Motif ID: SOX17.p2

Z-value: 1.437


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_553704940.658.8e-05Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_8113862 6.970 NM_004217
 AURKB
aurora kinase B
chr1_+_151032866 6.699 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_68462948 6.514 CCNB1
cyclin B1
chr1_+_151032880 6.261 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr20_+_37554954 5.762 NM_030919
 FAM83D
family with sequence similarity 83, member D
chr10_+_102106958 5.701 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr2_+_27008881 5.270 NM_001809
NM_001042426
 CENPA

centromere protein A

chr3_-_52567708 5.248 NM_001134231
 NT5DC2
5'-nucleotidase domain containing 2
chr20_+_37555055 5.198 FAM83D
family with sequence similarity 83, member D
chr10_+_102106771 5.137 NM_005063
 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr3_-_52567809 5.136 NT5DC2
5'-nucleotidase domain containing 2
chr11_-_66725790 5.080 NM_000920
NM_001040716
 PC

pyruvate carboxylase

chr1_+_151032683 5.046 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_-_26232890 4.950 NM_001145454
NM_005563
 STMN1

stathmin 1

chr10_+_102107074 4.902 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_-_26232643 4.897 NM_203401
 STMN1
stathmin 1
chr5_+_68462985 4.870 CCNB1
cyclin B1
chr7_-_27135524 4.755 NM_005522
NM_153620
 HOXA1

homeobox A1

chr7_+_27135672 4.730 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr2_+_27008912 4.691 CENPA
centromere protein A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
2.50 1.40e-02 GO:0006334 nucleosome assembly
2.37 4.13e-02 GO:0031497 chromatin assembly
2.34 3.83e-02 GO:0034728 nucleosome organization
2.33 2.90e-02 GO:0065004 protein-DNA complex assembly
2.28 3.24e-02 GO:0071824 protein-DNA complex subunit organization
1.64 4.05e-02 GO:0007409 axonogenesis
1.62 4.33e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.52 1.20e-02 GO:0030182 neuron differentiation
1.49 1.91e-02 GO:0071844 cellular component assembly at cellular level
1.47 1.33e-02 GO:0051128 regulation of cellular component organization
1.45 9.57e-03 GO:0048468 cell development
1.44 1.54e-02 GO:0022008 neurogenesis
1.43 2.83e-05 GO:0007399 nervous system development
1.43 4.67e-02 GO:0048699 generation of neurons
1.40 2.39e-02 GO:0022607 cellular component assembly
1.38 5.91e-06 GO:0030154 cell differentiation
1.36 2.00e-05 GO:0048869 cellular developmental process
1.32 1.49e-06 GO:0048731 system development
1.32 4.62e-02 GO:0009653 anatomical structure morphogenesis
1.31 7.28e-08 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.98 1.09e-03 GO:0000786 nucleosome
2.33 1.23e-02 GO:0032993 protein-DNA complex
1.67 3.94e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.54 1.23e-02 GO:0008092 cytoskeletal protein binding
1.14 9.76e-05 GO:0005515 protein binding