Motif ID: UCACAGU

Z-value: 0.761


Mature miRNA associated with seed UCACAGU:

NamemiRBase Accession
hsa-miR-27a MIMAT0000084
hsa-miR-27b MIMAT0000419



Activity profile for motif UCACAGU.

activity profile for motif UCACAGU


Sorted Z-values histogram for motif UCACAGU

Sorted Z-values for motif UCACAGU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_75139421 3.472 NM_001002912
 C1orf173
chromosome 1 open reading frame 173
chr6_-_24911194 3.310 NM_014722
 FAM65B
family with sequence similarity 65, member B
chr13_-_37494370 2.268 NM_001127217
NM_005905
 SMAD9

SMAD family member 9

chr3_+_13590624 2.186 NM_001004019
NM_001998
 FBLN2

fibulin 2

chr3_+_13610239 2.180 NM_001165035
 FBLN2
fibulin 2
chr14_+_67999915 2.103 NM_020715
 PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr6_-_56112315 2.000 NM_030820
 COL21A1
collagen, type XXI, alpha 1
chr16_-_53737713 1.821 NM_001127897
NM_015272
 RPGRIP1L

RPGRIP1-like

chr14_+_100259445 1.807 NM_001008707
NM_004434
 EML1

echinoderm microtubule associated protein like 1

chr1_+_61547625 1.790 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr1_+_61542928 1.742 NM_001145511
 NFIA
nuclear factor I/A
chr5_+_76506705 1.676 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
 PDE8B




phosphodiesterase 8B




chr5_+_50678957 1.616 NM_002202
 ISL1
ISL LIM homeobox 1
chr19_+_32897021 1.511 NM_207325
 DPY19L3
dpy-19-like 3 (C. elegans)
chr19_+_32896515 1.434 NM_001172774
 DPY19L3
dpy-19-like 3 (C. elegans)
chr14_+_56584854 1.431 NM_021255
 PELI2
pellino homolog 2 (Drosophila)
chr8_+_76452202 1.413 NM_004133
 HNF4G
hepatocyte nuclear factor 4, gamma
chr8_+_40010986 1.413 NM_020130
 C8orf4
chromosome 8 open reading frame 4
chr1_+_61547388 1.404 NM_001145512
 NFIA
nuclear factor I/A
chr1_-_92351613 1.372 NM_001195683
NM_003243
 TGFBR3

transforming growth factor, beta receptor III


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 52 entries
enrichment   p-value GO term description
2.95 6.52e-04 GO:0035295 tube development
2.56 2.36e-03 GO:0048598 embryonic morphogenesis
2.42 3.15e-02 GO:0007389 pattern specification process
2.35 3.67e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
2.33 9.03e-03 GO:0032583 regulation of gene-specific transcription
2.23 6.64e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.21 1.99e-02 GO:0072358 cardiovascular system development
2.21 1.99e-02 GO:0072359 circulatory system development
2.15 4.83e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.12 1.99e-03 GO:0051254 positive regulation of RNA metabolic process
2.10 2.62e-03 GO:0010628 positive regulation of gene expression
2.09 2.32e-03 GO:0009790 embryo development
2.09 3.03e-02 GO:0051253 negative regulation of RNA metabolic process
2.07 1.13e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.05 2.29e-02 GO:0010629 negative regulation of gene expression
2.03 3.48e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.01 2.79e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.98 2.69e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.95 3.83e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.88 2.05e-02 GO:0031328 positive regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
27.24 1.39e-02 GO:0009331 glycerol-3-phosphate dehydrogenase complex
1.85 1.46e-02 GO:0044451 nucleoplasm part
1.46 4.36e-02 GO:0031981 nuclear lumen
1.29 6.67e-04 GO:0005634 nucleus
1.11 2.22e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
27.24 2.04e-02 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity
4.81 3.71e-02 GO:0003707 steroid hormone receptor activity
3.89 2.33e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
2.83 7.85e-03 GO:0000975 regulatory region DNA binding
2.83 7.85e-03 GO:0001067 regulatory region nucleic acid binding
2.83 7.85e-03 GO:0044212 transcription regulatory region DNA binding
2.81 1.39e-02 GO:0010843 promoter binding
2.57 1.60e-03 GO:0016563 transcription activator activity
2.54 2.77e-03 GO:0016564 transcription repressor activity
2.48 9.30e-03 GO:0008134 transcription factor binding
2.29 6.00e-06 GO:0043565 sequence-specific DNA binding
2.25 1.47e-02 GO:0003712 transcription cofactor activity
2.24 1.55e-02 GO:0000988 protein binding transcription factor activity
2.24 1.55e-02 GO:0000989 transcription factor binding transcription factor activity
2.13 1.83e-02 GO:0019904 protein domain specific binding
2.09 8.17e-07 GO:0030528 transcription regulator activity
2.05 3.73e-06 GO:0001071 nucleic acid binding transcription factor activity
2.05 3.73e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.45 9.35e-03 GO:0003677 DNA binding
1.19 4.20e-02 GO:0005515 protein binding