Motif ID: ZEB1.p2

Z-value: 1.097


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZEB1chr10_+_316074190.105.9e-01Click!


Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_97401588 4.199 FBP1
fructose-1,6-bisphosphatase 1
chr9_-_97401746 3.063 FBP1
fructose-1,6-bisphosphatase 1
chr9_-_97401833 2.565 NM_000507
 FBP1
fructose-1,6-bisphosphatase 1
chr11_-_2018568 1.887 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chrX_-_152939256 1.849 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr11_-_2018703 1.842 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr2_-_165477818 1.823 GRB14
growth factor receptor-bound protein 14
chr2_-_165477986 1.785 GRB14
growth factor receptor-bound protein 14
chr11_-_2019070 1.578 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr19_+_917285 1.476 NM_032551
 KISS1R
KISS1 receptor
chr17_+_40811261 1.367 NM_016437
 TUBG2
tubulin, gamma 2
chr17_-_43510279 1.326 NM_174919
 ARHGAP27
Rho GTPase activating protein 27
chrX_-_152938742 1.323 NM_001135740
 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr18_+_77623667 1.312 NM_012283
 KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr9_+_17578952 1.302 NM_003026
 SH3GL2
SH3-domain GRB2-like 2
chr1_+_65991390 1.250 LEPR
leptin receptor
chr7_+_26331493 1.226 NM_001199835
NM_013322
 SNX10

sorting nexin 10

chr12_+_6420098 1.193 NM_001144856
 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr9_+_139839697 1.146 NM_000606
 C8G
complement component 8, gamma polypeptide
chr11_-_2018446 1.136 H19
H19, imprinted maternally expressed transcript (non-protein coding)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.85 3.80e-02 GO:0034330 cell junction organization
1.36 4.63e-02 GO:0006468 protein phosphorylation
1.30 3.20e-03 GO:0035556 intracellular signal transduction
1.27 1.58e-02 GO:0009966 regulation of signal transduction
1.26 6.49e-03 GO:0023051 regulation of signaling
1.22 1.39e-02 GO:0048523 negative regulation of cellular process
1.17 4.34e-03 GO:0007165 signal transduction
1.17 1.77e-02 GO:0048856 anatomical structure development
1.16 2.80e-03 GO:0051716 cellular response to stimulus
1.15 2.35e-02 GO:0023052 signaling
1.11 6.09e-04 GO:0050794 regulation of cellular process
1.10 3.64e-03 GO:0065007 biological regulation
1.10 3.85e-03 GO:0050789 regulation of biological process
1.08 1.63e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.69 3.94e-02 GO:0042641 actomyosin
1.82 5.95e-03 GO:0005912 adherens junction
1.78 4.81e-02 GO:0005938 cell cortex
1.75 1.24e-02 GO:0070161 anchoring junction
1.67 1.67e-02 GO:0005911 cell-cell junction
1.40 6.67e-03 GO:0030054 cell junction
1.39 3.71e-03 GO:0015630 microtubule cytoskeleton
1.33 6.67e-04 GO:0044430 cytoskeletal part
1.29 7.90e-05 GO:0005856 cytoskeleton
1.25 6.19e-05 GO:0005829 cytosol
1.16 2.19e-16 GO:0005737 cytoplasm
1.14 4.15e-06 GO:0044444 cytoplasmic part
1.09 6.29e-10 GO:0005622 intracellular
1.08 1.20e-08 GO:0044424 intracellular part
1.06 3.80e-02 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.01 3.20e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
1.54 1.70e-02 GO:0003779 actin binding
1.54 4.01e-02 GO:0005083 small GTPase regulator activity
1.46 1.96e-02 GO:0004674 protein serine/threonine kinase activity
1.45 1.49e-02 GO:0030695 GTPase regulator activity
1.44 2.01e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.39 4.40e-02 GO:0008092 cytoskeletal protein binding
1.37 4.27e-02 GO:0005198 structural molecule activity
1.35 1.16e-02 GO:0016301 kinase activity
1.32 5.68e-03 GO:0030234 enzyme regulator activity
1.32 8.90e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.16 1.12e-11 GO:0005515 protein binding
1.06 2.31e-04 GO:0005488 binding