Motif ID: POU5F1.p2

Z-value: 0.922


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_311346140.346.9e-02Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_67410825 2.344 NM_002758
 MAP2K6
mitogen-activated protein kinase kinase 6
chr20_-_7921068 2.143 NM_017545
 HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr12_-_57634474 1.902 NM_020142
 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr7_+_141463896 1.704 NM_016943
 TAS2R3
taste receptor, type 2, member 3
chr3_-_123603144 1.516 NM_053025
NM_053026
NM_053027
NM_053028
 MYLK



myosin light chain kinase



chr11_-_115088628 1.309 CADM1
cell adhesion molecule 1
chr2_-_119605758 1.291 NM_001426
 EN1
engrailed homeobox 1
chr11_-_115375065 1.284 NM_001098517
NM_014333
 CADM1

cell adhesion molecule 1

chr2_+_210444364 1.158 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr17_-_41276112 1.128 NM_007298
 BRCA1
breast cancer 1, early onset
chr8_+_26435339 1.084 NM_001386
 DPYSL2
dihydropyrimidinase-like 2
chr12_-_16757944 1.029 LMO3
LIM domain only 3 (rhombotin-like 2)
chr1_+_17575592 1.028 NM_016233
 PADI3
peptidyl arginine deiminase, type III
chr8_-_23712297 1.013 NM_003155
 STC1
stanniocalcin 1
chr13_-_60325073 1.001


chr12_+_107712151 0.961 NM_001018072
 BTBD11
BTB (POZ) domain containing 11
chr6_+_31126734 0.954 TCF19
transcription factor 19
chr10_+_91498724 0.930 KIF20B
kinesin family member 20B
chr3_+_158787040 0.923 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr12_+_7942025 0.903 NANOG
Nanog homeobox

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 102 entries
enrichment   p-value GO term description
5.24 4.88e-02 GO:0048665 neuron fate specification
4.11 1.44e-03 GO:0050909 sensory perception of taste
4.02 2.08e-03 GO:0048663 neuron fate commitment
2.41 9.40e-03 GO:0045165 cell fate commitment
2.21 3.36e-02 GO:0030900 forebrain development
1.97 5.55e-06 GO:0007417 central nervous system development
1.95 1.81e-04 GO:0007409 axonogenesis
1.90 1.59e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.88 2.50e-07 GO:0030182 neuron differentiation
1.88 6.67e-04 GO:0048812 neuron projection morphogenesis
1.88 7.33e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.87 1.60e-05 GO:0048666 neuron development
1.85 3.74e-04 GO:0031175 neuron projection development
1.85 1.39e-02 GO:0007420 brain development
1.84 2.32e-09 GO:0022008 neurogenesis
1.84 4.75e-02 GO:0007411 axon guidance
1.83 5.34e-04 GO:0032990 cell part morphogenesis
1.82 7.73e-04 GO:0048858 cell projection morphogenesis
1.80 9.93e-04 GO:0006935 chemotaxis
1.80 9.93e-04 GO:0042330 taxis

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.14 7.25e-03 GO:0030424 axon
1.82 9.38e-04 GO:0043005 neuron projection
1.52 4.95e-02 GO:0030054 cell junction
1.46 1.53e-02 GO:0042995 cell projection
1.39 7.85e-04 GO:0005856 cytoskeleton
1.38 4.20e-02 GO:0044430 cytoskeletal part
1.23 3.26e-02 GO:0043228 non-membrane-bounded organelle
1.23 3.26e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.21 2.72e-06 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
6.63 8.18e-04 GO:0008527 taste receptor activity
2.08 3.25e-05 GO:0003779 actin binding
2.01 7.38e-11 GO:0043565 sequence-specific DNA binding
1.97 4.14e-02 GO:0000975 regulatory region DNA binding
1.97 4.14e-02 GO:0001067 regulatory region nucleic acid binding
1.97 4.14e-02 GO:0044212 transcription regulatory region DNA binding
1.83 1.15e-02 GO:0016563 transcription activator activity
1.82 6.28e-11 GO:0001071 nucleic acid binding transcription factor activity
1.82 6.28e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.68 1.13e-07 GO:0030528 transcription regulator activity
1.63 9.23e-03 GO:0008092 cytoskeletal protein binding
1.34 1.09e-04 GO:0003677 DNA binding
1.22 1.19e-02 GO:0003676 nucleic acid binding
1.19 2.78e-07 GO:0005515 protein binding
1.11 5.56e-08 GO:0005488 binding