Motif ID: SPZ1.p2

Z-value: 1.404


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_796157890.487.8e-03Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_125133322 2.772 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_76425207 2.492 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr1_-_20812271 2.300 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_+_37137882 2.283 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr20_+_33759773 2.227 NM_006404
 PROCR
protein C receptor, endothelial
chr18_-_28681885 2.193 NM_004949
NM_024422
 DSC2

desmocollin 2

chr4_+_75480628 2.190 NM_001657
 AREG
amphiregulin
chr12_+_41086189 2.131 NM_001843
NM_175038
 CNTN1

contactin 1

chr4_+_75310852 2.029 NM_001657
 AREG
amphiregulin
chr3_-_197024879 2.009 DLG1
discs, large homolog 1 (Drosophila)
chr2_-_9143742 1.983 NM_138799
 MBOAT2
membrane bound O-acyltransferase domain containing 2
chrX_-_46618596 1.880 SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr2_-_208031570 1.846 KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_+_30454396 1.817 NM_030915
 LBH
limb bud and heart development homolog (mouse)
chr16_+_31483066 1.706 NM_001042454
NM_001164719
 TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr7_-_100860865 1.684 PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr22_+_31477231 1.670 NM_006932
NM_134269
NM_134270
 SMTN


smoothelin


chr6_-_30654406 1.664 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr6_-_30654978 1.653 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr22_+_30792929 1.645 NM_001204204
NM_012429
NM_033382
 SEC14L2


SEC14-like 2 (S. cerevisiae)



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 117 entries
enrichment   p-value GO term description
2.49 2.85e-02 GO:0048145 regulation of fibroblast proliferation
2.01 2.37e-05 GO:0034330 cell junction organization
1.96 2.59e-03 GO:0007265 Ras protein signal transduction
1.94 9.69e-04 GO:0034329 cell junction assembly
1.87 2.08e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.71 2.26e-06 GO:0007411 axon guidance
1.69 1.24e-02 GO:0048732 gland development
1.67 5.14e-08 GO:0048812 neuron projection morphogenesis
1.66 1.11e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.65 1.33e-08 GO:0000904 cell morphogenesis involved in differentiation
1.64 4.27e-08 GO:0031175 neuron projection development
1.64 1.06e-06 GO:0007409 axonogenesis
1.63 6.49e-04 GO:0030029 actin filament-based process
1.61 9.00e-03 GO:0030036 actin cytoskeleton organization
1.61 2.69e-02 GO:0051129 negative regulation of cellular component organization
1.58 6.22e-08 GO:0048666 neuron development
1.58 6.50e-03 GO:0071900 regulation of protein serine/threonine kinase activity
1.56 2.94e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.55 1.03e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.54 6.80e-04 GO:0007264 small GTPase mediated signal transduction

Gene overrepresentation in compartment category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
2.82 4.92e-03 GO:0001725 stress fiber
2.63 1.75e-02 GO:0032432 actin filament bundle
2.53 2.06e-02 GO:0042641 actomyosin
1.88 6.32e-03 GO:0005924 cell-substrate adherens junction
1.88 1.00e-02 GO:0005925 focal adhesion
1.84 1.10e-03 GO:0005938 cell cortex
1.81 6.14e-04 GO:0005912 adherens junction
1.81 1.87e-02 GO:0030055 cell-substrate junction
1.77 4.74e-04 GO:0070161 anchoring junction
1.77 5.70e-03 GO:0043235 receptor complex
1.63 1.06e-02 GO:0031252 cell leading edge
1.58 4.70e-04 GO:0015629 actin cytoskeleton
1.58 4.76e-02 GO:0030424 axon
1.49 4.71e-04 GO:0043005 neuron projection
1.44 3.17e-05 GO:0030054 cell junction
1.33 1.65e-03 GO:0031410 cytoplasmic vesicle
1.32 1.61e-03 GO:0031982 vesicle
1.32 4.33e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.31 7.02e-03 GO:0031988 membrane-bounded vesicle
1.30 2.88e-03 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.09 4.85e-02 GO:0035591 signaling adaptor activity
1.57 5.93e-08 GO:0008092 cytoskeletal protein binding
1.55 7.01e-04 GO:0003779 actin binding
1.49 4.45e-02 GO:0032403 protein complex binding
1.43 3.29e-06 GO:0019899 enzyme binding
1.37 4.05e-03 GO:0004672 protein kinase activity
1.35 1.39e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.34 1.23e-03 GO:0016301 kinase activity
1.27 2.37e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.25 3.20e-02 GO:0005102 receptor binding
1.20 1.14e-24 GO:0005515 protein binding
1.18 3.21e-02 GO:0032553 ribonucleotide binding
1.18 3.21e-02 GO:0032555 purine ribonucleotide binding
1.17 5.68e-03 GO:0000166 nucleotide binding
1.17 4.46e-02 GO:0017076 purine nucleotide binding
1.07 6.58e-10 GO:0005488 binding