Motif ID: ZFP161.p2

Z-value: 1.058


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZFP161chr18_-_52960130.301.1e-01Click!


Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_71814948 3.166 NM_152676
NM_001142958
FBXO15

F-box protein 15

chr10_+_82116557 2.859 NM_032372
DYDC2
DPY30 domain containing 2
chr17_+_36861398 2.562 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr10_+_70587562 2.383 NM_001130162
STOX1
storkhead box 1
chr10_+_70587293 2.101 NM_001130159
NM_001130160
NM_001130161
NM_152709
STOX1



storkhead box 1



chr22_-_31741761 1.953 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr2_-_28113211 1.815 NM_022128
RBKS
ribokinase
chr11_-_33890931 1.702 LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_-_45935627 1.700 ZBTB7C
zinc finger and BTB domain containing 7C
chr1_-_223537400 1.661 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr7_+_139877154 1.617 LOC100134229
uncharacterized LOC100134229
chr11_+_61276271 1.599 NM_001145077
LRRC10B
leucine rich repeat containing 10B
chr17_+_260092 1.591 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr14_+_75536298 1.570 NM_001042430
NM_024643
FAM164C

family with sequence similarity 164, member C

chr22_-_31742217 1.538 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr11_-_6440288 1.532 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr20_+_9049660 1.531 NM_001172646
PLCB4
phospholipase C, beta 4
chr10_-_82116499 1.510 NM_138812
DYDC1
DPY30 domain containing 1
chr11_-_6440631 1.497 NM_145689
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr7_-_73184535 1.470 NM_001306
CLDN3
claudin 3
chr16_-_1661969 1.454 NM_014714
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr9_+_71320105 1.451 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr2_-_99758034 1.434 NM_182911
TSGA10
testis specific, 10
chr16_-_54962707 1.400 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr11_+_71791376 1.397 NM_001145307
NM_001145308
NM_001205138
NM_145309
LRTOMT



leucine rich transmembrane and 0-methyltransferase domain containing



chr11_-_33891258 1.338 LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_-_6110561 1.293 NM_000635
NM_134433
RFX2

regulatory factor X, 2 (influences HLA class II expression)

chr4_+_41362750 1.290 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr15_+_75287829 1.269 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr15_-_50978726 1.259 TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr22_-_31742329 1.248 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr15_-_56757239 1.240 NM_018365
MNS1
meiosis-specific nuclear structural 1
chr12_-_112450914 1.217 NM_001193453
NM_001193531
NM_138341
LOC728543
TMEM116


uncharacterized LOC728543
transmembrane protein 116


chr17_-_57184116 1.203 TRIM37
tripartite motif containing 37
chr2_-_86564632 1.195 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr16_-_1968230 1.190 NM_001009606
HS3ST6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr19_-_5340700 1.185 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr5_+_76506705 1.183 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr1_+_210502639 1.143 NM_001170580
HHAT
hedgehog acyltransferase
chr5_+_75699003 1.132 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr22_+_39853316 1.118 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_210502188 1.112 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr16_-_755718 1.109 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr8_+_75896707 1.099 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr22_-_39548448 1.098 NM_175709
CBX7
chromobox homolog 7
chr19_-_6110491 1.075 RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr9_-_4300028 1.071 NM_001042413
GLIS3
GLIS family zinc finger 3
chr15_-_50978921 1.048 TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr2_-_239148545 1.039 HES6
hairy and enhancer of split 6 (Drosophila)
chr3_+_49449638 1.038 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr2_+_220094478 1.029 NM_018089
NM_001042410
ANKZF1

ankyrin repeat and zinc finger domain containing 1

chr6_+_84743250 1.026 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr16_-_28074776 1.015 NM_001109763
GSG1L
GSG1-like
chr6_+_146920135 1.008 NM_024694
C6orf103
chromosome 6 open reading frame 103
chr13_-_36705432 1.006 DCLK1
doublecortin-like kinase 1
chr19_+_1000295 1.006 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr22_-_31741565 0.996 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr3_-_53079959 0.995 SFMBT1
Scm-like with four mbt domains 1
chr14_-_92414004 0.995 NM_006329
FBLN5
fibulin 5
chr10_-_104179468 0.994 PSD
pleckstrin and Sec7 domain containing
chr3_-_133614421 0.987 NM_016577
RAB6B
RAB6B, member RAS oncogene family
chr3_+_14444083 0.961 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr7_+_158649200 0.955 NM_018051
WDR60
WD repeat domain 60
chr6_+_19837599 0.954 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr3_+_49449753 0.943 TCTA
T-cell leukemia translocation altered gene
chr1_+_111889194 0.925 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr1_+_183605207 0.923 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr6_+_126070724 0.906 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr11_-_46867788 0.906 CKAP5
cytoskeleton associated protein 5
chr9_-_126030854 0.895 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr12_+_112451261 0.891 ERP29
endoplasmic reticulum protein 29
chr5_-_179498598 0.881 RNF130
ring finger protein 130
chr3_-_9994057 0.880 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr10_+_95753684 0.879 NM_016341
PLCE1
phospholipase C, epsilon 1
chr11_-_33891361 0.877 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_112451151 0.870 NM_001034025
NM_006817
ERP29

endoplasmic reticulum protein 29

chr9_+_140135738 0.858 TUBB4B
tubulin, beta 4B class IVb
chr6_-_90121656 0.848 RRAGD
Ras-related GTP binding D
chr3_-_133614296 0.846 RAB6B
RAB6B, member RAS oncogene family
chr9_-_126030792 0.843 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr7_+_3340919 0.837 NM_152744
SDK1
sidekick cell adhesion molecule 1
chr6_+_18155535 0.831 NM_153042
KDM1B
lysine (K)-specific demethylase 1B
chr17_-_19281494 0.829 NM_001243475
B9D1
B9 protein domain 1
chr15_-_93616308 0.827 RGMA
RGM domain family, member A
chr9_+_140135742 0.827 TUBB4B
tubulin, beta 4B class IVb
chr12_+_50451486 0.826 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr14_+_105266878 0.825 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr6_+_109762043 0.808 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr2_-_213403280 0.805 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr5_-_179498995 0.796 NM_018434
RNF130
ring finger protein 130
chr2_-_233792825 0.786 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr12_+_52345437 0.782 NM_004302
NM_020328
ACVR1B

activin A receptor, type IB

chr4_+_75858205 0.771 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr1_+_205538111 0.768 NM_181644
MFSD4
major facilitator superfamily domain containing 4
chr9_+_137533713 0.766 COL5A1
collagen, type V, alpha 1
chrX_-_153714904 0.765 NM_014235
UBL4A
ubiquitin-like 4A
chr17_-_57184114 0.763 TRIM37
tripartite motif containing 37
chr9_+_124922189 0.756 NM_198469
MORN5
MORN repeat containing 5
chr4_+_186317964 0.753 ANKRD37
ankyrin repeat domain 37
chr1_-_217311095 0.752 NM_001134285
ESRRG
estrogen-related receptor gamma
chr6_+_135502445 0.750 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr6_-_109762373 0.743 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr1_+_4715104 0.740 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr6_+_135502477 0.735 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr9_-_136024522 0.734 NM_001042368
RALGDS
ral guanine nucleotide dissociation stimulator
chr14_-_92413738 0.731 FBLN5
fibulin 5
chr6_-_90121966 0.727 NM_021244
RRAGD
Ras-related GTP binding D
chr5_+_10441973 0.725 NM_001201466
NM_031916
ROPN1L

rhophilin associated tail protein 1-like

chr11_-_62494927 0.724 HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr8_+_17354562 0.709 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr15_+_59730272 0.699 NM_152450
FAM81A
family with sequence similarity 81, member A
chr11_-_2292181 0.695 NM_005170
ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr6_-_90121911 0.695 RRAGD
Ras-related GTP binding D
chr11_+_45907198 0.694 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr19_-_10764449 0.692 LOC147727
uncharacterized LOC147727
chr2_+_228736326 0.689 NM_178821
WDR69
WD repeat domain 69
chr22_-_20104695 0.687 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr6_-_109761707 0.681 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr1_-_16162341 0.679 FLJ37453
uncharacterized LOC729614
chr17_+_8924822 0.670 NM_004822
NTN1
netrin 1
chrX_-_8700170 0.670 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr16_+_28303622 0.669 NM_001024401
SBK1
SH3-binding domain kinase 1
chr16_+_56225301 0.664 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr19_+_54057898 0.662 NM_001253801
ZNF331
zinc finger protein 331
chr7_+_116593554 0.655 ST7
suppression of tumorigenicity 7
chr14_+_100259445 0.654 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr2_+_121103670 0.647 NM_002193
INHBB
inhibin, beta B
chr19_-_460995 0.636 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr22_-_39268230 0.633 NM_014292
CBX6
chromobox homolog 6
chr9_-_136933552 0.632 BRD3
bromodomain containing 3
chr9_-_99382073 0.627 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr13_+_25254548 0.627 NM_001185085
NM_001676
ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

chr17_+_79651052 0.626


chr6_-_6007632 0.626 NM_016588
NRN1
neuritin 1
chr17_-_74137370 0.625 NM_001454
FOXJ1
forkhead box J1
chr13_+_24153426 0.624 NM_001204458
NM_018647
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr19_-_47734215 0.617 NM_014417
BBC3
BCL2 binding component 3
chr7_-_139876718 0.616 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_+_10442065 0.615 ROPN1L
rhophilin associated tail protein 1-like
chr1_-_109656478 0.613 NM_001122961
C1orf194
chromosome 1 open reading frame 194
chr9_-_139922705 0.611 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr15_-_90645704 0.610 NM_002168
IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr7_-_122526781 0.609 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr5_-_16617085 0.606 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr4_-_7044664 0.605 NM_153376
CCDC96
coiled-coil domain containing 96
chr11_+_111169965 0.602 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr22_-_39268214 0.601 CBX6
chromobox homolog 6
chr5_+_1008900 0.601 NM_033120
NKD2
naked cuticle homolog 2 (Drosophila)
chr16_-_4166185 0.598 NM_001116
ADCY9
adenylate cyclase 9
chr6_+_109762204 0.598 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr3_+_23987514 0.590 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr21_+_34442550 0.587 OLIG1
oligodendrocyte transcription factor 1
chr5_-_180018465 0.587 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr12_+_90103470 0.579 LOC338758
uncharacterized LOC338758
chr4_+_20255234 0.578 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr19_+_708766 0.576 NM_001040134
NM_002579
PALM

paralemmin

chrX_-_153714936 0.576 UBL4A
ubiquitin-like 4A
chr4_+_72052354 0.573 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr15_+_78556901 0.573 NM_001130182
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chrX_-_153714969 0.573 UBL4A
ubiquitin-like 4A
chr1_-_38218573 0.572 EPHA10
EPH receptor A10
chr9_+_34958171 0.568 NM_015297
KIAA1045
KIAA1045
chr6_-_111136288 0.566 CDK19
cyclin-dependent kinase 19
chr18_-_5296013 0.565 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr22_-_39268169 0.563 CBX6
chromobox homolog 6
chr2_-_207630009 0.562 NM_001039845
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr5_+_176873795 0.561 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr6_-_43337125 0.555 NM_014345
ZNF318
zinc finger protein 318
chr6_-_91006460 0.555 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr20_-_590909 0.554 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr16_+_84178864 0.554 NM_178452
DNAAF1
dynein, axonemal, assembly factor 1
chr19_+_32896515 0.549 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr3_-_128206704 0.548 NM_001145662
GATA2
GATA binding protein 2
chr22_-_20104745 0.544 NM_022727
NM_182984
TRMT2A

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

chr17_+_2240795 0.542 NM_014853
NM_001098509
SGSM2

small G protein signaling modulator 2

chr3_-_53080038 0.537 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr2_-_99771186 0.536 NM_025244
TSGA10
testis specific, 10
chr2_+_217498082 0.535 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr19_+_3094266 0.535 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr14_-_23755232 0.535 HOMEZ
homeobox and leucine zipper encoding
chr19_-_18717467 0.531 CRLF1
cytokine receptor-like factor 1
chr12_+_49524648 0.531


chr6_+_126070813 0.528 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr17_-_27893926 0.527 NM_198147
ABHD15
abhydrolase domain containing 15
chr12_+_133614052 0.526 ZNF84
zinc finger protein 84
chr10_+_12391728 0.525 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr9_-_13279562 0.523 MPDZ
multiple PDZ domain protein
chr13_+_113622758 0.523 MCF2L
MCF.2 cell line derived transforming sequence-like
chr14_+_74003817 0.522 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr12_+_133614138 0.522 ZNF84
zinc finger protein 84
chr14_-_23755308 0.520 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr12_+_56660913 0.516 COQ10A
coenzyme Q10 homolog A (S. cerevisiae)
chr6_-_111136190 0.515 CDK19
cyclin-dependent kinase 19
chr11_-_75062650 0.514 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr4_+_17578838 0.512 NM_015907
LAP3
leucine aminopeptidase 3
chr8_-_144241918 0.509 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr2_+_232573249 0.508 PTMA
prothymosin, alpha
chr3_+_169755782 0.507 GPR160
G protein-coupled receptor 160
chr20_+_53092131 0.506 NM_018431
DOK5
docking protein 5
chr1_-_59248287 0.505 JUN
jun proto-oncogene

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 1.71e-12 GO:0007399 nervous system development
1.35 1.94e-12 GO:0010468 regulation of gene expression
1.36 3.24e-12 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.75 2.32e-11 GO:0010629 negative regulation of gene expression
1.32 6.02e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 7.00e-11 GO:0010556 regulation of macromolecule biosynthetic process
1.17 7.11e-11 GO:0050794 regulation of cellular process
1.36 1.51e-10 GO:0006355 regulation of transcription, DNA-dependent
1.56 2.00e-10 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.35 2.12e-10 GO:0051252 regulation of RNA metabolic process
1.31 7.02e-10 GO:0031326 regulation of cellular biosynthetic process
1.30 8.53e-10 GO:0009889 regulation of biosynthetic process
1.74 1.58e-09 GO:0045892 negative regulation of transcription, DNA-dependent
1.53 1.73e-09 GO:0009892 negative regulation of metabolic process
1.67 2.01e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.25 2.07e-09 GO:0080090 regulation of primary metabolic process
1.37 2.11e-09 GO:0006464 protein modification process
1.73 2.16e-09 GO:0051253 negative regulation of RNA metabolic process
1.29 3.14e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.55 3.46e-09 GO:0010605 negative regulation of macromolecule metabolic process
1.26 5.72e-09 GO:0060255 regulation of macromolecule metabolic process
1.66 6.11e-09 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.24 7.58e-09 GO:0031323 regulation of cellular metabolic process
1.35 1.61e-08 GO:0043412 macromolecule modification
1.14 1.79e-08 GO:0050789 regulation of biological process
1.63 2.55e-08 GO:0010558 negative regulation of macromolecule biosynthetic process
1.24 3.31e-08 GO:0007275 multicellular organismal development
1.38 3.96e-08 GO:0023051 regulation of signaling
1.60 4.31e-08 GO:0009890 negative regulation of biosynthetic process
1.61 4.31e-08 GO:0031327 negative regulation of cellular biosynthetic process
1.64 6.46e-08 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 6.47e-08 GO:0032502 developmental process
1.22 8.85e-08 GO:0019222 regulation of metabolic process
1.48 9.68e-08 GO:0006793 phosphorus metabolic process
1.48 9.68e-08 GO:0006796 phosphate metabolic process
1.82 1.23e-07 GO:0016568 chromatin modification
1.62 1.92e-07 GO:0051172 negative regulation of nitrogen compound metabolic process
1.50 3.53e-07 GO:0031324 negative regulation of cellular metabolic process
1.49 6.09e-07 GO:0022008 neurogenesis
1.48 8.18e-07 GO:0048468 cell development
1.12 1.11e-06 GO:0065007 biological regulation
1.30 1.20e-06 GO:0048523 negative regulation of cellular process
1.50 1.48e-06 GO:0016310 phosphorylation
1.23 2.45e-06 GO:0048856 anatomical structure development
1.48 2.54e-06 GO:0048699 generation of neurons
1.73 2.60e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.52 5.04e-06 GO:0006468 protein phosphorylation
1.27 6.48e-06 GO:0048519 negative regulation of biological process
1.74 6.58e-06 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.24 8.84e-06 GO:0048731 system development
1.67 1.20e-05 GO:0032583 regulation of gene-specific transcription
1.51 2.66e-05 GO:0045595 regulation of cell differentiation
1.34 2.83e-05 GO:0009966 regulation of signal transduction
1.50 3.23e-05 GO:0030182 neuron differentiation
1.28 4.38e-05 GO:0030154 cell differentiation
1.58 4.69e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 4.89e-05 GO:0048869 cellular developmental process
1.33 6.69e-05 GO:0009653 anatomical structure morphogenesis
1.58 6.93e-05 GO:0007417 central nervous system development
1.24 1.64e-04 GO:0044267 cellular protein metabolic process
1.58 1.95e-04 GO:0006325 chromatin organization
1.48 1.98e-04 GO:0009790 embryo development
1.52 2.51e-04 GO:0048666 neuron development
1.13 2.87e-04 GO:0044237 cellular metabolic process
2.19 3.69e-04 GO:0060541 respiratory system development
1.23 3.76e-04 GO:0048522 positive regulation of cellular process
1.48 6.34e-04 GO:0030030 cell projection organization
2.55 8.15e-04 GO:0051147 regulation of muscle cell differentiation
1.54 8.67e-04 GO:0000904 cell morphogenesis involved in differentiation
1.87 9.87e-04 GO:0032582 negative regulation of gene-specific transcription
1.58 1.04e-03 GO:0040008 regulation of growth
1.39 1.05e-03 GO:0050793 regulation of developmental process
1.15 1.18e-03 GO:0044260 cellular macromolecule metabolic process
1.35 1.21e-03 GO:0010646 regulation of cell communication
1.53 1.44e-03 GO:0031175 neuron projection development
1.17 1.62e-03 GO:0023052 signaling
1.21 2.08e-03 GO:0071842 cellular component organization at cellular level
1.47 2.83e-03 GO:0000902 cell morphogenesis
1.91 4.05e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
5.52 4.69e-03 GO:0060484 lung-associated mesenchyme development
1.61 4.97e-03 GO:0045597 positive regulation of cell differentiation
1.59 5.00e-03 GO:0007420 brain development
1.17 5.31e-03 GO:0016043 cellular component organization
1.42 5.33e-03 GO:0010628 positive regulation of gene expression
1.97 5.59e-03 GO:0016055 Wnt receptor signaling pathway
1.84 6.62e-03 GO:0016570 histone modification
1.66 7.06e-03 GO:0035295 tube development
1.43 7.90e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.13 8.43e-03 GO:0030323 respiratory tube development
1.43 9.16e-03 GO:0032989 cellular component morphogenesis
1.37 9.45e-03 GO:0051128 regulation of cellular component organization
1.06 1.09e-02 GO:0009987 cellular process
1.19 1.14e-02 GO:0048518 positive regulation of biological process
1.81 1.23e-02 GO:0016569 covalent chromatin modification
1.64 1.35e-02 GO:0007423 sensory organ development
1.38 1.40e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50 1.59e-02 GO:0051094 positive regulation of developmental process
1.55 1.76e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.40 1.91e-02 GO:0051254 positive regulation of RNA metabolic process
1.70 2.18e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.51 2.28e-02 GO:0007409 axonogenesis
1.65 2.28e-02 GO:0045596 negative regulation of cell differentiation
1.50 2.44e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.36 2.62e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.18 2.82e-02 GO:0071841 cellular component organization or biogenesis at cellular level
2.08 2.94e-02 GO:0030324 lung development
1.45 3.11e-02 GO:0032990 cell part morphogenesis
1.45 3.31e-02 GO:0048858 cell projection morphogenesis
1.53 3.59e-02 GO:0009792 embryo development ending in birth or egg hatching
1.53 3.80e-02 GO:0043009 chordate embryonic development
1.16 4.08e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 1.06e-13 GO:0044424 intracellular part
1.10 2.12e-13 GO:0005622 intracellular
1.21 2.51e-13 GO:0005634 nucleus
1.14 4.04e-13 GO:0043227 membrane-bounded organelle
1.14 8.70e-13 GO:0043231 intracellular membrane-bounded organelle
1.12 3.93e-12 GO:0043226 organelle
1.12 7.72e-12 GO:0043229 intracellular organelle
1.40 7.21e-04 GO:0044451 nucleoplasm part
1.52 1.55e-03 GO:0045202 synapse
1.09 1.57e-03 GO:0005737 cytoplasm
1.27 2.75e-03 GO:0005654 nucleoplasm
1.21 1.53e-02 GO:0031981 nuclear lumen
1.19 1.87e-02 GO:0044428 nuclear part
1.03 2.29e-02 GO:0044464 cell part
1.03 2.39e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 2.23e-13 GO:0005488 binding
1.50 1.00e-09 GO:0030528 transcription regulator activity
1.14 3.14e-09 GO:0005515 protein binding
1.26 2.64e-06 GO:0003677 DNA binding
1.19 3.38e-06 GO:0046872 metal ion binding
1.27 6.61e-06 GO:0008270 zinc ion binding
1.18 1.30e-05 GO:0043169 cation binding
1.18 1.58e-05 GO:0043167 ion binding
1.40 1.72e-05 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.72e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.51 1.86e-05 GO:0004672 protein kinase activity
1.57 2.91e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.45 3.24e-05 GO:0019899 enzyme binding
1.45 3.74e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.45 4.24e-05 GO:0019199 transmembrane receptor protein kinase activity
1.47 4.79e-05 GO:0043565 sequence-specific DNA binding
1.19 5.95e-05 GO:0003676 nucleic acid binding
1.42 1.05e-04 GO:0016301 kinase activity
1.56 1.16e-04 GO:0030695 GTPase regulator activity
1.61 1.73e-04 GO:0003712 transcription cofactor activity
1.60 2.01e-04 GO:0000988 protein binding transcription factor activity
1.60 2.01e-04 GO:0000989 transcription factor binding transcription factor activity
1.22 6.32e-04 GO:0000166 nucleotide binding
1.22 6.98e-04 GO:0046914 transition metal ion binding
1.34 3.29e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.49 4.18e-03 GO:0019904 protein domain specific binding
2.37 4.73e-03 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.56 8.99e-03 GO:0016564 transcription repressor activity
1.77 1.57e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.83 2.03e-02 GO:0004713 protein tyrosine kinase activity
1.68 2.18e-02 GO:0010843 promoter binding
1.20 2.21e-02 GO:0017076 purine nucleotide binding
1.55 2.34e-02 GO:0005083 small GTPase regulator activity
1.79 2.45e-02 GO:0003714 transcription corepressor activity
1.20 2.90e-02 GO:0032553 ribonucleotide binding
1.20 2.90e-02 GO:0032555 purine ribonucleotide binding
1.22 3.27e-02 GO:0030554 adenyl nucleotide binding
1.64 4.05e-02 GO:0000975 regulatory region DNA binding
1.64 4.05e-02 GO:0001067 regulatory region nucleic acid binding
1.64 4.05e-02 GO:0044212 transcription regulatory region DNA binding
2.45 4.19e-02 GO:0046332 SMAD binding
1.51 4.64e-02 GO:0016563 transcription activator activity
1.22 4.88e-02 GO:0032559 adenyl ribonucleotide binding