Motif ID: UCACAUU

Z-value: 0.561


Mature miRNA associated with seed UCACAUU:

NamemiRBase Accession
hsa-miR-23a MIMAT0000078
hsa-miR-23b MIMAT0000418
hsa-miR-23c MIMAT0018000



Activity profile for motif UCACAUU.

activity profile for motif UCACAUU


Sorted Z-values histogram for motif UCACAUU

Sorted Z-values for motif UCACAUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCACAUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_136834887 1.872 NM_004598
 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr2_-_1748285 1.370 NM_012293
 PXDN
peroxidasin homolog (Drosophila)
chr6_+_151646634 1.038 NM_144497
 AKAP12
A kinase (PRKA) anchor protein 12
chr15_+_90728118 1.025 NM_020210
 SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_35696359 1.025 NM_001145775
 FKBP5
FK506 binding protein 5
chr6_+_151561094 0.911 NM_005100
 AKAP12
A kinase (PRKA) anchor protein 12
chr6_-_35656677 0.807 NM_001145776
NM_001145777
NM_004117
 FKBP5


FK506 binding protein 5


chr15_+_90744506 0.733 NM_198925
 SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr20_+_1875382 0.627 NM_080792
 SIRPA
signal-regulatory protein alpha
chr20_+_1875825 0.621 NM_001040023
 SIRPA
signal-regulatory protein alpha
chr20_+_1874779 0.597 NM_001040022
 SIRPA
signal-regulatory protein alpha
chr2_+_102314162 0.582 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
 MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr5_+_34684611 0.560 NM_001145521
NM_001145525
 RAI14

retinoic acid induced 14

chrX_+_115567746 0.557 NM_007231
 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr8_+_86376130 0.556 NM_000067
 CA2
carbonic anhydrase II
chr17_+_60704747 0.537 NM_006039
 MRC2
mannose receptor, C type 2
chr15_+_63481713 0.500 NM_016530
 RAB8B
RAB8B, member RAS oncogene family
chr8_-_28243941 0.477 NM_018660
 ZNF395
zinc finger protein 395
chr10_+_11206928 0.473 NM_001025076
NM_001083591
 CELF2

CUGBP, Elav-like family member 2

chr9_-_113800243 0.471 NM_001401
NM_057159
 LPAR1

lysophosphatidic acid receptor 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 75 entries
enrichment   p-value GO term description
7.88 2.52e-03 GO:0018105 peptidyl-serine phosphorylation
6.51 1.38e-02 GO:0018209 peptidyl-serine modification
4.32 1.68e-02 GO:0070302 regulation of stress-activated protein kinase signaling cascade
4.29 3.97e-02 GO:0046328 regulation of JNK cascade
3.31 1.69e-02 GO:0043408 regulation of MAPKKK cascade
3.15 3.94e-03 GO:0000165 MAPKKK cascade
3.02 2.92e-03 GO:0071900 regulation of protein serine/threonine kinase activity
2.88 2.68e-04 GO:0010627 regulation of intracellular protein kinase cascade
2.72 1.73e-04 GO:0045859 regulation of protein kinase activity
2.71 2.88e-02 GO:0045860 positive regulation of protein kinase activity
2.69 1.57e-04 GO:0043549 regulation of kinase activity
2.69 1.18e-03 GO:0007243 intracellular protein kinase cascade
2.69 1.18e-03 GO:0023014 signal transduction via phosphorylation event
2.59 3.74e-04 GO:0051338 regulation of transferase activity
2.58 4.47e-02 GO:0009894 regulation of catabolic process
2.56 1.09e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.46 5.31e-05 GO:0042325 regulation of phosphorylation
2.44 4.59e-05 GO:0019220 regulation of phosphate metabolic process
2.44 4.59e-05 GO:0051174 regulation of phosphorus metabolic process
2.38 5.05e-04 GO:0001932 regulation of protein phosphorylation

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
6.49 6.65e-03 GO:0008287 protein serine/threonine phosphatase complex
1.38 6.83e-06 GO:0005634 nucleus
1.24 1.89e-05 GO:0043231 intracellular membrane-bounded organelle
1.24 2.16e-05 GO:0043227 membrane-bounded organelle
1.20 1.02e-04 GO:0043229 intracellular organelle
1.20 1.27e-04 GO:0043226 organelle
1.19 1.66e-06 GO:0044424 intracellular part
1.18 1.24e-06 GO:0005622 intracellular
1.07 9.27e-03 GO:0044464 cell part
1.07 9.42e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
3.43 4.13e-03 GO:0000287 magnesium ion binding
2.30 1.21e-02 GO:0004674 protein serine/threonine kinase activity
2.20 3.58e-02 GO:0019904 protein domain specific binding
2.18 2.71e-03 GO:0004672 protein kinase activity
2.07 2.36e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.97 6.12e-03 GO:0016301 kinase activity
1.93 2.05e-02 GO:0019899 enzyme binding
1.90 5.60e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.83 1.04e-02 GO:0001071 nucleic acid binding transcription factor activity
1.83 1.04e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 9.10e-05 GO:0005515 protein binding
1.18 5.43e-07 GO:0005488 binding