Motif ID: UUUUUGC

Z-value: 2.205


Mature miRNA associated with seed UUUUUGC:

NamemiRBase Accession
hsa-miR-129-5p MIMAT0000242



Activity profile for motif UUUUUGC.

activity profile for motif UUUUUGC


Sorted Z-values histogram for motif UUUUUGC

Sorted Z-values for motif UUUUUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUUUUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_24911194 10.867 NM_014722
FAM65B
family with sequence similarity 65, member B
chr3_+_63638343 8.507 NM_001080537
SNTN
sentan, cilia apical structure protein
chrX_+_106449861 7.715 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr19_+_4640028 7.336 NM_001167942
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr5_-_35938736 6.940 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr19_+_4639526 6.918 NM_152362
TNFAIP8L1
tumor necrosis factor, alpha-induced protein 8-like 1
chr1_+_111889194 6.741 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr21_-_43916298 6.632 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr1_+_228870801 5.955 NM_021205
RHOU
ras homolog gene family, member U
chr3_+_42947401 5.477 NM_207404
ZNF662
zinc finger protein 662
chr8_+_17354562 5.300 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr6_+_116937641 5.218 NM_001010892
NM_001161664
RSPH4A

radial spoke head 4 homolog A (Chlamydomonas)

chr6_-_32497925 4.920 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr20_+_9049660 4.803 NM_001172646
PLCB4
phospholipase C, beta 4
chr3_+_42947649 4.795 NM_001134656
ZNF662
zinc finger protein 662
chr4_-_7044664 4.692 NM_153376
CCDC96
coiled-coil domain containing 96
chr20_+_51588945 4.581 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr20_+_9288446 4.522 NM_000933
PLCB4
phospholipase C, beta 4
chr3_-_9994057 4.521 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr6_+_151815174 4.386 NM_025059
C6orf97
chromosome 6 open reading frame 97
chr1_-_150738292 4.379 NM_001199739
NM_004079
CTSS

cathepsin S

chr6_+_150690027 4.373 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr15_-_49255640 4.337 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr6_-_109762373 4.316 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr20_+_51801821 4.298 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr8_+_17396285 4.245 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr7_+_102073953 4.241 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr20_+_9198036 4.229 NM_182797
PLCB4
phospholipase C, beta 4
chr15_+_40697685 4.163 NM_001159508
NM_002225
IVD

isovaleryl-CoA dehydrogenase

chr6_+_112408673 4.008 NM_001033564
C6orf225
chromosome 6 open reading frame 225
chr16_-_46782104 3.942 NM_182493
MYLK3
myosin light chain kinase 3
chr11_+_101785720 3.927 NM_020802
KIAA1377
KIAA1377
chr2_+_106682111 3.854 NM_032411
C2orf40
chromosome 2 open reading frame 40
chr7_-_25164902 3.786 NM_018947
CYCS
cytochrome c, somatic
chr7_-_99573637 3.766 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr15_+_81426605 3.762 NM_173528
C15orf26
chromosome 15 open reading frame 26
chr4_+_15471488 3.698 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chrX_-_44202834 3.694 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chr1_-_117753476 3.593 NM_001253850
NM_024626
VTCN1

V-set domain containing T cell activation inhibitor 1

chr12_-_89918531 3.561 NM_003774
GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
chr17_+_72732958 3.546 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr17_+_72733350 3.540 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr14_+_74486049 3.537 NM_025057
C14orf45
chromosome 14 open reading frame 45
chr6_-_154677868 3.493 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr16_+_19467771 3.476 NM_024780
TMC5
transmembrane channel-like 5
chr11_+_62104773 3.425 NM_001083926
NM_025080
ASRGL1

asparaginase like 1

chr7_-_131241321 3.390 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr10_-_25304865 3.385 NM_145010
ENKUR
enkurin, TRPC channel interacting protein
chr16_+_58283819 3.360 NM_001142302
NM_014157
CCDC113

coiled-coil domain containing 113

chr14_-_95786095 3.340 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr16_-_54320367 3.336 NM_024336
IRX3
iroquois homeobox 3
chr9_-_117156684 3.317 NM_030767
AKNA
AT-hook transcription factor
chr6_-_154651214 3.250 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr1_-_160001723 3.217 NM_145167
PIGM
phosphatidylinositol glycan anchor biosynthesis, class M
chr4_+_75858205 3.207 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr2_-_68384575 3.146 NM_138458
WDR92
WD repeat domain 92
chr11_-_74178593 3.031 NM_005472
KCNE3
potassium voltage-gated channel, Isk-related family, member 3
chr5_+_42423811 3.028 NM_000163
GHR
growth hormone receptor
chr17_+_72667255 2.956 NM_175738
RAB37
RAB37, member RAS oncogene family
chr6_+_24495166 2.910 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr4_+_36283243 2.895 NM_001136536
DTHD1
death domain containing 1
chr5_+_42424553 2.883 NM_001242399
NM_001242400
GHR

growth hormone receptor

chr2_+_102770401 2.804 NM_000877
IL1R1
interleukin 1 receptor, type I
chr3_+_97483563 2.798 NM_032146
NM_177976
ARL6

ADP-ribosylation factor-like 6

chr16_+_19422056 2.790 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr5_+_42425093 2.783 NM_001242401
GHR
growth hormone receptor
chr3_-_121740968 2.775 NM_001199799
NM_001199800
NM_175924
ILDR1


immunoglobulin-like domain containing receptor 1


chr2_-_62081049 2.766 NM_001201543
NM_032180
FAM161A

family with sequence similarity 161, member A

chr5_+_42548144 2.756 NM_001242402
GHR
growth hormone receptor
chr5_+_42548314 2.680 NM_001242403
GHR
growth hormone receptor
chr5_+_42565963 2.669 NM_001242460
NM_001242461
NM_001242462
GHR


growth hormone receptor


chr5_-_16509106 2.634 NM_019000
FAM134B
family with sequence similarity 134, member B
chr5_-_68616299 2.627 NM_176816
CCDC125
coiled-coil domain containing 125
chr16_+_5008317 2.617 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr17_-_47439326 2.605 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr3_-_141944441 2.602 NM_001039547
GK5
glycerol kinase 5 (putative)
chr8_+_94767071 2.588 NM_001142301
NM_153704
TMEM67

transmembrane protein 67

chr5_+_149340287 2.588 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr6_+_143999058 2.584 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr5_+_42565562 2.563 NM_001242406
GHR
growth hormone receptor
chr15_+_78558522 2.558 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr5_+_42550181 2.550 NM_001242405
GHR
growth hormone receptor
chr15_+_78556901 2.543 NM_001130182
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_12629147 2.497 NM_033128
SCIN
scinderin
chr6_+_143929316 2.481 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr2_-_86564632 2.450 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr9_+_74729510 2.440 NM_001242507
GDA
guanine deaminase
chr2_-_62733475 2.422 NM_198276
TMEM17
transmembrane protein 17
chr5_+_42549657 2.417 NM_001242404
GHR
growth hormone receptor
chr6_-_90121966 2.411 NM_021244
RRAGD
Ras-related GTP binding D
chr13_-_37494370 2.401 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr15_+_78556485 2.390 NM_018602
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr17_+_6659155 2.363 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr4_+_55523906 2.318 NM_000222
NM_001093772
KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

chr3_-_45883562 2.304 NM_020347
LZTFL1
leucine zipper transcription factor-like 1
chr2_-_216946463 2.300 NM_018441
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr3_-_183273407 2.292 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr14_+_74111577 2.264 NM_001201366
NM_031427
DNAL1

dynein, axonemal, light chain 1

chr4_+_36285643 2.262 NM_001170700
DTHD1
death domain containing 1
chr2_-_86565205 2.252 NM_001164730
REEP1
receptor accessory protein 1
chr11_+_101918168 2.250 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr4_-_186300151 2.247 NM_018409
LRP2BP
LRP2 binding protein
chr17_-_61518174 2.228 NM_001017917
CYB561
cytochrome b-561
chr21_-_47743753 2.195 NM_058180
C21orf58
chromosome 21 open reading frame 58
chr11_+_111848008 2.193 NM_033425
DIXDC1
DIX domain containing 1
chr19_-_23578226 2.131 NM_003430
ZNF91
zinc finger protein 91
chr5_-_150603649 2.127 NM_015621
CCDC69
coiled-coil domain containing 69
chr16_+_3559893 2.088 NM_024793
CLUAP1
clusterin associated protein 1
chr3_+_49449638 2.085 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr4_+_184826427 2.066 NM_020225
STOX2
storkhead box 2
chr5_-_16617085 2.049 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr15_+_45315301 2.023 NM_003104
SORD
sorbitol dehydrogenase
chr19_+_7069454 2.013 NM_001044387
NM_001044388
NM_024341
ZNF557


zinc finger protein 557


chr8_+_17780351 2.012 NM_006197
PCM1
pericentriolar material 1
chr7_-_150721551 2.006 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr19_-_20748540 1.986 NM_001159293
ZNF737
zinc finger protein 737
chr3_+_99357439 1.985 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr3_-_148939784 1.985 NM_000096
CP
ceruloplasmin (ferroxidase)
chr16_-_12897693 1.981 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr4_+_74702272 1.949 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr14_+_56584854 1.941 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr2_+_61292999 1.925 NM_001129993
KIAA1841
KIAA1841
chr6_-_97345760 1.907 NM_014165
NDUFAF4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr8_+_76452202 1.896 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr4_+_37455551 1.891 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chr1_+_25943958 1.871 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr5_+_130506635 1.864 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr13_-_52585472 1.855 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr7_+_12610202 1.854 NM_001112706
SCIN
scinderin
chr11_-_26593667 1.854 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr2_-_148779172 1.843 NM_181742
ORC4
origin recognition complex, subunit 4
chr5_-_131826426 1.836 NM_002198
IRF1
interferon regulatory factor 1
chr7_-_100964923 1.832 NM_001130820
NM_001130821
NM_001130822
NM_022777
RABL5



RAB, member RAS oncogene family-like 5



chr2_+_86333304 1.822 NM_017952
PTCD3
Pentatricopeptide repeat domain 3
chr11_+_46299161 1.817 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr4_-_88141614 1.806 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr11_-_74109417 1.795 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr3_+_179370779 1.793 NM_003940
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr14_+_73525187 1.790 NM_021239
RBM25
RNA binding motif protein 25
chr4_+_37585854 1.789 NM_018302
C4orf19
chromosome 4 open reading frame 19
chr3_-_132378492 1.772 NM_032169
ACAD11
acyl-CoA dehydrogenase family, member 11
chr17_-_61523544 1.762 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr6_+_117002349 1.754 NM_002269
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr1_+_212738675 1.716 NM_001030287
ATF3
activating transcription factor 3
chr9_-_215892 1.708 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr3_+_171561138 1.703 NM_001164436
TMEM212
transmembrane protein 212
chr11_-_93276513 1.696 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr6_+_18155535 1.696 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr9_-_124984018 1.692 NM_001242335
LHX6
LIM homeobox 6
chr9_-_124990949 1.690 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr19_+_16999807 1.689 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_-_75657153 1.678 NM_012091
ADAT1
adenosine deaminase, tRNA-specific 1
chr3_+_119421865 1.655 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr10_-_116418056 1.655 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_-_116444374 1.624 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chrX_+_16964730 1.623 NM_001080975
NM_004726
REPS2

RALBP1 associated Eps domain containing 2

chr8_+_110551916 1.612 NM_198120
EBAG9
estrogen receptor binding site associated, antigen, 9
chr5_-_121412805 1.607 NM_001178102
LOX
lysyl oxidase
chr5_+_167718485 1.603 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr17_-_33775761 1.601 NM_144682
SLFN13
schlafen family member 13
chr1_+_89990396 1.595 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr15_-_40398286 1.595 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr2_-_152118258 1.590 NM_198557
RBM43
RNA binding motif protein 43
chr1_+_60280462 1.588 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr3_-_196439067 1.588 NM_032898
CEP19
centrosomal protein 19kDa
chr15_-_40398573 1.581 NM_033503
BMF
Bcl2 modifying factor
chr3_-_93782066 1.578 NM_001195643
DHFRL1
dihydrofolate reductase-like 1
chr5_-_121414011 1.574 NM_002317
LOX
lysyl oxidase
chr5_-_55290601 1.568 NM_001190981
NM_002184
NM_175767
IL6ST


interleukin 6 signal transducer (gp130, oncostatin M receptor)


chr20_-_18447622 1.567 NM_001099407
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr10_+_120789227 1.563 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr8_+_110552309 1.545 NM_004215
EBAG9
estrogen receptor binding site associated, antigen, 9
chr7_+_94138991 1.544 NM_022900
CASD1
CAS1 domain containing 1
chr12_-_89920038 1.543 NM_001199781
NM_001199782
NM_172240
POC1B-GALNT4

POC1B
POC1B-GALNT4 readthrough

POC1 centriolar protein homolog B (Chlamydomonas)
chr1_+_38261079 1.542 NM_152496
MANEAL
mannosidase, endo-alpha-like
chr3_+_121613170 1.540 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr9_+_74764266 1.536 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr4_+_106067031 1.535 NM_017628
TET2
tet methylcytosine dioxygenase 2
chr10_-_62703822 1.533 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr1_+_212781969 1.531 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr9_-_124990706 1.530 NM_001242333
LHX6
LIM homeobox 6
chr2_+_183943286 1.521 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr10_-_116286661 1.518 NM_006720
ABLIM1
actin binding LIM protein 1
chr2_-_175351755 1.507 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chr19_+_57702833 1.506 NM_003417
ZNF264
zinc finger protein 264
chr20_-_32307889 1.502 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr16_+_78056411 1.500 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr3_-_93781659 1.498 NM_176815
DHFRL1
dihydrofolate reductase-like 1
chr2_-_24149899 1.492 NM_001242338
NM_017552
ATAD2B

ATPase family, AAA domain containing 2B

chr19_-_44143943 1.479 NM_145296
CADM4
cell adhesion molecule 4
chr17_-_1733083 1.472 NM_052928
SMYD4
SET and MYND domain containing 4
chr10_-_94050799 1.467 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_+_38259458 1.467 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr3_-_121553907 1.463 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr7_+_3340919 1.456 NM_152744
SDK1
sidekick cell adhesion molecule 1
chr2_-_95825262 1.452 NM_032788
ZNF514
zinc finger protein 514
chr8_+_28351694 1.450 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chrX_+_12885190 1.442 NM_016562
TLR7
toll-like receptor 7
chr2_-_148778262 1.442 NM_001190882
NM_001190879
NM_002552
NM_001190881
NM_181741
ORC4




origin recognition complex, subunit 4




chr8_+_79578258 1.440 NM_016010
FAM164A
family with sequence similarity 164, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.36 1.06e-03 GO:0010468 regulation of gene expression
1.39 2.70e-03 GO:0006355 regulation of transcription, DNA-dependent
1.38 2.99e-03 GO:0051252 regulation of RNA metabolic process
1.34 1.09e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 1.28e-02 GO:0044260 cellular macromolecule metabolic process
1.27 1.57e-02 GO:0060255 regulation of macromolecule metabolic process
1.32 2.97e-02 GO:0010556 regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 5.61e-06 GO:0043231 intracellular membrane-bounded organelle
1.16 6.99e-06 GO:0043227 membrane-bounded organelle
1.11 1.72e-05 GO:0044424 intracellular part
1.11 2.23e-05 GO:0005622 intracellular
1.13 1.40e-04 GO:0043229 intracellular organelle
1.13 1.98e-04 GO:0043226 organelle
1.20 5.92e-04 GO:0005634 nucleus
1.05 7.27e-03 GO:0044464 cell part
1.05 7.46e-03 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.60 2.05e-10 GO:0008270 zinc ion binding
1.54 6.60e-10 GO:0046914 transition metal ion binding
1.37 5.67e-09 GO:0046872 metal ion binding
1.36 1.61e-08 GO:0043169 cation binding
1.36 2.23e-08 GO:0043167 ion binding
1.29 9.66e-04 GO:0003676 nucleic acid binding
1.32 8.10e-03 GO:0003677 DNA binding