Motif ID: ZNF143.p2

Z-value: 2.359


Transcription factors associated with ZNF143.p2:

Gene SymbolEntrez IDGene Name
ZNF143 7702 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF143chr11_+_94825110.495.8e-03Click!


Activity profile for motif ZNF143.p2.

activity profile for motif ZNF143.p2


Sorted Z-values histogram for motif ZNF143.p2

Sorted Z-values for motif ZNF143.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF143.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_1723212 7.983 NM_006342
TACC3
transforming, acidic coiled-coil containing protein 3
chr19_-_48673559 7.250 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr17_+_76210276 6.166 NM_001012270
NM_001012271
NM_001168
BIRC5


baculoviral IAP repeat containing 5


chr15_+_40453263 5.320 BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr15_+_40453209 5.161 NM_001211
BUB1B
budding uninhibited by benzimidazoles 1 homolog beta (yeast)
chr4_+_1723233 4.925 TACC3
transforming, acidic coiled-coil containing protein 3
chr17_+_76210329 4.576 BIRC5
baculoviral IAP repeat containing 5
chr1_+_45205533 4.119 KIF2C
kinesin family member 2C
chr1_+_45205558 3.874 KIF2C
kinesin family member 2C
chr1_-_54303933 3.336 TMEM48
transmembrane protein 48
chr1_+_45205466 3.311 NM_006845
KIF2C
kinesin family member 2C
chr12_+_53895065 2.763 TARBP2
TAR (HIV-1) RNA binding protein 2
chr19_-_2456954 2.626 NM_032737
LMNB2
lamin B2
chr1_-_54304107 2.577 NM_001168551
NM_018087
TMEM48

transmembrane protein 48

chr22_-_41682187 2.462 NM_002883
RANGAP1
Ran GTPase activating protein 1
chr22_-_41682169 2.387 RANGAP1
Ran GTPase activating protein 1
chr12_-_6961044 2.296 CDCA3
cell division cycle associated 3
chr14_+_97263681 2.280 NM_003384
VRK1
vaccinia related kinase 1
chr13_-_103426075 2.268 C13orf27
chromosome 13 open reading frame 27
chr12_-_2986095 2.232 FOXM1
forkhead box M1
chr5_+_137514416 2.067 NM_005733
KIF20A
kinesin family member 20A
chr7_-_134001749 2.055 NM_032826
SLC35B4
solute carrier family 35, member B4
chr1_+_38158129 2.023 NM_018101
CDCA8
cell division cycle associated 8
chr5_+_137514753 2.006 KIF20A
kinesin family member 20A
chr12_+_53895376 1.983 NM_134324
TARBP2
TAR (HIV-1) RNA binding protein 2
chr19_+_3185860 1.957 NM_020170
NCLN
nicalin
chr13_-_103426148 1.956 NM_138779
C13orf27
chromosome 13 open reading frame 27
chr14_-_77787023 1.948 NM_013382
POMT2
protein-O-mannosyltransferase 2
chr9_-_19102898 1.925 NM_017645
HAUS6
HAUS augmin-like complex, subunit 6
chr7_+_94285620 1.894 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr19_+_3185965 1.887 NCLN
nicalin
chr13_-_103426130 1.876 C13orf27
chromosome 13 open reading frame 27
chr1_+_38158176 1.861 CDCA8
cell division cycle associated 8
chr7_+_94285736 1.853 PEG10
paternally expressed 10
chr7_+_94285676 1.784 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr19_+_3185927 1.780 NCLN
nicalin
chr12_-_2986299 1.766 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr16_+_23690234 1.740 PLK1
polo-like kinase 1
chr2_+_219187975 1.733 PNKD
paroxysmal nonkinesigenic dyskinesia
chr2_+_219187858 1.705 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr21_-_15755439 1.694 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr6_-_43596764 1.652 GTPBP2
GTP binding protein 2
chr11_-_113644476 1.643 NM_004724
ZW10
ZW10, kinetochore associated, homolog (Drosophila)
chr16_+_23690160 1.642 PLK1
polo-like kinase 1
chr1_+_38158189 1.638 CDCA8
cell division cycle associated 8
chr16_+_23690190 1.632 PLK1
polo-like kinase 1
chr11_-_113644392 1.630 ZW10
ZW10, kinetochore associated, homolog (Drosophila)
chr1_-_1051458 1.615 C1orf159
chromosome 1 open reading frame 159
chr3_-_52188705 1.612 NM_001161580
NM_001161581
NM_015426
POC1A


POC1 centriolar protein homolog A (Chlamydomonas)


chr11_+_61560401 1.580 FEN1
flap structure-specific endonuclease 1
chr4_-_2965036 1.568 NOP14
NOP14 nucleolar protein homolog (yeast)
chr17_+_38444130 1.558 CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr1_-_26232643 1.552 NM_203401
STMN1
stathmin 1
chr17_+_38444134 1.546 NM_001254
CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr4_-_159592979 1.538 NM_001008393
C4orf46
chromosome 4 open reading frame 46
chr16_+_23690212 1.526 PLK1
polo-like kinase 1
chr10_+_94352809 1.520 NM_004523
KIF11
kinesin family member 11
chr16_+_23690191 1.515 NM_005030
PLK1
polo-like kinase 1
chr17_+_38444151 1.513 CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr19_+_54618789 1.473 NM_015629
PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr2_-_169746921 1.472 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr19_+_12917391 1.460 RNASEH2A
ribonuclease H2, subunit A
chr2_-_26205327 1.455 KIF3C
kinesin family member 3C
chr10_+_94352873 1.423 KIF11
kinesin family member 11
chr22_+_19467467 1.396 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr7_-_150754934 1.388 CDK5
cyclin-dependent kinase 5
chr6_-_32805819 1.386 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_43596919 1.375 NM_019096
GTPBP2
GTP binding protein 2
chr11_+_450346 1.368 PTDSS2
phosphatidylserine synthase 2
chr11_+_64808375 1.364 NM_013299
SAC3D1
SAC3 domain containing 1
chr3_+_160117444 1.361 SMC4
structural maintenance of chromosomes 4
chr5_-_138775213 1.352 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr11_+_450260 1.343 NM_030783
PTDSS2
phosphatidylserine synthase 2
chr19_+_4304590 1.339 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr7_-_150754979 1.334 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chr19_-_44285012 1.333 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr17_-_41322211 1.321 BRCA1
breast cancer 1, early onset
chr1_+_244816385 1.314 PPPDE1
PPPDE peptidase domain containing 1
chr10_+_94352960 1.293 KIF11
kinesin family member 11
chr6_+_11094265 1.287 NM_001135575
C6orf228
chromosome 6 open reading frame 228
chr13_-_50656088 1.271 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr6_+_11093991 1.258 C6orf228
chromosome 6 open reading frame 228
chr13_-_21750617 1.258 NM_001166017
NM_145061
SKA3

spindle and kinetochore associated complex subunit 3

chr2_+_25016174 1.241 NM_001199803
NM_024322
CENPO

centromere protein O

chr20_+_44441671 1.234 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr11_+_64808395 1.224 SAC3D1
SAC3 domain containing 1
chr8_+_99129488 1.217 NM_001145860
NM_001145861
POP1

processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)

chr9_-_19102648 1.213 HAUS6
HAUS augmin-like complex, subunit 6
chr4_-_2965147 1.202 NOP14
NOP14 nucleolar protein homolog (yeast)
chr19_-_44285407 1.191 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_202316391 1.191 NM_001206864
NM_018571
STRADB

STE20-related kinase adaptor beta

chr10_+_91461333 1.169 NM_016195
KIF20B
kinesin family member 20B
chr11_+_61560352 1.159 FEN1
flap structure-specific endonuclease 1
chr6_+_30875962 1.156 NM_001517
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
chr7_-_134001502 1.144 SLC35B4
solute carrier family 35, member B4
chr6_-_167571315 1.137 NM_005299
GPR31
G protein-coupled receptor 31
chr4_-_47916498 1.136 NM_152995
NFXL1
nuclear transcription factor, X-box binding-like 1
chr1_+_224544597 1.134 CNIH4
cornichon homolog 4 (Drosophila)
chr12_+_56498102 1.133 NM_006191
PA2G4
proliferation-associated 2G4, 38kDa
chr9_-_19102906 1.132 HAUS6
HAUS augmin-like complex, subunit 6
chr1_-_197115566 1.126 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr12_-_57146081 1.122 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr7_-_111846384 1.119 NM_014705
DOCK4
dedicator of cytokinesis 4
chr8_+_27631902 1.105 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr17_+_900329 1.102 NM_013337
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr11_+_61560108 1.101 NM_004111
FEN1
flap structure-specific endonuclease 1
chr11_-_60673854 1.097 PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)
chr7_+_107301079 1.096 NM_000441
SLC26A4
solute carrier family 26, member 4
chr3_-_98241722 1.095 CLDND1
claudin domain containing 1
chr20_+_32399128 1.093 CHMP4B
charged multivesicular body protein 4B
chr19_+_12917409 1.093 NM_006397
RNASEH2A
ribonuclease H2, subunit A
chr11_-_113644432 1.085 ZW10
ZW10, kinetochore associated, homolog (Drosophila)
chr3_-_98241748 1.080 CLDND1
claudin domain containing 1
chr12_+_53894704 1.080 NM_004178
NM_134323
TARBP2

TAR (HIV-1) RNA binding protein 2

chr5_+_149737296 1.073 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr19_-_5790913 1.070 DUS3L
dihydrouridine synthase 3-like (S. cerevisiae)
chr16_+_58426297 1.067 NM_001126129
NM_001126130
NM_022770
GINS3


GINS complex subunit 3 (Psf3 homolog)


chr10_-_121356527 1.066 NM_001033925
NM_003252
TIAL1

TIA1 cytotoxic granule-associated RNA binding protein-like 1

chr14_-_105487421 1.066 NM_017955
NM_145701
CDCA4

cell division cycle associated 4

chr3_-_98241824 1.063 NM_001040181
NM_001040182
NM_001040183
NM_001040199
NM_001040200
NM_019895
CLDND1





claudin domain containing 1





chr10_-_105110844 1.053 PCGF6
polycomb group ring finger 6
chr3_+_172468469 1.044 ECT2
epithelial cell transforming sequence 2 oncogene
chr1_+_156024516 1.039 NM_001145264
NM_014017
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr1_-_1051735 1.029 NM_017891
C1orf159
chromosome 1 open reading frame 159
chr11_+_2421983 1.024 TSSC4
tumor suppressing subtransferable candidate 4
chr3_-_186524226 1.010 NM_002916
RFC4
replication factor C (activator 1) 4, 37kDa
chr10_-_121356474 1.007 TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr20_-_62339205 1.004 ARFRP1
ADP-ribosylation factor related protein 1
chr13_-_103451271 1.000 NM_024089
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr10_-_13390189 0.987 NM_001195602
NM_001195604
NM_012247
SEPHS1


selenophosphate synthetase 1


chr16_-_58718607 0.985 NM_018231
SLC38A7
solute carrier family 38, member 7
chr3_-_186524483 0.977 NM_181573
RFC4
replication factor C (activator 1) 4, 37kDa
chr22_+_46692637 0.970 NM_016426
GTSE1
G-2 and S-phase expressed 1
chr1_+_107599266 0.969 NM_018137
PRMT6
protein arginine methyltransferase 6
chr7_-_94285477 0.958 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr12_-_121454285 0.958 NM_022895
C12orf43
chromosome 12 open reading frame 43
chr4_-_104119475 0.957 NM_001813
CENPE
centromere protein E, 312kDa
chr17_+_66031814 0.957 NM_002266
KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr2_-_224903933 0.956 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr14_+_105956519 0.954 NM_001134877
C14orf80
chromosome 14 open reading frame 80
chr12_-_121454210 0.951 C12orf43
chromosome 12 open reading frame 43
chr7_-_94285426 0.948 SGCE
sarcoglycan, epsilon
chr16_+_3074027 0.948 NM_001142350
NM_024339
THOC6

THO complex 6 homolog (Drosophila)

chr17_+_66031885 0.940 KPNA2
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr7_-_94285372 0.939 SGCE
sarcoglycan, epsilon
chr15_+_75182351 0.935 NM_002435
MPI
mannose phosphate isomerase
chr16_+_88870185 0.924 NM_030928
CDT1
chromatin licensing and DNA replication factor 1
chr10_-_105110823 0.915 PCGF6
polycomb group ring finger 6
chr14_-_105487413 0.912 CDCA4
cell division cycle associated 4
chr10_-_105110890 0.911 NM_001011663
NM_032154
PCGF6

polycomb group ring finger 6

chr19_-_633474 0.910 POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr22_+_19467413 0.910 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr11_+_134123406 0.902 NM_014384
ACAD8
acyl-CoA dehydrogenase family, member 8
chr12_+_53491448 0.890 IGFBP6
insulin-like growth factor binding protein 6
chr20_-_32891075 0.885 NM_000687
AHCY
adenosylhomocysteinase
chr15_+_40987326 0.879 NM_001164270
NM_002875
NM_133487
NM_001164269
RAD51



RAD51 homolog (S. cerevisiae)



chr19_-_633563 0.879 NM_005035
POLRMT
polymerase (RNA) mitochondrial (DNA directed)
chr1_-_26233367 0.867 NM_203399
STMN1
stathmin 1
chr17_+_15848230 0.866 NM_000676
ADORA2B
adenosine A2b receptor
chr13_-_31736031 0.863 NM_006644
HSPH1
heat shock 105kDa/110kDa protein 1
chr2_-_26205437 0.861 NM_002254
KIF3C
kinesin family member 3C
chr19_+_7600581 0.855 NM_001166114
PNPLA6
patatin-like phospholipase domain containing 6
chr7_-_150924220 0.851 NM_005692
NM_007189
ABCF2

ATP-binding cassette, sub-family F (GCN20), member 2

chr12_+_56498414 0.831 PA2G4
proliferation-associated 2G4, 38kDa
chr9_+_116037955 0.825 PRPF4
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr22_+_26825220 0.823 NM_020437
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr16_+_3074060 0.820 THOC6
THO complex 6 homolog (Drosophila)
chr6_+_57037058 0.820 NM_004282
BAG2
BCL2-associated athanogene 2
chr3_-_48229800 0.817 NM_001789
NM_201567
CDC25A

cell division cycle 25 homolog A (S. pombe)

chr16_+_88870214 0.816 CDT1
chromatin licensing and DNA replication factor 1
chr16_+_3074041 0.812 THOC6
THO complex 6 homolog (Drosophila)
chr6_-_119670897 0.810 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr12_+_32832272 0.808 DNM1L
dynamin 1-like
chr2_+_85360373 0.802 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr6_-_116989901 0.799 NM_145062
ZUFSP
zinc finger with UFM1-specific peptidase domain
chr5_+_149737201 0.797 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr20_+_30326903 0.796 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr1_-_231114596 0.795 TTC13
tetratricopeptide repeat domain 13
chr19_+_507475 0.794 NM_033513
TPGS1
tubulin polyglutamylase complex subunit 1
chr3_-_139258373 0.794 RBP1
retinol binding protein 1, cellular
chr12_+_32832128 0.794 NM_005690
NM_012062
NM_012063
DNM1L


dynamin 1-like


chr4_-_2965111 0.794 NM_003703
NOP14
NOP14 nucleolar protein homolog (yeast)
chr20_-_62339309 0.784 NM_001134758
NM_003224
ARFRP1

ADP-ribosylation factor related protein 1

chr10_+_103892786 0.782 NM_015062
PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr1_-_231114617 0.776 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr5_-_55008079 0.775 SLC38A9
solute carrier family 38, member 9
chr1_-_10532603 0.772 NM_004401
NM_213566
DFFA

DNA fragmentation factor, 45kDa, alpha polypeptide

chr1_+_224544550 0.768 CNIH4
cornichon homolog 4 (Drosophila)
chr3_+_133494275 0.767 TF
transferrin
chr16_-_279338 0.765 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr3_-_52188398 0.765 POC1A
POC1 centriolar protein homolog A (Chlamydomonas)
chr17_-_5322982 0.764 NM_002532
NUP88
nucleoporin 88kDa
chr16_-_4588379 0.761 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr1_-_6453362 0.760 ACOT7
acyl-CoA thioesterase 7
chr8_-_28747697 0.760 NM_001145159
NM_018250
INTS9

integrator complex subunit 9

chr10_-_13390018 0.759 SEPHS1
selenophosphate synthetase 1
chr3_-_98241683 0.758 CLDND1
claudin domain containing 1
chr12_-_51477299 0.758 NM_030809
CSRNP2
cysteine-serine-rich nuclear protein 2
chr10_-_129924467 0.749 NM_001145966
NM_002417
MKI67

antigen identified by monoclonal antibody Ki-67

chr6_-_110501164 0.746 NM_001024934
NM_001024935
NM_001024936
NM_003931
WASF1



WAS protein family, member 1




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 2.40e-18 GO:0044260 cellular macromolecule metabolic process
1.33 7.57e-13 GO:0043170 macromolecule metabolic process
2.19 1.52e-12 GO:0000278 mitotic cell cycle
1.27 4.01e-12 GO:0044237 cellular metabolic process
1.53 2.30e-11 GO:0090304 nucleic acid metabolic process
1.25 5.06e-11 GO:0044238 primary metabolic process
1.13 3.75e-10 GO:0009987 cellular process
1.43 8.93e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 1.48e-09 GO:0007049 cell cycle
1.94 3.09e-09 GO:0022403 cell cycle phase
1.83 1.34e-08 GO:0022402 cell cycle process
1.20 9.77e-08 GO:0008152 metabolic process
1.88 2.82e-07 GO:0006396 RNA processing
1.52 3.35e-07 GO:0006996 organelle organization
1.34 3.70e-07 GO:0006807 nitrogen compound metabolic process
1.49 4.98e-07 GO:0016070 RNA metabolic process
1.34 6.30e-07 GO:0034641 cellular nitrogen compound metabolic process
1.46 2.22e-06 GO:0010467 gene expression
1.36 2.40e-06 GO:0071841 cellular component organization or biogenesis at cellular level
2.18 1.15e-05 GO:0051325 interphase
2.18 1.47e-05 GO:0051329 interphase of mitotic cell cycle
2.40 1.94e-05 GO:0000075 cell cycle checkpoint
2.36 2.53e-05 GO:0071156 regulation of cell cycle arrest
1.84 3.45e-05 GO:0016071 mRNA metabolic process
2.14 3.76e-05 GO:0000087 M phase of mitotic cell cycle
2.05 4.06e-05 GO:0010564 regulation of cell cycle process
1.35 5.86e-05 GO:0044267 cellular protein metabolic process
2.13 8.10e-05 GO:0000280 nuclear division
2.13 8.10e-05 GO:0007067 mitosis
2.10 1.08e-04 GO:0048285 organelle fission
1.33 1.08e-04 GO:0071842 cellular component organization at cellular level
1.73 1.88e-04 GO:0051726 regulation of cell cycle
2.14 2.18e-04 GO:0007346 regulation of mitotic cell cycle
2.29 6.55e-04 GO:0022613 ribonucleoprotein complex biogenesis
1.84 7.02e-04 GO:0000279 M phase
2.23 1.10e-03 GO:0071843 cellular component biogenesis at cellular level
3.21 1.29e-03 GO:0051352 negative regulation of ligase activity
3.21 1.29e-03 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.25 1.61e-03 GO:0071840 cellular component organization or biogenesis
2.04 1.71e-03 GO:0034660 ncRNA metabolic process
2.93 4.15e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.94 4.22e-03 GO:0008380 RNA splicing
1.82 4.45e-03 GO:0006397 mRNA processing
2.32 4.78e-03 GO:0010498 proteasomal protein catabolic process
2.32 4.78e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
2.82 5.60e-03 GO:0031397 negative regulation of protein ubiquitination
1.69 5.63e-03 GO:0044265 cellular macromolecule catabolic process
2.92 7.80e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.05 1.04e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.72 1.08e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
1.85 1.27e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
2.24 1.53e-02 GO:0031400 negative regulation of protein modification process
2.13 1.54e-02 GO:0034470 ncRNA processing
1.62 1.61e-02 GO:0006259 DNA metabolic process
2.39 1.97e-02 GO:0007093 mitotic cell cycle checkpoint
1.81 2.30e-02 GO:0044257 cellular protein catabolic process
1.24 2.32e-02 GO:0019538 protein metabolic process
2.61 2.43e-02 GO:0051340 regulation of ligase activity
1.83 2.53e-02 GO:0019941 modification-dependent protein catabolic process
2.06 2.65e-02 GO:0000375 RNA splicing, via transesterification reactions
2.87 2.75e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.22 2.83e-02 GO:0016043 cellular component organization
2.71 2.97e-02 GO:0000236 mitotic prometaphase
1.82 3.08e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.24 3.70e-02 GO:0031396 regulation of protein ubiquitination
1.76 4.38e-02 GO:0030163 protein catabolic process
1.63 4.83e-02 GO:0006974 response to DNA damage stimulus
1.57 4.96e-02 GO:0009057 macromolecule catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 4.43e-36 GO:0005622 intracellular
1.22 5.20e-36 GO:0044424 intracellular part
1.27 5.32e-27 GO:0043227 membrane-bounded organelle
1.27 1.04e-26 GO:0043231 intracellular membrane-bounded organelle
1.24 1.04e-25 GO:0043229 intracellular organelle
1.24 1.41e-25 GO:0043226 organelle
1.34 1.23e-18 GO:0005634 nucleus
1.23 3.61e-17 GO:0005737 cytoplasm
1.61 2.21e-16 GO:0044428 nuclear part
1.31 4.86e-15 GO:0044422 organelle part
1.31 5.07e-15 GO:0044446 intracellular organelle part
1.53 4.15e-13 GO:0070013 intracellular organelle lumen
1.60 4.20e-13 GO:0031981 nuclear lumen
1.52 4.39e-13 GO:0031974 membrane-enclosed lumen
1.51 3.82e-12 GO:0043233 organelle lumen
1.26 1.85e-11 GO:0044444 cytoplasmic part
1.34 3.80e-09 GO:0032991 macromolecular complex
1.57 6.00e-08 GO:0005654 nucleoplasm
1.42 5.13e-07 GO:0005829 cytosol
1.06 2.17e-06 GO:0044464 cell part
1.06 2.26e-06 GO:0005623 cell
1.72 8.36e-06 GO:0015630 microtubule cytoskeleton
1.31 8.50e-06 GO:0043234 protein complex
1.32 1.31e-05 GO:0043228 non-membrane-bounded organelle
1.32 1.31e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.98 4.53e-05 GO:0005815 microtubule organizing center
2.34 9.23e-05 GO:0005819 spindle
1.73 2.33e-04 GO:0030529 ribonucleoprotein complex
2.42 5.95e-04 GO:0000793 condensed chromosome
1.69 1.26e-03 GO:0005730 nucleolus
2.92 1.39e-03 GO:0000779 condensed chromosome, centromeric region
2.98 1.62e-03 GO:0000777 condensed chromosome kinetochore
1.64 2.12e-03 GO:0005694 chromosome
2.67 4.35e-03 GO:0000776 kinetochore
4.49 4.51e-03 GO:0044452 nucleolar part
2.28 6.20e-03 GO:0005681 spliceosomal complex
2.23 7.65e-03 GO:0000775 chromosome, centromeric region
2.20 1.31e-02 GO:0000151 ubiquitin ligase complex
1.34 2.88e-02 GO:0005739 mitochondrion
1.86 4.10e-02 GO:0005813 centrosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 4.28e-09 GO:0005515 protein binding
1.11 1.87e-08 GO:0005488 binding
1.42 9.41e-05 GO:0005524 ATP binding
1.33 1.31e-04 GO:0000166 nucleotide binding
1.41 1.86e-04 GO:0032559 adenyl ribonucleotide binding
1.36 2.02e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.40 2.78e-04 GO:0030554 adenyl nucleotide binding
1.56 4.33e-04 GO:0003723 RNA binding
1.35 4.98e-04 GO:0032553 ribonucleotide binding
1.35 4.98e-04 GO:0032555 purine ribonucleotide binding
1.35 5.22e-04 GO:0017076 purine nucleotide binding
1.24 1.83e-03 GO:0003676 nucleic acid binding
2.44 6.79e-03 GO:0051082 unfolded protein binding