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• Activity deltas table
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Motif ID: PRDM1.p3

Z-value: 1.234

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_29527701	11.267	NM_006398	UBD	ubiquitin D
chr6_-_29527477	11.264		UBD	ubiquitin D
chr6_+_32821924	5.142	NM_002800	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr1_+_212781969	4.938	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr1_+_212782103	3.959		ATF3	activating transcription factor 3
chr10_+_114135965	3.704		ACSL5	acyl-CoA synthetase long-chain family member 5
chr10_+_114135937	3.673	NM_016234	ACSL5	acyl-CoA synthetase long-chain family member 5
chr22_-_36556781	3.501	NM_145640	APOL3	apolipoprotein L, 3
chr12_+_6561176	3.132	NM_018009	TAPBPL	TAP binding protein-like
chr10_+_114136014	3.073		ACSL5	acyl-CoA synthetase long-chain family member 5
chr17_+_6659155	3.018	NM_017523 NM_199139	XAF1	XIAP associated factor 1
chr2_+_231191877	3.003	NM_138402	SP140L	SP140 nuclear body protein-like
chr8_+_39771327	2.703	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr16_-_67970734	2.602	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr8_+_144640476	2.526	NM_024736	GSDMD	gasdermin D
chr3_-_49851356	2.386	NM_003335	UBA7	ubiquitin-like modifier activating enzyme 7
chr4_-_46996423	2.380	NM_000809	GABRA4	gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr3_-_49851217	2.334		UBA7	ubiquitin-like modifier activating enzyme 7
chr16_-_67970651	2.163		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr17_+_6659356	2.134		XAF1	XIAP associated factor 1
chr3_+_51977286	2.008		PARP3	poly (ADP-ribose) polymerase family, member 3
chr1_-_217250230	1.963	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr8_-_29120571	1.949	NM_015254	KIF13B	kinesin family member 13B
chr3_+_51976274	1.835	NM_001003931 NM_005485	PARP3	poly (ADP-ribose) polymerase family, member 3
chr8_-_23540401	1.827	NM_006167	NKX3-1	NK3 homeobox 1
chr2_-_99552677	1.777	NM_207362	C2orf55	chromosome 2 open reading frame 55
chr3_-_114343052	1.764	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr6_+_126240369	1.693	NM_001199622	NCOA7	nuclear receptor coactivator 7
chr19_+_13105970	1.584	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_104159953	1.562	NM_000699	AMY2A	amylase, alpha 2A (pancreatic)
chr1_+_111889194	1.549	NM_181643	C1orf88	chromosome 1 open reading frame 88
chr18_-_53071225	1.516	NM_001243232	TCF4	transcription factor 4
chr1_-_167905078	1.500		BRP44	brain protein 44
chr15_+_71184781	1.496	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr1_-_244006885	1.442	NM_001206729	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr1_-_150738255	1.438		CTSS	cathepsin S
chr1_-_111746917	1.378		DENND2D	DENN/MADD domain containing 2D
chr10_+_92980507	1.373		PCGF5	polycomb group ring finger 5
chr11_+_63304272	1.358	NM_004585	RARRES3	retinoic acid receptor responder (tazarotene induced) 3
chr3_-_160101443	1.333	NM_001190242	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)
chr14_+_24605393	1.279		PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr17_+_41158741	1.253	NM_005533	IFI35	interferon-induced protein 35
chr5_+_73109342	1.240	NM_001244364	RGNEF	190 kDa guanine nucleotide exchange factor
chr11_-_4414887	1.227	NM_003141	TRIM21	tripartite motif containing 21
chr15_+_96876568	1.216	NM_001145157	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr3_+_113616317	1.188	NM_001172105	GRAMD1C	GRAM domain containing 1C
chr15_-_37393364	1.175	NM_001220482 NM_002399	MEIS2	Meis homeobox 2
chr5_-_96143573	1.166		ERAP1	endoplasmic reticulum aminopeptidase 1
chr17_-_4643162	1.130	NM_001100812 NM_022059	CXCL16	chemokine (C-X-C motif) ligand 16
chr11_+_64008412	1.096	NM_004470	FKBP2	FK506 binding protein 2, 13kDa
chr17_-_4642638	1.084		CXCL16	chemokine (C-X-C motif) ligand 16
chr2_-_19558371	1.070	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chrX_-_13835187	1.017		GPM6B	glycoprotein M6B
chr5_-_96143689	1.014	NM_001040458 NM_016442	ERAP1	endoplasmic reticulum aminopeptidase 1
chr8_+_96145968	1.011		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr8_+_96145942	0.988	NM_024613	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chrX_+_102883647	0.985	NM_001006640	TCEAL1	transcription elongation factor A (SII)-like 1
chr17_+_4643318	0.980	NM_001136046 NM_032265	ZMYND15	zinc finger, MYND-type containing 15
chr14_+_24605366	0.948	NM_006263 NM_176783	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_+_205410465	0.938	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr3_+_185046682	0.928		MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr10_+_91061705	0.920	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr1_-_167905214	0.919		BRP44	brain protein 44
chr1_+_222817634	0.917		MIA3	melanoma inhibitory activity family, member 3
chr20_+_13976263	0.916		MACROD2	MACRO domain containing 2
chrX_+_10124984	0.916	NM_001830	CLCN4	chloride channel 4
chr21_+_43933983	0.909		SLC37A1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr16_+_50775960	0.906	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chrX_-_118827060	0.904		SEPT6	septin 6
chr1_-_150738232	0.895		CTSS	cathepsin S
chr2_+_231280906	0.880		SP100	SP100 nuclear antigen
chr11_-_796175	0.876	NM_024698	SLC25A22	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr16_+_50776012	0.849	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr10_+_115511212	0.847	NM_001193434 NM_001193435 NM_024889	C10orf81	chromosome 10 open reading frame 81
chr8_-_79717540	0.843	NM_000880 NM_001199886 NM_001199887 NM_001199888	IL7	interleukin 7
chr5_-_75008245	0.825	NM_152408	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr6_-_130031278	0.823	NM_033515	ARHGAP18	Rho GTPase activating protein 18
chr11_-_40315663	0.819	NM_020929	LRRC4C	leucine rich repeat containing 4C
chr6_-_32811773	0.815	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr9_+_123850573	0.797	NM_007018	CNTRL	centriolin
chr2_-_152146373	0.796	NM_004688	NMI	N-myc (and STAT) interactor
chr7_-_51384331	0.778		COBL	cordon-bleu homolog (mouse)
chr2_+_231280870	0.767	NM_001080391 NM_001206701 NM_001206702 NM_001206703 NM_003113	SP100	SP100 nuclear antigen
chr2_+_231280933	0.763		SP100	SP100 nuclear antigen
chr4_+_154605421	0.749	NM_003264	TLR2	toll-like receptor 2
chr4_-_186578122	0.747	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr16_+_58283819	0.733	NM_001142302 NM_014157	CCDC113	coiled-coil domain containing 113
chr11_+_64008530	0.710	NM_001135208	FKBP2	FK506 binding protein 2, 13kDa
chr12_+_102271349	0.699		DRAM1	DNA-damage regulated autophagy modulator 1
chr19_-_23578226	0.682	NM_003430	ZNF91	zinc finger protein 91
chr2_+_202122753	0.676	NM_001080125	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr3_+_69915374	0.663	NM_198177	MITF	microphthalmia-associated transcription factor
chr20_+_13976014	0.658	NM_080676	MACROD2	MACRO domain containing 2
chr3_-_187871816	0.636		LPP-AS2	LPP antisense RNA 2 (non-protein coding)
chr4_+_146403955	0.635	NM_001003688	SMAD1	SMAD family member 1
chr7_-_105319608	0.632	NM_138495	ATXN7L1	ataxin 7-like 1
chr12_+_25205180	0.621	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr6_-_33282006	0.617	NM_003190 NM_172208 NM_172209	TAPBP	TAP binding protein (tapasin)
chr4_+_154605441	0.614		TLR2	toll-like receptor 2
chrX_+_102883891	0.612	NM_001006639 NM_004780	TCEAL1	transcription elongation factor A (SII)-like 1
chr6_+_32811895	0.609
chr6_-_33281847	0.607		TAPBP	TAP binding protein (tapasin)
chr11_+_71710971	0.576	NM_001145055	IL18BP	interleukin 18 binding protein
chr9_-_117568292	0.570	NM_005118	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chr11_-_85430117	0.567	NM_206929	SYTL2	synaptotagmin-like 2
chr10_+_91092238	0.564	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr19_-_47735858	0.555	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr10_+_92980322	0.551	NM_032373	PCGF5	polycomb group ring finger 5
chr1_-_154580677	0.549	NM_001111 NM_015840 NM_015841	ADAR	adenosine deaminase, RNA-specific
chr8_-_145060563	0.546		PARP10	poly (ADP-ribose) polymerase family, member 10
chr8_+_97657581	0.530		PGCP	plasma glutamate carboxypeptidase
chr15_+_85144219	0.529	NM_001007072 NM_017894 NM_181877	ZSCAN2	zinc finger and SCAN domain containing 2
chr6_+_26440699	0.524	NM_001242803 NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr12_+_102271082	0.524	NM_018370	DRAM1	DNA-damage regulated autophagy modulator 1
chr13_+_108921976	0.515	NM_001145645 NM_006573	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr11_+_65190267	0.514		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr7_+_89843133	0.513	NM_001040666	STEAP2	STEAP family member 2, metalloreductase
chr13_+_108922205	0.510		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr5_+_49962920	0.501		PARP8	poly (ADP-ribose) polymerase family, member 8
chrX_-_13835012	0.493		GPM6B	glycoprotein M6B
chr7_+_134832765	0.492	NM_018295	TMEM140	transmembrane protein 140
chr1_-_57045235	0.492	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr13_+_108922474	0.478		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr19_+_49977465	0.462	NM_001204502 NM_001459	FLT3LG	fms-related tyrosine kinase 3 ligand
chr18_+_55816546	0.457	NM_001144965 NM_001144968 NM_001144969 NM_001144971	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr10_+_69869249	0.456	NM_032578	MYPN	myopalladin
chr12_-_56709656	0.452		CNPY2	canopy 2 homolog (zebrafish)
chr5_+_131746579	0.451		C5orf56	chromosome 5 open reading frame 56
chr1_-_154580632	0.449		ADAR	adenosine deaminase, RNA-specific
chr16_-_73092533	0.441	NM_001164766	ZFHX3	zinc finger homeobox 3
chr14_+_73525267	0.432		RBM25	RNA binding motif protein 25
chr12_-_56709831	0.422	NM_001190991 NM_014255	CNPY2	canopy 2 homolog (zebrafish)
chr1_+_167905796	0.420	NM_001017977 NM_001198956 NM_001198957 NM_018442	DCAF6	DDB1 and CUL4 associated factor 6
chr2_-_191184770	0.419	NM_014362 NM_198047	HIBCH	3-hydroxyisobutyryl-CoA hydrolase
chr19_+_49977817	0.414	NM_001204503	FLT3LG	fms-related tyrosine kinase 3 ligand
chr12_+_51318515	0.407	NM_014033	METTL7A	methyltransferase like 7A
chr14_+_24701624	0.406	NM_001002000 NM_001002001	GMPR2	guanosine monophosphate reductase 2
chr11_+_123986103	0.398	NM_001130142 NM_014622 NM_198315	VWA5A	von Willebrand factor A domain containing 5A
chr21_-_43346780	0.394	NM_199050	C2CD2	C2 calcium-dependent domain containing 2
chr3_-_11623829	0.386	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr11_+_32112607	0.380		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr11_+_71710662	0.377	NM_001145057	IL18BP	interleukin 18 binding protein
chr22_-_36562224	0.363	NM_145641 NM_145642	APOL3	apolipoprotein L, 3
chr11_-_40314510	0.362		LRRC4C	leucine rich repeat containing 4C
chr9_+_120466607	0.357		TLR4	toll-like receptor 4
chr7_+_42971938	0.356	NM_031903	MRPL32	mitochondrial ribosomal protein L32
chr5_+_140430960	0.349	NM_013340	PCDHB1	protocadherin beta 1
chr14_+_73525187	0.347	NM_021239	RBM25	RNA binding motif protein 25
chr6_-_32812189	0.347		PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr1_+_167905921	0.341		DCAF6	DDB1 and CUL4 associated factor 6
chr1_+_2985730	0.340	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr17_+_7465284	0.338	NM_015670	SENP3	SUMO1/sentrin/SMT3 specific peptidase 3
chr1_+_162602308	0.338		DDR2	discoidin domain receptor tyrosine kinase 2
chr10_+_91087601	0.333	NM_001549	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr17_+_7465316	0.326		SENP3	SUMO1/sentrin/SMT3 specific peptidase 3
chrX_-_13835313	0.314	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr4_-_185395616	0.313	NM_002199	IRF2	interferon regulatory factor 2
chr12_+_25205488	0.309		LRMP	lymphoid-restricted membrane protein
chr3_-_8543327	0.301		LOC100288428	uncharacterized LOC100288428
chr10_+_123754141	0.299		TACC2	transforming, acidic coiled-coil containing protein 2
chr17_+_78237389	0.298
chr1_+_226012974	0.292	NM_000120	EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr7_-_42971779	0.289	NM_002787	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr20_-_18447622	0.285	NM_001099407	DZANK1	double zinc ribbon and ankyrin repeat domains 1
chr8_+_97657592	0.285		PGCP	plasma glutamate carboxypeptidase
chr14_+_58711599	0.284		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr19_-_39735606	0.275	NM_172139	IL28B	interleukin 28B (interferon, lambda 3)
chr2_+_238969730	0.274		SCLY	selenocysteine lyase
chr5_-_16617085	0.274	NM_001034850	FAM134B	family with sequence similarity 134, member B
chr1_+_161169104	0.270	NM_004550	NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr20_-_47894591	0.263	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chrX_-_13835213	0.261		GPM6B	glycoprotein M6B
chr12_-_56709777	0.246		CNPY2	canopy 2 homolog (zebrafish)
chr6_-_31704272	0.246		CLIC1	chloride intracellular channel 1
chr14_-_21493122	0.245	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr7_+_99621083	0.240		ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr22_+_22550159	0.235		IGLV6-57	immunoglobulin lambda variable 6-57
chr11_-_22647329	0.235	NM_022725	FANCF	Fanconi anemia, complementation group F
chr10_-_94003002	0.234	NM_001178137	CPEB3	cytoplasmic polyadenylation element binding protein 3
chrX_-_24045302	0.232	NM_030624	KLHL15	kelch-like 15 (Drosophila)
chr6_+_105404922	0.230	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr14_+_73525232	0.228		RBM25	RNA binding motif protein 25
chr2_-_175260349	0.227	NM_004882	CIR1	corepressor interacting with RBPJ, 1
chr1_+_101361688	0.223		SLC30A7	solute carrier family 30 (zinc transporter), member 7
chr8_-_38205652	0.221		WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1
chr21_+_26934440	0.215		MIR155HG	MIR155 host gene (non-protein coding)
chr19_-_12992249	0.213	NM_001375	DNASE2	deoxyribonuclease II, lysosomal
chr8_+_143808593	0.212	NM_016647	C8orf55	chromosome 8 open reading frame 55
chr3_+_174577069	0.212	NM_207015	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2
chr14_+_58711457	0.211	NM_002788 NM_152132	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr12_-_56223400	0.209	NM_032364	DNAJC14	DnaJ (Hsp40) homolog, subfamily C, member 14
chr14_+_58711555	0.208		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr1_-_159046555	0.208	NM_004833	AIM2	absent in melanoma 2
chr11_-_85430382	0.201	NM_001162952 NM_206930	SYTL2	synaptotagmin-like 2
chr14_-_24615794	0.200	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr1_+_151372009	0.194	NM_002796	PSMB4	proteasome (prosome, macropain) subunit, beta type, 4
chr3_-_194393205	0.193	NM_018385	LSG1	large subunit GTPase 1 homolog (S. cerevisiae)
chr2_+_238969641	0.193		SCLY	selenocysteine lyase
chr12_-_31479084	0.192		FAM60A	family with sequence similarity 60, member A
chr5_-_34043234	0.191	NM_030945 NM_181435	C1QTNF3	C1q and tumor necrosis factor related protein 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.89	1.03e-04	GO:0010605	negative regulation of macromolecule metabolic process
8.89	1.71e-04	GO:0030330	DNA damage response, signal transduction by p53 class mediator
2.76	1.77e-04	GO:0009892	negative regulation of metabolic process
11.54	3.86e-04	GO:0006521	regulation of cellular amino acid metabolic process
1.86	8.43e-04	GO:0051171	regulation of nitrogen compound metabolic process
2.73	8.68e-04	GO:0031324	negative regulation of cellular metabolic process
10.03	1.17e-03	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
10.03	1.17e-03	GO:0072395	signal transduction involved in cell cycle checkpoint
10.03	1.17e-03	GO:0072401	signal transduction involved in DNA integrity checkpoint
10.03	1.17e-03	GO:0072404	signal transduction involved in G1/S transition checkpoint
10.03	1.17e-03	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
10.03	1.17e-03	GO:0072422	signal transduction involved in DNA damage checkpoint
10.03	1.17e-03	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
10.03	1.17e-03	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
9.86	1.33e-03	GO:0060337	type I interferon-mediated signaling pathway
9.86	1.33e-03	GO:0071357	cellular response to type I interferon
7.15	1.34e-03	GO:0042770	signal transduction in response to DNA damage
9.71	1.51e-03	GO:0034340	response to type I interferon
9.56	1.70e-03	GO:0033238	regulation of cellular amine metabolic process
9.56	1.70e-03	GO:0071158	positive regulation of cell cycle arrest
1.89	2.26e-03	GO:0048522	positive regulation of cellular process
1.83	2.37e-03	GO:0048518	positive regulation of biological process
9.13	2.43e-03	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
8.99	2.72e-03	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
8.74	3.40e-03	GO:0051352	negative regulation of ligase activity
8.74	3.40e-03	GO:0051444	negative regulation of ubiquitin-protein ligase activity
8.61	3.79e-03	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.92	4.97e-03	GO:0006355	regulation of transcription, DNA-dependent
1.89	6.42e-03	GO:0051252	regulation of RNA metabolic process
7.94	7.00e-03	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.68	7.53e-03	GO:0060255	regulation of macromolecule metabolic process
7.84	7.71e-03	GO:0000216	M/G1 transition of mitotic cell cycle
7.84	7.71e-03	GO:0031575	mitotic cell cycle G1/S transition checkpoint
7.84	7.71e-03	GO:0051443	positive regulation of ubiquitin-protein ligase activity
7.84	7.71e-03	GO:0071779	G1/S transition checkpoint
2.27	8.51e-03	GO:0002376	immune system process
1.84	8.51e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
7.65	9.32e-03	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
5.75	9.54e-03	GO:0010565	regulation of cellular ketone metabolic process
1.60	9.77e-03	GO:0019222	regulation of metabolic process
1.64	1.12e-02	GO:0080090	regulation of primary metabolic process
7.46	1.12e-02	GO:0051351	positive regulation of ligase activity
7.46	1.12e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
7.03	1.74e-02	GO:0031397	negative regulation of protein ubiquitination
1.62	1.79e-02	GO:0031323	regulation of cellular metabolic process
1.79	1.79e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.77	1.95e-02	GO:0010468	regulation of gene expression
45.85	2.05e-02	GO:0002483	antigen processing and presentation of endogenous peptide antigen
45.85	2.05e-02	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
6.80	2.23e-02	GO:0051438	regulation of ubiquitin-protein ligase activity
1.35	2.27e-02	GO:0050789	regulation of biological process
6.51	3.06e-02	GO:0051340	regulation of ligase activity
1.73	3.20e-02	GO:0031326	regulation of cellular biosynthetic process
2.81	3.25e-02	GO:0010629	negative regulation of gene expression
3.43	3.53e-02	GO:0044419	interspecies interaction between organisms
4.93	3.61e-02	GO:0031400	negative regulation of protein modification process
1.36	3.66e-02	GO:0050794	regulation of cellular process
1.71	4.36e-02	GO:0009889	regulation of biosynthetic process
3.55	4.42e-02	GO:0051098	regulation of binding

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
22.93	2.49e-05	GO:0005839	proteasome core complex
9.71	2.53e-04	GO:0000502	proteasome complex
1.48	5.11e-04	GO:0005634	nucleus
1.30	2.04e-03	GO:0043231	intracellular membrane-bounded organelle
1.29	2.19e-03	GO:0043227	membrane-bounded organelle
1.19	1.01e-02	GO:0044424	intracellular part
1.24	1.07e-02	GO:0043229	intracellular organelle
1.24	1.20e-02	GO:0043226	organelle
76.42	2.69e-02	GO:0071797	LUBAC complex
1.17	3.92e-02	GO:0005622	intracellular

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
21.84	4.38e-05	GO:0004298	threonine-type endopeptidase activity
21.84	4.38e-05	GO:0070003	threonine-type peptidase activity
2.39	2.56e-03	GO:0001071	nucleic acid binding transcription factor activity
2.39	2.56e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
2.25	1.06e-02	GO:0030528	transcription regulator activity