Motif ID: RUNX1..3.p2

Z-value: 1.109


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX3chr1_-_252914740.495.6e-03Click!
RUNX2chr6_+_45389818-0.402.8e-02Click!
RUNX1chr21_-_36260086-0.173.6e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_29641068 2.421 EVI2B
ecotropic viral integration site 2B
chr2_-_216300770 1.933 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr20_-_23967431 1.874 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr3_+_100328432 1.841 NM_032787
GPR128
G protein-coupled receptor 128
chr7_+_37723378 1.528


chr8_+_39771327 1.432 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr22_+_22988781 1.326 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr3_-_150920946 1.320 NM_013308
GPR171
G protein-coupled receptor 171
chr17_+_56232493 1.280 NM_012374
OR4D1
olfactory receptor, family 4, subfamily D, member 1
chr3_-_71179736 1.073 FOXP1
forkhead box P1
chr19_+_56989482 1.060 LOC100128252
uncharacterized LOC100128252
chr17_+_9745847 1.016 GLP2R
glucagon-like peptide 2 receptor
chr12_+_15125955 0.994 NM_006205
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr17_-_29641094 0.972 NM_006495
EVI2B
ecotropic viral integration site 2B
chr2_-_216300444 0.953 FN1
fibronectin 1
chr19_-_41356193 0.953 NM_000762
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr13_+_113741668 0.923 MCF2L
MCF.2 cell line derived transforming sequence-like
chr2_-_216241321 0.898 FN1
fibronectin 1
chr14_+_24540742 0.884 NM_006032
CPNE6
copine VI (neuronal)
chr15_-_93631751 0.860 NM_001166287
RGMA
RGM domain family, member A
chr15_-_93632161 0.859 NM_020211
RGMA
RGM domain family, member A
chr1_+_196621007 0.854 NM_000186
NM_001014975
CFH

complement factor H

chr14_+_75988765 0.820 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75988838 0.794 BATF
basic leucine zipper transcription factor, ATF-like
chr6_+_30104509 0.750 NM_138700
TRIM40
tripartite motif containing 40
chr9_+_120466607 0.746 TLR4
toll-like receptor 4
chr13_-_114538953 0.744 NM_001143945
GAS6
growth arrest-specific 6
chr4_-_174450529 0.741 HAND2
heart and neural crest derivatives expressed 2
chr6_-_32163299 0.740 NM_022107
GPSM3
G-protein signaling modulator 3
chr1_+_172628157 0.731 NM_000639
FASLG
Fas ligand (TNF superfamily, member 6)
chr19_-_6720585 0.705 NM_000064
C3
complement component 3
chr8_+_144295067 0.683 NM_178172
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr5_-_44388666 0.671 NM_004465
FGF10
fibroblast growth factor 10
chr14_+_60975937 0.665 NM_007374
SIX6
SIX homeobox 6
chr17_-_34524054 0.665 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr5_-_149535420 0.664 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr20_+_16728997 0.661 NM_020157
OTOR
otoraplin
chr9_-_70429730 0.654 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr9_-_70178814 0.636 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr11_-_124190092 0.629 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr9_+_42717233 0.628 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr1_-_25291474 0.627 NM_001031680
RUNX3
runt-related transcription factor 3
chrX_-_78623006 0.625 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr11_-_5345530 0.623 NM_033180
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr12_-_114846191 0.617 NM_000192
NM_080717
TBX5

T-box 5

chr6_-_46047978 0.612 NM_001114086
CLIC5
chloride intracellular channel 5
chr2_+_169659099 0.611 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr4_-_10686314 0.609 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr7_+_120628867 0.591 C7orf58
chromosome 7 open reading frame 58
chr1_-_168513201 0.589 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr1_+_26485510 0.585 NM_024869
FAM110D
family with sequence similarity 110, member D
chr4_+_88896868 0.583 SPP1
secreted phosphoprotein 1
chr1_+_218518675 0.581 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr11_-_62457001 0.566 LRRN4CL
LRRN4 C-terminal like
chr1_-_161039586 0.560 ARHGAP30
Rho GTPase activating protein 30
chr7_+_120628722 0.559 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr1_-_161039649 0.547 ARHGAP30
Rho GTPase activating protein 30
chr2_+_202671197 0.545 NM_139158
CDK15
cyclin-dependent kinase 15
chr17_-_43045612 0.544 NM_006688
C1QL1
complement component 1, q subcomponent-like 1
chrX_-_49121171 0.539 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr21_+_31768294 0.538 NM_181599
KRTAP13-1
keratin associated protein 13-1
chrX_+_48542159 0.533 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_+_124481451 0.530 NM_052959
PANX3
pannexin 3
chr19_+_50015535 0.528 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_56989549 0.525 LOC100128252
uncharacterized LOC100128252
chr2_-_158300517 0.524 NM_004288
CYTIP
cytohesin 1 interacting protein
chr4_+_88896899 0.522 SPP1
secreted phosphoprotein 1
chr8_-_110620220 0.520 SYBU
syntabulin (syntaxin-interacting)
chr11_+_71710971 0.519 NM_001145055
IL18BP
interleukin 18 binding protein
chr10_+_91092238 0.514 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_-_34417386 0.514 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr13_-_46756295 0.514 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr8_+_1952875 0.514 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr17_-_29641087 0.513 EVI2B
ecotropic viral integration site 2B
chr22_+_25003610 0.510 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr16_+_72088507 0.509 NM_001126102
NM_005143
HP

haptoglobin

chr11_-_121986800 0.506 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr17_-_1532109 0.506 NM_152346
SLC43A2
solute carrier family 43, member 2
chr4_+_88896801 0.505 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr1_-_161039703 0.503 ARHGAP30
Rho GTPase activating protein 30
chrX_+_49160124 0.499 NM_001098413
GAGE10
G antigen 10
chr4_+_88896838 0.497 SPP1
secreted phosphoprotein 1
chr1_+_32930638 0.495 NM_001145720
ZBTB8B
zinc finger and BTB domain containing 8B
chr19_+_41430123 0.493 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr11_-_58345593 0.478 NM_001143995
LPXN
leupaxin
chr7_+_27135672 0.470 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr1_+_156211950 0.453 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr10_+_114154522 0.450 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_50015868 0.449 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr12_-_58026846 0.449 NM_001478
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr1_-_161039745 0.447 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr17_+_80317122 0.445 NM_207459
TEX19
testis expressed 19
chr19_+_51226638 0.444 CLEC11A
C-type lectin domain family 11, member A
chr6_-_32013806 0.443 NM_032470
TNXB
tenascin XB
chr2_+_128175989 0.441 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_-_73840495 0.440 UNC13D
unc-13 homolog D (C. elegans)
chr3_-_45267068 0.437 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr17_-_39183453 0.434 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr6_-_46889620 0.433 NM_001098518
GPR116
G protein-coupled receptor 116
chr5_-_137071462 0.423 KLHL3
kelch-like 3 (Drosophila)
chr20_+_54987167 0.420 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr18_+_61575203 0.419 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_+_133495925 0.416 TF
transferrin
chr8_+_24151579 0.410 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chrX_-_112066353 0.410 NM_001113490
AMOT
angiomotin
chr11_+_71710662 0.407 NM_001145057
IL18BP
interleukin 18 binding protein
chr8_-_60031545 0.407 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr19_+_41497182 0.404 NM_000767
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_-_161039413 0.394 ARHGAP30
Rho GTPase activating protein 30
chr10_-_105238996 0.393 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr8_-_12973752 0.391 NM_001164271
DLC1
deleted in liver cancer 1
chr7_+_150690838 0.389 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr12_+_54410641 0.387 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr6_+_31543340 0.387 NM_000594
TNF
tumor necrosis factor
chr17_-_1531543 0.387 SLC43A2
solute carrier family 43, member 2
chr4_+_89299874 0.381 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr1_+_20617411 0.380 NM_001039500
VWA5B1
von Willebrand factor A domain containing 5B1
chr11_+_124095343 0.380 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chr11_-_10715297 0.380 MRVI1
murine retrovirus integration site 1 homolog
chr4_+_8951476 0.376 NM_001040071
LOC650293
seven transmembrane helix receptor
chr4_+_646965 0.375 NM_001145292
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr5_-_180018465 0.372 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr7_+_100183926 0.371 NM_033506
FBXO24
F-box protein 24
chr1_+_159796478 0.370 NM_020125
SLAMF8
SLAM family member 8
chr1_-_184006491 0.368 GLT25D2
glycosyltransferase 25 domain containing 2
chrX_+_119005733 0.367 NM_004541
NDUFA1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
chr17_+_1633754 0.367 WDR81
WD repeat domain 81
chr17_-_56606710 0.366 NM_004574
SEPT4
septin 4
chr1_+_156339002 0.366 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr5_-_76934508 0.362 NM_032109
OTP
orthopedia homeobox
chr17_+_32582295 0.361 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr3_-_147124595 0.361 NM_001243256
NM_032153
ZIC4

Zic family member 4

chr6_+_25279765 0.358 LRRC16A
leucine rich repeat containing 16A
chr6_-_134498973 0.356 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_71781091 0.355 NUMA1
nuclear mitotic apparatus protein 1
chr11_-_62457370 0.355 NM_203422
LRRN4CL
LRRN4 C-terminal like
chr1_-_11188800 0.354


chr5_+_147258273 0.353 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr17_+_47288068 0.351 ABI3
ABI family, member 3
chr3_+_15643451 0.351 BTD
biotinidase
chr12_-_14849427 0.349 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr8_+_85095702 0.348 RALYL
RALY RNA binding protein-like
chr1_+_22303417 0.347 NM_007352
CELA3A
CELA3B
chymotrypsin-like elastase family, member 3A
chymotrypsin-like elastase family, member 3B
chr1_+_152850797 0.347 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein
chr6_-_52109226 0.346 NM_052872
IL17F
interleukin 17F
chr5_+_140174443 0.344 NM_018905
NM_031495
PCDHA2

protocadherin alpha 2

chr2_-_29297126 0.344 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr19_+_50796820 0.342 MYH14
myosin, heavy chain 14, non-muscle
chr2_-_217724781 0.341 NM_003284
TNP1
transition protein 1 (during histone to protamine replacement)
chr17_+_40274755 0.340 NM_033194
HSPB9
heat shock protein, alpha-crystallin-related, B9
chr5_+_156696351 0.338 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr6_+_31539875 0.337 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr3_-_40350948 0.336 FLJ33065
uncharacterized LOC440952
chr2_-_234652623 0.331 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr19_+_15052298 0.330 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chrX_-_128788913 0.330 NM_017413
APLN
apelin
chr7_+_2552162 0.328 NM_001166355
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_4754275 0.328 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr6_-_31846751 0.327 SLC44A4
solute carrier family 44, member 4
chr16_+_53133063 0.326 CHD9
chromodomain helicase DNA binding protein 9
chr11_+_76745434 0.325 NM_138706
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr15_-_26961911 0.323 NM_001191320
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr15_-_50558161 0.322 NM_002112
HDC
histidine decarboxylase
chr5_-_176326314 0.320 NM_002115
HK3
hexokinase 3 (white cell)
chr22_-_37975937 0.320 NM_006498
LGALS2
lectin, galactoside-binding, soluble, 2
chr16_-_1922161 0.318 NM_001163560
C16orf73
chromosome 16 open reading frame 73
chr12_-_54121203 0.317 NM_001143682
NM_020898
CALCOCO1

calcium binding and coiled-coil domain 1

chr2_-_74756823 0.317 AUP1
ancient ubiquitous protein 1
chr1_+_84864214 0.316 NM_021233
DNASE2B
deoxyribonuclease II beta
chr7_+_150745604 0.314 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr17_+_44076615 0.311 NM_001007532
STH
saitohin
chr15_+_50647105 0.310 LOC100129387
uncharacterized LOC100129387
chr2_+_128176019 0.310 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chrX_-_145896248 0.308 NM_001144064
NM_001244892
CXorf51A
CXorf51B
chromosome X open reading frame 51A
chromosome X open reading frame 51B
chr5_+_35856990 0.305 NM_002185
IL7R
interleukin 7 receptor
chr6_-_31846766 0.304 SLC44A4
solute carrier family 44, member 4
chr12_+_13349716 0.302 EMP1
epithelial membrane protein 1
chr20_-_45985411 0.301 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr5_-_108063960 0.301 HP07349
uncharacterized protein HP07349
chr9_-_69202203 0.301 NM_001085476
FOXD4L6
forkhead box D4-like 6
chr19_-_54761057 0.299 NM_001081442
NM_001081443
NM_006840
LILRB5


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5


chr6_+_25279651 0.299 NM_001173977
NM_017640
LRRC16A

leucine rich repeat containing 16A

chr19_-_49567123 0.298 NM_006179
NTF4
neurotrophin 4
chr17_-_10276321 0.298 NM_003802
MYH13
myosin, heavy chain 13, skeletal muscle
chr6_+_31540092 0.297 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr8_+_21900389 0.297 NM_003867
FGF17
fibroblast growth factor 17
chrX_+_145891301 0.294 NM_001144064
NM_001244892
CXorf51A
CXorf51B
chromosome X open reading frame 51A
chromosome X open reading frame 51B
chr2_-_74756815 0.291 AUP1
ancient ubiquitous protein 1
chr12_-_8693391 0.290 NM_014358
CLEC4E
C-type lectin domain family 4, member E
chr4_-_76928601 0.289 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr3_-_10547267 0.288 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr8_-_146078355 0.287 COMMD5
COMM domain containing 5
chr22_+_31003069 0.287 NM_000355
NM_001184726
TCN2

transcobalamin II

chr2_+_204732509 0.285 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr9_+_120466625 0.284 TLR4
toll-like receptor 4
chr3_-_187454247 0.283 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr21_-_36421586 0.283 NM_001754
RUNX1
runt-related transcription factor 1
chr11_+_67222817 0.278 NM_145200
CABP4
calcium binding protein 4
chr6_-_30525370 0.277 NM_005275
GNL1
guanine nucleotide binding protein-like 1
chr3_+_25470067 0.277 RARB
retinoic acid receptor, beta

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 3.65e-16 GO:0002376 immune system process
1.94 7.82e-09 GO:0006955 immune response
1.25 9.06e-09 GO:0050896 response to stimulus
1.36 1.81e-08 GO:0023052 signaling
1.35 4.36e-07 GO:0007165 signal transduction
1.39 6.31e-07 GO:0048731 system development
1.88 8.55e-07 GO:0002682 regulation of immune system process
1.38 3.96e-06 GO:0048518 positive regulation of biological process
1.49 4.88e-06 GO:0007166 cell surface receptor linked signaling pathway
1.43 6.96e-06 GO:0065008 regulation of biological quality
1.28 1.35e-05 GO:0051716 cellular response to stimulus
1.97 1.48e-05 GO:0001775 cell activation
1.24 1.50e-05 GO:0032501 multicellular organismal process
1.17 2.21e-05 GO:0065007 biological regulation
1.33 3.38e-05 GO:0048856 anatomical structure development
2.31 4.04e-05 GO:0048534 hemopoietic or lymphoid organ development
1.72 4.14e-05 GO:0048584 positive regulation of response to stimulus
1.55 4.50e-05 GO:0051239 regulation of multicellular organismal process
1.64 5.08e-05 GO:0009605 response to external stimulus
1.90 7.75e-05 GO:0008284 positive regulation of cell proliferation
1.30 8.83e-05 GO:0007275 multicellular organismal development
1.63 9.98e-05 GO:0042127 regulation of cell proliferation
1.43 1.33e-04 GO:0048583 regulation of response to stimulus
1.17 1.41e-04 GO:0050789 regulation of biological process
2.18 2.06e-04 GO:0002520 immune system development
1.64 2.10e-04 GO:0009611 response to wounding
1.68 5.92e-04 GO:0007267 cell-cell signaling
1.89 9.57e-04 GO:0002684 positive regulation of immune system process
1.55 1.57e-03 GO:0007154 cell communication
1.33 2.13e-03 GO:0048522 positive regulation of cellular process
2.18 2.92e-03 GO:0030097 hemopoiesis
1.16 3.53e-03 GO:0050794 regulation of cellular process
1.43 4.20e-03 GO:0009653 anatomical structure morphogenesis
3.69 4.37e-03 GO:0002761 regulation of myeloid leukocyte differentiation
1.24 5.59e-03 GO:0032502 developmental process
1.57 6.11e-03 GO:0040011 locomotion
1.32 6.36e-03 GO:0048519 negative regulation of biological process
1.36 6.46e-03 GO:0048513 organ development
1.75 8.09e-03 GO:0006935 chemotaxis
1.75 8.09e-03 GO:0042330 taxis
2.16 8.68e-03 GO:0002253 activation of immune response
2.08 9.53e-03 GO:0050865 regulation of cell activation
2.17 1.06e-02 GO:0051249 regulation of lymphocyte activation
3.11 1.08e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
2.24 1.16e-02 GO:0046649 lymphocyte activation
1.79 1.22e-02 GO:0050776 regulation of immune response
1.99 1.23e-02 GO:0050778 positive regulation of immune response
1.59 1.26e-02 GO:2000026 regulation of multicellular organismal development
1.49 1.58e-02 GO:0042981 regulation of apoptosis
3.92 1.62e-02 GO:0048145 regulation of fibroblast proliferation
3.02 1.69e-02 GO:0002250 adaptive immune response
1.89 1.87e-02 GO:0051240 positive regulation of multicellular organismal process
1.48 1.95e-02 GO:0010941 regulation of cell death
2.07 2.02e-02 GO:0002694 regulation of leukocyte activation
1.48 2.39e-02 GO:0043067 regulation of programmed cell death
1.54 3.09e-02 GO:0006952 defense response
1.52 3.11e-02 GO:0042592 homeostatic process
1.38 4.78e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.52 8.23e-10 GO:0005576 extracellular region
1.87 3.84e-09 GO:0005615 extracellular space
1.71 2.96e-08 GO:0044421 extracellular region part
1.63 4.46e-08 GO:0031226 intrinsic to plasma membrane
1.61 2.11e-07 GO:0005887 integral to plasma membrane
1.41 1.22e-06 GO:0044459 plasma membrane part
2.58 2.94e-04 GO:0009897 external side of plasma membrane
1.18 1.27e-03 GO:0031224 intrinsic to membrane
1.18 1.70e-03 GO:0016021 integral to membrane
1.21 1.77e-03 GO:0005886 plasma membrane
1.15 2.62e-03 GO:0044425 membrane part
1.20 3.33e-03 GO:0071944 cell periphery
1.79 4.44e-03 GO:0009986 cell surface
1.13 5.76e-03 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.31 3.82e-04 GO:0003823 antigen binding
2.31 4.02e-04 GO:0005125 cytokine activity
2.36 4.38e-04 GO:0005126 cytokine receptor binding
1.53 4.73e-04 GO:0005102 receptor binding
1.35 7.75e-03 GO:0004872 receptor activity
9.57 1.80e-02 GO:0003840 gamma-glutamyltransferase activity
1.29 2.13e-02 GO:0004871 signal transducer activity
1.29 2.13e-02 GO:0060089 molecular transducer activity