatin assembly or disassembly
7.15 3.65e-10 GO:0006323 DNA packaging
6.42 1.12e-09 GO:0071103 DNA conformation change
3.31 5.35e-05 GO:0034622 cellular macromolecular complex assembly
3.18 4.29e-06 GO:0006325 chromatin organization
2.85 1.57e-04 GO:0034621 cellular macromolecular complex subunit organization
2.67 7.97e-05 GO:0051276 chromosome organization
2.32 1.12e-03 GO:0071844 cellular component assembly at cellular level
1.85 2.19e-02 GO:0031325 positive regulation of cellular metabolic process
1.83 4.76e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.82 2.22e-02 GO:0009893 positive regulation of metabolic process
1.53 3.42e-02 GO:0048522 positive regulation of cellular process
1.52 1.73e-02 GO:0048518 positive regulation of biological process
1.51 2.71e-02 GO:0071842 cellular component organization at cellular level
1.49 3.46e-02 GO:0071841 cellular component organization or biogenesis at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
13.77 7.46e-16 GO:0000786 nucleosome
8.69 1.43e-11 GO:0032993 protein-DNA complex
4.85 1.60e-09 GO:0000785 chromatin
2.84 2.39e-06 GO:0005694 chromosome
2.82 4.75e-05 GO:0044427 chromosomal part
1.32 7.04e-04 GO:0005634 nucleus
1.11 1.98e-02 GO:0005622 intracellular
1.11 4.53e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.87 1.29e-02 GO:0001071 nucleic acid binding transcription factor activity
1.87 1.29e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.61 4.96e-04 GO:0003677 DNA binding
1.46 1.67e-03 GO:0003676 nucleic acid binding