Motif ID: PRDM1.p3

Z-value: 1.234


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRDM1chr6_+_106534210-0.701.7e-05Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_29527701 11.267 NM_006398
 UBD
ubiquitin D
chr6_-_29527477 11.264 UBD
ubiquitin D
chr6_+_32821924 5.142 NM_002800
 PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr1_+_212781969 4.938 NM_001040619
NM_001206484
NM_001206488
NM_001674
 ATF3



activating transcription factor 3



chr1_+_212782103 3.959 ATF3
activating transcription factor 3
chr10_+_114135965 3.704 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114135937 3.673 NM_016234
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr22_-_36556781 3.501 NM_145640
 APOL3
apolipoprotein L, 3
chr12_+_6561176 3.132 NM_018009
 TAPBPL
TAP binding protein-like
chr10_+_114136014 3.073 ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_6659155 3.018 NM_017523
NM_199139
 XAF1

XIAP associated factor 1

chr2_+_231191877 3.003 NM_138402
 SP140L
SP140 nuclear body protein-like
chr8_+_39771327 2.703 NM_002164
 IDO1
indoleamine 2,3-dioxygenase 1
chr16_-_67970734 2.602 NM_002801
 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr8_+_144640476 2.526 NM_024736
 GSDMD
gasdermin D
chr3_-_49851356 2.386 NM_003335
 UBA7
ubiquitin-like modifier activating enzyme 7
chr4_-_46996423 2.380 NM_000809
 GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr3_-_49851217 2.334 UBA7
ubiquitin-like modifier activating enzyme 7
chr16_-_67970651 2.163 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr17_+_6659356 2.134 XAF1
XIAP associated factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
45.85 2.05e-02 GO:0002483 antigen processing and presentation of endogenous peptide antigen
45.85 2.05e-02 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
11.54 3.86e-04 GO:0006521 regulation of cellular amino acid metabolic process
10.03 1.17e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
10.03 1.17e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
10.03 1.17e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
10.03 1.17e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
10.03 1.17e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
10.03 1.17e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
10.03 1.17e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
10.03 1.17e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
9.86 1.33e-03 GO:0060337 type I interferon-mediated signaling pathway
9.86 1.33e-03 GO:0071357 cellular response to type I interferon
9.71 1.51e-03 GO:0034340 response to type I interferon
9.56 1.70e-03 GO:0033238 regulation of cellular amine metabolic process
9.56 1.70e-03 GO:0071158 positive regulation of cell cycle arrest
9.13 2.43e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
8.99 2.72e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
8.89 1.71e-04 GO:0030330 DNA damage response, signal transduction by p53 class mediator
8.74 3.40e-03 GO:0051352 negative regulation of ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
76.42 2.69e-02 GO:0071797 LUBAC complex
22.93 2.49e-05 GO:0005839 proteasome core complex
9.71 2.53e-04 GO:0000502 proteasome complex
1.48 5.11e-04 GO:0005634 nucleus
1.30 2.04e-03 GO:0043231 intracellular membrane-bounded organelle
1.29 2.19e-03 GO:0043227 membrane-bounded organelle
1.24 1.07e-02 GO:0043229 intracellular organelle
1.24 1.20e-02 GO:0043226 organelle
1.19 1.01e-02 GO:0044424 intracellular part
1.17 3.92e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
21.84 4.38e-05 GO:0004298 threonine-type endopeptidase activity
21.84 4.38e-05 GO:0070003 threonine-type peptidase activity
2.39 2.56e-03 GO:0001071 nucleic acid binding transcription factor activity
2.39 2.56e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.25 1.06e-02 GO:0030528 transcription regulator activity