Motif ID: SPI1.p2

Z-value: 1.183


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_47400096-0.542.2e-03Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_51504799 4.574 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr19_-_36019194 3.583 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr19_-_51472003 3.385 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr19_+_35645614 3.186 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_25101993 3.044 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr6_-_30652434 3.034 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_+_35645640 3.021 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr6_-_30654978 2.956 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr9_-_107690526 2.685 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_-_30654406 2.647 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr20_+_3776905 2.616 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr19_-_51456159 2.608 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr15_+_63335086 2.573 TPM1
tropomyosin 1 (alpha)
chr1_+_150480584 2.528 ECM1
extracellular matrix protein 1
chr15_+_67358161 2.528 SMAD3
SMAD family member 3
chr12_+_41086189 2.491 NM_001843
NM_175038
CNTN1

contactin 1

chr12_-_25101923 2.474 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_-_39219578 2.378 NM_001465
NM_199335
FYB

FYN binding protein

chr4_+_8200918 2.373 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr19_-_51472816 2.281 NM_002774
KLK6
kallikrein-related peptidase 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 119 entries
enrichment   p-value GO term description
2.36 4.46e-02 GO:0007044 cell-substrate junction assembly
1.81 4.95e-02 GO:0002576 platelet degranulation
1.74 2.77e-03 GO:0007265 Ras protein signal transduction
1.56 4.09e-02 GO:0051272 positive regulation of cellular component movement
1.49 1.44e-07 GO:0007599 hemostasis
1.48 2.56e-07 GO:0007596 blood coagulation
1.48 2.56e-07 GO:0050817 coagulation
1.48 2.42e-03 GO:0051270 regulation of cellular component movement
1.47 2.81e-02 GO:0030168 platelet activation
1.47 3.32e-02 GO:0032101 regulation of response to external stimulus
1.45 6.10e-08 GO:0042060 wound healing
1.45 3.61e-07 GO:0006928 cellular component movement
1.45 3.02e-02 GO:0030334 regulation of cell migration
1.45 3.22e-02 GO:2000145 regulation of cell motility
1.43 1.28e-06 GO:0050878 regulation of body fluid levels
1.43 3.34e-04 GO:0016477 cell migration
1.43 1.93e-02 GO:0030029 actin filament-based process
1.43 2.26e-02 GO:0040012 regulation of locomotion
1.40 4.82e-02 GO:0032940 secretion by cell
1.39 1.04e-09 GO:0009611 response to wounding

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.62 2.45e-02 GO:0030055 cell-substrate junction
1.62 3.50e-02 GO:0005924 cell-substrate adherens junction
1.55 1.54e-03 GO:0031252 cell leading edge
1.53 2.07e-02 GO:0005912 adherens junction
1.48 1.18e-04 GO:0015629 actin cytoskeleton
1.32 1.20e-02 GO:0005768 endosome
1.31 3.91e-02 GO:0043005 neuron projection
1.25 2.61e-03 GO:0005626 insoluble fraction
1.23 1.81e-02 GO:0005624 membrane fraction
1.21 7.69e-08 GO:0044459 plasma membrane part
1.21 1.35e-07 GO:0005829 cytosol
1.21 5.78e-04 GO:0031226 intrinsic to plasma membrane
1.21 7.21e-04 GO:0005887 integral to plasma membrane
1.21 3.29e-03 GO:0000267 cell fraction
1.18 3.34e-03 GO:0005856 cytoskeleton
1.13 2.77e-03 GO:0043234 protein complex
1.11 4.84e-13 GO:0005737 cytoplasm
1.11 3.03e-03 GO:0032991 macromolecular complex
1.10 9.29e-03 GO:0071944 cell periphery
1.09 1.69e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.52 2.54e-04 GO:0005096 GTPase activator activity
1.48 7.02e-05 GO:0016563 transcription activator activity
1.43 7.57e-05 GO:0008047 enzyme activator activity
1.43 9.50e-04 GO:0003779 actin binding
1.42 1.47e-02 GO:0032403 protein complex binding
1.39 8.65e-06 GO:0008092 cytoskeletal protein binding
1.33 4.56e-05 GO:0043565 sequence-specific DNA binding
1.33 1.21e-02 GO:0019904 protein domain specific binding
1.32 3.90e-05 GO:0019899 enzyme binding
1.31 3.36e-02 GO:0042803 protein homodimerization activity
1.29 4.60e-04 GO:0042802 identical protein binding
1.29 7.02e-03 GO:0004672 protein kinase activity
1.27 1.05e-02 GO:0046983 protein dimerization activity
1.25 5.18e-04 GO:0030528 transcription regulator activity
1.20 1.34e-38 GO:0005515 protein binding
1.08 6.54e-20 GO:0005488 binding