Motif ID: TBP.p2

Z-value: 2.795


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_1708634200.202.8e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_153029987 27.813 NM_005988
 SPRR2A
small proline-rich protein 2A
chr1_-_153044083 20.328 NM_001017418
 SPRR2B
small proline-rich protein 2B
chr8_-_23261626 18.662 LOXL2
lysyl oxidase-like 2
chr8_-_23261591 16.446 LOXL2
lysyl oxidase-like 2
chr1_-_153067000 15.857 NM_001024209
 SPRR2E
small proline-rich protein 2E
chr8_-_23261632 15.446 LOXL2
lysyl oxidase-like 2
chr1_-_153013593 15.351 NM_006945
 SPRR2D
small proline-rich protein 2D
chr2_-_216300770 12.988 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr4_+_75310852 10.593 NM_001657
 AREG
amphiregulin
chr7_+_100770378 10.547 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr21_-_28217692 10.442 NM_006988
 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr6_-_2903461 10.369 NM_004155
 SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr15_+_45722762 9.999 NM_032413
NM_197955
 C15orf48

chromosome 15 open reading frame 48

chr12_+_8975149 9.540 NM_144670
 A2ML1
alpha-2-macroglobulin-like 1
chr1_+_152881022 9.425 NM_005547
 IVL
involucrin
chr8_-_23261675 9.070 NM_002318
 LOXL2
lysyl oxidase-like 2
chr21_-_28217272 8.713 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr19_+_10381763 8.472 ICAM1
intercellular adhesion molecule 1
chr17_-_38859976 8.357 NM_019016
 KRT24
keratin 24
chr22_+_31480981 8.342 NM_001207018
 SMTN
smoothelin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 84 entries
enrichment   p-value GO term description
16.04 9.81e-03 GO:0045109 intermediate filament organization
14.44 1.91e-02 GO:0001542 ovulation from ovarian follicle
11.89 1.41e-03 GO:0045104 intermediate filament cytoskeleton organization
11.55 2.87e-04 GO:0045103 intermediate filament-based process
9.62 1.49e-03 GO:0042743 hydrogen peroxide metabolic process
9.62 7.52e-03 GO:0030574 collagen catabolic process
9.62 3.83e-02 GO:0042744 hydrogen peroxide catabolic process
8.55 4.10e-03 GO:0044243 multicellular organismal catabolic process
8.47 3.73e-15 GO:0006334 nucleosome assembly
8.25 5.57e-03 GO:0032963 collagen metabolic process
8.25 5.57e-03 GO:0070301 cellular response to hydrogen peroxide
8.04 1.70e-14 GO:0031497 chromatin assembly
7.70 9.89e-03 GO:0044259 multicellular organismal macromolecule metabolic process
7.64 6.99e-14 GO:0034728 nucleosome organization
7.35 2.04e-13 GO:0065004 protein-DNA complex assembly
7.22 4.52e-03 GO:0044236 multicellular organismal metabolic process
6.96 9.22e-13 GO:0071824 protein-DNA complex subunit organization
6.87 2.01e-03 GO:0034614 cellular response to reactive oxygen species
6.59 3.57e-13 GO:0006323 DNA packaging
6.50 1.16e-02 GO:0072593 reactive oxygen species metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
12.99 7.80e-22 GO:0000786 nucleosome
9.62 8.99e-04 GO:0001533 cornified envelope
8.21 1.12e-15 GO:0032993 protein-DNA complex
8.10 4.69e-13 GO:0045095 keratin filament
7.86 1.19e-26 GO:0005882 intermediate filament
6.81 1.02e-23 GO:0045111 intermediate filament cytoskeleton
4.81 4.46e-02 GO:0031674 I band
4.81 4.46e-02 GO:0034774 secretory granule lumen
3.99 2.00e-04 GO:0043292 contractile fiber
3.98 4.31e-04 GO:0030016 myofibril
3.95 1.35e-32 GO:0005615 extracellular space
3.89 1.20e-08 GO:0000785 chromatin
3.83 1.46e-03 GO:0044449 contractile fiber part
3.43 3.00e-31 GO:0044421 extracellular region part
3.32 7.40e-05 GO:0030141 stored secretory granule
2.68 5.17e-36 GO:0005576 extracellular region
2.48 4.92e-04 GO:0031012 extracellular matrix
2.27 2.92e-02 GO:0005578 proteinaceous extracellular matrix
2.20 4.65e-09 GO:0044430 cytoskeletal part
2.11 9.67e-03 GO:0044427 chromosomal part

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
23.10 2.37e-03 GO:0046870 cadmium ion binding
8.75 3.07e-18 GO:0005179 hormone activity
6.90 1.03e-04 GO:0008009 chemokine activity
6.23 3.15e-04 GO:0042379 chemokine receptor binding
6.10 4.30e-06 GO:0005200 structural constituent of cytoskeleton
6.04 4.12e-03 GO:0008307 structural constituent of muscle
5.91 5.03e-03 GO:0043498 cell surface binding
4.32 6.18e-09 GO:0005125 cytokine activity
3.85 3.64e-06 GO:0005126 cytokine receptor binding
3.69 3.21e-05 GO:0001664 G-protein-coupled receptor binding
3.64 8.44e-03 GO:0008201 heparin binding
3.21 1.22e-14 GO:0005198 structural molecule activity
2.91 3.73e-02 GO:0001871 pattern binding
2.91 3.73e-02 GO:0008083 growth factor activity
2.91 3.73e-02 GO:0030247 polysaccharide binding
2.51 4.73e-13 GO:0005102 receptor binding
2.30 7.30e-03 GO:0030246 carbohydrate binding
1.08 4.73e-02 GO:0005488 binding