Motif ID: STAT2,4,6.p2

Z-value: 1.523


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT2chr12_-_567539160.383.7e-02Click!
STAT6chr12_-_575040880.319.5e-02Click!
STAT4chr2_-_192015733-0.241.9e-01Click!


Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_89562103 3.490 NM_002048
GAS1
growth arrest-specific 1
chr3_-_187463227 2.391 BCL6
B-cell CLL/lymphoma 6
chr14_+_95078713 2.044 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr19_-_44860798 1.940 NM_001083335
NM_013380
ZFP112

zinc finger protein 112 homolog (mouse)

chr12_-_7245048 1.929 C1R
complement component 1, r subcomponent
chr12_-_7245006 1.927 NM_001733
C1R
complement component 1, r subcomponent
chr5_-_149792370 1.849 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr6_+_32821924 1.849 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr19_-_49567123 1.743 NM_006179
NTF4
neurotrophin 4
chr3_-_148939784 1.680 NM_000096
CP
ceruloplasmin (ferroxidase)
chr13_-_36705432 1.594 DCLK1
doublecortin-like kinase 1
chr3_-_187463474 1.580 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr12_+_93964801 1.518 SOCS2
suppressor of cytokine signaling 2
chr17_-_80291639 1.491 SECTM1
secreted and transmembrane 1
chr8_-_10512616 1.483 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr6_-_28304151 1.454 NM_001243241
NM_001243242
NM_001243244
NM_030899
ZNF323



zinc finger protein 323



chr11_+_76745434 1.451 NM_138706
B3GNT6
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase)
chr17_-_80291610 1.446 SECTM1
secreted and transmembrane 1
chr17_+_38171613 1.422 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr10_+_115511212 1.409 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.75 1.22e-03 GO:0045087 innate immune response
1.45 2.22e-02 GO:0006955 immune response

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.14 1.46e-03 GO:0005634 nucleus
1.11 4.26e-05 GO:0043231 intracellular membrane-bounded organelle
1.11 5.70e-05 GO:0043227 membrane-bounded organelle
1.08 6.46e-03 GO:0043229 intracellular organelle
1.08 6.58e-03 GO:0043226 organelle
1.06 3.20e-02 GO:0044424 intracellular part
1.06 3.63e-02 GO:0005622 intracellular

Nothing significant found in function category.