Motif ID: UGUGCUU

Z-value: 0.927


Mature miRNA associated with seed UGUGCUU:

NamemiRBase Accession
hsa-miR-218 MIMAT0000275



Activity profile for motif UGUGCUU.

activity profile for motif UGUGCUU


Sorted Z-values histogram for motif UGUGCUU

Sorted Z-values for motif UGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UGUGCUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_24911194 1.595 NM_014722
FAM65B
family with sequence similarity 65, member B
chr6_-_132272311 1.414 NM_001901
CTGF
connective tissue growth factor
chr7_-_37024664 1.382 NM_001039459
ELMO1
engulfment and cell motility 1
chr7_-_37393271 1.339 NM_001206482
ELMO1
engulfment and cell motility 1
chr7_-_37488554 1.336 NM_014800
ELMO1
engulfment and cell motility 1
chr7_-_37488894 1.283 NM_001206480
ELMO1
engulfment and cell motility 1
chr4_-_154710207 1.133 NM_003013
SFRP2
secreted frizzled-related protein 2
chr6_+_69344939 1.122 NM_001704
BAI3
brain-specific angiogenesis inhibitor 3
chr20_-_41818464 1.105 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr2_-_213403280 1.008 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr12_-_131002409 0.935 NM_015347
RIMBP2
RIMS binding protein 2
chr11_+_8102691 0.931 NM_177972
TUB
tubby homolog (mouse)
chr18_-_6414900 0.868 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr1_-_200992824 0.867 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr14_+_92790151 0.831 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 0.818 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_13218777 0.810 NM_181481
NM_181482
C18orf1

chromosome 18 open reading frame 1

chr2_+_191014971 0.795 NM_001042520
C2orf88
chromosome 2 open reading frame 88
chr14_+_53019865 0.790 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr17_+_53342320 0.767 NM_002126
HLF
hepatic leukemia factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
2.80 2.92e-05 GO:0007268 synaptic transmission
2.66 6.78e-03 GO:0007411 axon guidance
2.63 6.72e-05 GO:0019226 transmission of nerve impulse
2.63 6.72e-05 GO:0031175 neuron projection development
2.63 6.72e-05 GO:0035637 multicellular organismal signaling
2.55 6.96e-07 GO:0030182 neuron differentiation
2.53 1.23e-03 GO:0048812 neuron projection morphogenesis
2.51 3.04e-03 GO:0007409 axonogenesis
2.50 2.35e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
2.47 7.38e-04 GO:0000904 cell morphogenesis involved in differentiation
2.46 6.37e-08 GO:0048699 generation of neurons
2.45 1.58e-04 GO:0048666 neuron development
2.43 1.13e-03 GO:0007417 central nervous system development
2.37 2.88e-03 GO:0032990 cell part morphogenesis
2.32 7.19e-07 GO:0022008 neurogenesis
2.32 6.18e-03 GO:0048858 cell projection morphogenesis
2.30 2.31e-12 GO:0007399 nervous system development
2.30 1.15e-03 GO:0000902 cell morphogenesis
2.23 6.66e-06 GO:0048468 cell development
2.18 4.35e-03 GO:0032989 cellular component morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
8.24 1.82e-02 GO:0043596 nuclear replication fork
4.52 1.66e-03 GO:0008021 synaptic vesicle
3.46 1.76e-07 GO:0044456 synapse part
3.43 3.15e-10 GO:0045202 synapse
2.37 3.93e-03 GO:0043005 neuron projection
2.03 1.02e-02 GO:0030054 cell junction
1.44 4.59e-02 GO:0044459 plasma membrane part
1.06 4.55e-02 GO:0044464 cell part
1.06 4.62e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
15.11 2.88e-02 GO:0030371 translation repressor activity
1.86 2.20e-03 GO:0001071 nucleic acid binding transcription factor activity
1.86 2.20e-03 GO:0003700 sequence-specific DNA binding transcription factor activity