Motif ID: SPI1.p2

Z-value: 1.183


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_47400096-0.542.2e-03Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51504799 4.574 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr19_-_36019194 3.583 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr19_-_51472003 3.385 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr19_+_35645614 3.186 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_25101993 3.044 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr6_-_30652434 3.034 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_+_35645640 3.021 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr6_-_30654978 2.956 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr9_-_107690526 2.685 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr6_-_30654406 2.647 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr20_+_3776905 2.616 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr19_-_51456159 2.608 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr15_+_63335086 2.573 TPM1
tropomyosin 1 (alpha)
chr1_+_150480584 2.528 ECM1
extracellular matrix protein 1
chr15_+_67358161 2.528 SMAD3
SMAD family member 3
chr12_+_41086189 2.491 NM_001843
NM_175038
CNTN1

contactin 1

chr12_-_25101923 2.474 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr5_-_39219578 2.378 NM_001465
NM_199335
FYB

FYN binding protein

chr4_+_8200918 2.373 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr19_-_51472816 2.281 NM_002774
KLK6
kallikrein-related peptidase 6
chr7_-_100860991 2.206 NM_001084
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr7_+_27135672 2.201 HOTAIRM1
HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr2_+_31456879 2.197 NM_014600
EHD3
EH-domain containing 3
chr17_-_45933138 2.188 NM_199262
SP6
Sp6 transcription factor
chr18_+_56338818 2.186 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr17_+_1959512 2.142 NM_001098202
HIC1
hypermethylated in cancer 1
chr10_-_5541401 2.118 NM_017422
CALML5
calmodulin-like 5
chr17_+_65373574 2.108 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_+_35646006 1.908 FXYD5
FXYD domain containing ion transport regulator 5
chr7_-_100860865 1.905 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_72374919 1.861 NM_019885
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr7_-_100860841 1.842 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr12_+_107712151 1.794 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr5_-_172755195 1.789 STC2
stanniocalcin 2
chr12_+_53443834 1.764 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_118827007 1.754 NM_006760
UPK2
uroplakin 2
chrX_-_15872905 1.734


chr2_-_65659634 1.690 NM_181784
SPRED2
sprouty-related, EVH1 domain containing 2
chr18_+_21452981 1.644 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr10_-_135090325 1.627 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr6_+_86159301 1.623 NM_001204813
NM_002526
NT5E

5'-nucleotidase, ecto (CD73)

chr20_-_23030141 1.613 NM_000361
THBD
thrombomodulin
chr1_+_230202966 1.604 GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr11_-_66725790 1.588 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr18_+_56338783 1.540 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_-_159923961 1.516 NM_001146172
NM_001146173
NM_033438
SLAMF9


SLAM family member 9


chr2_-_238322840 1.497 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr2_-_65659115 1.484 SPRED2
sprouty-related, EVH1 domain containing 2
chr6_+_43738757 1.475 VEGFA
vascular endothelial growth factor A
chr6_-_30655078 1.471 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_-_8642232 1.452 MYO1F
myosin IF
chr7_+_18126543 1.440 NM_001204144
HDAC9
histone deacetylase 9
chr2_-_113542970 1.439 NM_000575
IL1A
interleukin 1, alpha
chr7_-_130353561 1.439 COPG2
coatomer protein complex, subunit gamma 2
chr7_-_130353579 1.436 NM_012133
COPG2
coatomer protein complex, subunit gamma 2
chr1_+_17531619 1.424 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr2_-_238322770 1.415 COL6A3
collagen, type VI, alpha 3
chr2_-_238322815 1.393 COL6A3
collagen, type VI, alpha 3
chrX_+_135278912 1.390 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chrX_-_47489243 1.387 NM_001145252
CFP
complement factor properdin
chr18_+_56338678 1.387 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr11_+_61595633 1.380 NM_004265
FADS2
fatty acid desaturase 2
chr17_-_41623652 1.377 NM_001079675
ETV4
ets variant 4
chr9_+_34653911 1.372 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chrX_-_15872921 1.366 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr12_-_123466195 1.361 ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_-_197115566 1.352 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_+_74120092 1.345 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr12_-_54785018 1.336 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr12_+_96588000 1.331 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr17_+_7210929 1.331 EIF5A
eukaryotic translation initiation factor 5A
chr5_-_39270708 1.325 NM_001243093
FYB
FYN binding protein
chr4_-_111119752 1.308 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr1_+_32050510 1.288 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr7_-_107643330 1.285 NM_002291
LAMB1
laminin, beta 1
chr15_+_67358194 1.284 NM_005902
SMAD3
SMAD family member 3
chr22_+_31489343 1.283 SMTN
smoothelin
chr8_+_22022644 1.276 NM_001199
NM_006129
BMP1

bone morphogenetic protein 1

chr11_-_58343308 1.271 NM_004811
LPXN
leupaxin
chr2_-_31361284 1.270 GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr7_-_100860719 1.263 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr11_-_64647136 1.262 EHD1
EH-domain containing 1
chr2_+_74120132 1.255 ACTG2
actin, gamma 2, smooth muscle, enteric
chr9_+_128509616 1.240 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr12_+_96588254 1.231 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_-_37193609 1.225 NM_003162
STRN
striatin, calmodulin binding protein
chr19_+_48828820 1.215 EMP3
epithelial membrane protein 3
chr8_+_22022677 1.214 BMP1
bone morphogenetic protein 1
chr17_-_41623246 1.198 NM_001986
ETV4
ets variant 4
chr7_+_106505696 1.185 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_-_6479880 1.168 NM_019089
HES2
hairy and enhancer of split 2 (Drosophila)
chr11_-_2160199 1.158 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_+_23690190 1.157 PLK1
polo-like kinase 1
chr11_-_112034671 1.140 NM_001243211
NM_001562
IL18

interleukin 18 (interferon-gamma-inducing factor)

chr6_+_74405764 1.137 CD109
CD109 molecule
chr6_-_32160637 1.135 GPSM3
G-protein signaling modulator 3
chr1_-_20812271 1.133 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr7_-_100860615 1.132 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr1_+_8384389 1.127 NM_001080397
SLC45A1
solute carrier family 45, member 1
chr1_+_154300275 1.118 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr11_+_61595772 1.111 FADS2
fatty acid desaturase 2
chr5_-_127873734 1.105 NM_001999
FBN2
fibrillin 2
chr20_+_361272 1.096 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr1_-_231175971 1.094 NM_198552
FAM89A
family with sequence similarity 89, member A
chr7_-_130353490 1.087 COPG2
coatomer protein complex, subunit gamma 2
chr1_-_155948934 1.080 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr20_+_33759773 1.076 NM_006404
PROCR
protein C receptor, endothelial
chr16_+_23690191 1.076 NM_005030
PLK1
polo-like kinase 1
chr17_-_36413177 1.067 LOC440434
aminopeptidase puromycin sensitive pseudogene
chr22_-_37640187 1.067 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_+_79472851 1.057 ANXA3
annexin A3
chr11_+_2920910 1.057 NM_183233
SLC22A18
solute carrier family 22, member 18
chr6_+_86159738 1.045 NT5E
5'-nucleotidase, ecto (CD73)
chr9_-_101017492 1.043 TBC1D2
TBC1 domain family, member 2
chr11_+_1861431 1.042 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr12_-_48152860 1.039 NM_001098531
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr6_+_37137882 1.034 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr7_+_100797685 1.033 NM_001283
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr8_-_10587942 1.027 NM_031439
SOX7
SRY (sex determining region Y)-box 7
chr20_+_3776385 1.027 NM_004358
NM_021872
NM_021873
CDC25B


cell division cycle 25 homolog B (S. pombe)


chr12_-_49365545 1.023 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr9_+_74526369 1.021 NM_182505
C9orf85
chromosome 9 open reading frame 85
chr12_-_109915127 1.013 NM_031954
KCTD10
potassium channel tetramerisation domain containing 10
chr19_+_48828627 1.011 NM_001425
EMP3
epithelial membrane protein 3
chrX_-_47489703 1.008 NM_002621
CFP
complement factor properdin
chr12_-_48152180 0.985 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr14_+_55034633 0.982 SAMD4A
sterile alpha motif domain containing 4A
chr15_+_63334753 0.979 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chrX_-_119694492 0.979 CUL4B
cullin 4B
chr11_+_129245834 0.979 NM_003658
BARX2
BARX homeobox 2
chr2_-_70780621 0.974 TGFA
transforming growth factor, alpha
chr12_-_72057676 0.972 NM_144982
ZFC3H1
zinc finger, C3H1-type containing
chr5_+_86563594 0.968 RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr5_-_140998480 0.966 DIAPH1
diaphanous homolog 1 (Drosophila)
chr19_-_36004553 0.960 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr17_+_2699731 0.958 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr15_+_90744506 0.956 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr2_-_30144431 0.953 NM_004304
ALK
anaplastic lymphoma receptor tyrosine kinase
chr4_+_79472741 0.950 NM_005139
ANXA3
annexin A3
chr15_+_93443559 0.948 CHD2
chromodomain helicase DNA binding protein 2
chr17_-_7155258 0.943 NM_015343
CTDNEP1
CTD nuclear envelope phosphatase 1
chr8_+_25316736 0.937 CDCA2
cell division cycle associated 2
chr1_-_159915382 0.931 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr6_-_75994496 0.930 TMEM30A
transmembrane protein 30A
chr16_+_23690160 0.929 PLK1
polo-like kinase 1
chr9_+_34990715 0.920 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chrX_+_99899388 0.920 SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_155959860 0.918 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr17_-_26903854 0.917 ALDOC
aldolase C, fructose-bisphosphate
chr16_+_14726828 0.916 BFAR
bifunctional apoptosis regulator
chr17_-_39768939 0.915 NM_005557
KRT16
keratin 16
chr12_-_120687956 0.912 NM_025157
PXN
paxillin
chr17_+_65373362 0.911 PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr20_-_44540685 0.905 PLTP
phospholipid transfer protein
chr9_-_107690336 0.904 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_57232859 0.899 NM_018304
PRR11
proline rich 11
chr1_-_168106535 0.898 GPR161
G protein-coupled receptor 161
chr15_+_38544119 0.893 SPRED1
sprouty-related, EVH1 domain containing 1
chr2_-_228029274 0.890 NM_000092
COL4A4
collagen, type IV, alpha 4
chr3_+_50654589 0.890 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr16_-_74734687 0.889 NM_001142497
NM_152649
MLKL

mixed lineage kinase domain-like

chr16_+_83986826 0.889 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr9_-_114937464 0.881 NM_022486
SUSD1
sushi domain containing 1
chr1_+_155178489 0.879 NM_002455
NM_198883
MTX1

metaxin 1

chr10_+_75673346 0.874 PLAU
plasminogen activator, urokinase
chr16_+_30194730 0.873 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr7_-_23509972 0.872 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr10_-_33623978 0.868 NRP1
neuropilin 1
chr12_-_53600999 0.867 NM_000889
ITGB7
integrin, beta 7
chr5_-_172755418 0.865 STC2
stanniocalcin 2
chr16_+_23690234 0.865 PLK1
polo-like kinase 1
chrX_-_40594663 0.862 MED14
mediator complex subunit 14
chr11_+_72980938 0.860 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr12_+_1800146 0.856 ADIPOR2
adiponectin receptor 2
chr6_+_43543877 0.856 NM_006502
POLH
polymerase (DNA directed), eta
chr5_+_135364583 0.843 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr22_+_38453478 0.841 PICK1
protein interacting with PRKCA 1
chr5_-_140013034 0.841 NM_000591
CD14
CD14 molecule
chr3_-_111851967 0.838 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr17_+_25621105 0.835 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr5_-_72744351 0.832 NM_004472
FOXD1
forkhead box D1
chr4_-_143767603 0.827 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr6_-_43595079 0.823 GTPBP2
GTP binding protein 2
chrX_+_48367346 0.822 NM_022825
NM_203473
PORCN

porcupine homolog (Drosophila)

chr6_-_112575880 0.820 LAMA4
laminin, alpha 4
chr14_+_68086633 0.816 ARG2
arginase, type II
chr5_+_92918924 0.813 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_49716970 0.812 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr11_+_130184326 0.810 FLJ34521
uncharacterized LOC646383
chr1_-_209957872 0.808 NM_152485
C1orf74
chromosome 1 open reading frame 74
chr17_-_74497406 0.804 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr3_-_48130633 0.804 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr11_-_31832784 0.801 PAX6
paired box 6
chr17_+_1958354 0.796 NM_006497
HIC1
hypermethylated in cancer 1
chr19_+_16187047 0.793 NM_003290
TPM4
tropomyosin 4
chr7_-_99698278 0.792 NM_182776
MCM7
minichromosome maintenance complex component 7
chr7_-_98030165 0.789 BAIAP2L1
BAI1-associated protein 2-like 1
chr1_-_153363544 0.789 NM_002964
S100A8
S100 calcium binding protein A8
chr17_-_62657997 0.788 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr5_+_86564044 0.787 NM_002890
RASA1
RAS p21 protein activator (GTPase activating protein) 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.11 2.49e-27 GO:0009987 cellular process
1.14 6.27e-21 GO:0065007 biological regulation
1.15 9.43e-17 GO:0050794 regulation of cellular process
1.14 1.17e-16 GO:0050789 regulation of biological process
1.22 3.94e-16 GO:0023052 signaling
1.19 5.85e-14 GO:0051716 cellular response to stimulus
1.22 7.31e-14 GO:0007165 signal transduction
1.24 1.27e-12 GO:0048518 positive regulation of biological process
1.23 4.61e-12 GO:0048731 system development
1.20 1.72e-11 GO:0007275 multicellular organismal development
1.21 2.50e-11 GO:0048856 anatomical structure development
1.24 3.16e-11 GO:0048522 positive regulation of cellular process
1.18 4.06e-10 GO:0032502 developmental process
1.39 1.04e-09 GO:0009611 response to wounding
1.26 1.99e-09 GO:0048583 regulation of response to stimulus
1.22 2.16e-08 GO:0048519 negative regulation of biological process
1.23 3.88e-08 GO:0065008 regulation of biological quality
1.29 5.26e-08 GO:0035556 intracellular signal transduction
1.45 6.10e-08 GO:0042060 wound healing
1.26 8.97e-08 GO:0023051 regulation of signaling
1.12 1.07e-07 GO:0050896 response to stimulus
1.49 1.44e-07 GO:0007599 hemostasis
1.21 1.49e-07 GO:0006950 response to stress
1.29 1.69e-07 GO:0051239 regulation of multicellular organismal process
1.48 2.56e-07 GO:0007596 blood coagulation
1.48 2.56e-07 GO:0050817 coagulation
1.45 3.61e-07 GO:0006928 cellular component movement
1.27 5.58e-07 GO:0009966 regulation of signal transduction
1.13 5.95e-07 GO:0043170 macromolecule metabolic process
1.33 6.34e-07 GO:0032879 regulation of localization
1.23 8.53e-07 GO:0048513 organ development
1.43 1.28e-06 GO:0050878 regulation of body fluid levels
1.21 2.73e-06 GO:0048523 negative regulation of cellular process
1.36 4.80e-06 GO:0016192 vesicle-mediated transport
1.34 4.86e-06 GO:0040011 locomotion
1.21 8.00e-06 GO:0030154 cell differentiation
1.15 1.00e-05 GO:0051179 localization
1.13 1.07e-05 GO:0044260 cellular macromolecule metabolic process
1.15 1.33e-05 GO:0016043 cellular component organization
1.20 1.41e-05 GO:0048869 cellular developmental process
1.29 2.69e-05 GO:0010646 regulation of cell communication
1.29 4.80e-05 GO:0009605 response to external stimulus
1.14 5.53e-05 GO:0071840 cellular component organization or biogenesis
1.35 7.59e-05 GO:0019220 regulation of phosphate metabolic process
1.35 7.59e-05 GO:0051174 regulation of phosphorus metabolic process
1.25 8.79e-05 GO:0002376 immune system process
1.25 9.15e-05 GO:0051641 cellular localization
1.28 1.16e-04 GO:0007154 cell communication
1.23 1.31e-04 GO:0009653 anatomical structure morphogenesis
1.20 1.54e-04 GO:0007166 cell surface receptor linked signaling pathway
1.34 1.70e-04 GO:0042325 regulation of phosphorylation
1.09 1.75e-04 GO:0044238 primary metabolic process
1.18 1.83e-04 GO:0042221 response to chemical stimulus
1.25 2.18e-04 GO:0050790 regulation of catalytic activity
1.23 2.30e-04 GO:0065009 regulation of molecular function
1.28 2.56e-04 GO:0042127 regulation of cell proliferation
1.30 2.82e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.22 3.20e-04 GO:0007399 nervous system development
1.43 3.34e-04 GO:0016477 cell migration
1.39 3.47e-04 GO:0001775 cell activation
1.25 5.24e-04 GO:0051649 establishment of localization in cell
1.31 6.17e-04 GO:0007267 cell-cell signaling
1.34 7.10e-04 GO:0001932 regulation of protein phosphorylation
1.28 7.30e-04 GO:0050793 regulation of developmental process
1.10 7.74e-04 GO:0032501 multicellular organismal process
1.29 7.92e-04 GO:0009891 positive regulation of biosynthetic process
1.24 8.19e-04 GO:0031325 positive regulation of cellular metabolic process
1.30 1.20e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.23 1.20e-03 GO:0009893 positive regulation of metabolic process
1.14 1.41e-03 GO:0019538 protein metabolic process
1.18 2.31e-03 GO:0006464 protein modification process
1.09 2.36e-03 GO:0044237 cellular metabolic process
1.48 2.42e-03 GO:0051270 regulation of cellular component movement
1.38 2.55e-03 GO:0048870 cell motility
1.38 2.55e-03 GO:0051674 localization of cell
1.35 2.76e-03 GO:0008284 positive regulation of cell proliferation
1.74 2.77e-03 GO:0007265 Ras protein signal transduction
1.39 3.29e-03 GO:0007243 intracellular protein kinase cascade
1.39 3.29e-03 GO:0023014 signal transduction via phosphorylation event
1.26 3.44e-03 GO:0022008 neurogenesis
1.25 3.58e-03 GO:0006793 phosphorus metabolic process
1.25 3.58e-03 GO:0006796 phosphate metabolic process
1.25 3.62e-03 GO:0032268 regulation of cellular protein metabolic process
1.28 3.78e-03 GO:0031399 regulation of protein modification process
1.29 3.79e-03 GO:0051049 regulation of transport
1.29 3.79e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 4.05e-03 GO:0006468 protein phosphorylation
1.24 4.32e-03 GO:0051246 regulation of protein metabolic process
1.15 4.91e-03 GO:0071842 cellular component organization at cellular level
1.23 6.24e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.27 6.60e-03 GO:0048584 positive regulation of response to stimulus
1.37 8.06e-03 GO:0007268 synaptic transmission
1.15 9.05e-03 GO:0044267 cellular protein metabolic process
1.34 9.47e-03 GO:0019226 transmission of nerve impulse
1.34 9.47e-03 GO:0035637 multicellular organismal signaling
1.26 1.00e-02 GO:0051128 regulation of cellular component organization
1.14 1.39e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.29 1.39e-02 GO:0051254 positive regulation of RNA metabolic process
1.29 1.43e-02 GO:0010628 positive regulation of gene expression
1.25 1.56e-02 GO:0048699 generation of neurons
1.27 1.81e-02 GO:2000026 regulation of multicellular organismal development
1.43 1.93e-02 GO:0030029 actin filament-based process
1.33 2.06e-02 GO:0006935 chemotaxis
1.33 2.06e-02 GO:0042330 taxis
1.43 2.26e-02 GO:0040012 regulation of locomotion
1.47 2.81e-02 GO:0030168 platelet activation
1.45 3.02e-02 GO:0030334 regulation of cell migration
1.45 3.22e-02 GO:2000145 regulation of cell motility
1.47 3.32e-02 GO:0032101 regulation of response to external stimulus
1.07 3.55e-02 GO:0008152 metabolic process
1.33 3.85e-02 GO:0045859 regulation of protein kinase activity
1.27 3.93e-02 GO:0043085 positive regulation of catalytic activity
1.56 4.09e-02 GO:0051272 positive regulation of cellular component movement
1.32 4.39e-02 GO:0043549 regulation of kinase activity
2.36 4.46e-02 GO:0007044 cell-substrate junction assembly
1.32 4.66e-02 GO:0048585 negative regulation of response to stimulus
1.40 4.82e-02 GO:0032940 secretion by cell
1.81 4.95e-02 GO:0002576 platelet degranulation
1.12 4.96e-02 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 4.84e-13 GO:0005737 cytoplasm
1.06 3.36e-09 GO:0044424 intracellular part
1.06 8.65e-09 GO:0005622 intracellular
1.21 7.69e-08 GO:0044459 plasma membrane part
1.21 1.35e-07 GO:0005829 cytosol
1.48 1.18e-04 GO:0015629 actin cytoskeleton
1.21 5.78e-04 GO:0031226 intrinsic to plasma membrane
1.21 7.21e-04 GO:0005887 integral to plasma membrane
1.03 1.45e-03 GO:0005623 cell
1.55 1.54e-03 GO:0031252 cell leading edge
1.03 1.72e-03 GO:0044464 cell part
1.08 1.81e-03 GO:0044444 cytoplasmic part
1.08 2.34e-03 GO:0044422 organelle part
1.25 2.61e-03 GO:0005626 insoluble fraction
1.13 2.77e-03 GO:0043234 protein complex
1.11 3.03e-03 GO:0032991 macromolecular complex
1.21 3.29e-03 GO:0000267 cell fraction
1.18 3.34e-03 GO:0005856 cytoskeleton
1.08 3.71e-03 GO:0044446 intracellular organelle part
1.10 9.29e-03 GO:0071944 cell periphery
1.32 1.20e-02 GO:0005768 endosome
1.09 1.69e-02 GO:0005886 plasma membrane
1.23 1.81e-02 GO:0005624 membrane fraction
1.53 2.07e-02 GO:0005912 adherens junction
1.62 2.45e-02 GO:0030055 cell-substrate junction
1.62 3.50e-02 GO:0005924 cell-substrate adherens junction
1.31 3.91e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 1.34e-38 GO:0005515 protein binding
1.08 6.54e-20 GO:0005488 binding
1.39 8.65e-06 GO:0008092 cytoskeletal protein binding
1.32 3.90e-05 GO:0019899 enzyme binding
1.33 4.56e-05 GO:0043565 sequence-specific DNA binding
1.48 7.02e-05 GO:0016563 transcription activator activity
1.43 7.57e-05 GO:0008047 enzyme activator activity
1.52 2.54e-04 GO:0005096 GTPase activator activity
1.29 4.60e-04 GO:0042802 identical protein binding
1.25 5.18e-04 GO:0030528 transcription regulator activity
1.43 9.50e-04 GO:0003779 actin binding
1.29 7.02e-03 GO:0004672 protein kinase activity
1.27 1.05e-02 GO:0046983 protein dimerization activity
1.33 1.21e-02 GO:0019904 protein domain specific binding
1.42 1.47e-02 GO:0032403 protein complex binding
1.31 3.36e-02 GO:0042803 protein homodimerization activity