Motif ID: XBP1.p3

Z-value: 0.944


Transcription factors associated with XBP1.p3:

Gene SymbolEntrez IDGene Name
XBP1 7494 X-box binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
XBP1chr22_-_29196537-0.183.5e-01Click!


Activity profile for motif XBP1.p3.

activity profile for motif XBP1.p3


Sorted Z-values histogram for motif XBP1.p3

Sorted Z-values for motif XBP1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of XBP1.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_207324 2.268 BET1L
blocked early in transport 1 homolog (S. cerevisiae)-like
chr20_+_25228698 1.796 NM_002862
 PYGB
phosphorylase, glycogen; brain
chr12_-_99038705 1.773 IKBIP
IKBKB interacting protein
chr16_-_75529278 1.246


chr20_+_44044706 1.242 NM_001184728
NM_001184729
NM_001184730
NM_015937
 PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr15_-_83953465 1.149 NM_001717
 BNC1
basonuclin 1
chr17_+_15848230 1.141 NM_000676
 ADORA2B
adenosine A2b receptor
chr12_-_99038401 1.132 NM_153687
NM_201612
NM_201613
 IKBIP


IKBKB interacting protein


chr3_-_52090090 1.115 NM_001947
 DUSP7
dual specificity phosphatase 7
chr7_-_128045995 1.109 NM_001142573
NM_001142574
NM_001142575
 IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr2_+_173420794 1.062 PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr2_-_220408264 1.045 NM_024536
 CHPF
chondroitin polymerizing factor
chr14_-_23834417 0.986 EFS
embryonal Fyn-associated substrate
chr22_+_38864015 0.952 NM_006855
NM_016657
 KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr7_-_30066124 0.944 NM_017946
 FKBP14
FK506 binding protein 14, 22 kDa
chr1_-_38100287 0.919 RSPO1
R-spondin 1
chr2_+_173420873 0.900 PDK1
pyruvate dehydrogenase kinase, isozyme 1
chr3_+_171758289 0.899 NM_001135095
 FNDC3B
fibronectin type III domain containing 3B
chr6_+_41606193 0.841 NM_005586
 MDFI
MyoD family inhibitor
chr2_+_173420776 0.835 NM_002610
 PDK1
pyruvate dehydrogenase kinase, isozyme 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 54 entries
enrichment   p-value GO term description
27.53 2.13e-05 GO:0048207 vesicle targeting, rough ER to cis-Golgi
27.53 2.13e-05 GO:0048208 COPII vesicle coating
27.53 2.13e-05 GO:0090114 COPII-coated vesicle budding
22.94 1.31e-03 GO:0048194 Golgi vesicle budding
22.94 1.31e-03 GO:0048200 Golgi transport vesicle coating
22.94 1.31e-03 GO:0048205 COPI coating of Golgi vesicle
22.71 2.84e-10 GO:0048199 vesicle targeting, to, from or within Golgi
20.65 3.03e-02 GO:0045047 protein targeting to ER
20.65 3.03e-02 GO:0072599 establishment of protein localization in endoplasmic reticulum
18.93 3.87e-09 GO:0006901 vesicle coating
18.17 6.77e-09 GO:0006900 membrane budding
15.14 7.43e-08 GO:0006903 vesicle targeting
14.57 2.66e-03 GO:0070972 protein localization in endoplasmic reticulum
11.80 1.07e-02 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER
10.82 4.48e-06 GO:0051650 establishment of vesicle localization
9.53 4.07e-04 GO:0006888 ER to Golgi vesicle-mediated transport
8.57 6.28e-05 GO:0051648 vesicle localization
8.26 6.00e-06 GO:0016050 vesicle organization
7.68 3.03e-07 GO:0018196 peptidyl-asparagine modification
7.68 3.03e-07 GO:0018279 protein N-linked glycosylation via asparagine

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
25.81 1.10e-04 GO:0030127 COPII vesicle coat
17.70 1.27e-04 GO:0030663 COPI coated vesicle membrane
16.52 1.62e-02 GO:0008250 oligosaccharyltransferase complex
15.49 3.26e-04 GO:0012507 ER to Golgi transport vesicle membrane
14.57 4.94e-04 GO:0030137 COPI-coated vesicle
13.77 3.68e-02 GO:0030126 COPI vesicle coat
13.04 1.04e-03 GO:0030134 ER to Golgi transport vesicle
10.59 5.47e-06 GO:0030120 vesicle coat
8.14 1.36e-06 GO:0030117 membrane coat
8.14 1.36e-06 GO:0048475 coated membrane
7.79 1.24e-04 GO:0005793 ER-Golgi intermediate compartment
7.74 2.65e-02 GO:0030660 Golgi-associated vesicle membrane
6.68 4.93e-07 GO:0005788 endoplasmic reticulum lumen
5.78 4.86e-02 GO:0030658 transport vesicle membrane
5.39 3.08e-05 GO:0030662 coated vesicle membrane
3.68 2.18e-05 GO:0030659 cytoplasmic vesicle membrane
3.56 4.06e-05 GO:0012506 vesicle membrane
3.36 6.58e-03 GO:0030135 coated vesicle
3.13 2.23e-11 GO:0044432 endoplasmic reticulum part
3.06 5.87e-04 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
18.35 1.21e-02 GO:0003756 protein disulfide isomerase activity
18.35 1.21e-02 GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups
18.35 1.21e-02 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds
10.32 1.11e-03 GO:0015035 protein disulfide oxidoreductase activity
9.33 2.32e-03 GO:0015036 disulfide oxidoreductase activity
6.48 8.89e-03 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors
4.86 1.22e-02 GO:0008565 protein transporter activity
1.25 7.85e-03 GO:0005515 protein binding