Motif ID: ZNF148.p2

Z-value: 2.149


Transcription factors associated with ZNF148.p2:

Gene SymbolEntrez IDGene Name
ZNF148 7707 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF148chr3_-_125094003-0.571.1e-03Click!


Activity profile for motif ZNF148.p2.

activity profile for motif ZNF148.p2


Sorted Z-values histogram for motif ZNF148.p2

Sorted Z-values for motif ZNF148.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF148.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_4135701 9.345 NM_001166010
NM_006117
NM_206836
ECI2


enoyl-CoA delta isomerase 2


chr8_+_86376130 8.230 NM_000067
CA2
carbonic anhydrase II
chr20_+_3776905 7.828 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr19_+_35645640 7.710 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr19_+_35645614 7.486 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_20812271 7.459 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_35646006 7.147 FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_122231554 6.886 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chrX_-_153599719 6.336 FLNA
filamin A, alpha
chr19_-_51845377 6.095 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr12_-_125348266 5.724 SCARB1
scavenger receptor class B, member 1
chrX_-_153599581 5.577 FLNA
filamin A, alpha
chr19_+_6531009 5.495 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_+_32050510 5.072 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_-_19052032 4.989 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr19_+_2096930 4.853 IZUMO4
IZUMO family member 4
chr6_+_37137882 4.826 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr19_-_19051899 4.803 HOMER3
homer homolog 3 (Drosophila)
chr22_-_37915209 4.631 NM_014550
CARD10
caspase recruitment domain family, member 10
chr12_-_125348422 4.554 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr16_+_69141442 4.434 NM_005329
HAS3
hyaluronan synthase 3
chr17_-_34122547 4.343 NM_001032278
NM_024302
MMP28

matrix metallopeptidase 28

chrX_-_153602998 4.311 NM_001110556
NM_001456
FLNA

filamin A, alpha

chr11_-_71159442 4.225 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr3_-_52567708 4.156 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr11_-_71159371 4.151 DHCR7
7-dehydrocholesterol reductase
chr3_-_52567809 4.059 NT5DC2
5'-nucleotidase domain containing 2
chr9_-_139890984 3.989 NM_004669
CLIC3
chloride intracellular channel 3
chr12_-_125348346 3.987 SCARB1
scavenger receptor class B, member 1
chr22_+_31477231 3.966 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr19_+_54371125 3.961 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr19_+_54371150 3.914 MYADM
myeloid-associated differentiation marker
chr9_+_116327301 3.789 NM_134427
RGS3
regulator of G-protein signaling 3
chr19_+_1446268 3.772 APC2
adenomatosis polyposis coli 2
chrX_-_153602928 3.749 FLNA
filamin A, alpha
chr6_+_34204690 3.659 HMGA1
high mobility group AT-hook 1
chr1_-_204120909 3.650 ETNK2
ethanolamine kinase 2
chr19_-_51487070 3.634 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr18_+_12308236 3.632 TUBB6
tubulin, beta 6 class V
chr19_-_41859830 3.617 NM_000660
TGFB1
transforming growth factor, beta 1
chr1_-_6321034 3.597 NM_207370
GPR153
G protein-coupled receptor 153
chr19_+_54371170 3.579 MYADM
myeloid-associated differentiation marker
chr17_-_76921076 3.570 TIMP2
TIMP metallopeptidase inhibitor 2
chr10_-_5541401 3.538 NM_017422
CALML5
calmodulin-like 5
chr19_-_46283281 3.508


chr17_-_43209681 3.436 NM_133373
PLCD3
phospholipase C, delta 3
chr5_+_156887204 3.430 NIPAL4
NIPA-like domain containing 4
chr18_+_12308242 3.382 NM_032525
TUBB6
tubulin, beta 6 class V
chrX_-_48327739 3.371 SLC38A5
solute carrier family 38, member 5
chr22_+_44420154 3.291 NM_013327
PARVB
parvin, beta
chr12_-_54812936 3.267 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_50340979 3.267 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr1_+_26606443 3.249 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr12_-_2986299 3.240 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr19_-_19049790 3.219 NM_001145724
HOMER3
homer homolog 3 (Drosophila)
chr20_+_33759773 3.175 NM_006404
PROCR
protein C receptor, endothelial
chr7_-_143059144 3.173 NM_014690
FAM131B
family with sequence similarity 131, member B
chr19_-_11450254 3.147 NM_004283
RAB3D
RAB3D, member RAS oncogene family
chr19_-_51456159 3.119 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr11_+_844062 3.116 NM_001025234
TSPAN4
tetraspanin 4
chr22_-_36783851 3.095 MYH9
myosin, heavy chain 9, non-muscle
chr10_-_75634219 3.082 NM_001204492
NM_001222
NM_172169
NM_172170
NM_172171
NM_172173
CAMK2G





calcium/calmodulin-dependent protein kinase II gamma





chr10_+_94352809 3.073 NM_004523
KIF11
kinesin family member 11
chr2_-_26205327 3.053 KIF3C
kinesin family member 3C
chr1_+_44445548 3.044 NM_030587
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr15_-_34630203 3.028 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr1_+_26606621 3.019 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_54926604 2.988 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr19_+_676346 2.981 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr1_-_153044083 2.958 NM_001017418
SPRR2B
small proline-rich protein 2B
chr19_+_54926721 2.949 TTYH1
tweety homolog 1 (Drosophila)
chr19_+_917285 2.930 NM_032551
KISS1R
KISS1 receptor
chr5_-_134369841 2.923 NM_002653
PITX1
paired-like homeodomain 1
chr17_+_74380676 2.916 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr17_-_76921205 2.901 TIMP2
TIMP metallopeptidase inhibitor 2
chr15_-_34629941 2.885 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr15_-_91537724 2.882 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr17_+_2699731 2.869 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr17_+_37896219 2.854 NM_001242443
GRB7
growth factor receptor-bound protein 7
chr6_+_151186884 2.853 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr10_-_135150368 2.850 CALY
calcyon neuron-specific vesicular protein
chr22_+_33197744 2.843 TIMP3
TIMP metallopeptidase inhibitor 3
chr6_+_151186814 2.833 NM_001242767
NM_001242769
NM_015440
MTHFD1L


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr1_+_26606580 2.828 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr2_+_239756672 2.823 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr2_+_9346876 2.822 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr1_-_153013593 2.820 NM_006945
SPRR2D
small proline-rich protein 2D
chr1_-_204121144 2.817 NM_018208
ETNK2
ethanolamine kinase 2
chrX_+_64887534 2.802 MSN
moesin
chr19_-_1513187 2.798 NM_213604
ADAMTSL5
ADAMTS-like 5
chr11_-_441995 2.795 NM_001012302
ANO9
anoctamin 9
chr8_-_25315941 2.791 NM_017634
KCTD9
potassium channel tetramerisation domain containing 9
chr22_-_36783977 2.757 MYH9
myosin, heavy chain 9, non-muscle
chr19_-_11689591 2.740 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr12_-_2986095 2.730 FOXM1
forkhead box M1
chr19_-_41859519 2.713 TGFB1
transforming growth factor, beta 1
chr1_-_153067000 2.701 NM_001024209
SPRR2E
small proline-rich protein 2E
chr2_-_220408264 2.693 NM_024536
CHPF
chondroitin polymerizing factor
chr18_+_33877630 2.685 NM_025135
FHOD3
formin homology 2 domain containing 3
chr10_+_94352873 2.668 KIF11
kinesin family member 11
chr19_-_41859332 2.665 TGFB1
transforming growth factor, beta 1
chr6_+_34205369 2.664 HMGA1
high mobility group AT-hook 1
chr2_+_37571752 2.663 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr1_+_26606586 2.661 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_48828820 2.653 EMP3
epithelial membrane protein 3
chr8_+_37887990 2.635 NM_004095
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
chr19_-_50143350 2.610 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr19_-_1512997 2.597 ADAMTSL5
ADAMTS-like 5
chr5_+_156887026 2.592 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr9_+_504661 2.589 NM_015158
KANK1
KN motif and ankyrin repeat domains 1
chr4_+_156680603 2.581 GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr16_+_30194730 2.554 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr6_+_151187064 2.542 MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr15_-_74494851 2.529 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr6_+_74405909 2.525 CD109
CD109 molecule
chr16_+_30194925 2.517 CORO1A
coronin, actin binding protein, 1A
chr3_-_48130283 2.507 MAP4
microtubule-associated protein 4
chr11_-_441956 2.498 ANO9
anoctamin 9
chr4_+_142557722 2.493 NM_000585
NM_172175
IL15

interleukin 15

chr4_+_75480628 2.484 NM_001657
AREG
amphiregulin
chr1_+_1072274 2.480 LOC254099
uncharacterized LOC254099
chr6_-_30652434 2.471 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_-_51522953 2.466 NM_145888
KLK10
kallikrein-related peptidase 10
chr1_+_15736387 2.446 NM_024329
EFHD2
EF-hand domain family, member D2
chr10_+_134351272 2.428 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr6_+_34204576 2.423 NM_002131
NM_145899
NM_145903
HMGA1


high mobility group AT-hook 1


chr19_-_44285407 2.391 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr7_+_143058794 2.387 ZYX
zyxin
chr15_-_74494780 2.385 STRA6
stimulated by retinoic acid gene 6 homolog (mouse)
chr17_-_1389013 2.374 NM_001080950
MYO1C
myosin IC
chr8_-_25315791 2.358 KCTD9
potassium channel tetramerisation domain containing 9
chr9_-_136344182 2.354 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr10_-_135090325 2.353 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_-_214724565 2.327 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr7_+_48128738 2.311 NM_003364
UPP1
uridine phosphorylase 1
chr7_+_143079925 2.291 ZYX
zyxin
chr7_+_77166750 2.287 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr2_-_113542970 2.264 NM_000575
IL1A
interleukin 1, alpha
chr4_+_75310852 2.262 NM_001657
AREG
amphiregulin
chr10_+_120967094 2.260 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr10_+_75532043 2.246 NM_173540
FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr7_-_102920840 2.235 DPY19L2P2
dpy-19-like 2 pseudogene 2 (C. elegans)
chr11_+_124933007 2.235 NM_001145290
NM_198277
SLC37A2

solute carrier family 37 (glycerol-3-phosphate transporter), member 2

chr2_-_26205437 2.221 NM_002254
KIF3C
kinesin family member 3C
chrX_+_56258785 2.196 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chr6_-_41863086 2.186 NM_018561
USP49
ubiquitin specific peptidase 49
chr21_+_45139018 2.176


chr12_+_130647002 2.166 NM_007197
FZD10
frizzled family receptor 10
chr6_+_34204663 2.139 HMGA1
high mobility group AT-hook 1
chr16_-_87903028 2.132 NM_003486
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr7_+_100770378 2.131 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr7_+_73703704 2.121 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr6_+_34204647 2.108 NM_145901
NM_145902
HMGA1

high mobility group AT-hook 1

chr17_+_7210841 2.078 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr18_+_56338783 2.074 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr1_-_22263676 2.071 NM_005529
HSPG2
heparan sulfate proteoglycan 2
chr7_-_102257199 2.064 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr2_+_192542860 2.046 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr12_+_56522202 2.044 ESYT1
extended synaptotagmin-like protein 1
chr11_-_119187811 2.029 NM_006500
MCAM
melanoma cell adhesion molecule
chr9_+_5629110 2.019 NM_001135920
NM_001206557
NM_020829
KIAA1432


KIAA1432


chr2_-_216300770 2.019 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr19_+_47105327 2.007 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr5_-_127873734 2.006 NM_001999
FBN2
fibrillin 2
chr22_-_36784001 2.005 MYH9
myosin, heavy chain 9, non-muscle
chr9_-_35732389 2.003 NM_006289
TLN1
talin 1
chr1_-_26232643 2.003 NM_203401
STMN1
stathmin 1
chr1_-_6557448 2.002 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr22_+_45098091 1.996 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr11_+_394238 1.988 PKP3
plakophilin 3
chr3_-_197024879 1.987 DLG1
discs, large homolog 1 (Drosophila)
chr19_-_51523272 1.985 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr19_+_2096792 1.985 NM_001031735
NM_001039846
IZUMO4

IZUMO family member 4

chrX_-_54521866 1.981 FGD1
FYVE, RhoGEF and PH domain containing 1
chr1_+_150521786 1.952 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr11_+_124933197 1.951 SLC37A2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr19_-_2046229 1.951 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr12_-_30907447 1.945 NM_001002259
NM_001206856
NM_023925
NM_032156
CAPRIN2



caprin family member 2



chr9_-_35732175 1.939 TLN1
talin 1
chr16_-_88729487 1.938 NM_002461
MVD
mevalonate (diphospho) decarboxylase
chr16_+_66638652 1.928 CMTM3
CKLF-like MARVEL transmembrane domain containing 3
chr12_-_47473424 1.925 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr1_-_26232890 1.925 NM_001145454
NM_005563
STMN1

stathmin 1

chr5_-_171615095 1.923 STK10
serine/threonine kinase 10
chr21_-_40685545 1.913 BRWD1
bromodomain and WD repeat domain containing 1
chrX_+_118533257 1.913 NM_145305
SLC25A43
solute carrier family 25, member 43
chr19_-_14629160 1.911 NM_006145
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr5_+_95998678 1.901 CAST
calpastatin
chr18_+_56338818 1.897 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
chr19_-_15311773 1.894 NM_000435
NOTCH3
notch 3
chr19_-_44285012 1.894 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_155948934 1.891 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_+_41725098 1.890 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr21_-_44496423 1.885 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chrX_+_135230736 1.877 NM_001159700
FHL1
four and a half LIM domains 1
chr10_+_112257624 1.865 NM_004419
DUSP5
dual specificity phosphatase 5
chr5_+_52776408 1.864 FST
follistatin
chr22_-_36784055 1.860 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr11_+_124735281 1.858 NM_022370
ROBO3
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr20_-_56285576 1.857 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 5.22e-26 GO:0009987 cellular process
1.32 1.56e-21 GO:0023052 signaling
1.32 6.61e-20 GO:0007165 signal transduction
1.16 9.92e-17 GO:0065007 biological regulation
1.26 2.02e-16 GO:0051716 cellular response to stimulus
1.16 1.65e-14 GO:0050789 regulation of biological process
1.17 3.76e-14 GO:0050794 regulation of cellular process
1.35 5.18e-09 GO:0023051 regulation of signaling
1.39 5.37e-09 GO:0035556 intracellular signal transduction
1.37 2.36e-08 GO:0009966 regulation of signal transduction
1.15 2.69e-08 GO:0050896 response to stimulus
1.20 3.96e-08 GO:0032502 developmental process
1.31 7.03e-08 GO:0048583 regulation of response to stimulus
1.23 7.40e-08 GO:0048856 anatomical structure development
1.21 1.63e-07 GO:0016043 cellular component organization
1.47 1.91e-07 GO:0051128 regulation of cellular component organization
1.52 6.46e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.28 7.21e-07 GO:0030154 cell differentiation
1.44 8.00e-07 GO:0048699 generation of neurons
1.43 8.90e-07 GO:0022008 neurogenesis
1.27 1.17e-06 GO:0048869 cellular developmental process
2.10 1.36e-06 GO:0034330 cell junction organization
1.20 1.48e-06 GO:0007275 multicellular organismal development
1.22 1.88e-06 GO:0048731 system development
1.58 2.31e-06 GO:0007010 cytoskeleton organization
1.39 3.68e-06 GO:0006793 phosphorus metabolic process
1.39 3.68e-06 GO:0006796 phosphate metabolic process
1.39 4.23e-06 GO:0032268 regulation of cellular protein metabolic process
1.19 4.58e-06 GO:0071840 cellular component organization or biogenesis
1.19 5.81e-06 GO:0051179 localization
1.55 5.96e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.31 6.11e-06 GO:0009653 anatomical structure morphogenesis
2.11 6.81e-06 GO:0034329 cell junction assembly
1.51 7.33e-06 GO:0042060 wound healing
1.37 1.14e-05 GO:0010646 regulation of cell communication
1.31 1.24e-05 GO:0007399 nervous system development
1.22 1.42e-05 GO:0071842 cellular component organization at cellular level
2.15 1.57e-05 GO:0007265 Ras protein signal transduction
1.27 2.39e-05 GO:0006464 protein modification process
1.27 2.86e-05 GO:0007166 cell surface receptor linked signaling pathway
1.77 3.12e-05 GO:0030036 actin cytoskeleton organization
1.43 3.40e-05 GO:0006468 protein phosphorylation
1.35 3.53e-05 GO:0051246 regulation of protein metabolic process
1.80 4.83e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.56 5.44e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.69 5.50e-05 GO:0030029 actin filament-based process
1.22 6.50e-05 GO:0048522 positive regulation of cellular process
1.55 9.66e-05 GO:0048812 neuron projection morphogenesis
1.20 1.28e-04 GO:0048518 positive regulation of biological process
1.57 1.72e-04 GO:0007264 small GTPase mediated signal transduction
1.44 1.90e-04 GO:0030030 cell projection organization
1.24 2.09e-04 GO:0043412 macromolecule modification
1.23 2.11e-04 GO:0048523 negative regulation of cellular process
1.55 2.18e-04 GO:0007409 axonogenesis
1.20 2.19e-04 GO:0071841 cellular component organization or biogenesis at cellular level
1.61 3.19e-04 GO:0007411 axon guidance
1.50 3.82e-04 GO:0031175 neuron projection development
1.21 3.91e-04 GO:0048519 negative regulation of biological process
1.34 4.49e-04 GO:0032879 regulation of localization
1.49 4.62e-04 GO:0000904 cell morphogenesis involved in differentiation
1.21 5.81e-04 GO:0042221 response to chemical stimulus
1.39 6.12e-04 GO:0016192 vesicle-mediated transport
1.55 6.18e-04 GO:0010627 regulation of intracellular protein kinase cascade
1.41 6.62e-04 GO:0030182 neuron differentiation
1.41 6.98e-04 GO:0042325 regulation of phosphorylation
1.48 7.00e-04 GO:0007599 hemostasis
1.48 7.85e-04 GO:0007596 blood coagulation
1.48 7.85e-04 GO:0050817 coagulation
1.20 1.01e-03 GO:0044267 cellular protein metabolic process
1.70 1.02e-03 GO:0051129 negative regulation of cellular component organization
1.37 1.17e-03 GO:0031399 regulation of protein modification process
1.47 1.26e-03 GO:0048858 cell projection morphogenesis
1.47 1.30e-03 GO:0032990 cell part morphogenesis
1.41 1.43e-03 GO:0001932 regulation of protein phosphorylation
1.39 1.53e-03 GO:0019220 regulation of phosphate metabolic process
1.39 1.53e-03 GO:0051174 regulation of phosphorus metabolic process
1.43 1.64e-03 GO:0048666 neuron development
1.39 1.86e-03 GO:0045595 regulation of cell differentiation
1.45 1.97e-03 GO:0023056 positive regulation of signaling
1.17 2.18e-03 GO:0006810 transport
1.45 2.21e-03 GO:0010647 positive regulation of cell communication
1.10 2.59e-03 GO:0044238 primary metabolic process
1.33 2.65e-03 GO:0009611 response to wounding
1.28 2.93e-03 GO:0051239 regulation of multicellular organismal process
1.17 2.99e-03 GO:0051234 establishment of localization
1.21 3.01e-03 GO:0065008 regulation of biological quality
1.50 3.18e-03 GO:0007243 intracellular protein kinase cascade
1.50 3.18e-03 GO:0023014 signal transduction via phosphorylation event
1.17 3.28e-03 GO:0019538 protein metabolic process
1.45 4.25e-03 GO:0009967 positive regulation of signal transduction
1.34 4.93e-03 GO:0016310 phosphorylation
1.42 5.03e-03 GO:0050878 regulation of body fluid levels
1.31 5.49e-03 GO:0007154 cell communication
1.76 7.44e-03 GO:0051493 regulation of cytoskeleton organization
1.25 7.99e-03 GO:0065009 regulation of molecular function
1.10 1.03e-02 GO:0044237 cellular metabolic process
1.27 1.13e-02 GO:0050790 regulation of catalytic activity
1.58 1.16e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.31 1.19e-02 GO:0050793 regulation of developmental process
1.86 1.38e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.83 1.66e-02 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
1.42 1.67e-02 GO:0019226 transmission of nerve impulse
1.42 1.67e-02 GO:0035637 multicellular organismal signaling
1.94 1.79e-02 GO:0032956 regulation of actin cytoskeleton organization
1.84 1.81e-02 GO:0022604 regulation of cell morphogenesis
1.38 2.01e-02 GO:0000902 cell morphogenesis
1.28 2.18e-02 GO:0007049 cell cycle
1.32 2.29e-02 GO:0022402 cell cycle process
1.37 2.38e-02 GO:0032989 cellular component morphogenesis
1.43 2.51e-02 GO:0045859 regulation of protein kinase activity
1.77 2.70e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
2.07 2.78e-02 GO:0007015 actin filament organization
1.40 3.26e-02 GO:0006753 nucleoside phosphate metabolic process
1.40 3.26e-02 GO:0009117 nucleotide metabolic process
1.38 3.33e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.51 3.70e-02 GO:0060284 regulation of cell development
1.93 3.79e-02 GO:0031589 cell-substrate adhesion
2.81 4.04e-02 GO:0007044 cell-substrate junction assembly
1.38 4.13e-02 GO:0006928 cellular component movement
1.88 4.36e-02 GO:0032970 regulation of actin filament-based process
1.08 4.40e-02 GO:0008152 metabolic process
1.27 4.52e-02 GO:0022607 cellular component assembly
1.32 4.71e-02 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 3.95e-28 GO:0005737 cytoplasm
1.41 1.05e-18 GO:0005829 cytosol
1.18 1.41e-14 GO:0044444 cytoplasmic part
1.08 6.20e-11 GO:0044424 intracellular part
1.08 2.02e-10 GO:0005622 intracellular
1.32 6.63e-08 GO:0005856 cytoskeleton
1.26 7.54e-08 GO:0044459 plasma membrane part
1.90 7.72e-06 GO:0070161 anchoring junction
2.15 2.37e-05 GO:0005925 focal adhesion
1.89 5.67e-05 GO:0005912 adherens junction
1.25 1.22e-04 GO:0012505 endomembrane system
2.04 1.47e-04 GO:0005924 cell-substrate adherens junction
1.17 1.84e-04 GO:0043234 protein complex
1.67 1.99e-04 GO:0016323 basolateral plasma membrane
1.35 2.64e-04 GO:0031982 vesicle
1.58 3.82e-04 GO:0015629 actin cytoskeleton
1.35 4.00e-04 GO:0031410 cytoplasmic vesicle
1.50 4.45e-04 GO:0043005 neuron projection
1.13 5.27e-04 GO:0071944 cell periphery
1.97 5.52e-04 GO:0030055 cell-substrate junction
1.13 6.96e-04 GO:0005886 plasma membrane
1.39 1.19e-03 GO:0030054 cell junction
1.31 1.84e-03 GO:0042995 cell projection
1.34 2.38e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 2.64e-03 GO:0031988 membrane-bounded vesicle
1.27 3.36e-03 GO:0000267 cell fraction
1.65 7.03e-03 GO:0031252 cell leading edge
1.25 1.10e-02 GO:0044430 cytoskeletal part
1.63 1.61e-02 GO:0030424 axon
1.15 1.63e-02 GO:0043228 non-membrane-bounded organelle
1.15 1.63e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.07 1.64e-02 GO:0016020 membrane
1.32 1.81e-02 GO:0015630 microtubule cytoskeleton
1.03 1.86e-02 GO:0044464 cell part
1.03 1.96e-02 GO:0005623 cell
1.43 2.25e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 6.60e-27 GO:0005515 protein binding
1.08 8.04e-12 GO:0005488 binding
1.41 1.45e-05 GO:0042802 identical protein binding
1.41 2.06e-05 GO:0019899 enzyme binding
1.52 6.91e-05 GO:0019904 protein domain specific binding
1.43 1.01e-04 GO:0004672 protein kinase activity
1.51 1.20e-04 GO:0004674 protein serine/threonine kinase activity
1.45 1.52e-04 GO:0008092 cytoskeletal protein binding
1.34 1.66e-04 GO:0030234 enzyme regulator activity
1.38 3.01e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.47 5.38e-04 GO:0030695 GTPase regulator activity
1.45 1.00e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.35 1.07e-03 GO:0016301 kinase activity
1.55 1.12e-03 GO:0003779 actin binding
1.58 4.73e-03 GO:0005096 GTPase activator activity
1.21 5.43e-03 GO:0016740 transferase activity
1.59 5.83e-03 GO:0019900 kinase binding
1.71 6.45e-03 GO:0000287 magnesium ion binding
1.20 6.47e-03 GO:0032553 ribonucleotide binding
1.20 6.47e-03 GO:0032555 purine ribonucleotide binding
1.20 7.12e-03 GO:0017076 purine nucleotide binding
1.43 8.33e-03 GO:0042803 protein homodimerization activity
1.44 1.29e-02 GO:0008047 enzyme activator activity
1.28 1.62e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.19 1.96e-02 GO:0035639 purine ribonucleoside triphosphate binding
2.74 3.09e-02 GO:0008060 ARF GTPase activator activity
1.59 3.35e-02 GO:0019901 protein kinase binding
1.16 4.50e-02 GO:0000166 nucleotide binding