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Motif ID: SREBF1,2.p2

Z-value: 1.255

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_-_10764449	14.923		LOC147727	uncharacterized LOC147727
chr9_-_138391696	11.299	NM_001048265 NM_144654	C9orf116	chromosome 9 open reading frame 116
chr22_-_41593466	9.033
chr1_-_42921676	6.650		ZMYND12	zinc finger, MYND-type containing 12
chr1_-_207119707	6.232	NM_002644	PIGR	polymeric immunoglobulin receptor
chr1_+_183605207	6.203	NM_015149	RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr20_-_39317875	5.825	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr7_+_23286386	5.026		GPNMB	glycoprotein (transmembrane) nmb
chr7_+_23286384	4.752		GPNMB	glycoprotein (transmembrane) nmb
chr12_+_50355278	4.677	NM_001651	AQP5	aquaporin 5
chr7_+_23286390	4.581		GPNMB	glycoprotein (transmembrane) nmb
chr7_+_106685007	4.453	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr19_+_14544100	4.417	NM_002741	PKN1	protein kinase N1
chr4_-_16085309	4.259		PROM1	prominin 1
chr15_-_50978921	4.073		TRPM7	transient receptor potential cation channel, subfamily M, member 7
chrX_+_55744049	3.919	NM_006064 NM_016656	RRAGB	Ras-related GTP binding B
chr22_+_35777087	3.854		HMOX1	heme oxygenase (decycling) 1
chr17_+_17876126	3.835	NM_001130090 NM_001130091 NM_001130092 NM_031294	LRRC48	leucine rich repeat containing 48
chr1_-_109656478	3.821	NM_001122961	C1orf194	chromosome 1 open reading frame 194
chr12_-_63328663	3.820	NM_020700	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_+_105953531	3.803		CRIP1	cysteine-rich protein 1 (intestinal)
chr5_-_121413906	3.783		LOX	lysyl oxidase
chr5_-_121413967	3.696		LOX	lysyl oxidase
chr5_-_121414011	3.656	NM_002317	LOX	lysyl oxidase
chr2_-_238499317	3.588		RAB17	RAB17, member RAS oncogene family
chr15_+_44084039	3.476	NM_001018108 NM_001199875 NM_001199876	SERF2	small EDRK-rich factor 2
chr8_-_110657025	3.469	NM_001099753 NM_001099754 NM_001099755	SYBU	syntabulin (syntaxin-interacting)
chr12_-_65153182	3.446		GNS	glucosamine (N-acetyl)-6-sulfatase
chr17_+_78075299	3.391	NM_000152 NM_001079803 NM_001079804	GAA	glucosidase, alpha; acid
chr8_-_71581354	3.369		LACTB2	lactamase, beta 2
chr11_+_65479685	3.283		KAT5	K(lysine) acetyltransferase 5
chr10_+_69644341	3.248	NM_012238	SIRT1	sirtuin 1
chr8_+_75896707	3.227	NM_031461	CRISPLD1	cysteine-rich secretory protein LCCL domain containing 1
chr14_+_45431333	3.200	NM_015091	FAM179B	family with sequence similarity 179, member B
chr16_+_84178864	3.193	NM_178452	DNAAF1	dynein, axonemal, assembly factor 1
chr15_-_50978726	3.132		TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr1_+_20512577	3.076	NM_152376	UBXN10	UBX domain protein 10
chr16_-_88923233	3.028		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr12_-_65153148	2.996		GNS	glucosamine (N-acetyl)-6-sulfatase
chr1_-_42921923	2.980	NM_001146192 NM_032257	ZMYND12	zinc finger, MYND-type containing 12
chr12_-_65153055	2.951		GNS	glucosamine (N-acetyl)-6-sulfatase
chr17_+_79935493	2.937		ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_154928564	2.900	NM_020524	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr19_+_14544216	2.876		PKN1	protein kinase N1
chr6_-_90121656	2.838		RRAGD	Ras-related GTP binding D
chr11_+_126081618	2.819	NM_024556	FAM118B	family with sequence similarity 118, member B
chr12_+_112451261	2.809		ERP29	endoplasmic reticulum protein 29
chr7_+_150065859	2.778	NM_001099695 NM_001099696 NM_013400	REPIN1	replication initiator 1
chr17_+_72270385	2.771	NM_001172810 NM_023036	DNAI2	dynein, axonemal, intermediate chain 2
chr3_-_122512526	2.768	NM_024610	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr17_+_78075390	2.767		GAA	glucosidase, alpha; acid
chr6_-_90121966	2.743	NM_021244	RRAGD	Ras-related GTP binding D
chr10_-_25304865	2.726	NM_145010	ENKUR	enkurin, TRPC channel interacting protein
chr11_+_65479472	2.705	NM_001206833 NM_006388 NM_182709 NM_182710	KAT5	K(lysine) acetyltransferase 5
chr10_+_69644708	2.687		SIRT1	sirtuin 1
chr19_-_11545900	2.687	NM_145045	CCDC151	coiled-coil domain containing 151
chr15_+_45315301	2.654	NM_003104	SORD	sorbitol dehydrogenase
chr8_-_71581419	2.625	NM_016027	LACTB2	lactamase, beta 2
chr12_-_112450914	2.577	NM_001193453 NM_001193531 NM_138341	LOC728543 TMEM116	uncharacterized LOC728543 transmembrane protein 116
chr20_-_2821245	2.558	NM_022760	FAM113A	family with sequence similarity 113, member A
chr3_-_45883562	2.548	NM_020347	LZTFL1	leucine zipper transcription factor-like 1
chr5_+_43603312	2.540		NNT	nicotinamide nucleotide transhydrogenase
chr6_-_90121911	2.483		RRAGD	Ras-related GTP binding D
chr19_-_36545298	2.471		THAP8	THAP domain containing 8
chr5_+_140220811	2.466	NM_018911 NM_031856	PCDHA8	protocadherin alpha 8
chr5_+_172483285	2.451	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr19_+_45504686	2.449	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr12_+_112451151	2.445	NM_001034025 NM_006817	ERP29	endoplasmic reticulum protein 29
chr22_+_35777051	2.431	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr22_-_39268230	2.420	NM_014292	CBX6	chromobox homolog 6
chr14_+_77564570	2.417	NM_033426	KIAA1737	KIAA1737
chr17_+_1628032	2.415	NM_001163809	WDR81	WD repeat domain 81
chrX_+_152240726	2.408	NM_001170944 NM_001242319 NM_032882	PNMA6C PNMA6D PNMA6A	paraneoplastic antigen like 6C paraneoplastic antigen like 6D paraneoplastic antigen like 6A
chr7_+_116593554	2.405		ST7	suppression of tumorigenicity 7
chr7_+_23286277	2.390	NM_001005340 NM_002510	GPNMB	glycoprotein (transmembrane) nmb
chr7_+_23286420	2.381		GPNMB	glycoprotein (transmembrane) nmb
chr7_+_150065968	2.377		REPIN1	replication initiator 1
chr9_+_135754284	2.370	NM_018956	C9orf9	chromosome 9 open reading frame 9
chr4_-_149363498	2.315	NM_000901 NM_001166104	NR3C2	nuclear receptor subfamily 3, group C, member 2
chr11_+_67159421	2.310	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr1_-_154531083	2.285	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr14_+_74486049	2.251	NM_025057	C14orf45	chromosome 14 open reading frame 45
chr12_+_104458235	2.226	NM_013320	HCFC2	host cell factor C2
chr12_-_65153189	2.225	NM_002076	GNS	glucosamine (N-acetyl)-6-sulfatase
chr11_-_6640645	2.220		TPP1	tripeptidyl peptidase I
chr9_-_90589593	2.135	NM_001039803 NM_001170639 NM_001170640 NM_012119 NM_178432	CDK20	cyclin-dependent kinase 20
chr9_-_140009171	2.127		DPP7	dipeptidyl-peptidase 7
chr9_-_140009169	2.120		DPP7	dipeptidyl-peptidase 7
chr12_-_63328857	2.119		PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr7_+_29603499	2.118		PRR15	proline rich 15
chr14_-_94849552	2.112		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr8_+_17780351	2.093	NM_006197	PCM1	pericentriolar material 1
chr9_-_140009194	2.065	NM_013379	DPP7	dipeptidyl-peptidase 7
chr9_-_140009162	2.060		DPP7	dipeptidyl-peptidase 7
chr9_-_90589360	2.057		CDK20	cyclin-dependent kinase 20
chrX_+_101975641	2.028	NM_001142524 NM_001142525 NM_001142526 NM_001142527 NM_001142528 NM_030639	BHLHB9	basic helix-loop-helix domain containing, class B, 9
chr2_+_46926049	2.028	NM_014011	SOCS5	suppressor of cytokine signaling 5
chrX_-_34675366	2.024	NM_031442	TMEM47	transmembrane protein 47
chr20_-_2821120	1.983		FAM113A	family with sequence similarity 113, member A
chr12_+_133614138	1.947		ZNF84	zinc finger protein 84
chr4_+_106067031	1.944	NM_017628	TET2	tet methylcytosine dioxygenase 2
chr17_-_35969401	1.939	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chr9_-_131709783	1.928	NM_014908	DOLK	dolichol kinase
chr12_+_133614052	1.925		ZNF84	zinc finger protein 84
chr6_+_87865261	1.915	NM_015021	ZNF292	zinc finger protein 292
chr1_-_204329043	1.913	NM_014935	PLEKHA6	pleckstrin homology domain containing, family A member 6
chr17_-_30186217	1.912	NM_018405	C17orf79	chromosome 17 open reading frame 79
chr17_+_3540004	1.909		CTNS	cystinosin, lysosomal cystine transporter
chr19_-_291168	1.899	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr5_-_139944045	1.884	NM_006051 NM_133172 NM_133173 NM_133174	APBB3	amyloid beta (A4) precursor protein-binding, family B, member 3
chr9_+_135753711	1.882		C9orf9	chromosome 9 open reading frame 9
chr5_+_89854610	1.879	NM_032119	GPR98	G protein-coupled receptor 98
chr17_-_7197896	1.861		YBX2	Y box binding protein 2
chr19_+_5681139	1.857		HSD11B1L	hydroxysteroid (11-beta) dehydrogenase 1-like
chr4_-_23891608	1.850	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr5_+_43603216	1.847	NM_182977	NNT	nicotinamide nucleotide transhydrogenase
chr15_+_44084517	1.834	NM_001199878	SERF2-C15ORF63 SERF2	SERF2-C15orf63 readthrough small EDRK-rich factor 2
chr16_-_4897265	1.828	NM_032569	GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr7_+_23286401	1.816		GPNMB	glycoprotein (transmembrane) nmb
chr3_-_187463227	1.815		BCL6	B-cell CLL/lymphoma 6
chr19_+_5681016	1.795	NM_198704 NM_198705 NM_198533 NM_198707 NM_198706 NM_198708	HSD11B1L	hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_-_36545119	1.795		THAP8	THAP domain containing 8
chr4_+_39184023	1.794	NM_025132	WDR19	WD repeat domain 19
chr22_+_31003069	1.784	NM_000355 NM_001184726	TCN2	transcobalamin II
chr5_-_122759003	1.745	NM_001166226 NM_153223	CEP120	centrosomal protein 120kDa
chr11_+_18343794	1.736	NM_001142307 NM_005316	GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr11_+_1330977	1.733		LOC255512	uncharacterized LOC255512
chr1_-_27339326	1.706	NM_052943	FAM46B	family with sequence similarity 46, member B
chr1_-_154928595	1.705		PBXIP1	pre-B-cell leukemia homeobox interacting protein 1
chr1_-_217250230	1.701	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr17_-_7197866	1.694	NM_015982	YBX2	Y box binding protein 2
chr3_-_11610264	1.683	NM_001128221	VGLL4	vestigial like 4 (Drosophila)
chr17_-_7197811	1.673		YBX2	Y box binding protein 2
chr6_-_33386064	1.667	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr2_+_85980600	1.665	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr9_+_6757919	1.661		KDM4C	lysine (K)-specific demethylase 4C
chr9_+_6757636	1.659	NM_001146694 NM_001146695 NM_015061	KDM4C	lysine (K)-specific demethylase 4C
chr20_+_44520021	1.656		CTSA	cathepsin A
chr3_-_187463474	1.649	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr15_-_50978960	1.637		TRPM7	transient receptor potential cation channel, subfamily M, member 7
chr14_-_88459459	1.633		GALC	galactosylceramidase
chr20_+_44520203	1.628		CTSA	cathepsin A
chr7_+_102074002	1.627		ORAI2	ORAI calcium release-activated calcium modulator 2
chr11_-_6640578	1.620		TPP1	tripeptidyl peptidase I
chr10_-_32217687	1.610		ARHGAP12	Rho GTPase activating protein 12
chr1_+_61869699	1.600		NFIA	nuclear factor I/A
chr1_+_151483861	1.598	NM_020770	CGN	cingulin
chr17_+_42977141	1.593	NM_213607	CCDC103	coiled-coil domain containing 103
chr17_-_62502410	1.593	NM_004396	DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr4_+_980775	1.589	NM_000203	IDUA	iduronidase, alpha-L-
chr1_-_27339448	1.586		FAM46B	family with sequence similarity 46, member B
chr4_+_37455551	1.585	NM_001104629	C4orf19	chromosome 4 open reading frame 19
chr15_+_44084493	1.570		SERF2	small EDRK-rich factor 2
chr17_-_40346427	1.562	NM_001142622 NM_001142623 NM_032484	GHDC	GH3 domain containing
chr10_-_32217762	1.552	NM_018287	ARHGAP12	Rho GTPase activating protein 12
chr5_+_149340437	1.545		SLC26A2	solute carrier family 26 (sulfate transporter), member 2
chrY_+_15016698	1.544	NM_004660	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr17_+_1627833	1.535	NM_001163811	WDR81	WD repeat domain 81
chr11_-_6640644	1.533		TPP1	tripeptidyl peptidase I
chr12_+_72233486	1.532	NM_001146213 NM_001146214 NM_022771	TBC1D15	TBC1 domain family, member 15
chr18_+_9136742	1.531	NM_001083625 NM_015208	ANKRD12	ankyrin repeat domain 12
chr12_+_66582914	1.519	NM_001142523 NM_007199	IRAK3	interleukin-1 receptor-associated kinase 3
chr19_-_5340700	1.516	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr3_+_51428698	1.498	NM_013286	RBM15B	RNA binding motif protein 15B
chr12_-_110841409	1.498		ANAPC7	anaphase promoting complex subunit 7
chr3_+_113465910	1.472		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr19_+_50016500	1.472		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr4_+_15480833	1.470		CC2D2A	coiled-coil and C2 domain containing 2A
chr4_-_657424	1.468
chr17_-_42200957	1.467		HDAC5	histone deacetylase 5
chr12_+_113623364	1.466	NM_032848	C12orf52	chromosome 12 open reading frame 52
chr17_+_48172508	1.465	NM_001199900 NM_002611 NM_001199899	PDK2	pyruvate dehydrogenase kinase, isozyme 2
chr19_+_7587436	1.464	NM_020533	MCOLN1	mucolipin 1
chr16_+_699277	1.430	NM_145294	WDR90	WD repeat domain 90
chrX_-_102565805	1.429	NM_001168399 NM_001168400 NM_001168401 NM_032621	BEX2	brain expressed X-linked 2
chr20_+_44519924	1.424		CTSA	cathepsin A
chr19_+_50016490	1.416		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chrY_+_21729214	1.413		TXLNG2P	taxilin gamma 2, pseudogene
chr9_+_36136710	1.410	NM_022343	GLIPR2	GLI pathogenesis-related 2
chr18_-_29523087	1.405	NM_014939	TRAPPC8	trafficking protein particle complex 8
chr1_+_17248425	1.403	NM_014675	CROCC	ciliary rootlet coiled-coil, rootletin
chr8_+_17780492	1.403		PCM1	pericentriolar material 1
chr12_+_90103470	1.400		LOC338758	uncharacterized LOC338758
chr20_+_37590969	1.396	NM_001190809 NM_021931	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr17_-_42201009	1.390	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr19_-_55972935	1.386		ISOC2	isochorismatase domain containing 2
chr1_+_226016428	1.382		EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)
chr7_-_30029284	1.381	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr15_-_72668301	1.377	NM_000520	HEXA	hexosaminidase A (alpha polypeptide)
chr19_-_291335	1.376	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr12_+_122356446	1.367	NM_001178003 NM_144668	WDR66	WD repeat domain 66
chr11_-_8892909	1.362		ST5	suppression of tumorigenicity 5
chr11_-_106888829	1.362	NM_000855	GUCY1A2	guanylate cyclase 1, soluble, alpha 2
chr14_+_96858436	1.359	NM_152327	AK7	adenylate kinase 7
chr17_+_40440481	1.356		STAT5A	signal transducer and activator of transcription 5A
chrX_-_101397370	1.343	NM_001006938	TCEAL6	transcription elongation factor A (SII)-like 6
chr20_+_44519965	1.342		CTSA	cathepsin A
chr13_-_50159628	1.331		RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr19_+_4343523	1.307	NM_001159846 NM_032868	MPND	MPN domain containing
chr7_-_36429695	1.306	NM_001100425	KIAA0895	KIAA0895

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.38	6.19e-05	GO:0015682	ferric iron transport
6.38	6.19e-05	GO:0033572	transferrin transport
1.22	2.45e-04	GO:0044237	cellular metabolic process
4.17	7.46e-04	GO:0006818	hydrogen transport
1.18	3.58e-03	GO:0008152	metabolic process
4.30	5.59e-03	GO:0007033	vacuole organization
1.25	6.74e-03	GO:0044260	cellular macromolecule metabolic process
3.06	8.69e-03	GO:0000041	transition metal ion transport
3.88	1.02e-02	GO:0006826	iron ion transport
3.81	1.29e-02	GO:0015992	proton transport
3.47	2.37e-02	GO:0055072	iron ion homeostasis
1.17	4.00e-02	GO:0044238	primary metabolic process
4.91	4.25e-02	GO:0015988	energy coupled proton transport, against electrochemical gradient
4.91	4.25e-02	GO:0015991	ATP hydrolysis coupled proton transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.25	2.21e-15	GO:0043227	membrane-bounded organelle
1.25	2.73e-15	GO:0043231	intracellular membrane-bounded organelle
1.16	4.13e-12	GO:0005622	intracellular
1.20	5.95e-12	GO:0043226	organelle
1.16	6.01e-12	GO:0044424	intracellular part
1.20	9.43e-12	GO:0043229	intracellular organelle
2.92	1.12e-11	GO:0005773	vacuole
1.29	1.36e-08	GO:0044446	intracellular organelle part
1.28	5.77e-08	GO:0044422	organelle part
2.71	9.57e-08	GO:0000323	lytic vacuole
2.71	9.57e-08	GO:0005764	lysosome
1.49	2.05e-07	GO:0031974	membrane-enclosed lumen
1.49	2.24e-07	GO:0043233	organelle lumen
1.49	5.11e-07	GO:0070013	intracellular organelle lumen
3.02	6.42e-06	GO:0044437	vacuolar part
1.17	1.26e-05	GO:0005737	cytoplasm
1.24	2.22e-05	GO:0005634	nucleus
2.97	2.78e-05	GO:0005774	vacuolar membrane
1.22	3.30e-05	GO:0044444	cytoplasmic part
1.57	5.35e-05	GO:0005654	nucleoplasm
1.45	1.91e-04	GO:0031981	nuclear lumen
1.39	5.08e-04	GO:0044428	nuclear part
6.63	1.04e-03	GO:0033176	proton-transporting V-type ATPase complex
1.85	3.99e-03	GO:0005768	endosome
2.77	4.81e-03	GO:0005770	late endosome
1.63	8.69e-03	GO:0044451	nucleoplasm part
2.71	1.04e-02	GO:0005765	lysosomal membrane
1.32	2.22e-02	GO:0031090	organelle membrane
1.05	3.07e-02	GO:0044464	cell part
1.05	3.14e-02	GO:0005623	cell
3.77	4.28e-02	GO:0016469	proton-transporting two-sector ATPase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.08	2.29e-02	GO:0005488	binding
1.14	4.66e-02	GO:0005515	protein binding
1.82	4.66e-02	GO:0003712	transcription cofactor activity
1.82	4.97e-02	GO:0000988	protein binding transcription factor activity
1.82	4.97e-02	GO:0000989	transcription factor binding transcription factor activity