Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 15.688


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX2chr19_-_61105610.993.7e-26Click!
RFX3chr9_-_35257210.961.7e-16Click!
RFXAPchr13_+_373933060.632.2e-04Click!
RFX1chr19_-_14116875-0.441.4e-02Click!
RFX4chr12_+_1069949140.356.2e-02Click!
RFX5chr1_-_1513196740.281.3e-01Click!
RFXANKchr19_+_19303732-0.057.9e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_23487512 194.236 NM_004914
RAB36
RAB36, member RAS oncogene family
chr21_-_43916298 193.525 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr17_-_74137370 167.329 NM_001454
FOXJ1
forkhead box J1
chr1_-_109656478 165.076 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr16_-_67427335 154.861 NM_015964
NM_016140
TPPP3

tubulin polymerization-promoting protein family member 3

chr1_-_159869897 132.868 NM_012337
CCDC19
coiled-coil domain containing 19
chr3_-_197676755 128.550 NM_001134435
IQCG
IQ motif containing G
chr15_+_71184781 110.112 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chrX_-_48693934 109.756 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chrX_+_106449861 103.397 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr1_+_111889194 103.314 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr9_+_127615695 100.863 NM_001045476
WDR38
WD repeat domain 38
chr11_+_94245694 100.740 NM_001190462
LOC643037
uncharacterized LOC643037
chr17_-_6735007 99.342 NM_053285
TEKT1
tektin 1
chr6_+_88117689 96.984 NM_001031743
C6orf165
chromosome 6 open reading frame 165
chr2_+_228736326 95.595 NM_178821
WDR69
WD repeat domain 69
chr10_+_63422718 92.434 NM_173554
C10orf107
chromosome 10 open reading frame 107
chr11_+_111385509 91.175 NM_001100388
NM_207430
C11orf88

chromosome 11 open reading frame 88

chr6_+_43612766 88.839 NM_001193341
NM_152732
RSPH9

radial spoke head 9 homolog (Chlamydomonas)

chr3_-_50383009 88.790 NM_015896
ZMYND10
zinc finger, MYND-type containing 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
10.61 2.60e-09 GO:0042384 cilium assembly
8.15 5.48e-08 GO:0060271 cilium morphogenesis
5.91 1.06e-05 GO:0010927 cellular component assembly involved in morphogenesis
5.04 4.68e-05 GO:0030031 cell projection assembly
3.44 4.09e-02 GO:0007018 microtubule-based movement
2.76 2.72e-03 GO:0007017 microtubule-based process
1.36 1.82e-02 GO:XXXXXXX unannotated

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
12.74 4.06e-02 GO:0034464 BBSome
11.76 1.36e-03 GO:0060170 cilium membrane
10.07 4.86e-11 GO:0005932 microtubule basal body
9.32 4.95e-09 GO:0035085 cilium axoneme
8.78 7.69e-12 GO:0005930 axoneme
7.96 6.54e-11 GO:0044441 cilium part
7.78 2.21e-05 GO:0030286 dynein complex
6.06 1.31e-17 GO:0005929 cilium
5.54 2.62e-03 GO:0019861 flagellum
3.52 2.16e-02 GO:0005875 microtubule associated complex
3.47 6.43e-09 GO:0005874 microtubule
2.81 3.05e-07 GO:0044463 cell projection part
2.68 5.22e-03 GO:0005813 centrosome
2.64 1.43e-10 GO:0015630 microtubule cytoskeleton
2.60 1.72e-04 GO:0005815 microtubule organizing center
2.09 2.74e-06 GO:0042995 cell projection
1.79 4.92e-04 GO:0044430 cytoskeletal part
1.73 6.73e-04 GO:XXXXXXX unannotated
1.54 9.55e-03 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
4.19 8.90e-03 GO:0003777 microtubule motor activity
3.28 3.44e-03 GO:0003774 motor activity