Motif ID: VSX1,2.p2

Z-value: 0.488


Transcription factors associated with VSX1,2.p2:

Gene SymbolEntrez IDGene Name
VSX1 30813 visual system homeobox 1
VSX2 338917 visual system homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
VSX1chr20_-_250627560.048.2e-01Click!


Activity profile for motif VSX1,2.p2.

activity profile for motif VSX1,2.p2


Sorted Z-values histogram for motif VSX1,2.p2

Sorted Z-values for motif VSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of VSX1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_37723378 1.968


chr6_+_130339715 1.185 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chrX_+_43515441 1.029 MAOA
monoamine oxidase A
chr12_+_15699277 0.992 NM_030668
NM_030669
NM_030670
NM_030671
PTPRO



protein tyrosine phosphatase, receptor type, O



chrX_+_43515406 0.865 NM_000240
MAOA
monoamine oxidase A
chr3_+_121774208 0.863 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr16_+_55515468 0.726 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr6_+_64231626 0.498 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_-_190927321 0.444 NM_005259
MSTN
myostatin
chr1_+_179560747 0.430 NM_001199091
NM_001199085
NM_173533
TDRD5


tudor domain containing 5


chr4_-_138453628 0.422 NM_019035
PCDH18
protocadherin 18
chrX_+_43515531 0.415 MAOA
monoamine oxidase A
chr12_+_105153258 0.391 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr11_-_57417247 0.367 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr1_-_152386727 0.342 NM_016190
CRNN
cornulin
chrX_+_7137471 0.341 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr5_+_126984712 0.332 NM_001048252
CTXN3
cortexin 3
chr1_-_205325915 0.321 NM_018203
KLHDC8A
kelch domain containing 8A
chr13_-_34250899 0.320 NM_001243476
STARD13
StAR-related lipid transfer (START) domain containing 13
chrX_+_107288199 0.317 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr4_+_78432905 0.317 NM_006419
CXCL13
chemokine (C-X-C motif) ligand 13
chr4_+_5526882 0.310 NM_005750
C4orf6
chromosome 4 open reading frame 6
chr4_+_169418167 0.294 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr8_+_22210311 0.280 PIWIL2
piwi-like 2 (Drosophila)
chr12_-_91505215 0.277 LUM
lumican
chr11_-_118135197 0.276 NM_005797
NM_144765
MPZL2

myelin protein zero-like 2

chr13_-_36050758 0.275 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr21_-_35899046 0.273 NM_203418
RCAN1
regulator of calcineurin 1
chr8_-_10512616 0.262 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr4_+_70796798 0.259 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr3_+_188664939 0.256 TPRG1
tumor protein p63 regulated 1
chr1_+_111770280 0.250 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr8_+_54764367 0.246 NM_170587
RGS20
regulator of G-protein signaling 20
chr12_-_4488707 0.234 NM_020638
FGF23
fibroblast growth factor 23
chr1_+_151735444 0.209 NM_001134939
OAZ3
ornithine decarboxylase antizyme 3
chr7_-_83824216 0.205 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_164796275 0.198 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr3_-_108248168 0.196 NM_014981
MYH15
myosin, heavy chain 15
chr5_-_39394423 0.188 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_+_127898318 0.176 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr4_-_89978117 0.176 NM_014883
FAM13A
family with sequence similarity 13, member A
chr4_-_69111333 0.173 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr4_-_123377471 0.166 NM_000586
IL2
interleukin 2
chr16_+_49407807 0.161 NM_144602
C16orf78
chromosome 16 open reading frame 78
chr15_-_55563091 0.161 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr1_+_28585959 0.161 NM_031459
SESN2
sestrin 2
chr11_+_55578842 0.152 NM_001004738
OR5L1
olfactory receptor, family 5, subfamily L, member 1
chr4_-_39979159 0.152 PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr2_-_80531716 0.150 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr3_-_101039403 0.149 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr10_-_92681025 0.145 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_+_132897342 0.144 GPR107
G protein-coupled receptor 107
chr9_+_116356199 0.142 NM_144489
RGS3
regulator of G-protein signaling 3
chr11_-_71752099 0.142 NUMA1
nuclear mitotic apparatus protein 1
chr6_+_155585146 0.142 NM_001001346
CLDN20
claudin 20
chr10_+_18689512 0.136 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr7_-_99774821 0.135 NM_152742
GPC2
glypican 2
chr10_-_56560947 0.135 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr5_+_175108463 0.132 NM_022304
HRH2
histamine receptor H2
chr9_+_12774988 0.132 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr14_+_32798478 0.131 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr19_-_7698569 0.131 NM_174895
PCP2
Purkinje cell protein 2
chr16_-_67977956 0.130 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr8_+_9413390 0.129 TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr16_+_6823809 0.125 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_52604488 0.123 NM_001242696
LOC283403
uncharacterized LOC283403
chr4_-_39979549 0.121 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr2_-_80530943 0.118 LRRTM1
leucine rich repeat transmembrane neuronal 1
chr6_+_155538096 0.117 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_+_129008044 0.115 AHCYL2
adenosylhomocysteinase-like 2
chr1_-_186417855 0.112 NM_022576
PDC
phosducin
chr11_-_5323174 0.112 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr11_-_124190092 0.110 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr6_+_121756744 0.109 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr8_-_52721903 0.106 NM_144651
PXDNL
peroxidasin homolog (Drosophila)-like
chr17_-_39150384 0.102 NM_033185
KRTAP3-3
keratin associated protein 3-3
chr7_+_141811508 0.100 LOC93432
maltase-glucoamylase (alpha-glucosidase) pseudogene
chr10_+_83637442 0.095 NM_001165973
NRG3
neuregulin 3
chr7_+_102023016 0.093


chr6_+_29079586 0.089 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr11_-_118134956 0.087 MPZL2
myelin protein zero-like 2
chr7_-_88425030 0.086 NM_152706
C7orf62
chromosome 7 open reading frame 62
chr16_+_12058963 0.085 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr12_-_53012332 0.075 NM_175068
KRT73
keratin 73
chr10_+_32856650 0.074 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr12_-_52828105 0.074 NM_004693
KRT75
keratin 75
chr10_-_33224485 0.073 NM_033668
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr4_-_122137781 0.070 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr9_+_21440452 0.069 NM_024013
IFNA1
interferon, alpha 1
chr7_-_87342569 0.066 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr6_+_28317687 0.064 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr1_+_117544371 0.064 NM_004258
CD101
CD101 molecule
chr11_+_60163486 0.064 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr15_-_55562483 0.063 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr6_-_111888520 0.062 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr1_+_28764660 0.061 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr9_-_21202201 0.061 NM_021057
IFNA7
interferon, alpha 7
chr15_-_42448769 0.060 NM_213600
PLA2G4F
phospholipase A2, group IVF
chrX_-_21676416 0.060 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr6_+_160542862 0.058 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr11_+_87032428 0.058 TMEM135
transmembrane protein 135
chr1_+_198608216 0.058 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_52946734 0.057 NM_033448
KRT71
keratin 71
chr11_-_118134986 0.056 MPZL2
myelin protein zero-like 2
chr11_-_16497917 0.056 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr16_+_31271311 0.055 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chrX_-_138790328 0.054 NM_001099855
NM_001171876
MCF2

MCF.2 cell line derived transforming sequence

chr8_-_17743062 0.053 FGL1
fibrinogen-like 1
chr11_+_89764273 0.052 NM_001195234
TRIM49L2
tripartite motif containing 49-like 2
chr11_+_59824054 0.052 NM_001031666
NM_001031809
NM_006138
MS4A3


membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)


chr14_+_67831484 0.052 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr7_+_50348255 0.051 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr4_+_115543522 0.050 NM_003360
UGT8
UDP glycosyltransferase 8
chr1_+_3668961 0.049 NM_152492
CCDC27
coiled-coil domain containing 27
chr11_-_114466471 0.049 NM_001077639
NM_017678
FAM55D

family with sequence similarity 55, member D

chr6_+_49467670 0.048 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr5_-_9630462 0.048 NM_019599
TAS2R1
taste receptor, type 2, member 1
chrX_+_79675945 0.048 NM_152630
FAM46D
family with sequence similarity 46, member D
chr16_-_20338808 0.048 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr11_-_89541742 0.047 NM_020358
TRIM49
tripartite motif containing 49
chr18_+_61554938 0.047 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chrX_-_151619669 0.047 NM_000808
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr1_-_157746863 0.045 NM_030764
FCRL2
Fc receptor-like 2
chr8_+_92261515 0.044 NM_052832
NM_134266
SLC26A7

solute carrier family 26, member 7

chr12_+_18414473 0.043 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr10_+_95372344 0.043 NM_006204
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr2_-_99871569 0.042 NM_175735
LYG2
lysozyme G-like 2
chr11_+_17741109 0.041 NM_002478
MYOD1
myogenic differentiation 1
chr14_-_106573348 0.041 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr7_-_44580857 0.040 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr19_+_4769144 0.040 MIR7-3HG
MIR7-3 host gene (non-protein coding)
chr1_-_173174611 0.040 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr8_-_62602285 0.039 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr1_-_200377262 0.039 ZNF281
zinc finger protein 281
chr10_-_50396380 0.039 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr2_-_80531486 0.038 NM_178839
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr3_-_157221362 0.037 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr4_-_138453564 0.035 PCDH18
protocadherin 18
chr8_-_86290333 0.034 NM_001128829
NM_001128830
NM_001128831
NM_001738
CA1



carbonic anhydrase I



chr4_+_88571453 0.033 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr10_+_5136613 0.033 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_+_159557649 0.032 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr18_+_3447607 0.032 NM_173207
TGIF1
TGFB-induced factor homeobox 1
chr10_-_69455926 0.029 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr14_+_61201450 0.028 NM_001177963
NM_002431
MNAT1

menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)

chr17_-_29624249 0.027 NM_002544
OMG
oligodendrocyte myelin glycoprotein
chr8_-_87755880 0.026 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr11_+_59824129 0.025 MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr3_-_126327397 0.022 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr8_+_19796581 0.022 NM_000237
LPL
lipoprotein lipase
chr13_+_111839172 0.021 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_115342302 0.021 GAP43
growth associated protein 43
chr22_+_23154240 0.019


chr18_-_51690988 0.019 MBD2
methyl-CpG binding domain protein 2
chr6_+_161123224 0.019 NM_000301
NM_001168338
PLG

plasminogen

chr12_-_56106061 0.019 NM_001144997
ITGA7
integrin, alpha 7
chr12_-_53730003 0.019 NM_001173467
SP7
Sp7 transcription factor
chr3_-_157213138 0.018 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr12_+_10460416 0.018 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr11_+_65984213 0.017 PACS1
phosphofurin acidic cluster sorting protein 1
chr3_-_167191808 0.017 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr7_-_135613197 0.015 LUZP6
leucine zipper protein 6
chr2_+_29038862 0.015 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr2_+_202671197 0.014 NM_139158
CDK15
cyclin-dependent kinase 15
chr2_+_189839132 0.014 COL3A1
collagen, type III, alpha 1
chr7_-_81399286 0.013 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr11_+_45115563 0.013 NM_020229
PRDM11
PR domain containing 11
chr1_-_68697997 0.013 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr12_-_71031174 0.012 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr14_+_102276279 0.011 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr12_-_54653369 0.011 NM_001127321
CBX5
chromobox homolog 5
chr12_+_93096618 0.011 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr2_-_65159566 0.011 LOC400958
uncharacterized LOC400958
chr1_+_81771844 0.010 LPHN2
latrophilin 2
chrX_-_24690740 0.010 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr10_-_52645430 0.009 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr9_+_66457288 0.008


chr4_+_74301932 0.007 NM_001134
AFP
alpha-fetoprotein
chr12_-_57328044 0.007 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr20_-_52199635 0.007 NM_006526
ZNF217
zinc finger protein 217
chr1_-_155649597 0.006 NM_001198899
YY1AP1
YY1 associated protein 1
chr17_+_39261640 0.006 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr12_-_58135853 0.004 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr3_+_151985828 0.003 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr19_-_47137938 0.003 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr2_-_219031646 0.002 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr6_+_105404922 0.001 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr2_+_109204745 0.001 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.06 8.57e-04 GO:0005615 extracellular space
18.05 1.08e-02 GO:0001750 photoreceptor outer segment
2.47 1.38e-02 GO:0044421 extracellular region part
1.94 1.97e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
13.54 5.13e-03 GO:0003823 antigen binding