Motif ID: ZNF148.p2

Z-value: 2.149


Transcription factors associated with ZNF148.p2:

Gene SymbolEntrez IDGene Name
ZNF148 7707 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF148chr3_-_125094003-0.571.1e-03Click!


Activity profile for motif ZNF148.p2.

activity profile for motif ZNF148.p2


Sorted Z-values histogram for motif ZNF148.p2

Sorted Z-values for motif ZNF148.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF148.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_4135701 9.345 NM_001166010
NM_006117
NM_206836
 ECI2


enoyl-CoA delta isomerase 2


chr8_+_86376130 8.230 NM_000067
 CA2
carbonic anhydrase II
chr20_+_3776905 7.828 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr19_+_35645640 7.710 NM_144779
NM_001164605
 FXYD5

FXYD domain containing ion transport regulator 5

chr19_+_35645614 7.486 NM_014164
 FXYD5
FXYD domain containing ion transport regulator 5
chr1_-_20812271 7.459 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_35646006 7.147 FXYD5
FXYD domain containing ion transport regulator 5
chr12_-_122231554 6.886 NM_019034
 RHOF
ras homolog gene family, member F (in filopodia)
chrX_-_153599719 6.336 FLNA
filamin A, alpha
chr19_-_51845377 6.095 NM_001163922
 VSIG10L
V-set and immunoglobulin domain containing 10 like
chr12_-_125348266 5.724 SCARB1
scavenger receptor class B, member 1
chrX_-_153599581 5.577 FLNA
filamin A, alpha
chr19_+_6531009 5.495 NM_003811
 TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_+_32050510 5.072 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr19_-_19052032 4.989 NM_004838
 HOMER3
homer homolog 3 (Drosophila)
chr19_+_2096930 4.853 IZUMO4
IZUMO family member 4
chr6_+_37137882 4.826 NM_001243186
NM_002648
 PIM1

pim-1 oncogene

chr19_-_19051899 4.803 HOMER3
homer homolog 3 (Drosophila)
chr22_-_37915209 4.631 NM_014550
 CARD10
caspase recruitment domain family, member 10
chr12_-_125348422 4.554 NM_001082959
NM_005505
 SCARB1

scavenger receptor class B, member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 123 entries
enrichment   p-value GO term description
2.81 4.04e-02 GO:0007044 cell-substrate junction assembly
2.15 1.57e-05 GO:0007265 Ras protein signal transduction
2.11 6.81e-06 GO:0034329 cell junction assembly
2.10 1.36e-06 GO:0034330 cell junction organization
2.07 2.78e-02 GO:0007015 actin filament organization
1.94 1.79e-02 GO:0032956 regulation of actin cytoskeleton organization
1.93 3.79e-02 GO:0031589 cell-substrate adhesion
1.88 4.36e-02 GO:0032970 regulation of actin filament-based process
1.86 1.38e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.84 1.81e-02 GO:0022604 regulation of cell morphogenesis
1.83 1.66e-02 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
1.80 4.83e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.77 3.12e-05 GO:0030036 actin cytoskeleton organization
1.77 2.70e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
1.76 7.44e-03 GO:0051493 regulation of cytoskeleton organization
1.70 1.02e-03 GO:0051129 negative regulation of cellular component organization
1.69 5.50e-05 GO:0030029 actin filament-based process
1.61 3.19e-04 GO:0007411 axon guidance
1.58 2.31e-06 GO:0007010 cytoskeleton organization
1.58 1.16e-02 GO:0010740 positive regulation of intracellular protein kinase cascade

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.15 2.37e-05 GO:0005925 focal adhesion
2.04 1.47e-04 GO:0005924 cell-substrate adherens junction
1.97 5.52e-04 GO:0030055 cell-substrate junction
1.90 7.72e-06 GO:0070161 anchoring junction
1.89 5.67e-05 GO:0005912 adherens junction
1.67 1.99e-04 GO:0016323 basolateral plasma membrane
1.65 7.03e-03 GO:0031252 cell leading edge
1.63 1.61e-02 GO:0030424 axon
1.58 3.82e-04 GO:0015629 actin cytoskeleton
1.50 4.45e-04 GO:0043005 neuron projection
1.43 2.25e-02 GO:0048471 perinuclear region of cytoplasm
1.41 1.05e-18 GO:0005829 cytosol
1.39 1.19e-03 GO:0030054 cell junction
1.35 2.64e-04 GO:0031982 vesicle
1.35 4.00e-04 GO:0031410 cytoplasmic vesicle
1.34 2.38e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.33 2.64e-03 GO:0031988 membrane-bounded vesicle
1.32 6.63e-08 GO:0005856 cytoskeleton
1.32 1.81e-02 GO:0015630 microtubule cytoskeleton
1.31 1.84e-03 GO:0042995 cell projection

Gene overrepresentation in function category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
2.74 3.09e-02 GO:0008060 ARF GTPase activator activity
1.71 6.45e-03 GO:0000287 magnesium ion binding
1.59 5.83e-03 GO:0019900 kinase binding
1.59 3.35e-02 GO:0019901 protein kinase binding
1.58 4.73e-03 GO:0005096 GTPase activator activity
1.55 1.12e-03 GO:0003779 actin binding
1.52 6.91e-05 GO:0019904 protein domain specific binding
1.51 1.20e-04 GO:0004674 protein serine/threonine kinase activity
1.47 5.38e-04 GO:0030695 GTPase regulator activity
1.45 1.52e-04 GO:0008092 cytoskeletal protein binding
1.45 1.00e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.44 1.29e-02 GO:0008047 enzyme activator activity
1.43 1.01e-04 GO:0004672 protein kinase activity
1.43 8.33e-03 GO:0042803 protein homodimerization activity
1.41 1.45e-05 GO:0042802 identical protein binding
1.41 2.06e-05 GO:0019899 enzyme binding
1.38 3.01e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.35 1.07e-03 GO:0016301 kinase activity
1.34 1.66e-04 GO:0030234 enzyme regulator activity
1.28 1.62e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups