Motif ID: UUGUUCG

Z-value: 0.806


Mature miRNA associated with seed UUGUUCG:

NamemiRBase Accession
hsa-miR-375 MIMAT0000728



Activity profile for motif UUGUUCG.

activity profile for motif UUGUUCG


Sorted Z-values histogram for motif UUGUUCG

Sorted Z-values for motif UUGUUCG



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGUUCG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_137475076 1.897 NM_003551
 NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr4_+_72052354 1.799 NM_001098484
NM_001134742
 SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr1_+_38022514 1.509 NM_003462
 DNALI1
dynein, axonemal, light intermediate chain 1
chr13_+_36050885 1.486 NM_001204197
 NBEA
neurobeachin
chr14_+_74486049 1.420 NM_025057
 C14orf45
chromosome 14 open reading frame 45
chr1_+_78956727 1.363 NM_000959
NM_001039585
 PTGFR

prostaglandin F receptor (FP)

chr17_+_7761063 1.288 NM_144607
 CYB5D1
cytochrome b5 domain containing 1
chr13_+_35516390 1.213 NM_015678
 NBEA
neurobeachin
chr7_-_131241321 1.144 NM_001018111
NM_005397
 PODXL

podocalyxin-like

chr4_+_72204769 1.079 NM_003759
 SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr7_-_102715014 0.986 NM_145032
 FBXL13
F-box and leucine-rich repeat protein 13
chr14_+_74111577 0.953 NM_001201366
NM_031427
 DNAL1

dynein, axonemal, light chain 1

chr7_-_102715171 0.901 NM_001111038
 FBXL13
F-box and leucine-rich repeat protein 13
chr3_-_45883562 0.888 NM_020347
 LZTFL1
leucine zipper transcription factor-like 1
chr1_+_18807423 0.886 NM_152375
 KLHDC7A
kelch domain containing 7A
chr6_-_80247103 0.869 NM_001122769
NM_181714
 LCA5

Leber congenital amaurosis 5

chr4_+_95679075 0.833 NM_001203
 BMPR1B
bone morphogenetic protein receptor, type IB
chr6_-_132272311 0.796 NM_001901
 CTGF
connective tissue growth factor
chr1_-_236445294 0.765 NM_019891
 ERO1LB
ERO1-like beta (S. cerevisiae)
chr20_+_9049660 0.760 NM_001172646
 PLCB4
phospholipase C, beta 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
35.93 3.31e-02 GO:0021563 glossopharyngeal nerve development
35.93 3.31e-02 GO:0021615 glossopharyngeal nerve morphogenesis
2.89 3.73e-02 GO:0001568 blood vessel development
2.82 3.40e-02 GO:0001944 vasculature development
2.61 2.12e-02 GO:0009792 embryo development ending in birth or egg hatching
2.59 2.46e-03 GO:0072358 cardiovascular system development
2.59 2.46e-03 GO:0072359 circulatory system development
1.75 1.23e-02 GO:0009653 anatomical structure morphogenesis
1.66 1.26e-02 GO:0006464 protein modification process
1.62 2.44e-02 GO:0043412 macromolecule modification
1.41 1.77e-03 GO:0044260 cellular macromolecule metabolic process
1.41 4.90e-02 GO:0080090 regulation of primary metabolic process
1.29 9.53e-03 GO:0044237 cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.31 2.70e-03 GO:0005634 nucleus
1.29 6.77e-03 GO:0044446 intracellular organelle part
1.28 1.12e-02 GO:0044422 organelle part
1.26 6.95e-06 GO:0043231 intracellular membrane-bounded organelle
1.26 7.93e-06 GO:0043227 membrane-bounded organelle
1.23 4.68e-06 GO:0043229 intracellular organelle
1.23 5.92e-06 GO:0043226 organelle
1.19 1.85e-06 GO:0044424 intracellular part
1.18 1.10e-05 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
11.23 1.93e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
5.39 1.37e-02 GO:0004221 ubiquitin thiolesterase activity
1.78 3.73e-02 GO:0030528 transcription regulator activity
1.22 1.93e-02 GO:0005515 protein binding
1.15 9.29e-04 GO:0005488 binding