Motif ID: TFEB.p2

Z-value: 0.920


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41702734,
chr6_-_41703938		0.048.4e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_23286384 4.697 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286386 4.658 GPNMB
glycoprotein (transmembrane) nmb
chr19_-_10764449 4.300 LOC147727
uncharacterized LOC147727
chr7_+_23286390 4.244 GPNMB
glycoprotein (transmembrane) nmb
chr22_+_35777087 3.121 HMOX1
heme oxygenase (decycling) 1
chr1_-_207119707 2.910 NM_002644
 PIGR
polymeric immunoglobulin receptor
chr7_+_23286401 2.317 GPNMB
glycoprotein (transmembrane) nmb
chr9_-_138391696 2.268 NM_001048265
NM_144654
 C9orf116

chromosome 9 open reading frame 116

chr7_+_23286420 2.251 GPNMB
glycoprotein (transmembrane) nmb
chr5_+_172483285 2.011 NM_001168393
NM_001168394
NM_153607
 C5orf41


chromosome 5 open reading frame 41


chr22_-_41593466 1.891


chr1_+_183605207 1.842 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr4_-_149363498 1.831 NM_000901
NM_001166104
 NR3C2

nuclear receptor subfamily 3, group C, member 2

chr19_+_45504686 1.805 NM_006509
 RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr1_+_150255228 1.748 NM_144697
 C1orf51
chromosome 1 open reading frame 51
chr22_+_35777051 1.606 NM_002133
 HMOX1
heme oxygenase (decycling) 1
chr4_+_37455551 1.544 NM_001104629
 C4orf19
chromosome 4 open reading frame 19
chr11_+_120894756 1.507 NM_001130047
NM_152715
 TBCEL

tubulin folding cofactor E-like

chrX_+_152240726 1.445 NM_001170944
NM_001242319
NM_032882
 PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chrX_+_55744049 1.431 NM_006064
NM_016656
 RRAGB

Ras-related GTP binding B


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
7.47 4.27e-02 GO:0032006 regulation of TOR signaling cascade
6.41 1.20e-02 GO:0015682 ferric iron transport
6.41 1.20e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
6.41 1.20e-02 GO:0015991 ATP hydrolysis coupled proton transport
6.41 1.20e-02 GO:0033572 transferrin transport
5.78 3.93e-04 GO:0007033 vacuole organization
4.27 3.55e-02 GO:0006818 hydrogen transport
2.00 1.91e-02 GO:0034613 cellular protein localization
1.99 2.24e-02 GO:0070727 cellular macromolecule localization
1.80 1.51e-02 GO:0046907 intracellular transport
1.77 1.16e-02 GO:0045184 establishment of protein localization
1.77 1.27e-02 GO:0015031 protein transport
1.70 5.99e-03 GO:0008104 protein localization
1.63 8.31e-03 GO:0051641 cellular localization
1.62 4.05e-02 GO:0051649 establishment of localization in cell
1.61 1.13e-02 GO:0033036 macromolecule localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
8.54 5.65e-04 GO:0033176 proton-transporting V-type ATPase complex
4.00 1.19e-02 GO:0031902 late endosome membrane
3.88 4.40e-16 GO:0005773 vacuole
3.87 4.32e-07 GO:0005774 vacuolar membrane
3.70 1.23e-06 GO:0044437 vacuolar part
3.60 3.88e-11 GO:0000323 lytic vacuole
3.60 3.88e-11 GO:0005764 lysosome
3.56 4.54e-04 GO:0005765 lysosomal membrane
3.44 7.02e-05 GO:0005769 early endosome
3.29 2.75e-03 GO:0005770 late endosome
2.59 5.89e-04 GO:0010008 endosome membrane
2.57 6.96e-04 GO:0044440 endosomal part
2.19 3.34e-04 GO:0005768 endosome
1.45 9.49e-03 GO:0031981 nuclear lumen
1.42 5.28e-03 GO:0044428 nuclear part
1.39 1.05e-02 GO:0043233 organelle lumen
1.39 1.43e-02 GO:0070013 intracellular organelle lumen
1.37 2.30e-02 GO:0031974 membrane-enclosed lumen
1.28 7.06e-05 GO:0044446 intracellular organelle part
1.27 9.48e-05 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
5.69 2.44e-02 GO:0019829 cation-transporting ATPase activity
1.18 1.32e-02 GO:0005515 protein binding
1.09 2.77e-02 GO:0005488 binding