Motif ID: TGIF1.p2

Z-value: 0.927


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3449972-0.154.3e-01Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_60325073 2.491


chr1_-_24469571 1.994 NM_021258
 IL22RA1
interleukin 22 receptor, alpha 1
chr4_+_69313166 1.896 NM_014058
 TMPRSS11E
transmembrane protease, serine 11E
chr1_+_17531619 1.805 NM_013358
 PADI1
peptidyl arginine deiminase, type I
chr1_-_152386727 1.753 NM_016190
 CRNN
cornulin
chr17_-_39092714 1.495 KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_53442732 1.477 NM_015319
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr9_+_125133322 1.469 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_113594325 1.339 NM_000576
 IL1B
interleukin 1, beta
chr22_-_37640187 1.303 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_-_175443601 1.300 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_-_41130820 1.273 TREM2
triggering receptor expressed on myeloid cells 2
chr4_-_175443791 1.263 NM_000860
NM_001145816
 HPGD

hydroxyprostaglandin dehydrogenase 15-(NAD)

chr1_+_32043745 1.174 NM_001204415
 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr6_-_41130864 1.122 TREM2
triggering receptor expressed on myeloid cells 2
chr9_+_125133228 1.103 NM_000962
NM_080591
 PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr9_+_34652125 1.101 NM_001142784
 IL11RA
interleukin 11 receptor, alpha
chr3_-_189840225 1.100 NM_001134418
 LEPREL1
leprecan-like 1
chr16_+_69139466 1.088 NM_001199280
 HAS3
hyaluronan synthase 3
chr10_+_102123420 1.076



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.73 1.11e-02 GO:0050878 regulation of body fluid levels
1.33 2.17e-02 GO:0065008 regulation of biological quality
1.32 3.98e-02 GO:0048523 negative regulation of cellular process
1.31 3.35e-05 GO:0023052 signaling
1.31 1.18e-04 GO:0007165 signal transduction
1.31 3.56e-02 GO:0048519 negative regulation of biological process
1.26 6.00e-04 GO:0051716 cellular response to stimulus
1.16 3.69e-02 GO:0050896 response to stimulus
1.14 2.14e-02 GO:0065007 biological regulation
1.09 1.31e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.91 7.29e-03 GO:0045095 keratin filament
2.71 1.51e-03 GO:0030016 myofibril
2.69 9.66e-03 GO:0030017 sarcomere
2.65 1.42e-03 GO:0043292 contractile fiber
2.56 9.74e-03 GO:0044449 contractile fiber part
2.56 1.43e-02 GO:0030055 cell-substrate junction
2.54 2.45e-02 GO:0005924 cell-substrate adherens junction
2.54 3.60e-02 GO:0005925 focal adhesion
2.19 4.71e-02 GO:0005912 adherens junction
2.16 2.68e-02 GO:0005882 intermediate filament
2.06 2.83e-02 GO:0045111 intermediate filament cytoskeleton
1.93 7.38e-03 GO:0015629 actin cytoskeleton
1.48 4.21e-05 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
4.09 2.38e-03 GO:0008307 structural constituent of muscle
1.92 6.56e-03 GO:0003779 actin binding
1.76 1.34e-03 GO:0008092 cytoskeletal protein binding
1.16 2.89e-04 GO:0005515 protein binding