Motif ID: UAAUGCU

Z-value: 0.572


Mature miRNA associated with seed UAAUGCU:

NamemiRBase Accession
hsa-miR-155 MIMAT0000646



Activity profile for motif UAAUGCU.

activity profile for motif UAAUGCU


Sorted Z-values histogram for motif UAAUGCU

Sorted Z-values for motif UAAUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of UAAUGCU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_135502445 0.747 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
 MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr20_-_39317875 0.531 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr6_-_56112315 0.521 NM_030820
 COL21A1
collagen, type XXI, alpha 1
chr7_+_94285620 0.472 NM_001040152
NM_001184961
NM_001184962
NM_015068
 PEG10



paternally expressed 10



chr7_+_94285676 0.460 NM_001172437
NM_001172438
 PEG10

paternally expressed 10

chr15_-_89089792 0.408 NM_001144074
NM_017996
 DET1

de-etiolated homolog 1 (Arabidopsis)

chr11_-_27721975 0.350 NM_001143813
NM_001143814
NM_001709
 BDNF


brain-derived neurotrophic factor


chr17_+_4613780 0.342 NM_004313
NM_199004
 ARRB2

arrestin, beta 2

chr11_-_27742224 0.335 NM_001143805
NM_001143806
NM_170732
 BDNF


brain-derived neurotrophic factor


chr11_-_27741192 0.333 NM_001143807
 BDNF
brain-derived neurotrophic factor
chr17_-_47439326 0.332 NM_001145365
NM_014897
 ZNF652

zinc finger protein 652

chr11_+_111848008 0.331 NM_033425
 DIXDC1
DIX domain containing 1
chr1_+_183605207 0.328 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr2_-_233877920 0.327 NM_019850
 NGEF
neuronal guanine nucleotide exchange factor
chr6_-_134373618 0.319 NM_145176
 SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr11_-_27723061 0.319 NM_170733
 BDNF
brain-derived neurotrophic factor
chr18_-_53255734 0.317 NM_001083962
NM_001243230
NM_003199
 TCF4


transcription factor 4


chr10_+_83637442 0.315 NM_001165973
 NRG3
neuregulin 3
chr11_-_27743604 0.314 NM_170731
 BDNF
brain-derived neurotrophic factor
chr11_-_27722599 0.311 NM_001143808
NM_001143809
NM_001143810
NM_001143811
 BDNF



brain-derived neurotrophic factor




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
36.29 4.14e-02 GO:0034983 peptidyl-lysine deacetylation
3.75 1.07e-05 GO:0016568 chromatin modification
3.16 1.11e-04 GO:0006325 chromatin organization
2.89 2.56e-05 GO:0007167 enzyme linked receptor protein signaling pathway
2.59 1.87e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.52 6.85e-03 GO:0051276 chromosome organization
2.40 3.38e-02 GO:0010629 negative regulation of gene expression
2.26 1.27e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.21 9.90e-03 GO:0006351 transcription, DNA-dependent
1.93 8.69e-06 GO:0006355 regulation of transcription, DNA-dependent
1.91 9.38e-06 GO:0051252 regulation of RNA metabolic process
1.90 3.46e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.88 2.11e-06 GO:0010468 regulation of gene expression
1.85 1.21e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.76 7.96e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 7.96e-05 GO:0031326 regulation of cellular biosynthetic process
1.74 1.33e-04 GO:0009889 regulation of biosynthetic process
1.71 3.07e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.69 1.67e-05 GO:0060255 regulation of macromolecule metabolic process
1.60 2.63e-04 GO:0080090 regulation of primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
6.05 3.41e-02 GO:0016605 PML body
3.39 3.05e-03 GO:0005667 transcription factor complex
2.57 5.50e-05 GO:0044451 nucleoplasm part
2.13 2.56e-05 GO:0005654 nucleoplasm
2.09 2.25e-07 GO:0031981 nuclear lumen
1.91 2.02e-06 GO:0044428 nuclear part
1.76 1.11e-04 GO:0043233 organelle lumen
1.75 2.09e-04 GO:0070013 intracellular organelle lumen
1.73 2.13e-04 GO:0031974 membrane-enclosed lumen
1.58 5.14e-10 GO:0005634 nucleus
1.27 1.38e-04 GO:0043231 intracellular membrane-bounded organelle
1.27 1.52e-04 GO:0043227 membrane-bounded organelle
1.23 3.59e-04 GO:0043229 intracellular organelle
1.23 4.26e-04 GO:0043226 organelle
1.21 2.24e-05 GO:0044424 intracellular part
1.20 2.38e-05 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
38.71 2.56e-04 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
19.36 9.88e-03 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
6.92 1.80e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
5.33 2.04e-03 GO:0005057 receptor signaling protein activity
2.66 5.00e-08 GO:0001071 nucleic acid binding transcription factor activity
2.66 5.00e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
2.34 3.50e-03 GO:0043565 sequence-specific DNA binding
2.07 9.50e-10 GO:0003677 DNA binding
1.93 2.43e-02 GO:0030528 transcription regulator activity
1.84 4.90e-05 GO:0008270 zinc ion binding
1.75 1.12e-07 GO:0003676 nucleic acid binding
1.67 1.61e-03 GO:0046914 transition metal ion binding
1.46 2.61e-03 GO:0043167 ion binding
1.45 3.98e-03 GO:0043169 cation binding
1.45 4.05e-03 GO:0046872 metal ion binding
1.30 1.07e-03 GO:0005515 protein binding
1.20 1.01e-05 GO:0005488 binding