Motif ID: SPIB.p2

Z-value: 1.942


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_509221940.144.7e-01Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_113885145 9.707 IL1RN
interleukin 1 receptor antagonist
chr2_+_113885137 9.342 NM_173842
 IL1RN
interleukin 1 receptor antagonist
chr19_-_51472003 8.288 NM_001012964
NM_001012965
 KLK6

kallikrein-related peptidase 6

chr19_-_51472816 7.289 NM_002774
 KLK6
kallikrein-related peptidase 6
chr12_+_4382882 6.274 NM_001759
 CCND2
cyclin D2
chr10_+_102107074 5.677 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr10_+_102107001 5.274 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_40610940 4.953 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr10_+_102107256 4.754


chr17_+_40610897 4.693 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_40610875 4.648 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr12_-_89746238 4.583 DUSP6
dual specificity phosphatase 6
chr17_+_2699731 4.569 NM_001100398
NM_015085
 RAP1GAP2

RAP1 GTPase activating protein 2

chr19_+_35645614 4.290 NM_014164
 FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_89745997 4.220 DUSP6
dual specificity phosphatase 6
chr12_-_89746244 4.200 NM_001946
NM_022652
 DUSP6

dual specificity phosphatase 6

chr19_-_41859253 4.179 TGFB1
transforming growth factor, beta 1
chr17_+_40610905 4.165 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr17_+_40610857 4.083 NM_001130020
NM_001130021
NM_005177
 ATP6V0A1


ATPase, H+ transporting, lysosomal V0 subunit a1


chr10_+_102106958 3.958 SCD
stearoyl-CoA desaturase (delta-9-desaturase)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 67 entries
enrichment   p-value GO term description
2.09 3.39e-03 GO:0002576 platelet degranulation
1.99 1.35e-03 GO:0043241 protein complex disassembly
1.99 1.35e-03 GO:0043624 cellular protein complex disassembly
1.98 9.15e-03 GO:0019080 viral genome expression
1.98 9.15e-03 GO:0019083 viral transcription
1.96 5.94e-04 GO:0032984 macromolecular complex disassembly
1.96 5.94e-04 GO:0034623 cellular macromolecular complex disassembly
1.96 9.74e-03 GO:0006415 translational termination
1.89 1.16e-02 GO:0006414 translational elongation
1.81 6.15e-04 GO:0050900 leukocyte migration
1.76 1.79e-04 GO:0022411 cellular component disassembly
1.76 1.79e-04 GO:0071845 cellular component disassembly at cellular level
1.65 1.04e-05 GO:0006412 translation
1.61 5.57e-09 GO:0007599 hemostasis
1.61 5.83e-09 GO:0007596 blood coagulation
1.61 5.83e-09 GO:0050817 coagulation
1.57 1.47e-02 GO:0030168 platelet activation
1.55 1.63e-08 GO:0042060 wound healing
1.51 8.76e-07 GO:0050878 regulation of body fluid levels
1.49 3.12e-02 GO:0030029 actin filament-based process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
2.28 3.47e-03 GO:0031093 platelet alpha granule lumen
2.23 5.82e-03 GO:0034774 secretory granule lumen
2.17 2.65e-03 GO:0031091 platelet alpha granule
2.14 1.53e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.06 3.69e-02 GO:0031983 vesicle lumen
1.91 5.65e-03 GO:0030027 lamellipodium
1.89 2.74e-02 GO:0022626 cytosolic ribosome
1.61 5.39e-03 GO:0031252 cell leading edge
1.58 4.60e-05 GO:0015629 actin cytoskeleton
1.58 1.04e-02 GO:0005840 ribosome
1.40 4.34e-02 GO:0044433 cytoplasmic vesicle part
1.32 3.50e-02 GO:0030529 ribonucleoprotein complex
1.30 6.78e-12 GO:0005829 cytosol
1.16 6.78e-03 GO:0044459 plasma membrane part
1.15 4.65e-03 GO:0043228 non-membrane-bounded organelle
1.15 4.65e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.14 4.73e-04 GO:0032991 macromolecular complex
1.12 1.98e-06 GO:0044444 cytoplasmic part
1.09 9.21e-07 GO:0005737 cytoplasm
1.05 9.95e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.68 9.27e-03 GO:0003735 structural constituent of ribosome
1.51 8.63e-04 GO:0003779 actin binding
1.39 2.47e-04 GO:0005198 structural molecule activity
1.33 2.09e-02 GO:0008092 cytoskeletal protein binding
1.32 6.88e-04 GO:0003723 RNA binding
1.28 2.08e-02 GO:0042802 identical protein binding
1.25 1.32e-02 GO:0005102 receptor binding
1.18 7.33e-24 GO:0005515 protein binding
1.08 2.09e-12 GO:0005488 binding