Motif ID: TBP.p2

Z-value: 2.795


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_1708634200.202.8e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153029987 27.813 NM_005988
SPRR2A
small proline-rich protein 2A
chr1_-_153044083 20.328 NM_001017418
SPRR2B
small proline-rich protein 2B
chr8_-_23261626 18.662 LOXL2
lysyl oxidase-like 2
chr8_-_23261591 16.446 LOXL2
lysyl oxidase-like 2
chr1_-_153067000 15.857 NM_001024209
SPRR2E
small proline-rich protein 2E
chr8_-_23261632 15.446 LOXL2
lysyl oxidase-like 2
chr1_-_153013593 15.351 NM_006945
SPRR2D
small proline-rich protein 2D
chr2_-_216300770 12.988 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr4_+_75310852 10.593 NM_001657
AREG
amphiregulin
chr7_+_100770378 10.547 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr21_-_28217692 10.442 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_-_2903461 10.369 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr15_+_45722762 9.999 NM_032413
NM_197955
C15orf48

chromosome 15 open reading frame 48

chr12_+_8975149 9.540 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr1_+_152881022 9.425 NM_005547
IVL
involucrin
chr8_-_23261675 9.070 NM_002318
LOXL2
lysyl oxidase-like 2
chr21_-_28217272 8.713 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_+_10381763 8.472 ICAM1
intercellular adhesion molecule 1
chr17_-_38859976 8.357 NM_019016
KRT24
keratin 24
chr22_+_31480981 8.342 NM_001207018
SMTN
smoothelin
chr1_+_17575592 8.266 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr10_+_17271276 8.064 VIM
vimentin
chr15_+_81071708 7.919 NM_018689
KIAA1199
KIAA1199
chr19_+_6531009 7.770 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr8_+_86376130 7.695 NM_000067
CA2
carbonic anhydrase II
chr1_-_152386727 7.401 NM_016190
CRNN
cornulin
chr12_-_52845862 7.374 NM_005555
KRT6B
keratin 6B
chr19_+_18496966 7.299 NM_004864
GDF15
growth differentiation factor 15
chr8_-_6735438 7.297 NM_005218
DEFB1
defensin, beta 1
chr17_-_39553796 7.146 NM_002277
KRT31
keratin 31
chr14_+_75745480 7.023 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr10_+_17271277 6.978 VIM
vimentin
chr1_+_37940180 6.253 ZC3H12A
zinc finger CCCH-type containing 12A
chr6_-_27114577 5.898 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr11_+_43963809 5.616 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr15_-_63674074 5.225 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr17_-_39507055 5.176 NM_004138
KRT33A
keratin 33A
chr2_+_228678556 5.170 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr15_-_63673918 5.166 CA12
carbonic anhydrase XII
chr7_+_143013218 5.039 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr18_+_21718930 4.836 NM_012189
NM_138643
NM_153768
NM_153769
NM_153770
CABYR




calcium binding tyrosine-(Y)-phosphorylation regulated




chr1_+_153003677 4.764 NM_003125
SPRR1B
small proline-rich protein 1B
chr18_+_21719025 4.704 CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr10_-_3827418 4.627 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr5_-_16742336 4.506 MYO10
myosin X
chr16_+_58534045 4.489 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr15_-_75017710 4.456 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_+_676346 4.287 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr19_+_7049349 4.286 NM_144614
MBD3L2
methyl-CpG binding domain protein 3-like 2
chr19_+_8117645 4.215 NM_001201359
NM_005624
CCL25

chemokine (C-C motif) ligand 25

chr6_-_26124130 4.203 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr7_-_41742666 4.199 NM_002192
INHBA
inhibin, beta A
chr10_+_17271302 4.187 VIM
vimentin
chr10_+_54074037 4.097 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr15_+_39873276 4.048 NM_003246
THBS1
thrombospondin 1
chr11_-_102826433 4.025 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr11_-_64646053 4.006 NM_006795
EHD1
EH-domain containing 1
chr16_+_71392637 3.919 CALB2
calbindin 2
chr7_+_107301079 3.919 NM_000441
SLC26A4
solute carrier family 26, member 4
chr19_-_7040183 3.909 NM_001164419
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr16_+_71392615 3.900 NM_001740
NM_007088
CALB2

calbindin 2

chr19_-_51487070 3.805 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr8_-_23021447 3.803 NM_003840
TNFRSF10D
tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr12_+_13044352 3.761 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr15_+_45406518 3.720 NM_207581
DUOXA2
dual oxidase maturation factor 2
chrX_-_106960268 3.709 NM_004089
TSC22D3
TSC22 domain family, member 3
chr14_-_53417808 3.686 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr1_-_204135420 3.670 NM_000537
REN
renin
chr11_+_18287807 3.648 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr19_+_7030593 3.616 NM_001136507
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr7_+_74188308 3.496 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr1_-_8086347 3.437 ERRFI1
ERBB receptor feedback inhibitor 1
chr11_-_18270167 3.427 NM_001199744
NM_001127380
NM_030754
SAA2-SAA4
SAA2

SAA2-SAA4 readthrough
serum amyloid A2

chr12_-_52779362 3.356 NM_033045
KRT84
keratin 84
chr1_-_153363544 3.349 NM_002964
S100A8
S100 calcium binding protein A8
chr11_+_62186506 3.333 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr19_-_7058644 3.309 NM_001164425
MBD3L3
methyl-CpG binding domain protein 3-like 3
chr16_+_56598960 3.295 NM_032935
MT4
metallothionein 4
chr8_+_22960326 3.287 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chrX_-_106960028 3.277 TSC22D3
TSC22 domain family, member 3
chr12_-_53074172 3.264 NM_006121
KRT1
keratin 1
chr1_-_156675237 3.258 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr17_-_39780762 3.189 NM_000422
KRT17
keratin 17
chr11_-_2906960 3.182 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr6_+_26124372 3.175 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr10_+_17271341 3.120 VIM
vimentin
chr4_-_156787377 3.074 NM_017419
ACCN5
amiloride-sensitive cation channel 5, intestinal
chr9_+_33240165 3.027 NM_014471
SPINK4
serine peptidase inhibitor, Kazal type 4
chr6_+_12290528 3.007 NM_001168319
NM_001955
EDN1

endothelin 1

chr10_-_3827205 2.987 KLF6
Kruppel-like factor 6
chr6_-_26216871 2.937 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr16_-_21222867 2.920 NM_003460
ZP2
zona pellucida glycoprotein 2 (sperm receptor)
chr10_+_94833646 2.889 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr9_+_139557378 2.874 NM_016215
EGFL7
EGF-like-domain, multiple 7
chr19_-_2051222 2.866 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr1_+_37940129 2.822 ZC3H12A
zinc finger CCCH-type containing 12A
chr15_+_62359175 2.815 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr6_-_27775683 2.785 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr11_-_102651321 2.779 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr2_+_7017795 2.738 NM_080657
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_+_16085245 2.729 NM_017556
FBLIM1
filamin binding LIM protein 1
chr1_-_149783910 2.673 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr3_-_81810914 2.672 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr4_+_100871625 2.665 LOC256880
uncharacterized LOC256880
chr8_-_143695812 2.656 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr2_-_241080072 2.646 NM_148961
OTOS
otospiralin
chr16_-_11370305 2.631 NM_002762
PRM2
protamine 2
chr10_-_74856590 2.627 P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr11_+_61008643 2.602 NM_014224
PGA5
pepsinogen 5, group I (pepsinogen A)
chr6_-_26043884 2.584 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr20_-_44540685 2.581 PLTP
phospholipid transfer protein
chr2_-_43453146 2.546 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr12_-_53012332 2.539 NM_175068
KRT73
keratin 73
chr11_+_66188474 2.475 NM_178864
NPAS4
neuronal PAS domain protein 4
chr17_-_39538635 2.463 NM_021013
KRT34
keratin 34
chr17_-_39768939 2.460 NM_005557
KRT16
keratin 16
chr3_+_101546833 2.451 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr2_-_43453737 2.412 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr3_-_81810618 2.386 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr20_+_42086533 2.386 SRSF6
serine/arginine-rich splicing factor 6
chr6_+_64282449 2.385 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_-_39222126 2.321 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr8_+_70378858 2.306 NM_001128204
NM_015170
SULF1

sulfatase 1

chr1_+_153330329 2.305 NM_002965
S100A9
S100 calcium binding protein A9
chr1_-_27481400 2.290 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr17_+_34538464 2.278 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr17_-_10276321 2.277 NM_003802
MYH13
myosin, heavy chain 13, skeletal muscle
chr21_-_31859666 2.257 NM_181608
KRTAP19-2
keratin associated protein 19-2
chr14_+_94492747 2.202 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr12_-_53189780 2.199 NM_057088
KRT3
keratin 3
chr7_+_134464161 2.174 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr7_-_134143804 2.171 AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr11_+_62432778 2.149 NM_001043229
METTL12
methyltransferase like 12
chr6_+_32006092 2.118 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr3_-_81810816 2.103 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr16_+_56659584 2.096 NM_175617
MT1E
metallothionein 1E
chr1_+_40420802 2.091 MFSD2A
major facilitator superfamily domain containing 2A
chr2_-_172291227 2.089 NM_024770
METTL8
methyltransferase like 8
chr16_+_56659679 2.087 MT1E
metallothionein 1E
chr11_-_64645925 2.079 EHD1
EH-domain containing 1
chr17_+_34640030 2.078 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chrX_+_153626570 2.077 NM_006013
RPL10
ribosomal protein L10
chr20_+_47895178 2.052 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr5_+_179247841 2.039 NM_003900
SQSTM1
sequestosome 1
chr2_-_43453724 2.028 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr2_-_208994408 2.009 NM_020989
CRYGC
crystallin, gamma C
chr6_-_2842069 1.990 NM_030666
SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_-_26250832 1.958 NM_021018
HIST1H3J
HIST1H3F
histone cluster 1, H3j
histone cluster 1, H3f
chr18_+_29171729 1.951 NM_000371
TTR
transthyretin
chr16_-_4292052 1.936 NM_001098814
SRL
sarcalumenin
chr4_-_74853819 1.912 NM_002704
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr12_-_52715140 1.908 NM_002282
KRT83
keratin 83
chr17_-_61973870 1.902 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chrX_+_70797873 1.884 NM_052957
ACRC
acidic repeat containing
chr1_-_149399159 1.854 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr2_-_27531113 1.840 NM_003353
UCN
urocortin
chr3_-_151047309 1.839 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr16_-_56701904 1.811 NM_005950
MT1G
metallothionein 1G
chr4_+_169013687 1.802 NM_007193
ANXA10
annexin A10
chr6_-_150346599 1.791 NM_130900
RAET1L
retinoic acid early transcript 1L
chr17_-_39211462 1.787 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr9_-_139622599 1.771 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chr17_-_61950997 1.752 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr17_-_48278987 1.747 NM_000088
COL1A1
collagen, type I, alpha 1
chr1_+_202509241 1.746 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr4_+_74606222 1.745 NM_000584
IL8
interleukin 8
chr1_+_37940074 1.745 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr2_+_28718937 1.740 NM_001170585
NM_153021
PLB1

phospholipase B1

chr8_-_131028674 1.733 FAM49B
family with sequence similarity 49, member B
chr4_+_37892698 1.717 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr1_+_192544856 1.708 NM_002922
RGS1
regulator of G-protein signaling 1
chr3_-_99594915 1.705 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr20_+_47895168 1.694 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr6_+_25727004 1.682 NM_170610
HIST1H2BA
histone cluster 1, H2ba
chr1_-_173837122 1.680 GAS5
growth arrest-specific 5 (non-protein coding)
chr6_+_64281910 1.658 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr7_-_134143864 1.621 NM_001628
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr19_+_12902295 1.604 NM_002229
JUNB
jun B proto-oncogene
chr12_-_92539614 1.597 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr5_-_147286064 1.586 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr17_-_39216343 1.575 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr4_+_119199906 1.568 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr18_-_44556448 1.563 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr8_-_48650703 1.549 NM_005195
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr10_-_74856656 1.546 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr2_+_10262853 1.543 NM_001034
RRM2
ribonucleotide reductase M2
chr1_+_159557615 1.529 NM_001639
APCS
amyloid P component, serum
chr19_+_10381516 1.527 NM_000201
ICAM1
intercellular adhesion molecule 1
chr7_-_94285477 1.509 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr6_+_27100784 1.504 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr7_-_94285372 1.503 SGCE
sarcoglycan, epsilon
chr7_-_94285426 1.499 SGCE
sarcoglycan, epsilon
chr12_-_53171104 1.488 NM_015848
KRT76
keratin 76
chr5_-_179780314 1.477 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr16_+_56672577 1.464 NM_005946
MT1A
metallothionein 1A
chr19_-_55918980 1.462 UBE2S
ubiquitin-conjugating enzyme E2S
chr12_+_41086189 1.461 NM_001843
NM_175038
CNTN1

contactin 1

chr6_-_26017960 1.453 NM_005325
HIST1H1A
histone cluster 1, H1a
chr12_+_52627007 1.442 KRT7
keratin 7
chr9_+_137772653 1.428 NM_004108
NM_015837
FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.47 3.73e-15 GO:0006334 nucleosome assembly
8.04 1.70e-14 GO:0031497 chromatin assembly
7.64 6.99e-14 GO:0034728 nucleosome organization
7.35 2.04e-13 GO:0065004 protein-DNA complex assembly
6.59 3.57e-13 GO:0006323 DNA packaging
6.96 9.22e-13 GO:0071824 protein-DNA complex subunit organization
1.90 1.69e-11 GO:0042221 response to chemical stimulus
5.66 2.64e-11 GO:0071103 DNA conformation change
1.98 1.14e-10 GO:0048513 organ development
5.78 1.29e-10 GO:0006333 chromatin assembly or disassembly
1.47 2.12e-10 GO:0032501 multicellular organismal process
2.62 2.81e-10 GO:0006952 defense response
3.80 1.12e-08 GO:0006954 inflammatory response
3.02 1.15e-08 GO:0034621 cellular macromolecular complex subunit organization
2.42 2.47e-08 GO:0009888 tissue development
3.34 3.82e-08 GO:0034622 cellular macromolecular complex assembly
2.40 6.55e-08 GO:0043933 macromolecular complex subunit organization
1.59 1.67e-07 GO:0048856 anatomical structure development
1.70 2.25e-07 GO:0006950 response to stress
2.29 3.80e-07 GO:0051704 multi-organism process
1.50 5.44e-07 GO:0032502 developmental process
1.59 2.52e-06 GO:0048731 system development
2.20 3.36e-06 GO:0009611 response to wounding
2.51 4.33e-06 GO:0009725 response to hormone stimulus
1.49 1.04e-05 GO:0007275 multicellular organismal development
2.82 1.50e-05 GO:0051707 response to other organism
1.93 1.70e-05 GO:0010033 response to organic substance
2.26 2.12e-05 GO:0071844 cellular component assembly at cellular level
2.33 3.13e-05 GO:0009719 response to endogenous stimulus
2.08 3.60e-05 GO:0070887 cellular response to chemical stimulus
2.28 4.70e-05 GO:0065003 macromolecular complex assembly
3.65 5.65e-05 GO:0008544 epidermis development
3.26 8.48e-05 GO:0009617 response to bacterium
4.72 1.40e-04 GO:0008217 regulation of blood pressure
1.85 1.45e-04 GO:0051239 regulation of multicellular organismal process
1.95 1.99e-04 GO:0022607 cellular component assembly
11.55 2.87e-04 GO:0045103 intermediate filament-based process
2.44 2.90e-04 GO:0009607 response to biotic stimulus
2.05 3.36e-04 GO:0040011 locomotion
2.01 3.93e-04 GO:0050793 regulation of developmental process
2.12 4.39e-04 GO:0006955 immune response
3.01 4.46e-04 GO:0010035 response to inorganic substance
1.58 5.38e-04 GO:0065008 regulation of biological quality
1.82 6.89e-04 GO:0002376 immune system process
3.40 7.53e-04 GO:0010817 regulation of hormone levels
2.94 1.15e-03 GO:0048545 response to steroid hormone stimulus
1.82 1.17e-03 GO:0044085 cellular component biogenesis
1.91 1.21e-03 GO:0009605 response to external stimulus
11.89 1.41e-03 GO:0045104 intermediate filament cytoskeleton organization
9.62 1.49e-03 GO:0042743 hydrogen peroxide metabolic process
6.87 2.01e-03 GO:0034614 cellular response to reactive oxygen species
1.26 2.04e-03 GO:0050896 response to stimulus
1.90 2.22e-03 GO:0042127 regulation of cell proliferation
2.40 2.76e-03 GO:0051094 positive regulation of developmental process
5.88 3.07e-03 GO:0002526 acute inflammatory response
8.55 4.10e-03 GO:0044243 multicellular organismal catabolic process
7.22 4.52e-03 GO:0044236 multicellular organismal metabolic process
8.25 5.57e-03 GO:0032963 collagen metabolic process
8.25 5.57e-03 GO:0070301 cellular response to hydrogen peroxide
1.84 5.97e-03 GO:0022414 reproductive process
2.19 6.43e-03 GO:0006928 cellular component movement
2.56 7.05e-03 GO:0051240 positive regulation of multicellular organismal process
1.83 7.08e-03 GO:0000003 reproduction
9.62 7.52e-03 GO:0030574 collagen catabolic process
5.29 9.16e-03 GO:0034599 cellular response to oxidative stress
16.04 9.81e-03 GO:0045109 intermediate filament organization
7.70 9.89e-03 GO:0044259 multicellular organismal macromolecule metabolic process
2.91 1.00e-02 GO:0032101 regulation of response to external stimulus
2.03 1.03e-02 GO:0045595 regulation of cell differentiation
6.50 1.16e-02 GO:0072593 reactive oxygen species metabolic process
3.07 1.21e-02 GO:0003013 circulatory system process
3.07 1.21e-02 GO:0008015 blood circulation
3.43 1.37e-02 GO:0042445 hormone metabolic process
2.50 1.63e-02 GO:0043434 response to peptide hormone stimulus
14.44 1.91e-02 GO:0001542 ovulation from ovarian follicle
2.17 1.96e-02 GO:0006935 chemotaxis
2.17 1.96e-02 GO:0042330 taxis
5.35 2.27e-02 GO:0051591 response to cAMP
4.81 2.39e-02 GO:0007631 feeding behavior
3.03 2.50e-02 GO:0006979 response to oxidative stress
2.19 2.87e-02 GO:0009628 response to abiotic stimulus
2.59 2.92e-02 GO:0040012 regulation of locomotion
3.71 3.65e-02 GO:0007565 female pregnancy
9.62 3.83e-02 GO:0042744 hydrogen peroxide catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.68 5.17e-36 GO:0005576 extracellular region
3.95 1.35e-32 GO:0005615 extracellular space
3.43 3.00e-31 GO:0044421 extracellular region part
7.86 1.19e-26 GO:0005882 intermediate filament
6.81 1.02e-23 GO:0045111 intermediate filament cytoskeleton
12.99 7.80e-22 GO:0000786 nucleosome
8.21 1.12e-15 GO:0032993 protein-DNA complex
8.10 4.69e-13 GO:0045095 keratin filament
2.20 4.65e-09 GO:0044430 cytoskeletal part
1.95 6.08e-09 GO:0005856 cytoskeleton
3.89 1.20e-08 GO:0000785 chromatin
1.64 1.73e-08 GO:0043228 non-membrane-bounded organelle
1.64 1.73e-08 GO:0043232 intracellular non-membrane-bounded organelle
3.32 7.40e-05 GO:0030141 stored secretory granule
3.99 2.00e-04 GO:0043292 contractile fiber
3.98 4.31e-04 GO:0030016 myofibril
2.48 4.92e-04 GO:0031012 extracellular matrix
9.62 8.99e-04 GO:0001533 cornified envelope
3.83 1.46e-03 GO:0044449 contractile fiber part
1.33 4.78e-03 GO:0032991 macromolecular complex
2.11 9.67e-03 GO:0044427 chromosomal part
2.27 2.92e-02 GO:0005578 proteinaceous extracellular matrix
4.81 4.46e-02 GO:0031674 I band
4.81 4.46e-02 GO:0034774 secretory granule lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.75 3.07e-18 GO:0005179 hormone activity
3.21 1.22e-14 GO:0005198 structural molecule activity
2.51 4.73e-13 GO:0005102 receptor binding
4.32 6.18e-09 GO:0005125 cytokine activity
3.85 3.64e-06 GO:0005126 cytokine receptor binding
6.10 4.30e-06 GO:0005200 structural constituent of cytoskeleton
3.69 3.21e-05 GO:0001664 G-protein-coupled receptor binding
6.90 1.03e-04 GO:0008009 chemokine activity
6.23 3.15e-04 GO:0042379 chemokine receptor binding
23.10 2.37e-03 GO:0046870 cadmium ion binding
6.04 4.12e-03 GO:0008307 structural constituent of muscle
5.91 5.03e-03 GO:0043498 cell surface binding
2.30 7.30e-03 GO:0030246 carbohydrate binding
3.64 8.44e-03 GO:0008201 heparin binding
2.91 3.73e-02 GO:0001871 pattern binding
2.91 3.73e-02 GO:0008083 growth factor activity
2.91 3.73e-02 GO:0030247 polysaccharide binding
1.08 4.73e-02 GO:0005488 binding