Motif ID: ZNF143.p2

Z-value: 2.359


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF143chr11_+_94825110.495.8e-03Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_1723212 7.983 NM_006342
 TACC3
transforming, acidic coiled-coil containing protein 3
chr19_-_48673559 7.250 NM_000234
 LIG1
ligase I, DNA, ATP-dependent
chr17_+_76210276 6.166 NM_001012270
NM_001012271
NM_001168
 BIRC5


baculoviral IAP repeat containing 5


chr15_+_40453263 5.320 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr15_+_40453209 5.161 NM_001211
 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_+_1723233 4.925 TACC3
transforming, acidic coiled-coil containing protein 3
chr17_+_76210329 4.576 BIRC5
baculoviral IAP repeat containing 5
chr1_+_45205533 4.119 KIF2C
kinesin family member 2C
chr1_+_45205558 3.874 KIF2C
kinesin family member 2C
chr1_-_54303933 3.336 TMEM48
transmembrane protein 48
chr1_+_45205466 3.311 NM_006845
 KIF2C
kinesin family member 2C
chr12_+_53895065 2.763 TARBP2
TAR (HIV-1) RNA binding protein 2
chr19_-_2456954 2.626 NM_032737
 LMNB2
lamin B2
chr1_-_54304107 2.577 NM_001168551
NM_018087
 TMEM48

transmembrane protein 48

chr22_-_41682187 2.462 NM_002883
 RANGAP1
Ran GTPase activating protein 1
chr22_-_41682169 2.387 RANGAP1
Ran GTPase activating protein 1
chr12_-_6961044 2.296 CDCA3
cell division cycle associated 3
chr14_+_97263681 2.280 NM_003384
 VRK1
vaccinia related kinase 1
chr13_-_103426075 2.268 C13orf27
chromosome 13 open reading frame 27
chr12_-_2986095 2.232 FOXM1
forkhead box M1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
enrichment   p-value GO term description
3.21 1.29e-03 GO:0051352 negative regulation of ligase activity
3.21 1.29e-03 GO:0051444 negative regulation of ubiquitin-protein ligase activity
3.05 1.04e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.93 4.15e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.92 7.80e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.87 2.75e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.82 5.60e-03 GO:0031397 negative regulation of protein ubiquitination
2.72 1.08e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
2.71 2.97e-02 GO:0000236 mitotic prometaphase
2.61 2.43e-02 GO:0051340 regulation of ligase activity
2.40 1.94e-05 GO:0000075 cell cycle checkpoint
2.39 1.97e-02 GO:0007093 mitotic cell cycle checkpoint
2.36 2.53e-05 GO:0071156 regulation of cell cycle arrest
2.32 4.78e-03 GO:0010498 proteasomal protein catabolic process
2.32 4.78e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.29 6.55e-04 GO:0022613 ribonucleoprotein complex biogenesis
2.24 1.53e-02 GO:0031400 negative regulation of protein modification process
2.24 3.70e-02 GO:0031396 regulation of protein ubiquitination
2.23 1.10e-03 GO:0071843 cellular component biogenesis at cellular level
2.19 1.52e-12 GO:0000278 mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
4.49 4.51e-03 GO:0044452 nucleolar part
2.98 1.62e-03 GO:0000777 condensed chromosome kinetochore
2.92 1.39e-03 GO:0000779 condensed chromosome, centromeric region
2.67 4.35e-03 GO:0000776 kinetochore
2.42 5.95e-04 GO:0000793 condensed chromosome
2.34 9.23e-05 GO:0005819 spindle
2.28 6.20e-03 GO:0005681 spliceosomal complex
2.23 7.65e-03 GO:0000775 chromosome, centromeric region
2.20 1.31e-02 GO:0000151 ubiquitin ligase complex
1.98 4.53e-05 GO:0005815 microtubule organizing center
1.86 4.10e-02 GO:0005813 centrosome
1.73 2.33e-04 GO:0030529 ribonucleoprotein complex
1.72 8.36e-06 GO:0015630 microtubule cytoskeleton
1.69 1.26e-03 GO:0005730 nucleolus
1.64 2.12e-03 GO:0005694 chromosome
1.61 2.21e-16 GO:0044428 nuclear part
1.60 4.20e-13 GO:0031981 nuclear lumen
1.57 6.00e-08 GO:0005654 nucleoplasm
1.53 4.15e-13 GO:0070013 intracellular organelle lumen
1.52 4.39e-13 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.44 6.79e-03 GO:0051082 unfolded protein binding
1.56 4.33e-04 GO:0003723 RNA binding
1.42 9.41e-05 GO:0005524 ATP binding
1.41 1.86e-04 GO:0032559 adenyl ribonucleotide binding
1.40 2.78e-04 GO:0030554 adenyl nucleotide binding
1.36 2.02e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.35 4.98e-04 GO:0032553 ribonucleotide binding
1.35 4.98e-04 GO:0032555 purine ribonucleotide binding
1.35 5.22e-04 GO:0017076 purine nucleotide binding
1.33 1.31e-04 GO:0000166 nucleotide binding
1.24 1.83e-03 GO:0003676 nucleic acid binding
1.20 4.28e-09 GO:0005515 protein binding
1.11 1.87e-08 GO:0005488 binding