Motif ID: SMAD1..7,9.p2

Z-value: 2.105


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD9chr13_-_37494370-0.742.9e-06Click!
SMAD3chr15_+_673581940.675.4e-05Click!
SMAD4chr18_+_48556483-0.667.7e-05Click!
SMAD1chr4_+_146403955-0.622.9e-04Click!
SMAD2chr18_-_45457454-0.551.7e-03Click!
SMAD6chr15_+_67000929-0.384.1e-02Click!
SMAD7chr18_-_464757020.291.2e-01Click!
SMAD5chr5_+_1354685380.077.3e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_48328601 15.040 NM_033518
 SLC38A5
solute carrier family 38, member 5
chrX_-_48328564 9.589 SLC38A5
solute carrier family 38, member 5
chr5_-_151066445 9.460 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_50349811 8.748 NM_153281
 HYAL1
hyaluronoglucosaminidase 1
chr19_-_51472816 7.422 NM_002774
 KLK6
kallikrein-related peptidase 6
chr12_-_47473424 6.925 NM_001143668
NM_181847
 AMIGO2

adhesion molecule with Ig-like domain 2

chr5_-_151066492 6.682 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr19_-_36019194 6.592 NM_001166034
NM_001166035
NM_198538
 SBSN


suprabasin


chr17_+_70117154 6.271 NM_000346
 SOX9
SRY (sex determining region Y)-box 9
chr11_-_125366048 6.157 NM_005103
NM_022549
 FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr22_+_38035683 6.116 NM_018957
 SH3BP1
SH3-domain binding protein 1
chr7_+_134464417 5.691 CALD1
caldesmon 1
chr19_-_11689591 5.409 NM_001111034
 ACP5
acid phosphatase 5, tartrate resistant
chr1_-_6445737 5.339 NM_181864
 ACOT7
acyl-CoA thioesterase 7
chrX_-_106959597 4.987 NM_001015881
 TSC22D3
TSC22 domain family, member 3
chr15_-_90039776 4.877 NM_016321
 RHCG
Rh family, C glycoprotein
chr9_+_35673852 4.818 NM_001216
 CA9
carbonic anhydrase IX
chr9_-_123639566 4.776 NM_001009936
NM_015651
 PHF19

PHD finger protein 19

chr9_-_139890984 4.739 NM_004669
 CLIC3
chloride intracellular channel 3
chr19_-_44285012 4.704 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 100 entries
enrichment   p-value GO term description
6.45 4.07e-03 GO:0048880 sensory system development
6.45 4.07e-03 GO:0048892 lateral line nerve development
6.45 4.07e-03 GO:0048895 lateral line nerve glial cell differentiation
6.45 4.07e-03 GO:0048925 lateral line system development
6.45 4.07e-03 GO:0048937 lateral line nerve glial cell development
6.45 4.07e-03 GO:0050935 iridophore differentiation
6.35 2.62e-02 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
5.45 1.05e-02 GO:0048846 axon extension involved in axon guidance
5.32 1.08e-03 GO:0030513 positive regulation of BMP signaling pathway
5.32 1.08e-03 GO:0048484 enteric nervous system development
3.76 1.20e-02 GO:0048483 autonomic nervous system development
3.55 7.44e-05 GO:0007422 peripheral nervous system development
3.43 5.73e-03 GO:0021675 nerve development
3.42 1.24e-02 GO:0014032 neural crest cell development
3.25 1.46e-02 GO:0014033 neural crest cell differentiation
3.03 8.11e-03 GO:0060560 developmental growth involved in morphogenesis
2.26 2.03e-02 GO:0061138 morphogenesis of a branching epithelium
2.22 2.36e-03 GO:0048589 developmental growth
2.14 2.03e-02 GO:0001763 morphogenesis of a branching structure
1.94 1.49e-02 GO:0006874 cellular calcium ion homeostasis

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.27 3.22e-03 GO:0005925 focal adhesion
2.16 9.75e-03 GO:0005924 cell-substrate adherens junction
2.15 8.24e-03 GO:0030055 cell-substrate junction
2.14 2.56e-04 GO:0005912 adherens junction
2.11 1.30e-04 GO:0070161 anchoring junction
1.79 4.29e-02 GO:0031252 cell leading edge
1.78 4.79e-04 GO:0015629 actin cytoskeleton
1.50 2.21e-03 GO:0030054 cell junction
1.39 8.40e-03 GO:0005626 insoluble fraction
1.31 3.10e-02 GO:0000267 cell fraction
1.25 1.08e-03 GO:0044459 plasma membrane part
1.23 2.00e-02 GO:0005829 cytosol
1.16 5.55e-03 GO:0071944 cell periphery
1.15 1.65e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.78 2.23e-04 GO:0003779 actin binding
1.64 3.89e-05 GO:0008092 cytoskeletal protein binding
1.17 7.21e-09 GO:0005515 protein binding