Motif ID: UCACAUU

Z-value: 0.561


Mature miRNA associated with seed UCACAUU:

NamemiRBase Accession
hsa-miR-23a MIMAT0000078
hsa-miR-23b MIMAT0000418
hsa-miR-23c MIMAT0018000



Activity profile for motif UCACAUU.

activity profile for motif UCACAUU


Sorted Z-values histogram for motif UCACAUU

Sorted Z-values for motif UCACAUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_136834887 1.872 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr2_-_1748285 1.370 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr6_+_151646634 1.038 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_90728118 1.025 NM_020210
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_35696359 1.025 NM_001145775
FKBP5
FK506 binding protein 5
chr6_+_151561094 0.911 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr6_-_35656677 0.807 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr15_+_90744506 0.733 NM_198925
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr20_+_1875382 0.627 NM_080792
SIRPA
signal-regulatory protein alpha
chr20_+_1875825 0.621 NM_001040023
SIRPA
signal-regulatory protein alpha
chr20_+_1874779 0.597 NM_001040022
SIRPA
signal-regulatory protein alpha
chr2_+_102314162 0.582 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr5_+_34684611 0.560 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chrX_+_115567746 0.557 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr8_+_86376130 0.556 NM_000067
CA2
carbonic anhydrase II
chr17_+_60704747 0.537 NM_006039
MRC2
mannose receptor, C type 2
chr15_+_63481713 0.500 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr8_-_28243941 0.477 NM_018660
ZNF395
zinc finger protein 395
chr10_+_11206928 0.473 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr9_-_113800243 0.471 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr5_+_34687663 0.471 NM_001145523
RAI14
retinoic acid induced 14
chr5_-_77944341 0.448 NM_005779
LHFPL2
lipoma HMGIC fusion partner-like 2
chr4_+_1873035 0.446 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr19_+_1026271 0.427 NM_004368
NM_201277
CNN2

calponin 2

chr13_+_98605928 0.421 NM_002271
IPO5
importin 5
chr12_+_32654976 0.415 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_+_127054246 0.391 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr4_+_1894508 0.391 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr9_+_127054567 0.389 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr10_+_11047253 0.388 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr6_+_15246299 0.381 NM_004973
JARID2
jumonji, AT rich interactive domain 2
chr11_-_88796815 0.373 NM_000842
GRM5
glutamate receptor, metabotropic 5
chr5_+_34656595 0.361 NM_001145520
RAI14
retinoic acid induced 14
chr5_+_149887673 0.345 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr5_+_34656367 0.336 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr2_-_208634051 0.335 NM_003468
FZD5
frizzled family receptor 5
chr11_-_88781039 0.335 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chr10_+_11059854 0.334 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr3_-_87040246 0.328 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr8_+_126442557 0.320 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr1_+_154377668 0.314 NM_000565
NM_001206866
NM_181359
IL6R


interleukin 6 receptor


chr14_+_103058988 0.313 NM_015156
RCOR1
REST corepressor 1
chr5_+_40680021 0.303 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr9_+_127020462 0.301 NM_001166168
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr4_+_144257982 0.298 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr3_-_113465101 0.291 NM_025146
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr15_-_56209305 0.290 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr6_+_114178516 0.290 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chrX_-_138914384 0.288 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr9_+_127019782 0.284 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr1_+_28585959 0.284 NM_031459
SESN2
sestrin 2
chr2_-_47143250 0.280 NM_001171507
NM_001171510
MCFD2

multiple coagulation factor deficiency 2

chr8_-_60031545 0.280 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr8_-_66701175 0.277 NM_002603
PDE7A
phosphodiesterase 7A
chr12_-_80307690 0.274 NM_001143886
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr1_-_211307314 0.272 NM_002238
NM_172362
KCNH1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr17_+_1958354 0.272 NM_006497
HIC1
hypermethylated in cancer 1
chr19_+_45971249 0.270 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr2_-_101034049 0.264 NM_004854
CHST10
carbohydrate sulfotransferase 10
chr12_-_48298765 0.263 NM_000376
NM_001017535
NM_001017536
VDR


vitamin D (1,25- dihydroxyvitamin D3) receptor


chr16_-_79634610 0.263 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chrX_-_6145887 0.257 NM_020742
NLGN4X
neuroligin 4, X-linked
chr12_-_95044205 0.256 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr15_-_56285732 0.253 NM_006154
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr12_-_69357019 0.252 NM_001874
CPM
carboxypeptidase M
chr2_-_47142950 0.250 NM_001171506
NM_001171509
NM_139279
MCFD2


multiple coagulation factor deficiency 2


chr2_-_172087823 0.247 NM_001136554
TLK1
tousled-like kinase 1
chr2_-_171923482 0.244 NM_001136555
TLK1
tousled-like kinase 1
chr17_-_73851377 0.240 NM_012478
WBP2
WW domain binding protein 2
chr17_+_1959512 0.240 NM_001098202
HIC1
hypermethylated in cancer 1
chr8_-_93075190 0.238 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_47168902 0.235 NM_001171508
NM_001171511
MCFD2

multiple coagulation factor deficiency 2

chrX_-_6146655 0.234 NM_181332
NLGN4X
neuroligin 4, X-linked
chr12_-_69326946 0.234 NM_001005502
NM_198320
CPM

carboxypeptidase M

chr1_-_68962726 0.233 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr12_-_80329234 0.229 NM_001143885
NM_001244990
PPP1R12A

protein phosphatase 1, regulatory subunit 12A

chr14_+_94640648 0.224 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr8_+_79428335 0.224 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr1_+_82266081 0.222 NM_012302
LPHN2
latrophilin 2
chr3_-_138665981 0.216 NM_023067
FOXL2
forkhead box L2
chr8_-_124544376 0.214 NM_148177
FBXO32
F-box protein 32
chr16_-_48644087 0.206 NM_153029
N4BP1
NEDD4 binding protein 1
chr12_+_104850641 0.205 NM_001173982
NM_018413
CHST11

carbohydrate (chondroitin 4) sulfotransferase 11

chr4_+_120133764 0.204 NM_019050
USP53
ubiquitin specific peptidase 53
chr12_-_80328926 0.203 NM_002480
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr9_-_14910992 0.202 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr17_+_45608443 0.202 NM_006310
NPEPPS
aminopeptidase puromycin sensitive
chr2_-_70781146 0.199 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr10_+_134351272 0.198 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr20_-_17949384 0.197 NM_152227
SNX5
sorting nexin 5
chr6_-_82462374 0.197 NM_017633
FAM46A
family with sequence similarity 46, member A
chr4_+_166248816 0.196 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr2_-_172017358 0.196 NM_012290
TLK1
tousled-like kinase 1
chr6_+_106534188 0.194 NM_001198
PRDM1
PR domain containing 1, with ZNF domain
chr14_-_35182944 0.193 NM_021914
CFL2
cofilin 2 (muscle)
chr13_+_113951461 0.191 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr9_+_33817168 0.188 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr15_+_40509628 0.188 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr11_-_102962903 0.188 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr14_+_39734475 0.187 NM_203354
CTAGE5
CTAGE family, member 5
chr9_-_14779530 0.182 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr8_-_93029864 0.182 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_160068617 0.182 NM_001206665
IGSF8
immunoglobulin superfamily, member 8
chr14_-_74485813 0.182 NM_001249
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr14_-_35183722 0.179 NM_001243645
NM_138638
CFL2

cofilin 2 (muscle)

chr12_-_105478218 0.179 NM_001034173
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr8_-_124553448 0.177 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr10_+_75670861 0.176 NM_001145031
NM_002658
PLAU

plasminogen activator, urokinase

chr8_-_93111915 0.176 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_160068359 0.172 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr13_-_52027274 0.169 NM_001039937
NM_001039938
NM_012141
INTS6


integrator complex subunit 6


chr17_-_40761404 0.168 NM_178126
FAM134C
family with sequence similarity 134, member C
chr16_+_58498725 0.167 NM_022910
NDRG4
NDRG family member 4
chr14_+_67707825 0.164 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr4_+_155665150 0.163 NM_004744
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr8_-_122653493 0.161 NM_005328
HAS2
hyaluronan synthase 2
chr16_+_58497548 0.161 NM_020465
NDRG4
NDRG family member 4
chr2_-_228029274 0.160 NM_000092
COL4A4
collagen, type IV, alpha 4
chr14_+_39736277 0.160 NM_001247989
NM_001247990
NM_005930
NM_203355
CTAGE5



CTAGE family, member 5



chr4_-_174254730 0.158 NM_001130689
HMGB2
high mobility group box 2
chr16_+_24740945 0.158 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr3_+_30647901 0.157 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr16_+_58497993 0.156 NM_001130487
NDRG4
NDRG family member 4
chr8_-_125740650 0.154 NM_014751
MTSS1
metastasis suppressor 1
chr17_-_29151724 0.151 NM_015986
CRLF3
cytokine receptor-like factor 3
chrX_+_44732402 0.148 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chrX_-_30907408 0.148 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr12_+_123868608 0.147 NM_020382
SETD8
SET domain containing (lysine methyltransferase) 8
chr16_+_27438578 0.146 NM_021798
IL21R
interleukin 21 receptor
chr15_+_83477972 0.146 NM_001080435
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr6_+_138188352 0.145 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_46972667 0.144 NM_147192
NM_172225
DMBX1

diencephalon/mesencephalon homeobox 1

chr10_+_60094712 0.143 NM_001204880
NM_003338
UBE2D1

ubiquitin-conjugating enzyme E2D 1

chr18_-_48724031 0.143 NM_016626
MEX3C
mex-3 homolog C (C. elegans)
chr6_+_106546736 0.141 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr1_-_154155698 0.141 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr2_-_37193609 0.140 NM_003162
STRN
striatin, calmodulin binding protein
chr11_+_133938819 0.139 NM_001205329
NM_032801
JAM3

junctional adhesion molecule 3

chr3_+_147127151 0.138 NM_003412
ZIC1
Zic family member 1
chr14_+_37126772 0.138 NM_006194
PAX9
paired box 9
chr8_-_55014367 0.137 NM_006330
LYPLA1
lysophospholipase I
chr1_+_53192021 0.135 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr1_+_23037329 0.134 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr20_+_43595119 0.133 NM_006282
STK4
serine/threonine kinase 4
chr13_-_30169795 0.133 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr15_-_30114536 0.133 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr1_-_231560789 0.131 NM_022051
EGLN1
egl nine homolog 1 (C. elegans)
chr6_+_121756744 0.130 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr9_-_19102898 0.130 NM_017645
HAUS6
HAUS augmin-like complex, subunit 6
chr12_+_104324186 0.129 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chrX_-_129244471 0.129 NM_001421
ELF4
E74-like factor 4 (ets domain transcription factor)
chr18_-_31628557 0.128 NM_001198549
NOL4
nucleolar protein 4
chrX_-_41782230 0.127 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chrX_-_129244652 0.126 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr9_+_4490193 0.124 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_+_191745546 0.121 NM_014905
GLS
glutaminase
chr17_+_61086897 0.121 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr18_+_9913954 0.121 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr9_+_129567260 0.120 NM_001135776
NM_014007
ZBTB43

zinc finger and BTB domain containing 43

chr11_+_69455837 0.120 NM_053056
CCND1
cyclin D1
chr7_-_14030864 0.119 NM_001163149
ETV1
ets variant 1
chr3_-_98620452 0.117 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr7_-_14031049 0.116 NM_001163148
ETV1
ets variant 1
chr17_-_16472463 0.116 NM_020653
ZNF287
zinc finger protein 287
chr11_+_86748870 0.114 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr9_-_95527002 0.112 NM_001003800
NM_015250
BICD2

bicaudal D homolog 2 (Drosophila)

chr6_+_105404922 0.112 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr5_-_148442606 0.112 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr4_+_15004297 0.112 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr18_-_31803514 0.112 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr16_+_58534045 0.109 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr9_-_95432542 0.109 NM_022755
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr13_-_80915041 0.108 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr20_-_17949067 0.108 NM_014426
SNX5
sorting nexin 5
chr18_-_31802433 0.107 NM_001198547
NOL4
nucleolar protein 4
chr17_+_78518611 0.107 NM_001163034
NM_020761
RPTOR

regulatory associated protein of MTOR, complex 1

chr14_+_55518313 0.106 NM_144578
MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr1_-_240775448 0.104 NM_022469
GREM2
gremlin 2
chr12_-_54653369 0.104 NM_001127321
CBX5
chromobox homolog 5
chr16_-_15982446 0.104 NM_144600
FOPNL
FGFR1OP N-terminal like
chr6_+_96463844 0.103 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr7_+_4721722 0.103 NM_001037165
FOXK1
forkhead box K1
chr9_+_110045516 0.102 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr4_-_174255454 0.101 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr5_-_78282356 0.101 NM_000046
ARSB
arylsulfatase B
chrX_-_63425484 0.100 NM_152424
FAM123B
family with sequence similarity 123B
chr7_+_38217807 0.100 NM_032016
STARD3NL
STARD3 N-terminal like
chr1_-_27816676 0.100 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr14_+_102786083 0.099 NM_018335
ZNF839
zinc finger protein 839
chr3_-_71778268 0.099 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr1_+_90098643 0.098 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr5_+_72112417 0.098 NM_002270
TNPO1
transportin 1
chr8_+_27179918 0.098 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr12_-_46663207 0.097 NM_001077484
NM_030674
SLC38A1

solute carrier family 38, member 1

chr15_+_67358194 0.097 NM_005902
SMAD3
SMAD family member 3
chr8_-_66753968 0.096 NM_001242318
PDE7A
phosphodiesterase 7A
chr2_+_28974608 0.096 NM_206876
NM_002709
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr8_-_131455833 0.095 NM_001247996
NM_018482
ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain 1

chr1_-_214724974 0.095 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr8_+_77593506 0.094 NM_024721
ZFHX4
zinc finger homeobox 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.68 5.55e-09 GO:0080090 regulation of primary metabolic process
1.66 1.73e-08 GO:0031323 regulation of cellular metabolic process
1.61 3.02e-08 GO:0019222 regulation of metabolic process
1.66 9.67e-08 GO:0060255 regulation of macromolecule metabolic process
1.38 1.65e-07 GO:0050794 regulation of cellular process
1.35 2.81e-07 GO:0050789 regulation of biological process
1.32 1.53e-06 GO:0065007 biological regulation
1.70 1.01e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.70 1.74e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.65 2.46e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 2.47e-05 GO:0009889 regulation of biosynthetic process
1.70 3.39e-05 GO:0048519 negative regulation of biological process
2.44 4.59e-05 GO:0019220 regulation of phosphate metabolic process
2.44 4.59e-05 GO:0051174 regulation of phosphorus metabolic process
1.64 4.68e-05 GO:0031326 regulation of cellular biosynthetic process
2.46 5.31e-05 GO:0042325 regulation of phosphorylation
1.65 5.35e-05 GO:0010468 regulation of gene expression
1.80 6.47e-05 GO:0006464 protein modification process
1.85 9.52e-05 GO:0023051 regulation of signaling
2.12 1.02e-04 GO:0006793 phosphorus metabolic process
2.12 1.02e-04 GO:0006796 phosphate metabolic process
1.91 1.19e-04 GO:0009966 regulation of signal transduction
1.60 1.35e-04 GO:0051171 regulation of nitrogen compound metabolic process
2.69 1.57e-04 GO:0043549 regulation of kinase activity
2.72 1.73e-04 GO:0045859 regulation of protein kinase activity
2.04 2.17e-04 GO:0051246 regulation of protein metabolic process
2.88 2.68e-04 GO:0010627 regulation of intracellular protein kinase cascade
1.86 3.03e-04 GO:0007399 nervous system development
2.59 3.74e-04 GO:0051338 regulation of transferase activity
1.66 3.99e-04 GO:0051252 regulation of RNA metabolic process
1.67 4.52e-04 GO:0048523 negative regulation of cellular process
2.38 5.05e-04 GO:0001932 regulation of protein phosphorylation
1.71 6.89e-04 GO:0043412 macromolecule modification
2.03 7.63e-04 GO:0032268 regulation of cellular protein metabolic process
1.65 8.20e-04 GO:0006355 regulation of transcription, DNA-dependent
2.17 9.84e-04 GO:0031399 regulation of protein modification process
2.69 1.18e-03 GO:0007243 intracellular protein kinase cascade
2.69 1.18e-03 GO:0023014 signal transduction via phosphorylation event
7.88 2.52e-03 GO:0018105 peptidyl-serine phosphorylation
1.44 2.86e-03 GO:0023052 signaling
3.02 2.92e-03 GO:0071900 regulation of protein serine/threonine kinase activity
1.54 3.28e-03 GO:0048518 positive regulation of biological process
1.52 3.80e-03 GO:0048731 system development
3.15 3.94e-03 GO:0000165 MAPKKK cascade
2.15 4.36e-03 GO:0006468 protein phosphorylation
2.31 5.81e-03 GO:0048666 neuron development
2.26 6.96e-03 GO:0010629 negative regulation of gene expression
1.37 7.05e-03 GO:0044260 cellular macromolecule metabolic process
2.02 9.05e-03 GO:0016310 phosphorylation
2.56 1.09e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.38 1.13e-02 GO:0031175 neuron projection development
1.88 1.16e-02 GO:0010646 regulation of cell communication
1.46 1.19e-02 GO:0048856 anatomical structure development
1.54 1.20e-02 GO:0048522 positive regulation of cellular process
1.79 1.33e-02 GO:0009893 positive regulation of metabolic process
1.43 1.36e-02 GO:0007165 signal transduction
1.72 1.38e-02 GO:0009653 anatomical structure morphogenesis
6.51 1.38e-02 GO:0018209 peptidyl-serine modification
2.18 1.51e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.15 1.55e-02 GO:0007167 enzyme linked receptor protein signaling pathway
4.32 1.68e-02 GO:0070302 regulation of stress-activated protein kinase signaling cascade
3.31 1.69e-02 GO:0043408 regulation of MAPKKK cascade
2.14 1.74e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.60 2.71e-02 GO:0048583 regulation of response to stimulus
2.71 2.88e-02 GO:0045860 positive regulation of protein kinase activity
2.07 3.05e-02 GO:0009890 negative regulation of biosynthetic process
1.78 3.21e-02 GO:0050790 regulation of catalytic activity
1.79 3.22e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.41 3.30e-02 GO:0007275 multicellular organismal development
1.90 3.48e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.36 3.70e-02 GO:0051716 cellular response to stimulus
4.29 3.97e-02 GO:0046328 regulation of JNK cascade
2.06 4.38e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.14 4.43e-02 GO:0009987 cellular process
2.58 4.47e-02 GO:0009894 regulation of catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.24e-06 GO:0005622 intracellular
1.19 1.66e-06 GO:0044424 intracellular part
1.38 6.83e-06 GO:0005634 nucleus
1.24 1.89e-05 GO:0043231 intracellular membrane-bounded organelle
1.24 2.16e-05 GO:0043227 membrane-bounded organelle
1.20 1.02e-04 GO:0043229 intracellular organelle
1.20 1.27e-04 GO:0043226 organelle
6.49 6.65e-03 GO:0008287 protein serine/threonine phosphatase complex
1.07 9.27e-03 GO:0044464 cell part
1.07 9.42e-03 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 5.43e-07 GO:0005488 binding
1.28 9.10e-05 GO:0005515 protein binding
2.07 2.36e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.18 2.71e-03 GO:0004672 protein kinase activity
3.43 4.13e-03 GO:0000287 magnesium ion binding
1.90 5.60e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.97 6.12e-03 GO:0016301 kinase activity
1.83 1.04e-02 GO:0001071 nucleic acid binding transcription factor activity
1.83 1.04e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.30 1.21e-02 GO:0004674 protein serine/threonine kinase activity
1.93 2.05e-02 GO:0019899 enzyme binding
2.20 3.58e-02 GO:0019904 protein domain specific binding