Motif ID: UCCAGUU

Z-value: 0.662


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145 MIMAT0000437



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_151646634 2.234 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr6_+_151561094 2.203 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr8_+_26371461 1.260 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr8_+_26435339 1.152 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr7_+_5632435 1.023 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr10_-_74856656 0.927 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr20_-_25566137 0.853 NM_025176
NINL
ninein-like
chr7_-_83824216 0.792 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_144385647 0.785 NM_001080951
NM_001080955
PLAGL1

pleiomorphic adenoma gene-like 1

chr7_+_130126035 0.772 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr3_+_57994087 0.764 NM_001164317
NM_001164318
NM_001164319
NM_001457
FLNB



filamin B, beta



chr12_-_89746244 0.757 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr6_-_144329342 0.747 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr10_+_112404104 0.737 NM_001134363
RBM20
RNA binding motif protein 20
chr17_+_70117154 0.734 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr6_-_11382501 0.725 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr22_+_38035683 0.718 NM_018957
SH3BP1
SH3-domain binding protein 1
chr9_+_128509616 0.703 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr15_-_52821004 0.702 NM_000259
NM_001142495
MYO5A

myosin VA (heavy chain 12, myoxin)

chr9_+_128510477 0.696 NM_001134778
PBX3
pre-B-cell leukemia homeobox 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
20.20 3.28e-02 GO:0007183 SMAD protein complex assembly
6.50 1.21e-02 GO:0010810 regulation of cell-substrate adhesion
4.25 3.60e-02 GO:0007265 Ras protein signal transduction
2.83 7.44e-03 GO:0051056 regulation of small GTPase mediated signal transduction
2.20 3.91e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.04 5.64e-05 GO:0009966 regulation of signal transduction
1.94 8.52e-05 GO:0023051 regulation of signaling
1.71 7.92e-03 GO:0048583 regulation of response to stimulus
1.46 7.48e-03 GO:0023052 signaling
1.29 4.76e-04 GO:0065007 biological regulation
1.29 1.67e-03 GO:0050789 regulation of biological process
1.29 7.75e-03 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
5.05 4.58e-02 GO:0031256 leading edge membrane
4.81 1.11e-02 GO:0030027 lamellipodium
4.54 1.83e-02 GO:0001726 ruffle
4.29 2.83e-05 GO:0031252 cell leading edge
2.03 4.12e-03 GO:0042995 cell projection
1.22 6.18e-03 GO:0005737 cytoplasm
1.21 2.70e-07 GO:0005622 intracellular
1.20 7.11e-06 GO:0044424 intracellular part
1.08 1.28e-02 GO:0044464 cell part
1.08 1.30e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
24.24 4.25e-02 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
16.16 2.03e-02 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
3.12 8.17e-04 GO:0005083 small GTPase regulator activity
3.09 4.58e-03 GO:0005096 GTPase activator activity
2.96 1.18e-03 GO:0003779 actin binding
2.73 2.22e-04 GO:0030695 GTPase regulator activity
2.66 3.86e-04 GO:0060589 nucleoside-triphosphatase regulator activity
2.36 4.32e-03 GO:0008092 cytoskeletal protein binding
1.90 1.56e-02 GO:0030234 enzyme regulator activity
1.28 6.23e-04 GO:0005515 protein binding
1.13 2.58e-02 GO:0005488 binding