Motif ID: SOX2.p2

Z-value: 1.557


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_181430075-0.824.1e-08Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153029987 12.999 NM_005988
 SPRR2A
small proline-rich protein 2A
chr1_-_153044083 9.089 NM_001017418
 SPRR2B
small proline-rich protein 2B
chr1_+_171154387 7.786 NM_001460
 FMO2
flavin containing monooxygenase 2 (non-functional)
chr1_+_84647342 7.166 NM_001242862
 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_-_161056762 6.283 ITGB6
integrin, beta 6
chr1_-_153085963 5.128 NM_001014450
 SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr2_+_102508333 4.996 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_-_26205437 4.924 NM_002254
 KIF3C
kinesin family member 3C
chr7_+_26400503 4.872 NM_001199837
 SNX10
sorting nexin 10
chr7_-_41742666 4.810 NM_002192
 INHBA
inhibin, beta A
chr1_-_153013593 4.744 NM_006945
 SPRR2D
small proline-rich protein 2D
chr7_+_134464417 4.734 CALD1
caldesmon 1
chr7_-_83824216 4.357 NM_006080
 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_-_26205327 4.345 KIF3C
kinesin family member 3C
chr8_-_124553253 3.904 FBXO32
F-box protein 32
chr2_+_102314162 3.893 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
 MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr12_-_67072881 3.889 NM_001178074
NM_021150
 GRIP1

glutamate receptor interacting protein 1

chr6_+_114178516 3.778 NM_002356
 MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_+_32504250 3.651 NM_013959
 NRG1
neuregulin 1
chr7_+_134464372 3.534 CALD1
caldesmon 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
2.02 2.36e-02 GO:0034330 cell junction organization
1.88 2.44e-05 GO:0007411 axon guidance
1.81 5.26e-06 GO:0007409 axonogenesis
1.79 5.26e-06 GO:0048812 neuron projection morphogenesis
1.78 8.74e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.77 5.33e-03 GO:0030029 actin filament-based process
1.74 4.72e-06 GO:0000904 cell morphogenesis involved in differentiation
1.72 2.06e-05 GO:0031175 neuron projection development
1.62 1.45e-04 GO:0048666 neuron development
1.62 6.57e-04 GO:0032990 cell part morphogenesis
1.62 7.84e-04 GO:0048858 cell projection morphogenesis
1.60 2.07e-04 GO:0000902 cell morphogenesis
1.60 1.43e-03 GO:0006935 chemotaxis
1.60 1.43e-03 GO:0042330 taxis
1.58 6.23e-03 GO:0007010 cytoskeleton organization
1.57 5.41e-05 GO:0030182 neuron differentiation
1.57 4.07e-04 GO:0032989 cellular component morphogenesis
1.52 1.42e-05 GO:0022008 neurogenesis
1.50 8.31e-05 GO:0040011 locomotion
1.50 1.18e-04 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.08 4.71e-02 GO:0032432 actin filament bundle
2.08 1.12e-02 GO:0044420 extracellular matrix part
1.91 1.44e-02 GO:0005912 adherens junction
1.90 3.49e-03 GO:0030424 axon
1.85 1.60e-02 GO:0070161 anchoring junction
1.67 6.29e-03 GO:0015629 actin cytoskeleton
1.60 1.77e-02 GO:0005578 proteinaceous extracellular matrix
1.52 4.71e-02 GO:0031012 extracellular matrix
1.48 2.54e-03 GO:0030054 cell junction
1.28 3.49e-03 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.05 7.61e-04 GO:0005070 SH3/SH2 adaptor activity
2.61 9.26e-03 GO:0035591 signaling adaptor activity
2.09 9.45e-03 GO:0030674 protein binding, bridging
2.02 1.75e-02 GO:0060090 binding, bridging
1.70 1.60e-03 GO:0003779 actin binding
1.64 1.25e-05 GO:0008092 cytoskeletal protein binding
1.52 7.15e-04 GO:0005198 structural molecule activity
1.11 3.61e-04 GO:0005515 protein binding